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All mouse models of hypomyelinating leukodystrophy with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
hypomyelinating leukodystrophy 2 |
Gjb1tm1Kwi/Y Gjc2tm1(EGFP)Kwi/Gjc2tm1(EGFP)Kwi |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 | J:219594 | View | ||||
hypomyelinating leukodystrophy 2 |
Gjc2tm1(EGFP)Kwi/Gjc2tm1(EGFP)Kwi Gjb1tm1Kwi/Gjb1tm1Kwi |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 | J:219594 | View | ||||
hypomyelinating leukodystrophy 2 | Gjc2tm2.1Kwi/Gjc2tm2.1Kwi | involves: C57BL/6 * SJL | J:174197 | View | ||||
hypomyelinating leukodystrophy 6 | Tubb4aem1Avan/Tubb4aem1Avan | involves: C57BL/6 | J:291062 | View | ||||
hypomyelinating leukodystrophy 6 | Tubb4aJit/Tubb4a+ | FVB.B6-Tubb4aJit | J:321692 | View | ||||
hypomyelinating leukodystrophy 6 | Tubb4aJit/Tubb4aJit | FVB.B6-Tubb4aJit | J:321692 | View | ||||
Pelizaeus-Merzbacher disease | Dp(XTceal3-Plp1)1Gmh/Y | involves: 129S7/SvEvBrd * C57BL/6 | J:199809 | View | ||||
Pelizaeus-Merzbacher disease | Plp1jp-msd/Y | involves: BALB/c * C3H * C57BL/6 * C57BL/10 | J:121540 | View | ||||
Pelizaeus-Merzbacher disease | Plp1jp-rsh/Y | involves: C3H * C57BL/6 * STOCK Rb(1.3)1Bnr | J:121540 | View | ||||
Pelizaeus-Merzbacher disease | Plp1tm1Frca/Y | B6.129-Plp1tm1Frca | J:143305 | View | ||||
Pelizaeus-Merzbacher disease | Plp1tm1Kan/? | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:146665 | View | ||||
Pelizaeus-Merzbacher disease | Tg(Plp)66Kan/0 | B6NCrl.Cg-Tg(Plp)66Kan | J:156106 | View | ||||
Pelizaeus-Merzbacher disease | Tg(Plp)66Kan/Tg(Plp)66Kan | B6NCrl.Cg-Tg(Plp)66Kan | J:156106 | View | ||||
Pelizaeus-Merzbacher disease | Tg(Plp)72Kan/Tg(Plp)72Kan | B6N.Cg-Tg(Plp)72Kan | J:229229 | View |
No similarity to the expected human disease phenotype was found.
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
NOT Models | hypomyelinating leukodystrophy 7 | Polr3aGt(LG04)Osb/Polr3atm1Bebr | involves: C57BL/6 * C57BL/6J * DBA/2 | J:250577 | View | |||
hypomyelinating leukodystrophy 7 | Polr3atm1.1Bebr/Polr3atm1.1Bebr | involves: C57BL/6J | J:250577 | View |