Excel File Text File All mouse models of integumentary system cancer with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      basal cell carcinoma Ptch1tm1Bjw/Ptch1tm1Bjw
Tg(KRT14-cre)8Brn/0		 involves: 129T2/SvEms * FVB/N J:231264 View
basal cell carcinoma Ptch1tm1Hahn/Ptch1tm1Hahn
Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+		 involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ J:158915 View
basal cell carcinoma Ptch1tm1Mps/Ptch1+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2J J:58328 View
      skin cancer Tg(KRT14-Snai1)1Efu/0 involves: CD-1 J:229072 View
skin melanoma Grm1Tg(p18A4.B)1352Szc/0 Not Specified J:83183 View
skin melanoma Tg(Dct-Grm1)ESzc/0 involves: C57BL/6J J:83183 View
skin squamous cell carcinoma Tg(KRT14-Fyn*)aJsey/0 involves: C57BL/6 * CBA * FVB/N J:155536 View
      basal cell carcinoma Dicer1tm1Snj/Dicer1tm1Snj
Trp53tm1Brn/Trp53+
Tg(KRT5-cre/PGR)1Der/0		 involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR J:216813 View
skin melanoma Cdkn2atm1Rdp/Cdkn2a+
Tg(Tyr-NRAS*Q61K)1Bee/?		 involves: 129/Sv * C57BL/6 * DBA/2 * SJL J:98545 View
skin melanoma Cdkn2atm1Rdp/Cdkn2atm1Rdp
Tg(Tyr-NRAS*Q61K)1Bee/?		 involves: 129/Sv * C57BL/6 * DBA/2 * SJL J:98545 View
skin melanoma Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh
Krastm4Tyj/Kras+
Tg(Tyr-cre/ERT2)13Bos/0		 B6J.Cg-Tg(Tyr-cre/ERT2)13Bos Cdkn2atm2.1Nesh Krastm4Tyj J:220627 View
skin melanoma Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh
Nrastm1.1Nesh/Nrastm1.1Nesh
Stk11tm1.1Rdp/Stk11tm1.1Rdp
Tg(Tyr-cre/ERT2)13Bos/0		 B6J.Cg-Tg(Tyr-cre/ERT2)13Bos Nrastm1.1Nesh Cdkn2atm2.1Nesh Stk11tm1.1Rdp J:220627 View
skin melanoma Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh
Nrastm1.1Nesh/Nrastm1.1Nesh
Tg(Tyr-cre/ERT2)13Bos/0		 B6J.Cg-Tg(Tyr-cre/ERT2)13Bos Nrastm1.1Nesh Cdkn2atm2.1Nesh J:220627 View
Transgenes and
Other Mutations		     skin cancer Tg(KRT14-HPV8)9Vuc/0 FVB.Cg-Tg(KRT14-HPV8)9Vuc J:96784 View
skin cancer Tg(KRT14-HPV8)85Vuc/0 FVB.Cg-Tg(KRT14-HPV8)85Vuc J:96784 View
skin cancer Tg(KRT14-HPV8)#Vuc/0 involves: C57BL/6 * DBA * FVB/N J:96784 View
skin melanoma Tg(CAG-Ptafr)1Tksh/0 B6;D2-Tg(CAG-Ptafr)1Tksh/TkshRbrc J:38639 View
skin melanoma Tg(Mt1-RET)304Ina/0 B6.C-Tg(Mt1-RET)304Ina J:50392 View
skin squamous cell carcinoma Tg(KRT14-HPV16)wt1Dh/0 either: FVB.Cg-Tg(KRT14-HPV16)wt1Dh or (involves: C57BL/6 * DBA/2 * FVB/N) J:20130 View
Additional
Complex
Models		     skin melanoma Braftm1Mmcm/Braf+
Ptentm1Rdp/Ptentm1Rdp
Tg(Tyr-cre/ERT2)13Bos/0		 involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * FVB/N J:151023 View
skin melanoma Braftm1Mmcm/Braf+
Ptentm2.1Ppp/Ptentm2.1Ppp
Tg(Tyr-cre/ERT2)13Bos/0		 involves: 129P2/OlaHsd * 129S1/Sv * FVB J:151023 View
skin melanoma Cdk4tm1.1Bbd/Cdk4tm1.1Bbd
Tg(Mt1-Hgf)#Lmb/0		 B6.Cg-Cdk4tm1.1Bbd Tg(Mt1-Hgf)#Lmb J:111992 View
skin melanoma Cdk4tm1.1Bbd/Cdk4tm1.1Bbd
Tg(Tyr-NRAS*Q61K)1Bee/0		 FVB.Cg-Cdk4tm1.1Bbd Tg(Tyr-NRAS*Q61K)1Bee J:222847 View
skin melanoma Xpatm1Tnka/Xpatm1Tnka
Tg(KRT14-Kitl)1Takk/?		 involves: C57BL/6 * CBA * SJL J:100608 View

       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      skin squamous cell carcinoma Tg(KRT14-HPV16)wt1Dh/0 C.Cg-Tg(KRT14-HPV16)wt1Dh J:20130 View
skin squamous cell carcinoma Tg(KRT14-HPV16)wt1Dh/0 either: (involves: C57BL/6 * DBA/2) or (involves: C57BL/6 * DBA/2 * SENCAR * SSIN) J:20130 View