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All mouse models of differentiated high-grade thyroid carcinoma with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
papillary thyroid carcinoma |
Braftm1Cpri/Braftm1Cpri Tg(TPO-cre)1Shk/0 |
involves: 129P2/OlaHsd * FVB/NCr | J:168249 | View | ||||
papillary thyroid carcinoma |
Braftm1Mmcm/Braf+ Tg(Tg-cre/ERT2)#Mmcm/0 |
involves: 129P2/OlaHsd | J:172205 | View | ||||
follicular thyroid carcinoma |
Prkar1atm1.2Lsk/Prkar1atm1.2Lsk Ptentm1.1Mwst/Ptentm1.1Mwst Tg(TPO-cre)1Shk/0 |
involves: 129S1/Sv * 129X1/SvJ * FVB/NCr | J:241066 | View | ||||
follicular thyroid carcinoma |
Prkar1atm1.2Lsk/Prkar1atm1.2Lsk Tg(TPO-cre)1Shk/0 |
involves: 129S1/Sv * 129X1/SvJ * FVB/NCr | J:241066 | View | ||||
follicular thyroid carcinoma |
Ptentm1Hwu/Pten+ Tg(Nkx2-1-cre)2Sand/0 |
B6.Cg-Ptentm1Hwu Tg(Nkx2-1-cre)2Sand | J:197590 | View | ||||
follicular thyroid carcinoma |
Ptentm2.1Ppp/Ptentm2.1Ppp Tg(TPO-cre)1Shk/0 |
129S1.Cg-Ptentm2.1Ppp Tg(TPO-cre)1Shk | J:165293 | View | ||||
follicular thyroid carcinoma | Thrbtm1.1Syc/Thrbtm1.1Syc | involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6 * C57BL/6J | J:92629 | View | ||||
follicular thyroid carcinoma | Thrbtm1Df/Thrbtm1.1Syc | involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6 * C57BL/6J | J:92629 | View | ||||
Transgenes and Other Mutations | follicular thyroid carcinoma | Tg(TG-NRAS*Q61K)#Msnt/0 | Not Specified | J:210016 | View | |||
papillary thyroid carcinoma |
Tg(tetO-BRAF*V600E)26Jaf/0 Tg(TG-rtTA)30Jaf/0 |
involves: FVB/N | J:184420 | View | ||||
papillary thyroid carcinoma | Tg(TG-BRAF*V600E)2Jaf/0 | FVB/N-Tg(TG-BRAF*V600E)2Jaf | J:98550, J:195921 | View | ||||
papillary thyroid carcinoma | Tg(TG-RET/CCDC6)42Cled/0 | involves: FVB/N | J:93679, J:55883 | View | ||||
papillary thyroid carcinoma | Tg(TG-RET/NCOA4)3209Rstn/0 | involves: C57BL/6 | J:51366 | View | ||||
papillary thyroid carcinoma | Tg(TG-TPR/NTRK1)5215Rstn/0 | involves: C3H * C57BL/6 | J:67120 | View |