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All mouse models of polycystic kidney disease with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | autosomal dominant polycystic kidney disease |
Pkd2tm1.1Gwu/Pkd2tm1.1Gwu Tg(Vil1-cre)997Gum/0 |
involves: C57BL/6 * C57BL/6J * SJL | J:265516 | View | |||
| autosomal recessive polycystic kidney disease | Pkhd1tm1.1Ggg/Pkhd1tm1.1Ggg | involves: 129S/SvEv * 129S4/SvJae * C57BL/6 | J:125113 | View | ||||
| autosomal recessive polycystic kidney disease | Pkhd1tm1Cjwa/Pkhd1tm1Cjwa | involves: 129S6/SvEvTac * FVB/N | J:140302 | View | ||||
| autosomal recessive polycystic kidney disease | Pkhd1tm1Gwu/Pkhd1tm1Gwu | involves: C57BL/6 | J:167782 | View | ||||
| autosomal recessive polycystic kidney disease | Pkhd1tm1Gwu/Pkhd1tm1Gwu | Not Specified | J:143394 | View | ||||
| autosomal recessive polycystic kidney disease | Pkhd1tm1Sswi/Pkhd1tm1Sswi | B6.Cg-Pkhd1tm1Sswi | J:186064 | View | ||||
| autosomal recessive polycystic kidney disease | Pkhd1tm2Cjwa/Pkhd1tm2Cjwa | either: B6.129(Cg)-Pkhd1tm2Cjwa or C.129(Cg)-Pkhd1tm2Cjwa | J:187735 | View | ||||
| polycystic kidney disease 1 |
Gpsm1tm1.1Lajb/Gpsm1tm1.1Lajb Pkd1tm1.1Fqi/Pkd1tm1.1Fqi |
involves: 129S6/SvEvTac | J:193175 | View | ||||
| polycystic kidney disease 1 | Pkd1b2b1585Clo/Pkd1b2b1585Clo | C57BL/6J-Pkd1b2b1585Clo | J:175213 | View | ||||
| polycystic kidney disease 1 | Pkd1tm1.1Fqi/Pkd1tm1.1Fqi | involves: 129S6/SvEvTac | J:193175 | View | ||||
| polycystic kidney disease 1 | Pkd1tm1.1Pcha/Pkd1tm1.1Pcha | involves: 129S1/Sv * C57BL/6 | J:193544 | View | ||||
| polycystic kidney disease 1 |
Pkd1tm1.1Pcha/Pkd1tm2Som Tg(Cdh16-cre)91Igr/0 |
involves: 129 * 129S4/SvJae * C57BL/6 * ICR | J:244067 | View | ||||
| polycystic kidney disease 1 | Pkd1tm1Bdgz/Pkd1+ | involves: 129S1/Sv * 129X1/SvJ | J:130086 | View | ||||
| polycystic kidney disease 1 | Pkd1tm1Djmp/Pkd1tm1Djmp | involves: 129P2/OlaHsd * C57BL/6 | J:94582 | View | ||||
| polycystic kidney disease 1 | Pkd1tm1Ggg/Pkd1tm1Ggg | Not Specified | J:76062 | View | ||||
| polycystic kidney disease 1 |
Pkd1tm1Gztn/Pkd1tm1Gztn Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+ |
involves: 129S/Sv * 129S7/SvEvBrd * C57BL/6 | J:162080 | View | ||||
| polycystic kidney disease 1 | Pkd1tm1Jzh/Pkd1+ | either: (involves: 129S4/SvJae * C57BL/6) or (involves: 129S4/SvJae * BALB/c) | J:43193, J:52573, J:72627 | View | ||||
| polycystic kidney disease 1 | Pkd1tm1Jzh/Pkd1tm1Jzh | either: (involves: 129S4/SvJae * C57BL/6) or (involves: 129S4/SvJae * BALB/c) | J:43193, J:72627, J:81443 | View | ||||
| polycystic kidney disease 1 | Pkd1tm1Rsa/Pkd1+ | involves: 129S4/SvJaeSor | J:72238 | View | ||||
| polycystic kidney disease 1 | Pkd1tm1Shh/Pkd1tm1.1Pcha | involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 | J:193544 | View | ||||
| polycystic kidney disease 1 |
Pkd1tm1Som/Pkd1+ Tg(Pkd1*)39Mtru/0 |
involves: 129/Sv * C57BL/6J * CBA/J * SJL | J:198147 | View | ||||
| polycystic kidney disease 1 | Pkd1tm2.1Ggg/Pkd1tm2.1Ggg | involves: 129S4/SvJae * Black Swiss * C57BL/6 | J:103719 | View | ||||
| polycystic kidney disease 1 |
Pkd1tm2Ggg/Pkd1tm2Ggg Tg(Col1a1-cre)1Bek/0 |
involves: 129S4/SvJae * CD-1 | J:191967 | View | ||||
| polycystic kidney disease 1 |
Pkd1tm2Ggg/Pkd1tm2Ggg Tg(Hoxb7-cre)13Amc/0 |
involves: 129S4/SvJae * C57BL/6 | J:171619 | View | ||||
| polycystic kidney disease 1 |
Pkd1tm2Ggg/Pkd1tm2Ggg Tg(MMTV-cre)4Mam/0 |
involves: 129S4/SvJae * FVB | J:103719 | View | ||||
| polycystic kidney disease 1 |
Pkd1tm2Ggg/Pkd1tm2Ggg Tg(Nes-cre)Wme/0 |
involves: 129S4/SvJae * C57BL/6 * CBA | J:185855 | View | ||||
| polycystic kidney disease 1 | Pkd1tm2Jzh/Pkd1+ | either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6) | J:72627 | View | ||||
| polycystic kidney disease 1 | Pkd1tm2Jzh/Pkd1tm2Jzh | either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6) | J:72627 | View | ||||
| polycystic kidney disease 1 | Pkd1tm2Jzh/Pkd1tm2Jzh | involves: 129S4/SvJae * C57BL/6 | J:140012 | View | ||||
| polycystic kidney disease 1 |
Pkd1tm2Som/Pkd1tm2.1Som Tg(Cdh16-cre)91Igr/0 |
involves: C57BL/6 * ICR * SJL | J:135301 | View | ||||
| polycystic kidney disease 1 |
Pkd1tm2Som/Pkd1tm2Som Tg(Cdh16-cre)91Igr/0 |
involves: 129S4/SvJae * C57BL/6 * ICR | J:244067 | View | ||||
| polycystic kidney disease 1 | Pkd1tm3.1Jzh/Pkd1tm3.1Jzh | involves: 129P2/OlaHsd * C57BL/6 | J:140012 | View | ||||
| polycystic kidney disease 1 |
Pkd1tm3Jzh/Pkd1tm3Jzh Tg(Ggt1-cre)M3Egn/0 |
involves: 129P2/OlaHsd * C57BL/6 * SJL | J:140012 | View | ||||
| polycystic kidney disease 1 | Tg(Pkd1*)39Mtru/0 | involves: C57BL/6J * CBA/J | J:198147 | View | ||||
| polycystic kidney disease 2 | Pkd2tm1Dwo/Pkd2tm1Dwo | either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) | J:77401 | View | ||||
| polycystic kidney disease 2 | Pkd2tm1Som/Pkd2+ | involves: 129/Sv * C57BL/6J * SJL | J:47035 | View | ||||
| polycystic kidney disease 2 | Pkd2tm1Som/Pkd2tm1Som | involves: 129/Sv * C57BL/6J * SJL | J:47035 | View | ||||
| polycystic kidney disease 2 | Pkd2tm1Som/Pkd2tm2Som | involves: 129/Sv * C57BL/6J * SJL | J:47035 | View | ||||
| polycystic kidney disease 2 | Pkd2tm2Som/Pkd2+ | involves: 129/Sv * C57BL/6J * SJL | J:59314 | View | ||||
| polycystic kidney disease 2 | Pkd2tm2Som/Pkd2tm2Som | involves: 129/Sv * C57BL/6J * SJL | J:59314 | View | ||||
| polycystic kidney disease 2 |
Pkd2tm3Som/Pkd2tm3Som Tg(Pkhd1-cre)1Igr/0 |
involves: 129S4/SvJae * C57BL/6 | J:244067 | View | ||||
| polycystic kidney disease 4 | Pkhd1em1Mrug/Pkhd1+ | involves: C57BL/6J | J:281464 | View | ||||
| polycystic kidney disease 4 | Pkhd1em1Mrug/Pkhd1em1Mrug | involves: C57BL/6J | J:281464 | View | ||||
| | autosomal dominant polycystic kidney disease | Bicc1jcpk/Bicc1+ | involves: 101 * C3H * T STOCK | J:23047 | View | |||
| autosomal dominant polycystic kidney disease | Nphp3pcy/Nphp3pcy | either: D2.KK-Nphp3pcy or (involves: DBA/2Fg * DBA/2J * KK) | J:11399 | View | ||||
| autosomal dominant polycystic kidney disease | Nphp3pcy/Nphp3pcy | involves: KK | J:244067 | View | ||||
| autosomal dominant polycystic kidney disease | Nphp3pcy/Nphp3pcy | KK-Nphp3pcy | J:8302 | View | ||||
| autosomal dominant polycystic kidney disease | Tg(HBB-Myc)#Cos/0 | involves: C57BL/6J * CBA/J | J:45203 | View | ||||
| autosomal recessive polycystic kidney disease | Arl3Gt(OST263303)Lex/Arl3Gt(OST263303)Lex | involves: 129S5/SvEvBrd | J:107331 | View | ||||
| autosomal recessive polycystic kidney disease | Bicc1jcpk-bpk/Bicc1jcpk-bpk | BALB/c-Bicc1jcpk-bpk | J:13276, J:21554, J:36348 | View | ||||
| autosomal recessive polycystic kidney disease | Bicc1jcpk-bpk/Bicc1jcpk-bpk | involves: BALB/c * CAST/EiJ | J:36348 | View | ||||
| autosomal recessive polycystic kidney disease | Bicc1jcpk/Bicc1jcpk-bpk | involves: 101 * BALB/c * C3H * C57BL/6J * T STOCK | J:36348 | View | ||||
| autosomal recessive polycystic kidney disease | Bicc1jcpk/Bicc1jcpk | involves: 101 * C3H * C57BL/6J * T STOCK | J:36348 | View | ||||
| autosomal recessive polycystic kidney disease | Bicc1jcpk/Bicc1jcpk | involves: 101 * C3H * T STOCK | J:23047 | View | ||||
| autosomal recessive polycystic kidney disease | Bicc1tm1Emdr/Bicc1tm1Emdr | B6SJL-Bicc1tm1Emdr | J:121683 | View | ||||
| autosomal recessive polycystic kidney disease | Cys1cpk/Cys1cpk | B6(Cg)-Cys1cpk/J | J:6718, J:9290 | View | ||||
| autosomal recessive polycystic kidney disease | Cys1cpk/Cys1cpk | B6(Cg)-Cys1cpk/JUnc | J:7202 | View | ||||
| autosomal recessive polycystic kidney disease | Cys1cpk/Cys1cpk | C.B6(Cg)-Cys1cpk | J:99616 | View | ||||
| autosomal recessive polycystic kidney disease | Cys1cpk/Cys1cpk | D2J.B6(Cg)-Cys1cpk | J:99620 | View | ||||
| autosomal recessive polycystic kidney disease | Cys1cpk/Cys1cpk | involves: C57BL/6J * CD-1 | J:33739 | View | ||||
| autosomal recessive polycystic kidney disease | Dzip1lwarpy/Dzip1lwarpy | involves: C3H * C57BL/6 | J:249936 | View | ||||
| autosomal recessive polycystic kidney disease | Dzip1lwarpy/Dzip1lwarpy | involves: C57BL/6 * CD-1 | J:249936 | View | ||||
| autosomal recessive polycystic kidney disease | Ift88Tg737Rpw/Ift88Tg737Rpw | C3.FVB-Ift88Tg737Rpw | J:18508, J:73583 | View | ||||
| autosomal recessive polycystic kidney disease | Ift88Tg737Rpw/Ift88Tg737Rpw | FVB/N-Ift88Tg737Rpw | J:18508, J:37149, J:73583, J:95813 | View | ||||
| autosomal recessive polycystic kidney disease | Ift88Tg737Rpw/Ift88Tg737Rpw | involves: C3H * FVB/N | J:73583 | View | ||||
| autosomal recessive polycystic kidney disease | Ift88Tg737Rpw/Ift88Tg737Rpw | involves: FVB/N | J:65500, J:90990 | View | ||||
| autosomal recessive polycystic kidney disease | Nek1kat-2J/Nek1kat-2J | C57BL/6J-Nek1kat-2J/J | J:37799 | View | ||||
| autosomal recessive polycystic kidney disease | Nek1kat/Nek1kat | involves: C3HeB/FeJLe * C57BL/6J * RBF/Dn | J:37799 | View | ||||
| autosomal recessive polycystic kidney disease | Nek8jck/Nek8jck | involves: C57BL/6J | J:11885 | View | ||||
| autosomal recessive polycystic kidney disease | Pkd1m1Bei/Pkd1m1Bei | involves: A/J * FVB/N | J:75360 | View | ||||
| autosomal recessive polycystic kidney disease | Sclt1Tg(CAG-sb10)1Dla/Sclt1Tg(CAG-sb10)1Dla | FVB/N-Sclt1Tg(CAG-sb10)1Dla | J:243427 | View | ||||
| autosomal recessive polycystic kidney disease | Tg(Pkd1)26Mtru/0 | involves: C57BL/6J * CBA/J | J:157952 | View | ||||
| autosomal recessive polycystic kidney disease |
Tsc1tm1Djk/Tsc1tm1Djk Tg(Pax8-rtTA2S*M2)1Koes/0 Tg(tetO-cre)LC1Bjd/0 |
involves: 129S4/SvJae * BALB/c * C57BL/6 * DBA | J:140925 | View | ||||
| polycystic kidney disease |
Kif3atm1Gsn/Kif3atm2Gsn Tg(Cdh16-cre)91Igr/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * ICR | J:83293 | View | ||||
| polycystic kidney disease | Tg(Actb-Ptma)T12Clwu/Tg(Actb-Ptma)T12Clwu | involves: FVB/N | J:128557 | View | ||||
| polycystic kidney disease | Tulp3m1Kflj/Tulp3m1Kflj | involves: C57BL/6J * FVB/NJ | J:284006 | View | ||||
| polycystic kidney disease | Xylt2tm1Meh/Xylt2tm1Meh | involves: 129P2/OlaHsd | J:122291 | View | ||||
| Transgenes and Other Mutations | autosomal recessive polycystic kidney disease | T(2;10)67Gso/T(2;10)67Gso | involves: 101 * C3H * C3H/Rl * C57BL/RlGso * SEC/RlGso | J:75799 | View | |||
| polycystic kidney disease 2 | Tg(CAG-PKD2)#Hwl/? | involves: FVB/NJ | J:148377 | View | ||||
| Additional Complex Models | polycystic kidney disease | MitfTg(Tff3-Tmem207)2Tamo/Mitf+ | involves: C57BL/6 | J:244533 | View | |||
| polycystic kidney disease | MitfTg(Tff3-Tmem207)2Tamo/MitfTg(Tff3-Tmem207)2Tamo | involves: C57BL/6 | J:244533 | View | ||||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | autosomal recessive polycystic kidney disease | Pkhd1tm1Rbu/Pkhd1tm1Rbu | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:112509 | View | |||