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All mouse models of sickle cell disease with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
 | sickle cell anemia | Spta1sph-ha/Spta1sph-ha | either: (B6.D1-Spta1sph-ha x WB.D1-Spta1sph-ha)F1 or (WB.D1-Spta1sph-ha x B6.D1-Spta1sph-ha)F1 | J:12830 | View | |||
 | sickle cell anemia |
Hbatm1(HBA)Tow/Hbatm1(HBA)Tow Hbbtm2(HBG1,HBB*)Tow/Hbbtm2(HBG1,HBB*)Tow |
Not Specified | J:134980 | View | |||
| sickle cell anemia |
Hbatm1(HBA)Tow/Hbatm1(HBA)Tow Hbbtm2(HBG1,HBB*)Tow/Hbbtm2(HBG1,HBB*)Tow Slc12a4Rbc10/Slc12a4+ |
involves: 129 * BALB/c * C57BL/6J | J:227339 | View | ||||
| sickle cell anemia |
Hbatm1Paz/Hbatm1Paz Hbbtm1Tow/Hbbtm1Tow Tg(HBA-HBBs)41Paz/? |
involves: 129S2/SvPas * 129S7/SvEvBrd * Black Swiss * C57BL/6 * DBA/2* FVB/N | J:44161 | View | ||||
| sickle cell anemia |
Hbbd3th/Hbb+ Tg(HBB-AR-HBA2,-HBB*)58Rub/0 Tg(LCR-HBA2,LCR-HBB)11Cos/0 |
involves: FVB/N * Swiss Webster | J:94190 | View | ||||
| sickle cell anemia |
Hbbd3th/Hbb+ Tg(LCR-HBA1,LCR-HBB*)1Tow/0 |
involves: C57BL/6 * DBA/2J * SJL | J:127701 | View | ||||
| sickle cell anemia |
Hbbd3th/Hbb+ Tg(LCR-HBA2,LCR-HBB*)1Cos/0 |
involves: C57BL/6J * CBA/J * DBA/2J | J:94193 | View | ||||
| sickle cell anemia |
Hbbd3th/Hbbd3th Tg(HBB-AR-HBA2,-HBB*)58Rub/0 Tg(LCR-HBA2,LCR-HBB)11Cos/0 |
involves: FVB/N * Swiss Webster | J:94190 | View | ||||