Excel File Text File All mouse models of bone development disease with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      acheiropody Lmbr1tm1Kng/Lmbr1tm1Kng involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J J:72166 View
achondrogenesis type IA Tg(EIIa-cre)C5379Lmgd/?
Trip11tm1.2Psmi/Trip11tm1.2Psmi		 involves: 129/Sv * C57BL/6 * FVB/N J:253969 View
achondrogenesis type IA Trip11m1Mawa/Trip11m1Mawa C57BL/6J-Trip11m1Mawa J:163656 View
achondrogenesis type IA Trip11tm1.1Psmi/Trip11tm1.2Psmi
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/?
Tg(Col2a1-cre)1Bhr/?		 involves: 129/Sv * C57BL/6 * SJL/J J:253969 View
achondrogenesis type II Col2a1tm1Prc/Col2a1tm1Prc involves: 129 J:117910 View
achondroplasia Fgfr3tm1.1(FGFR3*)Ytc/Fgfr3+ involves: 129 J:287271 View
achondroplasia Fgfr3tm1.1(FGFR3*)Ytc/Fgfr3tm1.1(FGFR3*)Ytc involves: 129 J:287271 View
achondroplasia Fgfr3tm1Cxd/Fgfr3tm1Cxd involves: 129S6/SvEvTac * NIH Black Swiss J:52438 View
achondroplasia Fgfr3tm1Llm/Fgfr3+ involves: 129S2/SvPas J:203653 View
achondroplasia Fgfr3tm2Wei/Fgfr3+ involves: 129S1/Sv * 129X1/SvJ * MF1 J:54829 View
achondroplasia Fgfr3tm3.1Cxd/Fgfr3+ involves: 129S6/SvEvTac J:69849 View
achondroplasia Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd involves: 129S6/SvEvTac J:69849 View
achondroplasia Fgfr3tm5.1Cxd/Fgfr3+ involves: 129S6/SvEvTac J:67780 View
achondroplasia Tg(Col2a1-Fgfr3/GH)BDor/0 FVB/N-Tg(Col2a1-Fgfr3/GH)BDor J:50292 View
acrocephalosyndactylia Fgfr2tm1Ewj/Fgfr2+
Tg(EIIa-cre)C5379Lmgd/0		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N J:101174, J:156940 View
acrocephalosyndactylia Fgfr2tm2.3Dsn/Fgfr2+ involves: 129 * C57BL/6 * FVB/N J:72517 View
acrocephalosyndactylia Fgfr2tm2Cxd/Fgfr2+
Tg(EIIa-cre)C5379Lmgd/0		 involves: 129S6/SvEvTac * C57BL/6J * FVB/N J:228708 View
acrocephalosyndactylia Fgfr2tm2Cxd/Fgfr2+
Tg(EIIa-cre)C5379Lmgd/0		 involves: 129S6/SvEvTac * FVB/N J:101385 View
acrocephalosyndactylia Fgfr2tm2Ewj/Fgfr2+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J J:156940 View
acrocephalosyndactylia Fgfr2tm2Ewj/Fgfr2+
Tg(EIIa-cre)C5379Lmgd/0		 B6.Cg-Fgfr2tm2Ewj Tg(EIIa-cre)C5379Lmgd J:158773 View
acrocephalosyndactylia Fgfr2tm3.1Cxd/Fgfr2+ involves: 129S6/SvEvTac * FVB/N J:283626 View
acrocephalosyndactylia Fgfr2tm3Cxd/Fgfr2+
Tg(Col2a1-cre)1Xya/0		 involves: 129S6/SvEvTac * C57BL/6J J:286452 View
acrodysostosis Prkar1atm1.1Geno/Prkar1a+ involves: C57BL/6J J:303060 View
acromesomelic dysplasia, Grebe type Gdf5Bp-5J/Gdf5+ C57BL/6J-Gdf5Bp-5J/GrsrJ J:200816 View
acromesomelic dysplasia, Grebe type Gdf5bp-J/Gdf5bp-J
Gdf6tm1Kng/Gdf6tm1Kng		 involves: 129S1/Sv * 129X1/SvJ * A/J * C57BL/6J J:83132 View
acromesomelic dysplasia, Hunter-Thompson type Gdf5Bp-5J/Gdf5+ C57BL/6J-Gdf5Bp-5J/GrsrJ J:200816 View
acromesomelic dysplasia, Maroteaux type Npr2pwe/Npr2pwe involves: C3H/HeJ * C57BL/6 * NAW/WI J:188839 View
acromesomelic dysplasia, Maroteaux type Npr2slw/Npr2slw involves: C57BL/6 * DDY J:129973 View
asphyxiating thoracic dystrophy 2 Ift80Gt(AN0245)Wtsi/Ift80Gt(AN0245)Wtsi involves: 129P2/OlaHsd J:169236 View
asphyxiating thoracic dystrophy 3 Dync2h1b2b414Clo/Dync2h1b2b414Clo C57BL/6J-Dync2h1b2b414Clo J:175213 View
brachydactyly type A1 Ihhtm1.1Dcha/Ihhtm1.1Dcha either: (involves: 129S/SvEv * FVB/N) or (involves: 129S/SvEv * FVB/N * ICR) J:147878 View
brachydactyly type A1C Gdf5Bp-5J/Gdf5+ C57BL/6J-Gdf5Bp-5J/GrsrJ J:200816 View
brachydactyly type A2 Gdf5Bp-5J/Gdf5+ C57BL/6J-Gdf5Bp-5J/GrsrJ J:200816 View
brachydactyly type C Gdf5Bp-5J/Gdf5+ C57BL/6J-Gdf5Bp-5J/GrsrJ J:200816 View
campomelic dysplasia Sox9Bbfc/Sox9+ C57BL/6J-Sox9Bbfc/GrsrJ J:223062 View
campomelic dysplasia Sox9tm1.1Gsr/Sox9+ involves: 129P2/OlaHsd * C57BL/6 J:75124 View
campomelic dysplasia Sox9tm1.2Ksec/Sox9+ involves: 129S/SvEv * C57BL/6 * FVB/N J:332093 View
campomelic dysplasia Sox9tm1Crm/Sox9+ involves: 129S7/SvEvBrd * C57BL/6 * CD-1 J:69875 View
campomelic dysplasia Sox9tm1Gsr/Sox9+
Tg(Pdx1-cre)6Cvw/0		 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA * FVB/N J:141017 View
campomelic dysplasia Sox9tm2Crm/Sox9+
Tg(Col2a1-cre)1Bhr/0		 involves: 129S7/SvEvBrd * C57BL/6 * SJL J:79879 View
campomelic dysplasia Sox9tm2Crm/Sox9+
Tg(Prrx1-cre)1Cjt/0		 involves: 129S7/SvEvBrd * C57BL/6J * SJL/J J:79879 View
campomelic dysplasia Sox9tm2Crm/Sox9tm2Crm
Tg(Col2a1-cre)1Bhr/0		 involves: 129S7/SvEvBrd * C57BL/6 * SJL J:79879 View
campomelic dysplasia Sox9tm2Crm/Sox9tm2Crm
Tg(Prrx1-cre)1Cjt/0		 involves: 129S7/SvEvBrd * C57BL/6J * SJL/J J:79879 View
Carpenter syndrome Megf8b2b288Clo/Megf8b2b288Clo C57BL/6J-Megf8b2b288Clo J:175213 View
Carpenter syndrome Megf8b2b1702.2Clo/Megf8b2b1702.2Clo C57BL/6J-Megf8b2b1702.2Clo J:175213 View
chondrodysplasia with joint dislocations gPAPP type Bpnt2tm1.2Aros/Bpnt2tm1.2Aros B6(SJL)-Bpnt2tm1.2Aros J:273179 View
cleidocranial dysplasia Runx2tm1Jals/Runx2tm1Jals involves: 129S7/SvEvBrd * C57BL/6 J:143532 View
cleidocranial dysplasia Runx2tm1Kish/Runx2+ involves: 129P2/OlaHsd * C57BL/6 J:40783 View
cleidocranial dysplasia Runx2tm1Kish/Runx2tm1Kish involves: 129P2/OlaHsd * C57BL/6 J:40783, J:53069, J:54095 View
cleidocranial dysplasia Runx2tm1Mjo/Runx2+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:40784, J:53868 View
clubfoot Pitx1tm1Rsd/Pitx1+ involves: 129S1/Sv * 129X1/SvJ J:175799 View
craniosynostosis Tg(CMV-Msx2*P7H)1Rem/0 involves: C57BL/6 * CBA/J J:26513 View
craniosynostosis Tg(Msx2)1Rem/0 involves: C57BL/6 * CBA/J J:26513 View
craniosynostosis Tg(Timp1-Msx2*P7H)1Rem/0 involves: C57BL/6 * CBA/J J:26513 View
Crouzon syndrome Fgfr2m1Sgg/Fgfr2+ involves: C3H/HeJ * C57BL/6J J:160674 View
Crouzon syndrome Fgfr2m1Sgg/Fgfr2m1Sgg involves: C3H/HeJ * C57BL/6J J:160674 View
Crouzon syndrome Fgfr2tm1Schl/Fgfr2+ involves: 129S1/Sv J:118299 View
Crouzon syndrome Fgfr2tm4Lni/Fgfr2+ Not Specified J:92433, J:235329 View
Desbuquois dysplasia Cant1tm1.1Aros/Cant1tm1.1Aros involves: 129 * C57BL/6J J:282272 View
Desbuquois dysplasia Cant1tm1.2Aros/Cant1tm1.2Aros involves: 129 * C57BL/6J J:282272 View
diastrophic dysplasia Slc26a2tm1Aros/Slc26a2tm1Aros involves: 129S7/SvEvBrd * C57BL/6J J:97104 View
fibular hypoplasia and complex brachydactyly Gdf5Bp-5J/Gdf5+ C57BL/6J-Gdf5Bp-5J/GrsrJ J:200816 View
Fuhrmann syndrome Wnt7apx-2J/Wnt7apx-2J B6;C3Fe-Wnt7apx-2J/GrsrJ J:188478 View
Fuhrmann syndrome Wnt7apx-J/Wnt7apx-J C57BL/6J-Wnt7apx-J/GrsrJ J:188477 View
geleophysic dysplasia 1 Adamtsl2tm1c(KOMP)Wtsi/Adamtsl2tm1c(KOMP)Wtsi
Tg(Prrx1-cre)1Cjt/0		 B6.Cg-Adamtsl2tm1c(KOMP)Wtsi Tg(Prrx1-cre)1Cjt J:280264 View
gnathodiaphyseal dysplasia Ano5em1Huyi/Ano5em1Huyi C57BL/6N-Ano5em1Huyi J:294237 View
gnathodiaphyseal dysplasia Ano5em2Huyi/Ano5em2Huyi C57BL/6-Ano5em2Huyi J:336715 View
Greig cephalopolysyndactyly syndrome Gli3Xt-J/Gli3Xt-J involves: C3H * CD-1 J:4086 View
hypertrichotic osteochondrodysplasia Cantu type Abcc9em1Nich/Abcc9+ involves: C57BL/6J * CBA/J J:281903 View
hypertrichotic osteochondrodysplasia Cantu type Abcc9em1Nich/Abcc9em1Nich involves: C57BL/6J * CBA/J J:281903 View
hypertrichotic osteochondrodysplasia Cantu type Abcc9em3Nich/Abcc9+ B6.Cg-Abcc9em3Nich J:308986 View
hypertrichotic osteochondrodysplasia Cantu type Abcc9em3Nich/Abcc9em3Nich B6.Cg-Abcc9em3Nich J:308986 View
hypochondroplasia Fgfr3tm3.1Llm/Fgfr3+ involves: C57BL/6N J:338859 View
microcephalic osteodysplastic primordial dwarfism type II PcntGt(RRU388)Byg/PcntGt(RRU388)Byg B6.129P2-PcntGt(RRU388)Byg J:226309 View
Muenke Syndrome Fgfr3tm1.1Aomw/Fgfr3+ 129S6.129P2-Fgfr3tm1.1Aomw J:144356 View
Muenke Syndrome Fgfr3tm1.1Aomw/Fgfr3+ B6.129P2-Fgfr3tm1.1Aomw J:144356 View
Muenke Syndrome Fgfr3tm1.1Aomw/Fgfr3+ CBACa.129P2-Fgfr3tm1.1Aomw J:144356 View
Muenke Syndrome Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw 129S6.129P2-Fgfr3tm1.1Aomw J:144356 View
Muenke Syndrome Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw B6.129P2-Fgfr3tm1.1Aomw J:144356 View
Muenke Syndrome Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw CBACa.129P2-Fgfr3tm1.1Aomw J:144356 View
multiple epiphyseal dysplasia 5 Matn3tm1Mbri/Matn3tm1Mbri involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:125104 View
osteogenesis imperfecta Col1a1m1Btlr/Col1a1m1Btlr C57BL/6J-Col1a1m1Btlr J:253622 View
osteogenesis imperfecta Col1a2oim/Col1a2+ B6C3Fe a/a-Col1a2oim/J J:38013 View
osteogenesis imperfecta Col1a2tm1.1Mcbr/Col1a2+ (A/J x B6.129-Col1a2tm1.1Mcbr)F1 J:178743 View
osteogenesis imperfecta Col1a2tm1.1Mcbr/Col1a2+ (BALB/cByJ x B6.129-Col1a2tm1.1Mcbr)F1 J:178743 View
osteogenesis imperfecta Col1a2tm1.1Mcbr/Col1a2+ (C3H/HeJ x B6.129-Col1a2tm1.1Mcbr)F1 J:178743 View
osteogenesis imperfecta Col1a2tm1.1Mcbr/Col1a2+ (FVB/NJ x B6.129-Col1a2tm1.1Mcbr)F1 J:178743 View
osteogenesis imperfecta type 1 Col1a1Mov13/Col1a1+ involves: C57BL/6 J:107045 View
osteogenesis imperfecta type 2 Col1a1Aga2/Col1a1+ involves: C3HeB/FeJ * C57BL/6J J:129569 View
osteogenesis imperfecta type 2 Col1a1tm1Jcm/Col1a1+ either: (involves: 129X1/SvJ * C3H/HeJ) or (involves: 129X1/SvJ * CD-1) J:59168 View
osteogenesis imperfecta type 3 Col1a1Aga2/Col1a1+ C3HeB/FeJ-Col1a1Aga2 J:185988 View
osteogenesis imperfecta type 3 Col1a2oim/Col1a2oim B6C3Fe a/a-Col1a2oim/J J:38013 View
osteogenesis imperfecta type 3 Col1a2oim/Col1a2oim involves: C3H/HeJ * C57BL/6JLe J:4348 View
osteogenesis imperfecta type 4 Col1a1M1Jrt/Col1a1+ involves: C3H/HeJ * C57BL/6J * FVB/NJ J:216423 View
osteogenesis imperfecta type 4 Col1a1M1Jrt/Col1a1+ involves: C57BL/6 * FVB/N J:228439 View
osteogenesis imperfecta type 4 Col1a1tm1.1Jcm/Col1a1+ either: (involves: 129X1/SvJ * C3H/HeJ) or (involves: 129X1/SvJ * CD-1) J:59168 View
osteogenesis imperfecta type 5 Tg(Col1a1-Ifitm5*)1Brle/0 involves: FVB/N J:233366 View
osteogenesis imperfecta type 6 Serpinf1tm1Craw/Serpinf1tm1Craw Not Specified J:230409 View
osteogenesis imperfecta type 7 Crtaptm1Brle/Crtaptm1Brle involves: 129S7/SvEvBrd J:116096 View
osteogenesis imperfecta type 8 P3h1tm1Dgen/P3h1tm1Dgen involves: C57BL/6 J:163884 View
osteogenesis imperfecta type 9 PpibGt(RST139)Byg/PpibGt(RST139)Byg involves: 129P2/OlaHsd * C57BL/6 J:226318 View
osteogenesis imperfecta type 9 Ppibtm1.1Rjb/Ppibtm1.1Rjb Not Specified J:161748 View
osteogenesis imperfecta type 10 Serpinh1tm2Kzn/Serpinh1tm2Kzn
Tg(Col2a1-cre)1Bhr/0		 involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL J:197791 View
otospondylomegaepiphyseal dysplasia, autosomal recessive Col11a2tm1Mne/Col11a2tm1Mne FVB.129-Col11a2tm1Mne J:71948 View
Pfeiffer syndrome Fgfr1tm1Led/Fgfr1tm1Led involves: 129S4/SvJae * NIH Black Swiss J:22118 View
Pfeiffer syndrome Fgfr1tm2.1Cxd/Fgfr1+ D2.129S6(Cg)-Fgfr1tm2.1Cxd J:228708 View
Pfeiffer syndrome Fgfr2tm2.3Dsn/Fgfr2+ involves: 129 * C57BL/6 * FVB/N J:72517 View
progressive pseudorheumatoid arthropathy of childhood Ccn6tm1(cre)Mawa/Ccn6tm1(cre)Mawa involves: 129S4/SvJae * C57BL/6 J:201718 View
progressive pseudorheumatoid arthropathy of childhood Ccn6tm2Mawa/Ccn6tm2Mawa 129S/SvEv-Ccn6tm2Mawa J:94500 View
progressive pseudorheumatoid arthropathy of childhood Ccn6tm2Mawa/Ccn6tm2Mawa involves: 129S/SvEv * C57BL/6 J:201718 View
pseudoachondroplasia Comptm1Mbri/Comptm1Mbri involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:125086 View
pseudoachondroplasia Comptm2.1Mbri/Comptm2.1Mbri involves: 129S1/Sv * 129X1/SvJ J:206511 View
Saethre-Chotzen syndrome Msx2tm1Rilm/Msx2+
Twist1tm1Bhr/Twist1+		 involves: 129S4/SvJae * 129S7/SvEvBrd * BALB/c * C57BL/6 J:87044 View
Saethre-Chotzen syndrome Twist1Pas/Twist1+ involves: C57BL/6 * PDT/Pas J:86815 View
Saethre-Chotzen syndrome Twist1Pas/Twist1Pas involves: C57BL/6 * PDT/Pas J:86815 View
Saethre-Chotzen syndrome Twist1Pde/Twist1+ involves: 129S1/Sv * C57BL/6J J:69450 View
Saethre-Chotzen syndrome Twist1Pde/Twist1Pde involves: 129S1/Sv * C57BL/6J J:69450 View
Saethre-Chotzen syndrome Twist1tm1Bhr/Twist1+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J J:79294 View
Saethre-Chotzen syndrome Twist1tm1Bhr/Twist1+ involves: 129S7/SvEvBrd * C57BL/6 J:44379 View
Saethre-Chotzen syndrome Twist1tm1Bhr/Twist1tm1Bhr involves: 129S7/SvEvBrd * C57BL/6 J:44379 View
Schimke immuno-osseous dysplasia Smarcal1tm1.1Cfbo/Smarcal1tm1.1Cfbo either: B6.129-Smarcal1tm1.1Cfbo or (involves: 129 * C57BL/6) J:183899 View
Schmid metaphyseal chondrodysplasia Col10a1tm1.1Rpbh/Col10a1tm1.1Rpbh involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:154052 View
Schmid metaphyseal chondrodysplasia Col10a1tm2.1Rpbh/Col10a1+ involves: C57BL/6NTac J:267200 View
Schmid metaphyseal chondrodysplasia Col10a1tm2.1Rpbh/Col10a1tm2.1Rpbh involves: C57BL/6NTac J:267200 View
schneckenbecken dysplasia Slc35d1tm1Hko/Slc35d1tm1Hko involves: 129S1/Sv * 129X1/SvJ J:130304 View
short-rib thoracic dysplasia 7 with or without polydactyly Wdr35yeti/Wdr35yeti Not Specified J:171617 View
short-rib thoracic dysplasia 9 with or without polydactyly Ift140b2b1283Clo/Ift140b2b1283Clo C57BL/6J-Ift140b2b1283Clo J:175213 View
Silverman-Handmaker type dyssegmental dysplasia Hspg2tm1Nid/Hspg2tm1Nid involves: 129X1/SvJ * C57BL/6 J:74542 View
Silverman-Handmaker type dyssegmental dysplasia Hspg2tm1Ref/Hspg2tm1Ref involves: 129S1/Sv * 129X1/SvJ J:84739 View
Smith-McCort dysplasia 2 Rab33bem1Rmr/Rab33b+ involves: C57BL/6 J:338833 View
Smith-McCort dysplasia 2 Rab33bem1Rmr/Rab33bem1Rmr involves: C57BL/6 J:338833 View
split hand-foot malformation 1 Del(6Dlx6-Dlx5)1Tlu/Del(6Dlx6-Dlx5)1Tlu Not Specified J:76480 View
split hand-foot malformation 1 Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi Not Specified J:77244 View
spondylocarpotarsal synostosis syndrome FlnbGt(RRF239)Byg/FlnbGt(RRF239)Byg involves: 129P2/OlaHsd * C57BL/6 J:132026 View
spondylocarpotarsal synostosis syndrome FlnbGt(XD076)Byg/FlnbGt(XD076)Byg involves: 129P2/OlaHsd * C57BL/6 J:134094 View
spondyloepimetaphyseal dysplasia, Pakistani type Papss2bm/Papss2bm LDJ/Le J:5109 View
spondyloepiphyseal dysplasia congenita Col2a1Lpk/Col2a1+ C.B6(C3)-Col2a1Lpk J:187141 View
spondyloepiphyseal dysplasia congenita Col2a1Lpk/Col2a1+ involves: C3H/HeH * C57BL/6J J:187141 View
spondyloepiphyseal dysplasia congenita Col2a1M2J/Col2a1+ B6;C3Fe-Col2a1M2J/GrsrJ J:222308 View
spondyloepiphyseal dysplasia congenita Col2a1M3J/Col2a1+ B6(Cg)-Col2a1M3J/GrsrJ J:222308 View
spondyloepiphyseal dysplasia congenita Col2a1sedc/Col2a1sedc involves: C57BL/6J J:85735 View
spondyloepiphyseal dysplasia congenita Col2a1tm1Prc/Col2a1tm1Prc involves: 129/Sv * C57BL/6 J:30041 View
spondyloepiphyseal dysplasia congenita Tg(Col2a1*R789C)#Waho/0 involves: C57BL/6 * DBA/2 J:112540 View
thanatophoric dysplasia Fgfr3tm1Llm/Fgfr3+ involves: 129S2/SvPas * C57BL/6J J:147208 View
thanatophoric dysplasia Fgfr3tm4.1Cxd/Fgfr3+ involves: 129S6/SvEvTac * NIH Black Swiss J:63198 View
thanatophoric dysplasia Fgfr3tm4Cxd/Fgfr3+
Tg(Col2a1-cre)1Bhr/0		 involves: 129S6/SvEvTac * C57BL/6 * NIH Black Swiss * SJL J:63198 View
thanatophoric dysplasia Fgfr3tm5.1Cxd/Fgfr3+ involves: 129S6/SvEvTac J:67780 View
      achondroplasia Acancmd/Acancmd involves: STOCK T tlow Itpr3tf J:5952, J:30795 View
achondroplasia Nppclbab/Nppclbab B6.PL-Nppclbab/GrsrJ J:122924 View
achondroplasia Nppctm1Yog/Nppctm1Yog either: 129X1/SvJ or (involves: 129 * C57BL/6J) J:75620 View
achondroplasia Npr2cn-2J/Npr2cn-2J B6;CBACa-Aw-J/A-Kcnj6wv/+ J:72465 View
achondroplasia Npr2cn-3J/Npr2cn-3J MRL/MpJ-Npr2cn-3J/GrsrJ J:170669 View
achondroplasia Npr2cn/Npr2cn involves: AKR/J J:26341 View
achondroplasia Pthlhtm1Hmk/Pthlhtm1Hmk either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6) J:16911 View
achondroplasia Spred2Gt(XB228)Byg/Spred2Gt(XB228)Byg involves: 129P2/OlaHsd * C57BL/6 J:100826 View
asphyxiating thoracic dystrophy Smarcad1tm1Gos/Smarcad1tm1Gos 129S2/SvPas-Smarcad1tm1Gos J:208500 View
asphyxiating thoracic dystrophy srt/srt Not Specified J:75360 View
asphyxiating thoracic dystrophy 1 Ift140cauli/Ift140cauli involves: C3H/HeH * C57BL/6JAnu J:220659 View
asphyxiating thoracic dystrophy 3 Ift80Gt(AN0245)Wtsi/Ift80Gt(AN0245)Wtsi involves: 129P2/OlaHsd J:169236 View
bone development disease Tg(Col11a2-Npr2*)28Keoz/0 involves: C57BL/6 J:189658 View
cleidocranial dysplasia Ccd/Ccd+ B10Rl.101-Ccd J:16170 View
cleidocranial dysplasia Ccd/Ccd+ involves: 101 * C3H J:14006 View
clubfoot cl/cl Not Specified J:294 View
clubfoot Dbf/Dbf+ involves: 101/H * C3H/HeH J:39106 View
clubfoot Fkbp8tm1Kei/Fkbp8tm1Kei involves: 129P2/OlaHsd * C57BL/6J J:132961 View
clubfoot Fras1bl/Fras1bl involves: 101/H * C3H/HeH J:83745 View
clubfoot Grip1eb/Grip1eb involves: hairless stock J:13412 View
clubfoot pma/pma involves: CF-1 J:8195 View
clubfoot Rettm1Kln/Rettm1Kln
Tg(Nes-cre)1Kln/0		 involves: 129/Sv * BALB/c * C57BL/6 * CBA/J * SJL J:110955 View
clubfoot skc3/skc3 involves: C57BL/6J J:85113 View
clubfoot Tcirg1oc/Tcirg1oc C57BL/6J-Vps33abf J:28464 View
clubfoot vsd/vsd C57BL/6J-vsd J:94456 View
craniosynostosis Axin2tm1Wbm/Axin2tm1Wbm involves: 129P2/OlaHsd * C57BL/6 J:98523 View
Crouzon syndrome Bey/Bey+ 129S/SvEv-Bey J:47965 View
dysostosis Kif3atm2Gsn/Kif3atm2Gsn
H2az2Tg(Wnt1-cre)11Rth/H2az2+		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J J:158523 View
hypertrichotic osteochondrodysplasia Cantu type Kcnj8em1Nich/Kcnj8+ involves: C57BL/6J * CBA/J J:281903 View
hypochondrogenesis Tg(Col2a1*G574S)1Waho/0 involves: C57BL/6 * DBA/2 J:38204 View
Leri-Weill dyschondrosteosis Shox2tm1Ddu/Shox2tm1.1Ddu
Tg(Prrx1-cre)1Cjt/0		 involves: 129S2/SvPas * C57BL/6J * SJL/J J:107668 View
multiple epiphyseal dysplasia Comptm1Mbri/Comptm1Mbri involves: 129S1/Sv * 129X1/SvJ J:154984 View
multiple synostoses syndrome Fgf9tm1Zgwg/Fgf9+ involves: 129S1/Sv J:241783 View
multiple synostoses syndrome Fgf9tm1Zgwg/Fgf9tm1Zgwg involves: 129S1/Sv J:241783 View
multiple synostoses syndrome Gdf5Bp-5J/Gdf5+ C57BL/6J-Gdf5Bp-5J/GrsrJ J:200816 View
osteochondrodysplasia Atf2tm1Glm/Atf2tm1Glm involves: 129S2/SvPas J:30611 View
osteochondrodysplasia Cebpbtm1Kish/Cebpbtm1Kish involves: 129P2/OlaHsd J:237461 View
osteochondrodysplasia Mir140em1Tkob/Mir140+ C57BL/6-Mir140em1Tkob J:286036 View
osteochondrodysplasia Mir140em1Tkob/Mir140em1Tkob C57BL/6-Mir140em1Tkob J:286036 View
osteochondrodysplasia Nppclbab/Nppclbab B6.PL-Nppclbab/GrsrJ J:321139 View
osteochondrodysplasia Rnf146tm1.1Rtpl/Rnf146tm1.1Rtpl
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0		 involves: C57BL/6J * CD-1 J:244583 View
osteogenesis imperfecta Smad4tm2.1Cxd/Smad4tm2.1Cxd
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0		 involves: 129S6/SvEvTac * C57BL/6J * CD-1 J:211171 View
osteogenesis imperfecta Smpd3fro/Smpd3fro Not Specified J:100158 View
osteogenesis imperfecta type 2 Smpd3fro/Smpd3fro Not Specified J:3906 View
osteogenesis imperfecta type 3 Smpd3fro/Smpd3fro Not Specified J:3906 View
osteogenesis imperfecta type 5 SucoGt(KST050)Byg/SucoGt(KST050)Byg involves: 129P2/OlaHsd * C57BL/6 * CD-1 J:159823 View
Smith-McCort dysplasia DymGt(GTR1.3)1Rul/DymGt(GTR1.3)1Rul involves: 129 J:141099 View
split hand-foot malformation Map3k20em2Smun/Map3k20em2Smun involves: 129S6/SvEvTac * C57BL/6NCrl J:231477 View
split hand-foot malformation 1 Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi Not Specified J:77244 View
spondylocostal dysostosis Dll3tm1Rbe/Dll3tm1Rbe involves: 129P2/Ola * C57BL/6 J:75954 View
spondylocostal dysostosis Hes7M1Btlr/Hes7+ C57BL/6J-Hes7M1Btlr J:307652 View
spondylocostal dysostosis Ripply2tm1Asas/Ripply2tm1Asas involves: C57BL/6 * CBA J:122747 View
spondyloepimetaphyseal dysplasia Col2a1Rgsc413/Col2a1Rgsc413 involves: C57BL/6JJcl * DBA/2JJcl J:260538 View
spondyloepimetaphyseal dysplasia Col2a1Rgsc856/Col2a1Rgsc856 involves: C57BL/6JJcl * DBA/2JJcl J:171906 View
spondyloepiphyseal dysplasia congenita Hapln1tm1Nid/Hapln1tm1Nid involves: 129S1/Sv * 129X1/SvJ J:52575 View
syndactyly b2b1594Clo/b2b1594Clo C57BL/6J-b2b1594Clo J:175213 View
synpolydactyly Hoxd13spdh/Hoxd13spdh B6C3Fe a/a-Hoxd13spdh/J J:47974 View
synpolydactyly Hoxd13tm1Ddu/Hoxd13tm1Ddu either: (involves: 129S2/SvPas * 129/Sv) or (involves: 129S2/SvPas * C57BL/6) J:15507 View
synpolydactyly Hoxd13tm1Mrc/Hoxd13tm1Mrc involves: 129S7/SvEvBrd J:32603 View
thanatophoric dysplasia Hspg2tm1Nid/Hspg2tm1Nid involves: 129X1/SvJ * C57BL/6 J:67299 View
Weissenbacher-Zweymuller syndrome Acvr2atm1Zuk/Acvr2atm1Zuk either: 129 or (involves: 129S7/SvEvBrd * C57BL/6) J:23924 View
Weissenbacher-Zweymuller syndrome hpmd/hpmd Not Specified J:75360 View
Weissenbacher-Zweymuller syndrome Mapk1tm1Gela/Mapk1tm1Gela
H2az2Tg(Wnt1-cre)11Rth/H2az2+		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * CBA/J J:239772 View
Weissenbacher-Zweymuller syndrome Sox11tm1.1Gan/Sox11tm1.1Gan
Tg(EIIa-cre)C5379Lmgd/0		 involves: 129S6/SvEvTac * C57BL/6 * FVB/N J:232434 View
Weissenbacher-Zweymuller syndrome Tfrctm3.1Nca/Tfrctm3.1Nca
H2az2Tg(Wnt1-cre)11Rth/H2az2+		 involves: 129S4/SvJae * C57BL/6J * CBA/J J:316198 View
Transgenes and
Other Mutations		     achondroplasia Tg(FGFR3-G380R)7Aya/0 involves: BALB/c * C57BL/6 J:59887 View
achondroplasia Tg(FGFR3-G380R)7Aya/Tg(FGFR3-G380R)7Aya involves: BALB/c * C57BL/6 J:59887 View
craniosynostosis Tg(Nell1)1Ting/0 involves: C3H * C57BL/6 J:79106 View
osteogenesis imperfecta type 1 Tg(COL1A1)73Prc/0 involves: FVB/N J:146429 View
pseudoachondroplasia Tg(Col2a1-rtTA,tetO-COMP*)2Jath/0 C57BL/6-Tg(Col2a1-rtTA,tetO-COMP*)2Jath J:152756, J:233238 View
Additional
Complex
Models		     acrocephalosyndactylia Spry2tm1Ayos/Spry2tm1Ayos
Spry4tm1Ayos/Spry4tm1Ayos		 involves: 129 * C57BL/6J J:116506 View
brachydactyly type A1 ShhDsh/Shh+ B10Rl.Cg-ShhDsh J:97323 View
osteogenesis imperfecta Bmp1tm1.1Dgr/Bmp1tm1.1Dgr
Tll1tm2.1Dgr/Tll1tm2.1Dgr
Ndor1Tg(UBC-cre/ERT2)1Ejb/0		 involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6 * SJL J:210366 View
split hand-foot malformation 3 Fbxw4Dac-2J/Fbxw4+
mdac/mdac		 CBy.MRL-Fbxw4Dac-2J/J J:133888 View
split hand-foot malformation 3 Fbxw4Dac/Fbxw4+
mdac/mdac		 involves: SM/Ckc J:29220, J:133888 View
spondylocostal dysostosis Tbx6rv/Tbx6rv involves: C57BL/J * C57BL/6J J:8119 View
spondyloepiphyseal dysplasia congenita Gt(ROSA)26Sortm5(ACTB-tTA)Luo/Gt(ROSA)26Sor+
Tg(Col2a1-cre)1Bhr/0
Tg(tetO/CMV-Col2a1*R992C,-GFP)#Afe/0		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL J:216945 View
Weissenbacher-Zweymuller syndrome Ptprftm1Wjh/Ptprftm1Wjh
Ptprstm1Mtr/Ptprstm1Mtr		 B6.Cg-Ptprftm1Wjh Ptprstm1Mtr J:199299 View

       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      achondroplasia Fgfr3tm1Dor/Fgfr3tm1Dor involves: 129S6/SvEvTac * C57BL/6 J:32991 View
brachydactyly type B1 Ror2tm1Anec/Ror2+ B6.129S1-Ror2tm1Anec J:134490 View
multiple epiphyseal dysplasia Comptm1Aol/Comptm1Aol involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:76781 View
osteogenesis imperfecta type 5 Ifitm5em1Pmof/Ifitm5+ involves: CD-1 J:255349 View
pseudoachondroplasia Comptm1Aol/Comptm1Aol involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:76781 View
thanatophoric dysplasia Fgfr3tm1Cxd/Fgfr3tm1Cxd involves: 129S6/SvEvTac * NIH Black Swiss J:52438 View