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All mouse models of cell type benign neoplasm with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | arteriovenous malformations of the brain | Engtm2.1Hma/Engtm2.1Hma | involves: 129P2/OlaHsd | J:196810 | View | |||
| arteriovenous malformations of the brain |
Krastm4Tyj/Kras+ Tg(Cdh5-cre/ERT2)1Rha/0 |
involves: 129S4/SvJae * FVB | J:312482 | View | ||||
| arteriovenous malformations of the brain |
Krastm4Tyj/Kras+ Tg(Slco1c1-icre/ERT2)1Mrks/0 |
involves: 129S4/SvJae * C57BL/6 * DBA/2 * FVB | J:312482 | View | ||||
| von Hippel-Lindau disease |
Hif1atm3Rsjo/Hif1atm3Rsjo Hprt1tm1(Pck1-cre)Vhh/Y Vhltm1Jae/Vhltm1Jae |
involves: 129 * BALB/c * C57BL/6 | J:97652, J:106705 | View | ||||
| von Hippel-Lindau disease |
Hif1atm3Rsjo/Hif1atm3Rsjo Vhltm1Jae/Vhltm1Jae Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129 * BALB/c * C57BL/6 * DBA | J:97652 | View | ||||
| von Hippel-Lindau disease |
Hprt1tm1(Pck1-cre)Vhh/Y Vhltm1Jae/Vhltm1Jae |
involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c * C57BL/6 | J:97652, J:106705 | View | ||||
| von Hippel-Lindau disease |
Ptentm1Hwu/Ptentm1Hwu Vhltm1Jae/Vhltm1Jae Tg(Cdh16-cre)91Igr/0 |
involves: 129S4/SvJae * BALB/c * C57BL/6J * ICR | J:137073 | View | ||||
| von Hippel-Lindau disease |
Ptentm1Hwu/Ptentm1Hwu Vhltm1Jae/Vhltm1Jae Tg(Cdh16-cre)91Igr/0 |
involves: 129S4/SvJae * ICR | J:137442 | View | ||||
| von Hippel-Lindau disease | Vhltm1.1Jae/Vhl+ | involves: 129S4/SvJae * BALB/c | J:67505 | View | ||||
| von Hippel-Lindau disease | Vhltm1.1Lss/Vhl+ | involves: A/J | J:85513 | View | ||||
| von Hippel-Lindau disease | Vhltm1.1Lss/Vhl+ | involves: BALB/c | J:85513 | View | ||||
| von Hippel-Lindau disease | Vhltm1.1Wkr/Vhl+ | involves: 129S4/SvJae * C57BL/6 | J:157369 | View | ||||
| von Hippel-Lindau disease |
Vhltm1Jae/Vhltm1Jae Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129S4/SvJae * BALB/c * C57BL/6 * DBA | J:67505, J:97652 | View | ||||
| von Hippel-Lindau disease | Vhltm1Lss/Vhltm1.1Lss | involves: 129X1/SvJ * C57BL/6 | J:85513 | View | ||||
| von Hippel-Lindau disease |
Vhltm1Lss/Vhltm1.1Lss Tg(ACTB-cre)1Tes/0 |
involves: 129X1/SvJ * C3H * C57BL/6 | J:85513 | View | ||||
| von Hippel-Lindau disease |
Vhltm1Lss/Vhltm1Lss Tg(Gcg-cre)1Slib/0 |
either: (involves: 129X1/SvJ * A/J) or (involves: 129X1/SvJ * C57BL/6) | J:148174 | View | ||||
| von Hippel-Lindau disease |
Vhltm1Lss/Vhltm1Lss Tg(Ins2-cre)25Mgn/0 |
either: (involves: 129X1/SvJ * C57BL/6 * DBA) or (involves: 129X1/SvJ * A/J * C57BL/6 * DBA) | J:148174 | View | ||||
| von Hippel-Lindau disease |
Vhltm1Lss/Vhltm1Lss Tg(Pdx1-cre)89.1Dam/0 |
involves: 129X1/SvJ * C57BL/6 * CBA | J:148174 | View | ||||
| von Hippel-Lindau disease | Vhltm1Wml/Vhltm1Wml | involves: 129S4/SvJae * C57BL/6 | J:42846, J:88492 | View | ||||
| | arteriovenous malformations of the brain | Acvrl1tm2.1Spo/Acvrl1tm2.1Spo | involves: 129 | J:196810 | View | |||
| arteriovenous malformations of the brain |
Tg(Tek-tTA)1Rwng/0 Tg(tetO-Notch4*)1Rwng/0 |
involves: FVB/N | J:139943 | View | ||||
| dermoid cyst of ovary |
Foxo3mommeR1/Foxo3mommeR1 Tg(HBA1-GFP)1Ew/Tg(HBA1-GFP)1Ew |
FVB/NJ-Foxo3mommeR1 Tg(HBA1-Gfp)1Ew | J:170710 | View | ||||
| growth hormone secreting pituitary adenoma | Men1tm1Zqw/Men1+ | involves: 129/Sv * 129P2/OlaHsd | J:85302 | View | ||||
| hepatocellular adenoma |
Ptpn11tm1Gsf/Ptpn11tm1Gsf Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA | J:172422 | View | ||||
| prolactinoma | Men1tm1Zqw/Men1+ | involves: 129/Sv * 129P2/OlaHsd | J:85302 | View | ||||
| Transgenes and Other Mutations | ACTH-secreting pituitary adenoma | Tg(PyLT)1Vb/0 | Not Specified | J:55528 | View | |||
| choroid plexus papilloma |
Smarcb1tm1Sho/Smarcb1+ Tg(LPV-TAg121)2Tvd/0 |
involves: 129S6/SvEvTac * C57BL/6J * DBA/2J | J:120820 | View | ||||
| choroid plexus papilloma | Tg(LPV-TAg121)2Tvd/0 | involves: 129S6/SvEvTac * C57BL/6J * DBA/2J | J:120820 | View | ||||
| dermoid cyst of ovary | Tg(Amh-SMAD2*)#Jebu/0 | FVB/N-Tg(Amh-SMAD2*)#Jebu | J:200783 | View | ||||
| insulinoma | Tg(RIP1-Tag)2Dh/0 | involves: C57BL/6J * DBA/2J | J:205389 | View | ||||
| prolactinoma | Tg(Prl-EGFR)#Sme/0 | Not Specified | J:219654 | View | ||||
| von Hippel-Lindau disease | Tg(Ggt1-Hif1a*)43Log/0 | involves: C57BL/6 | J:177381 | View | ||||
| Additional Complex Models | adenoma |
Krastm4Tyj/Kras+ Ptf1atm1.1(cre)Cvw/Ptf1a+ Tg(MUC1)79.24Gend/0 |
B6.Cg-Krastm4Tyj Ptf1atm1.1(cre)Cvw Tg(MUC1)79.24Gend | J:138959 | View | |||
| adenoma |
Rb1tm2Brn/Rb1tm2Brn Trp53tm1Brn/Trp53tm1Brn Tg(Ren-cre)#Kwg/0 |
involves: 129 * 129P2/OlaHsd | J:216559 | View | ||||
| seborrheic keratosis |
Psen1tm1Bdes/Psen1+ Psen2tm1Bdes/Psen2tm1Bdes |
involves: 129P2/OlaHsd | J:91235 | View | ||||