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All mouse models of musculoskeletal system cancer with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | osteosarcoma |
Prkar1atm1.2Lsk/Prkar1a+ Rb1tm2Brn/Rb1+ Tg(Col1a1-cre)1Kry/0 Trp53tm1Brn/Trp53tm1Brn |
involves: 129 * 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N | J:234128 | View | |||
| osteosarcoma |
Prkar1atm1.2Lsk/Prkar1a+ Rb1tm2Brn/Rb1tm2Brn Trp53tm1Brn/Trp53tm1Brn Tg(Col1a1-cre)1Kry/0 |
involves: 129 * 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N | J:234128 | View | ||||
| osteosarcoma |
Prkar1atm1.2Lsk/Prkar1a+ Tg(Col1a1-cre)1Kry/0 Trp53tm1Brn/Trp53tm1Brn |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N | J:234128 | View | ||||
| osteosarcoma |
Ptch1tm1Yy/Ptch1+ Trp53tm1Brd/Trp53+ Tg(BGLAP-cre)1Clem/0 |
involves: 129S7/SvEvBrd * C57BL/6 * FVB/NJ | J:214349 | View | ||||
| osteosarcoma |
Rb1tm3Tyj/Rb1+ Trp53tm1Brn/Trp53tm1Brn Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J * CD-1 * FVB/N | J:136693 | View | ||||
| osteosarcoma |
Rb1tm3Tyj/Rb1tm3Tyj Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 Tg(tetO-RNAi:Trp53)ASlowe/0 |
involves: 129S4/SvJae * C57BL/6 * CD-1 | J:199542 | View | ||||
| osteosarcoma |
Rb1tm3Tyj/Rb1tm3Tyj Trp53tm1Brn/Trp53tm1Brn Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * CD-1 | J:199542 | View | ||||
| osteosarcoma |
Rb1tm3Tyj/Rb1tm3Tyj Trp53tm1Brn/Trp53tm1Brn Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J * CD-1 * FVB/N | J:136693, J:318035 | View | ||||
| osteosarcoma |
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 Tg(tetO-RNAi:Trp53)ASlowe/0 |
involves: C57BL/6 * CD-1 | J:199542 | View | ||||
| osteosarcoma |
Trp53tm1Brn/Trp53tm1Brn Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 |
involves: 129P2/OlaHsd * C57BL/6 * CD-1 | J:199542 | View | ||||
| | liposarcoma | Tg(Fabp4-Il22)#Ychn/0 | involves: ICR | J:176141 | View | |||
| | alveolar rhabdomyosarcoma |
Cdkn2atm4Rdp/Cdkn2atm4Rdp Myf6tm1(cre)Mrc/Myf6+ Pax3tm1Mrc/Pax3tm1Mrc |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL | J:93444 | View | |||
| alveolar rhabdomyosarcoma |
Myf6tm1(cre)Mrc/Myf6+ Pax3tm1Mrc/Pax3+ |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL | J:93444 | View | ||||
| alveolar rhabdomyosarcoma |
Myf6tm1(cre)Mrc/Myf6+ Pax3tm1Mrc/Pax3tm1Mrc Trp53tm1Brn/Trp53+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL | J:93444 | View | ||||
| alveolar rhabdomyosarcoma |
Myf6tm1(cre)Mrc/Myf6+ Pax3tm1Mrc/Pax3tm1Mrc Trp53tm1Brn/Trp53tm1Brn |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL | J:93444 | View | ||||
| Transgenes and Other Mutations | Kaposi's sarcoma | Tg(Acta2-RAC1*G12V)33Pjgc/0 | involves: C57BL/6 * FVB/N | J:150015 | View | |||
| Kaposi's sarcoma | Tg(Acta2-RAC1*G12V)33Pjgc/Tg(Acta2-RAC1*G12V)33Pjgc | involves: C57BL/6 * FVB/N | J:150015 | View | ||||
| osteosarcoma | Tg(Bglap2-TAg)1Rkho/0 | FVB/N-Tg(Bglap2-TAg)1Rkho | J:165282 | View | ||||
| osteosarcoma | Tg(Bglap2-TAg)1Rkho/0 | involves: FVB/N | J:234128 | View | ||||
| Additional Complex Models | alveolar soft part sarcoma | Gt(ROSA)26Sortm5(ASPSCR1/TFE3)Mrc/Gt(ROSA)26Sortm1(cre/ERT)Nat | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:217462 | View | |||
| embryonal rhabdomyosarcoma |
Cdkn2atm1Cjs/Cdkn2atm1Cjs Tg(CKMM-tTA)A3Rhvh/0 Tg(tetO-Hgf,-EGFP)24Tcre/0 |
involves: 129X1/SvJ * FVB | J:237183 | View | ||||
| myxoid liposarcoma |
Trp53tm1Tyj/Trp53tm1Tyj Tg(Prrx1-FUS/DDIT3)1Mete/0 |
involves: 129S2/SvPas * C57BL/6 * CBA | J:184491 | View | ||||
| rhabdomyosarcoma |
Cdkn2atm1Rdp/Cdkn2atm1Rdp Tg(Mt1-Hgf)19Lmb/0 |
involves: 129/Sv * C57BL/6J * FVB/N * SJL | J:79704 | View | ||||
| synovial sarcoma | Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sortm3(SS18/EGFP)Mrc | involves: 129 * 129S1/Sv * 129X1/SvJ | J:147728 | View | ||||
| synovial sarcoma |
Gt(ROSA)26Sortm2(SS18)Mrc/Gt(ROSA)26Sortm2(SS18)Mrc Myf5tm1(cre)Mrc/Myf5tm1(cre)Mrc |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:120967 | View | ||||
| synovial sarcoma |
Gt(ROSA)26Sortm3(SS18/EGFP)Mrc/Gt(ROSA)26Sortm3(SS18/EGFP)Mrc Myf5tm1(cre)Mrc/Myf5tm1(cre)Mrc |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:120967 | View | ||||