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All mouse models of prostate cancer with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | prostate cancer | Acp3tm1Pivi/Acp3tm1Pivi | B6.Cg-Acp3tm1Pivi | J:207558 | View | |||
| prostate cancer |
Apctm1Tno/Apctm1Tno Tg(Pbsn-cre)4Prb/0 |
involves: 129S4/SvJae * C57BL/6 * C57BL/6J * DBA/2 | J:120308 | View | ||||
| prostate cancer |
Artm1Verh/Y Ptentm1Hwu/Ptentm1Hwu Tg(Pbsn-cre)4Prb/0 |
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * DBA/2 | J:172730 | View | ||||
| prostate cancer |
Braftm1Mmcm/Braftm1Mmcm Nkx3-1tm4(cre/ERT2)Mms/Nkx3-1+ Ptentm1Hwu/Pten+ |
involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac * C57BL/6 | J:191327 | View | ||||
| prostate cancer |
Gt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki/Gt(ROSA)26Sor+ Ptentm1Mro/Pten+ Tg(Pbsn-cre)4Prb/0 |
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N | J:184533 | View | ||||
| prostate cancer |
Gt(ROSA)26Sortm1(JAG1)Xin/Gt(ROSA)26Sor+ Ptentm1Hwu/Ptentm1Hwu Tg(Pbsn-cre)20Fwan/? |
involves: 129S4/SvJae * C57BL/6 * FVB/NCrl | J:238768 | View | ||||
| prostate cancer |
Gt(ROSA)26Sortm1(SPOP*F133V)Mrbn/Gt(ROSA)26Sor+ Ptentm2.1Ppp/Pten+ Tg(Pbsn-cre)4Prb/0 |
involves: 129S1/Sv * C57BL/6 * DBA/2 | J:239660 | View | ||||
| prostate cancer |
Gt(ROSA)26Sortm1(SPOP*F133V)Mrbn/Gt(ROSA)26Sor+ Ptentm2.1Ppp/Ptentm2.1Ppp Tg(Pbsn-cre)4Prb/0 |
involves: 129S1/Sv * C57BL/6 * DBA/2 | J:239660 | View | ||||
| prostate cancer |
Igs2tm1(CAG-Met)Zsu/Igs2+ Ptentm1Hwu/Ptentm1Hwu Tg(Pbsn-cre)4Prb/0 |
involves: 129 * C57BL/6 * DBA/2 * FVB/N | J:268934 | View | ||||
| prostate cancer |
Krastm4Tyj/Kras+ Ptentm1Hwu/Pten+ Tg(Pbsn-cre)4Prb/0 |
involves: 129S4/SvJae * C57BL/6 * DBA/2 | J:184935 | View | ||||
| prostate cancer |
Krastm4Tyj/Kras+ Ptentm1Hwu/Ptentm1Hwu Tg(Pbsn-cre)4Prb/0 |
involves: 129S4/SvJae * C57BL/6 * DBA/2 | J:184935 | View | ||||
| prostate cancer |
Nkx3-1tm1Mms/Nkx3-1+ Ptentm1Rps/Pten+ |
involves: 129S1/Sv * 129S1/SvImJ * C57BL/6J | J:75085 | View | ||||
| prostate cancer |
Nkx3-1tm1Mms/Nkx3-1tm1Mms Ptentm1Rps/Pten+ |
involves: 129S1/Sv * 129S1/SvImJ * C57BL/6J | J:75085 | View | ||||
| prostate cancer |
Ptentm1Hwu/Pten+ Tg(ARR2/Pbsn-FGF8)3Prb/0 Tg(Pbsn-cre)4Prb/0 |
involves: 129S4/SvJae * BALB/c * C57BL/6 * DBA/2 | J:106650 | View | ||||
| prostate cancer |
Ptentm1Hwu/Ptentm1Hwu Tg(CAG-MYC,-GFP*)#Rugg/0 Tg(Pbsn-cre)4Prb/0 |
involves: 129S4/SvJae * C57BL/6 * C57BL/6J * DBA/2 | J:261540 | View | ||||
| prostate cancer |
Ptentm1Hwu/Ptentm1Hwu Tg(Pbsn-cre)4Prb/0 |
involves: 129S4/SvJae * BALB/c * C57BL/6 * DBA/2 | J:93902 | View | ||||
| prostate cancer |
Ptentm1Hwu/Ptentm1Hwu Tg(Pbsn-cre)4Prb/0 |
involves: 129S4/SvJae * C57BL/6 * DBA/2 | J:172730, J:184935 | View | ||||
| prostate cancer |
Ptentm1Hwu/Ptentm1Hwu Tg(Pbsn-cre)20Fwan/? |
involves: 129S4/SvJae * C57BL/6 * FVB/NCrl | J:238768 | View | ||||
| prostate cancer |
Ptentm1Ppp/Pten+ Tg(Pbsn-TAg)15Tvd/0 |
involves: 129S1/Sv * C57BL/6 * DBA/2 | J:103408 | View | ||||
| prostate cancer |
Ptentm1Rdp/Ptentm1Rdp Terttm3Rdp/Terttm3Rdp Trp53tm1Brn/Trp53tm1Brn Tg(Pbsn-cre)4Prb/0 |
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2 | J:186105 | View | ||||
| prostate cancer |
Ptentm2.1Ppp/Pten+ Spry1tm1Jdli/Spry1tm1.1Jdli Spry2tm1Mrt/Spry2tm1.1Mrt Tg(Osr1-cre)4Mrt/0 |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N | J:192348 | View | ||||
| prostate cancer |
Ptentm2Mak/Ptentm2Mak Tg(KLK3-cre)13Saa/0 |
involves: 129P2/OlaHsd * C57BL/6 | J:214242 | View | ||||
| | prostate cancer |
Ctnnb1tm1Mmt/Ctnnb1+ Igs2tm1(CAG-Met)Zsu/Igs2+ Tg(Pbsn-cre)4Prb/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 * FVB/N | J:284956 | View | |||
| prostate cancer |
Ctnnb1tm1Mmt/Ctnnb1+ Tg(Pbsn-cre)4Prb/0 |
involves: 129X1/SvJ * C57BL/6 * DBA/2 | J:143034 | View | ||||
| prostate cancer |
Krastm1Bbd/Kras+ Tg(Pbsn-cre)4Prb/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 | J:143034 | View | ||||
| prostate cancer |
Krastm4Tyj/Kras+ Scribtm1.1Phum/Scribtm1.1Phum Tg(Pbsn-cre)20Fwan/0 |
involves: 129S4/SvJae * FVB/NCrl | J:178461 | View | ||||
| prostate cancer | Msmbtm1Xuan/Msmbtm1Xuan | either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * CD-1) | J:96884 | View | ||||
| prostate cancer | Nkx3-1tm1Hha/Nkx3-1+ | involves: 129S4/SvJae * C57BL/6 | J:63764 | View | ||||
| prostate cancer | Nkx3-1tm1Hha/Nkx3-1tm1Hha | involves: 129S4/SvJae * C57BL/6 | J:63764 | View | ||||
| prostate cancer | Nkx3-1tm1Mms/Nkx3-1+ | either: (involves: 129S1/Sv * 129S1/SvImJ) or (involves: 129S1/Sv * 129S1/SvImJ * C57BL/6J) | J:54465 | View | ||||
| prostate cancer | Nkx3-1tm1Mms/Nkx3-1tm1Mms | either: (involves: 129S1/Sv * 129S1/SvImJ) or (involves: 129S1/Sv * 129S1/SvImJ * C57BL/6J) | J:54465 | View | ||||
| prostate cancer |
Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0 |
involves: 129S6/SvEvTac * C57BL/6 * DBA/2 | J:204736 | View | ||||
| | prostate cancer |
Artm1(AR)Dmr/Y Tg(TRAMP)8247Ng/0 |
involves: 129S1/Sv * C57BL/6 | J:108849 | View | |||
| prostate cancer |
Artm2(AR)Dmr/Y Tg(TRAMP)8247Ng/0 |
involves: 129S1/Sv * C57BL/6 | J:108849 | View | ||||
| prostate cancer |
Artm3(AR)Dmr/Y Tg(TRAMP)8247Ng/0 |
involves: 129S1/Sv * C57BL/6 | J:108849 | View | ||||
| prostate cancer |
Brca2tm1Brn/Brca2tm1Brn Trp53tm1Brn/Trp53tm1Brn Tg(Pbsn-cre)4Prb/0 |
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 | J:161511 | View | ||||
| prostate cancer |
Cdkn2atm1Rdp/Cdkn2atm1Rdp Tg(tetO-BRAF*V600E)29Lc/0 Tg(Tyr-rtTA)37Lc/0 |
involves: 129/Sv * C57BL/6J * SJL | J:144358 | View | ||||
| Transgenes and Other Mutations | prostate adenocarcinoma | Tg(Pbsn-Tag)12T10Rjm/0 | involves: CD-1 | J:68483 | View | |||
| prostate cancer | Tg(ARR2/Pbsn-MYC)7Key/? | involves: FVB/N | J:85480 | View | ||||
| prostate cancer | Tg(C3-1-TAg)cJeg/0 | involves: FVB/N | J:52786 | View | ||||
| prostate cancer |
Tg(CAG-SAC/EGFP)35Rang/0 Tg(TRAMP)8247Ng/0 |
involves: C3H * C57BL/6 | J:125633 | View | ||||
| prostate cancer | Tg(Ggamma-T)15Cps/0 | involves: C57BL/6J * CBA/J | J:38778 | View | ||||
| prostate cancer | Tg(Ggamma-T)15Cps/Tg(Ggamma-T)15Cps | involves: C57BL/6J * CBA/J | J:38778 | View | ||||
| prostate cancer |
Tg(H-2K1-Lrp5/Fkbp1a,-luc*)#Dmps/0 Tg(Pbsn-Fgfr1/Fkbp1a)#aDmsp/0 |
involves: FVB/N | J:206727 | View | ||||
| prostate cancer | Tg(Msmb-TAg)183-2Xuan/0 | involves: C57BL/6 * CBA | J:80313 | View | ||||
| prostate cancer | Tg(Msmb-TAg)186-3Xuan/0 | involves: C57BL/6 * CBA | J:80313 | View | ||||
| prostate cancer | Tg(Pbsn-Ar*E231G)7353Ng/0 | involves: FVB/N | J:96117 | View | ||||
| prostate cancer | Tg(Pbsn-ERG*)1Vv/0 | involves: 129S1/SvImJ * C57BL/6J * CBA | J:222916 | View | ||||
| prostate cancer | Tg(Pbsn-Fgfr1/Fkbp1a)#aDmsp/0 | FVB-Tg(Pbsn-Fgfr1/Fkbp1a)#aDmsp | J:130340 | View | ||||
| prostate cancer |
Tg(Pbsn-IGF1*)5305Ng/0 Tg(TRAMP)8247Ng/0 |
involves: C57BL/6 * FVB/N | J:144539 | View | ||||
| prostate cancer | Tg(Pbsn-MYC)6Key/? | involves: FVB | J:85480 | View | ||||
| prostate cancer | Tg(Pbsn-MYC)#Tt/? | involves: C57BL/6J | J:205395 | View | ||||
| prostate cancer | Tg(Pbsn-Tag)12T7fRjm/0 | involves: CD-1 | J:48623 | View | ||||
| prostate cancer | Tg(Pbsn-TAg)15Tvd/0 | involves: C57BL/6 * DBA/2 | J:103408 | View | ||||
| prostate cancer | Tg(TRAMP)8247Ng/0 | involves: C57BL/6 | J:65303 | View | ||||
| Additional Complex Models | prostate adenocarcinoma |
Gt(ROSA)26Sortm1(CAG-AR)Zsu/Gt(ROSA)26Sor+ Tg(Osr1-cre)4Mrt/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N | J:234601 | View | |||
| prostate adenocarcinoma |
Gt(ROSA)26Sortm1(CAG-AR)Zsu/Gt(ROSA)26Sortm1(CAG-AR)Zsu Tg(Osr1-cre)4Mrt/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N | J:234601 | View | ||||
| prostate cancer |
Col1a1tm1(tetO-YAP1*)Fcam/Col1a1+ Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+ Tg(Pbsn-cre)4Prb/0 |
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * DBA/2 | J:222916 | View | ||||
| prostate neuroendocrine neoplasm |
Gt(ROSA)26Sortm1(CAG-MYCN,-luc)Jhsc/Gt(ROSA)26Sor+ Ptentm2.1Ppp/Ptentm2.1Ppp Rb1tm2Brn/Rb1+ Tg(Pbsn-cre)4Prb/0 |
involves: 129 * 129S1/Sv * 129S6/SvEvTac * C57BL/6 * DBA/2 | J:307910 | View | ||||
| prostate neuroendocrine neoplasm |
Gt(ROSA)26Sortm1(CAG-MYCN,-luc)Jhsc/Gt(ROSA)26Sor+ Ptentm2.1Ppp/Ptentm2.1Ppp Rb1tm2Brn/Rb1tm2Brn Tg(Pbsn-cre)4Prb/0 |
involves: 129 * 129S1/Sv * 129S6/SvEvTac * C57BL/6 * DBA/2 | J:307910 | View | ||||