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All mouse models of neural tube defect with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
neural tube defect |
Celsr1Crsh/Celsr1+ Vangl2Lp/Vangl2+ |
C3H.Cg-Vangl2Lp Celsr1Crsh | J:216413 | View | ||||
neural tube defect | Mthfd1ltm1b(EUCOMM)Wtsi/Mthfd1ltm1b(EUCOMM)Wtsi | involves: C57BL/6N * FVB/N | J:193285 | View | ||||
neural tube defect | Mthfrtm1Rzn/Mthfrtm1Rzn | involves: 129S1/Sv * 129X1/SvJ * BALB/c | J:67779 | View | ||||
neural tube defect |
ScribCrc/Scrib+ Vangl2Lp/Vangl2+ |
C3H.Cg-Vangl2Lp ScribCrc | J:216413 | View | ||||
neural tube defect |
Vangl1Gt(XL802)Byg/Vangl1+ Vangl2Lp/Vangl2+ |
involves: 129P2/OlaHsd * C57BL/6J * LPT/LeJ | J:132697 | View | ||||
neural tube defect | Vangl2Lp/Vangl2Lp | involves: CBA/Ca * LPT/Le | J:47700 | View | ||||
parietal foramina | Alx4Lst-2J/Alx4Lst-2J | C57BL/6J-Alx4Lst-2J/J | J:223288 | View | ||||
parietal foramina | Msx2tm1Rilm/Msx2tm1Rilm | either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6J) | J:61509 | View | ||||
neural tube defect | Lrp6Cd/Lrp6Cd | A-Lrp6Cd | J:58433, J:101423 | View | ||||
neural tube defect | Pax3Sp-1Wli/Pax3Sp-1Wli | involves: C57BL/6J * CBA/CaJ | J:196572 | View | ||||
spina bifida | Fkbp8Gt(OST287985)Lex/Fkbp8Gt(OST287985)Lex | involves: 129S5/SvEvBrd * C57BL/6 | J:132031 | View | ||||
Additional Complex Models | neural tube defect |
Celsr1Crsh/Celsr1+ ScribCrc/Scrib+ |
C3H.Cg-ScribCrc Celsr1Crsh | J:216413 | View | |||
neural tube defect |
Celsr1Scy/Celsr1+ ScribCrc/Scrib+ |
C3H.Cg-ScribCrc Celsr1Scy | J:216413 | View | ||||
neural tube defect |
Pax1un/Pax1+ Tcf3tm1Cmu/Tcf3tm1Cmu |
involves: 129P2/OlaHsd * C3H * C57BL/6 | J:103567 | View |
No similarity to the expected human disease phenotype was found.
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
NOT Models | neural tube defect | Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg | involves: 129P2/OlaHsd * C57BL/6J | J:132697 | View |