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All mouse models of Noonan syndrome 1 with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | Noonan syndrome 1 |
Emx1tm1(cre)Krj/Emx1+ Ptpn11tm6Bgn/Ptpn11+ |
B6.129S-Ptpn11tm6Bgn Emx1tm1(cre)Krj | J:242312 | View | |||
| Noonan syndrome 1 | Ptpn11tm1Bgn/Ptpn11+ | involves: 129S4/SvJae * C57BL/6J | J:91609 | View | ||||
| Noonan syndrome 1 | Tg(Myh7-Ptpn11*Q79R)11Rbns/0 | FVB.Cg-Tg(Myh7-Ptpn11*Q79R)11Rbns | J:123963 | View | ||||
| Transgenes and Other Mutations | Noonan syndrome 1 |
H2az2Tg(Wnt1-cre)11Rth/H2az2+ Tg(CAG-cat,-Ptpn11*Q97R)1Rbns/0 |
involves: C57BL/6J * CBA/J * FVB/N | J:153094 | View | |||
| Noonan syndrome 1 |
Tg(CAG-cat,-Ptpn11*Q97R)1Rbns/0 Tg(Tek-cre)12Flv/0 |
involves: C3H * C57BL/6 * FVB/N | J:142212 | View | ||||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | Noonan syndrome 1 | Ptpn11tm1Paw/Ptpn11tm1Paw | involves: 129S1/Sv * 129X1/SvJ * CD-1 | J:43740 | View | |||
| Noonan syndrome 1 | Ptpn11tm1Rbn/Ptpn11+ | involves: 129 * Black Swiss | J:35137 | View | ||||
| Noonan syndrome 1 | Ptpn11tm1Rbn/Ptpn11tm1Rbn | involves: 129 * Black Swiss | J:35137 | View | ||||