Excel File Text File All mouse models of combined immunodeficiency with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      adenosine deaminase deficiency Adatm1Mw/Adatm1Mw
Tg(PLADA)4118Rkmb/0		 involves: 129S7/SvEvBrd * C57BL/6 J:73418 View
DNA ligase IV deficiency Lig4tiny/Lig4tiny C57BL/6-Lig4tiny J:122725 View
DNA ligase IV deficiency Lig4tm2.1Fwa/Lig4tm2.1Fwa involves: 129S6/SvEvTac J:157574 View
immunodeficiency 15A Ikbkbem1Macc/Ikbkb+ involves: C57BL/6NCrl J:290616 View
immunodeficiency 15A Ikbkbem1Macc/Ikbkbem1Macc involves: C57BL/6NCrl J:290616 View
immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia Rac2em1Shl/Rac2+ involves: C57BL/6 J:276213 View
leukocyte adhesion deficiency 1 Itgb2tm1Bay/Itgb2tm1Bay involves: 129S7/SvEvBrd J:13599 View
leukocyte adhesion deficiency 1 Itgb2tm1Bay/Itgb2tm1Bay involves: 129S7/SvEvBrd * C57BL/6J J:13599 View
leukocyte adhesion deficiency 1 Itgb2tm2Bay/Itgb2tm2Bay involves: 129S7/SvEvBrd * C57BL/6J J:48542 View
leukocyte adhesion deficiency 3 Fermt3tm1Ref/Fermt3tm1Ref involves: 129S1/Sv * 129X1/SvJ J:146783 View
MHC class II deficiency Ciitatm1Ccum/Ciitatm1Ccum involves: 129S2/SvPas * C57BL/6J J:31601 View
MHC class II deficiency Ciitatm2Wrth/Ciitatm2Wrth involves: 129P2/OlaHsd * C57BL/6 J:92170 View
Omenn syndrome Rag2tm1Avla/Rag2tm1Avla involves: 129/Sv * C57BL/6 J:122108 View
purine nucleoside phosphorylase deficiency Pnpe/Pnpe C57BL/6J-Pnpe J:39328 View
purine nucleoside phosphorylase deficiency Pnpe/Pnpe involves: C3H/HeHa * C57BL/6J J:23354 View
purine nucleoside phosphorylase deficiency Pnpf/Pnpf C57BL/6J-Pnpf J:39328 View
purine nucleoside phosphorylase deficiency Pnpf/Pnpf involves: C3H/HeHa * C57BL/6J J:23354 View
purine nucleoside phosphorylase deficiency Pnpg/Pnpg involves: C57BL/6 * DBA/2J J:39328 View
severe combined immunodeficiency with sensitivity to ionizing radiation Dclre1ctm1Jsek/Dclre1ctm1Jsek involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:147864 View
severe combined immunodeficiency with sensitivity to ionizing radiation Dclre1ctm2Mcow/Dclre1ctm2Mcow involves: 129/Sv * C57BL/6 J:96535 View
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-positive Rag2tm1Fwa/Rag2tm1Fwa involves: 129S/SvEv * MF1 J:1935 View
T-cell immunodeficiency, congenital alopecia, and nail dystrophy Foxn1nu-2J/Foxn1nu-2J B6(SJL)-Foxn1nu-2J/GrsrJ J:222308 View
T-cell immunodeficiency, congenital alopecia, and nail dystrophy Foxn1nu-Y/Foxn1nu-Y 101/HY-Foxn1nu-Y J:29022 View
T-cell immunodeficiency, congenital alopecia, and nail dystrophy Foxn1nu/Foxn1nu Not Specified J:11959 View
T-cell immunodeficiency, congenital alopecia, and nail dystrophy Foxn1tm1Tbo/Foxn1tm1Tbo involves: 129S1/Sv J:33796 View
      combined immunodeficiency Copg1em1Geha/Copg1em1Geha involves: C57BL/6 J:345528 View
leukocyte adhesion deficiency 3 Rasgrp2tm1Amg/Rasgrp2tm1Amg Not Specified J:122618 View
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-positive Prkdcscid/Prkdcscid C.BKa-Prkdcscid J:6958 View
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive Coro1akoy/Coro1akoy C57BL/6-Coro1akoy J:141431 View
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive Coro1aptcd/Coro1aptcd B6.CTS-Coro1aptcd J:141431 View
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive Coro1aptcd/Coro1atm1Achn B6.Cg-Coro1aptcd Coro1atm1Achn J:141431 View
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive Coro1atm1Achn/Coro1atm1Achn B6.129X1-Coro1atm1Achn J:141431 View
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive Jak3tm1Ljb/Jak3tm1Ljb involves: 129S4/SvJae J:64861 View
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive Jak3tm1Tks/Jak3tm1Tks involves: 129P2/OlaHsd * C57BL/6 J:31231 View

       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      combined T cell and B cell immunodeficiency Il2rgtm1Cgn/Il2rgtm1Cgn involves: 129 * CB20 J:22521 View
combined T cell and B cell immunodeficiency Il2rgtm1Cgn/Y involves: 129 * CB20 J:22521 View
combined T cell and B cell immunodeficiency Il2rgtm1Sug/Y either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129S6/SvEvTac * C57BL/6) J:31167 View
immunodeficiency 24 Ctps1em1Slat/Ctps1em1Slat C57BL/6J-Ctps1em1Slat J:348981 View
Omenn syndrome Rag1tm1Jsek/Rag1tm1Jsek involves: 129S6/SvEvTac J:146912 View
X-linked severe combined immunodeficiency Il2rgtm1Cgn/Il2rgtm1Cgn involves: 129 * CB20 J:22521 View
X-linked severe combined immunodeficiency Il2rgtm1Cgn/Y involves: 129 * CB20 J:22521 View
X-linked severe combined immunodeficiency Il2rgtm1Sug/Y either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129S6/SvEvTac * C57BL/6) J:31167 View