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All mouse models of late onset Parkinson's disease with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | Parkinson's disease 1 | Sncatm1.1Koks/Snca+ | either: B6.129P2-Sncatm1.1Koks or (involves: 129P2/OlaHsd * C57BL/6) | J:201391 | View | |||
| Parkinson's disease 1 |
Sncatm1Nbm/Sncatm1Nbm Tg(SNCA*A30P)1Nbm/Tg(SNCA*A30P)1Nbm Tg(SNCA*A30P)2Nbm/Tg(SNCA*A30P)2Nbm |
involves: 129S6/SvEvTac * FVB/N | J:156741 | View | ||||
| Parkinson's disease 1 |
Sncatm1Nbm/Sncatm1Nbm Tg(SNCA*A53T)1Nbm/Tg(SNCA*A53T)1Nbm Tg(SNCA*A53T)2Nbm/Tg(SNCA*A53T)2Nbm |
involves: 129S6/SvEvTac * FVB/N | J:156741 | View | ||||
| Parkinson's disease 1 | Sncatm1Rosl/Sncatm1Rosl | involves: 129X1/SvJ * C57BL/6 | J:60151 | View | ||||
| Parkinson's disease 1 |
Sncatm1Rosl/Sncatm1Rosl Tg(SNCA)OVX37Rwm/0 |
B6.Cg-Tg(SNCA)OVX37Rwm Sncatm1Rosl | J:201991 | View | ||||
| Parkinson's disease 1 |
Sncatm1Rosl/Sncatm1Rosl Tg(SNCA*A30P)192Rwm/0 |
B6.Cg-Sncatm1Rosl Tg(SNCA*A30P)#Rwm | J:201961 | View | ||||
| Parkinson's disease 4 | Tg(Thy1-Snca)1S13Putt/? | involves: C57BL/6 | J:177661 | View | ||||
| Parkinson's disease 8 | Tg(Lrrk2*G2019S)2Yue/0 | involves: C3H * C57BL/6 * C57BL/6J | J:157931 | View | ||||
| Parkinson's disease 14 | Pla2g6tm1.1Hlw/Pla2g6tm1.1Hlw | involves: 129 * C57BL/6J | J:317126 | View | ||||
| Parkinson's disease 17 | Vps35Gt(RRK261)Byg/Vps35+ | B6.129P2-Vps35Gt(RRK261)Byg | J:225806 | View | ||||
| Parkinson's disease 17 | Vps35tm1.1Hlw/Vps35+ | involves: 129S/SvEv * C57BL/6J | J:329507 | View | ||||
| Transgenes and Other Mutations | Parkinson's disease 1 | Tg(PDGFB-SNCA)4Ema/0 | involves: C57BL/6 * DBA/2 | J:60638, J:166985 | View | |||
| Parkinson's disease 1 | Tg(PDGFB-SNCA*A53T)8Ema/0 | Not Specified | J:226922 | View | ||||
| Parkinson's disease 1 | Tg(PDGFB-SNCA/EGFP)78Ema/0 | involves: C57BL/6 * DBA/2 | J:238692 | View | ||||
| Parkinson's disease 1 | Tg(Prnp-SNCA*A53T)25Mkle/0 | involves: C3H/HeJ * C57BL/6J | J:77344 | View | ||||
| Parkinson's disease 1 | Tg(Prnp-SNCA*A53T)83Vle/0 | involves: C3H * C57BL/6 | J:76657 | View | ||||
| Parkinson's disease 1 | Tg(Prnp-SNCA*A53T)83Vle/Tg(Prnp-SNCA*A53T)83Vle | involves: C3H * C57BL/6 | J:76657 | View | ||||
| Parkinson's disease 1 | Tg(Prnp-SNCA*A53T)AAub/? | involves: FVB/N | J:216589 | View | ||||
| Parkinson's disease 1 | Tg(Prnp-SNCA*A53T)AAub/Tg(Prnp-SNCA*A53T)AAub | involves: FVB/N | J:181820, J:185489 | View | ||||
| Parkinson's disease 1 | Tg(SNCA)ARyot/0 | C57BL/6J-Tg(SNCA)ARyot | J:185434 | View | ||||
| Parkinson's disease 1 | Tg(SNCA*E46K)3Elan/? | involves: C57BL/6 * SJL | J:200740 | View | ||||
| Parkinson's disease 1 | Tg(Snca-SNCA)#Galt/? | involves: C57BL/6 * DBA/2 | J:199939 | View | ||||
| Parkinson's disease 1 | Tg(Th-SNCA*)1702Yosh/0 | involves: C3H * C57BL/6J | J:125149 | View | ||||
| Parkinson's disease 1 | Tg(Thy1-SNCA)61Ema/0 | involves: C57BL/6 * DBA/2 | J:137490 | View | ||||
| Parkinson's disease 1 | Tg(Thy1-SNCA*)#Ztzh/0 | involves: C57BL/6J | J:313970 | View | ||||
| Parkinson's disease 1 | Tg(Thy1-SNCA*A30P)18Pjk/Tg(Thy1-SNCA*A30P)18Pjk | involves: C57BL/6 | J:80181 | View | ||||
| Parkinson's disease 1 | Tg(THY1-SNCA*A53T)M53Sud/0 | B6.Cg-Tg(THY1-SNCA*A53T)M53Sud/J | J:212732 | View | ||||
| Parkinson's disease 1 | Tg(Thy1-SNCA*E57K)16Ema/0 | involves: C57BL/6 * DBA/2 | J:236596 | View | ||||
| Parkinson's disease 8 | Tg(PDGFB-LRRK2*G2019S)32Hlw/? | FVB/N-Tg(PDGFB-LRRK2*G2019S)32Hlw | J:204793 | View | ||||
| Parkinson's disease 8 | Tg(PDGFB-LRRK2*R1441C)31Hlw/0 | FVB/N-Tg(PDGFB-LRRK2*R1441C)31Hlw | J:229559 | View | ||||
| Additional Complex Models | Parkinson's disease 1 | 2310039L15RikTg(Prnp-SNCA*A53T)23Mkle/2310039L15Rik+ | involves: C3H/HeJ * C57BL/6J | J:77344 | View | |||
| Parkinson's disease 1 |
Gt(ROSA)26Sortm2(SNCA*119)Djmo/Gt(ROSA)26Sortm2(SNCA*119)Djmo 7630403G23RikTg(Th-cre)1Tmd/7630403G23Rik+ |
involves: 129 * C57BL/6 | J:150777 | View | ||||
| Parkinson's disease 1 |
Gt(ROSA)26Sortm2(SNCA*119)Djmo/Gt(ROSA)26Sortm2(SNCA*119)Djmo 7630403G23RikTg(Th-cre)1Tmd/7630403G23Rik+ |
involves: 129 * C57BL/6 * SJL | J:150777 | View | ||||
| Parkinson's disease 8 | Khdrbs2Tg(LRRK2*R1441G)135Cjli/Khdrbs2+ | FVB-Khdrbs2Tg(LRRK2*R1441G)135Cjli | J:149135 | View | ||||
| Parkinson's disease 8 | Khdrbs2Tg(LRRK2*R1441G)135Cjli/Khdrbs2+ | FVB/N-Khdrbs2Tg(LRRK2*R1441G)135Cjli/J | J:204940 | View | ||||