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All mouse models of progeroid syndrome with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | progeria | LmnaDhe/Lmna+ | B6(D2)-LmnaDhe/TyGrsrJ | J:171665 | View | |||
| progeria | Lmnaem1Fenz/Lmna+ | C57BL/6-Lmnaem1Fenz | J:338760 | View | ||||
| progeria | Lmnatm1.1Bliu/Lmna+ | involves: C57BL/6 * FVB/N | J:287256 | View | ||||
| progeria | Lmnatm1.1Bliu/Lmnatm1.1Bliu | involves: C57BL/6 * FVB/N | J:287256 | View | ||||
| progeria | Lmnatm1.1Otin/Lmna+ | involves: 129P2/OlaHsd * C57BL/6 | J:211388 | View | ||||
| progeria | Lmnatm1.1Otin/Lmna+ | involves: 129P2/OlaHsd * C57BL/6NTac | J:261974 | View | ||||
| progeria |
Lmnatm1.1Otin/Lmna+ Nat10tm1a(KOMP)Wtsi/Nat10+ |
involves: 129P2/OlaHsd * C57BL/6NTac | J:261974 | View | ||||
| progeria | Lmnatm1.1Otin/Lmnatm1.1Otin | involves: 129P2/OlaHsd * C57BL/6 | J:177575, J:177632, J:211388 | View | ||||
| progeria | Lmnatm1.1Otin/Lmnatm1.1Otin | involves: 129P2/OlaHsd * C57BL/6NTac | J:261974 | View | ||||
| progeria |
Lmnatm1.1Otin/Lmnatm1.1Otin Nat10tm1a(KOMP)Wtsi/Nat10+ |
involves: 129P2/OlaHsd * C57BL/6NTac | J:261974 | View | ||||
| progeria |
Lmnatm1Bliu/Lmnatm1Bliu Tg(Tek-cre)1Ywa/0 |
involves: C57BL/6 * SJL | J:287256 | View | ||||
| progeria | Lmnatm1Lgf/Lmna+ | involves: 129P2/OlaHsd * C57BL/6 | J:113119 | View | ||||
| progeria | Lmnatm2Stw/Lmnatm2Stw | involves: 129S1/Sv | J:83382 | View | ||||
| progeria | Lmnatm12Lgf/Lmnatm12Lgf | involves: 129P2/OlaHsd * C57BL/6 | J:234711 | View | ||||
| Werner syndrome |
Terctm1Rdp/Terctm1Rdp Wrntm1Lgu/Wrntm1Lgu |
involves: 129/Sv * BALB/c * C57BL/6 * SLJ | J:91715 | View | ||||
| Werner syndrome | Wrntm1Led/Wrntm1Led | B6.129S6(BKSW)-Wrntm1Led | J:106446 | View | ||||
| | progeria | Sirt6tm1Fwa/Sirt6tm1Fwa | involves: 129S6/SvEvTac * 129X1/SvJ | J:112817 | View | |||
| progeria | Vcpip1em1Zlou/Vcpip1em1Zlou | C57BL/6NHsd-Vcpip1em1Zlou | J:297179 | View | ||||
| progeria | Zmpste24tm1Otin/Zmpste24tm1Otin | involves: 129P2/OlaHsd | J:164373 | View | ||||
| progeria | Zmpste24tm1Sgy/Zmpste24tm1Sgy | B6.129S4-Zmpste24tm1Sgy | J:106706 | View | ||||
| progeria | Zmpste24tm1Sgy/Zmpste24tm1Sgy | involves: 129S4/SvJae * C57BL/6 | J:95274 | View | ||||
| XFE progeroid syndrome | Ercc1tm1Jhjh/Ercc1tm1Jhjh | involves: 129P2/OlaHsd * C57BL/6 * FVB | J:117488 | View | ||||
| Transgenes and Other Mutations | progeria |
Tg(KRT5-tTA)1216Glk/0 Tg(tetO-LMNA*G608G,-EGFP)VF1-07Maer/0 |
involves: FVB/N | J:145312 | View | |||
| progeria | Tg(LMNA*G608G)HClns/? | C57BL/6-Tg(LMNA*G608G)HClns/J | J:107176 | View | ||||
| Werner syndrome | Tg(CAG-WRN*K577M)5025Wcl/0 | involves: C3H * C57BL/6J | J:95127 | View | ||||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | progeria | Lmnatm5Lgf/Lmnatm5Lgf | involves: 129P2/OlaHsd * C57BL/6 | J:160705 | View | |||
| progeria | Lmnatm8Lgf/Lmnatm8Lgf | involves: 129P2/OlaHsd | J:167229 | View | ||||