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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
![]() ![]() | pheochromocytoma | Rettm2.1Cos/Rettm2.1Cos | involves: 129S1/Sv * C57BL/6J * FVB/N | J:60659 | View | |||
![]() | growth hormone secreting pituitary adenoma | Men1tm1Zqw/Men1+ | involves: 129/Sv * 129P2/OlaHsd | J:85302 | View | |||
hepatocellular adenoma |
Ptpn11tm1Gsf/Ptpn11tm1Gsf Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA | J:172422 | View | ||||
prolactinoma | Men1tm1Zqw/Men1+ | involves: 129/Sv * 129P2/OlaHsd | J:85302 | View | ||||
![]() | pheochromocytoma |
Ptentm1Mro/Ptentm1Mro Sdhbtm1.1Ics/Sdhb+ Tg(KLK3-cre)D4Trp/0 |
involves: 129S2/SvPas * FVB | J:236514 | View | |||
Transgenes and Other Mutations | ACTH-secreting pituitary adenoma | Tg(PyLT)1Vb/0 | Not Specified | J:55528 | View | |||
prolactinoma | Tg(Prl-EGFR)#Sme/0 | Not Specified | J:219654 | View |
No similarity to the expected human disease phenotype was found.
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
NOT Models | paraganglioma |
Sdhctm1c(EUCOMM)Wtsi/Sdhctm1c(EUCOMM)Wtsi Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+ |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N | J:284745 | View | |||
paraganglioma | Sdhdtm1Jlob/Sdhd+ | involves: 129X1/SvJ | J:95252 | View | ||||
paraganglioma | Sdhdtm1Jlob/Sdhdtm1Jlob | involves: 129X1/SvJ | J:95252 | View | ||||
paraganglioma | Sdhdtm1Jpb/Sdhd+ | either: 129P2/OlaHsd-Sdhdtm1Jpb or (involves: 129P2/OlaHsd * C57BL/6J) | J:155380 | View | ||||
pheochromocytoma | Rettm1Cos/Rettm2.1Cos | involves: 129S/SvEv * 129S1/Sv * C57BL/6J * FVB/N * MF1 | J:60659 | View |