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All mouse models of lymphoid leukemia with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
 | acute lymphoblastic leukemia |
Ezh2tm2Sho/Ezh2tm2.1Sho Tg(Mx1-cre)1Cgn/0 |
involves: 129S1/Sv * C57BL/6 * CBA | J:182211 | View | |||
| acute lymphoblastic leukemia |
Ezh2tm2Sho/Ezh2tm2Sho Tg(Mx1-cre)1Cgn/0 |
involves: 129S1/Sv * C57BL/6 * CBA | J:182211 | View | ||||
| acute lymphoblastic leukemia |
Kmt2atm1Saam/Kmt2a+ Tg(Mx1-cre)1Cgn/0 |
involves: 129S1/Sv * C57BL/6 * CBA | J:140628 | View | ||||
| acute lymphoblastic leukemia |
Ptentm1Hwu/Ptentm1Hwu Tg(Mx1-cre)1Cgn/0 |
involves: 129S4/SvJae * C57BL/6 * CBA | J:169097 | View | ||||
| acute lymphoblastic leukemia | Tg(CD2-Lmo2)#Thr/0 | involves: C57BL/6 * CBA | J:102058 | View | ||||
| acute lymphoblastic leukemia | Tg(Lck-Notch3)#Issc/0 | involves: C57BL/6 * DBA/2 | J:63300 | View | ||||
| lymphoid leukemia | Tg(Lck-Tal1)4709Led/0 | FVB/N-Tg(Lck-Tal1)4709Led | J:36076 | View | ||||
| T-cell acute lymphoblastic leukemia |
Nbnem7Jpt/Nbntm2Zqw Tg(VAV1-cre)1Graf/0 |
involves: 129P2/OlaHsd | J:277750 | View | ||||
| T-cell acute lymphoblastic leukemia | Tg(H2-K-Hmga1)#Lmsr/0 | involves: C57BL/6 * SJL | J:90252 | View | ||||
| T-cell adult acute lymphocytic leukemia |
Gt(ROSA)26Sortm18(Zeb2)Jhai/Gt(ROSA)26Sortm18(Zeb2)Jhai Tg(Cd4-cre)1Cwi/0 |
involves: C57BL/6 * CD-1 * DBA/2 | J:263520 | View | ||||
| T-cell adult acute lymphocytic leukemia |
Gt(ROSA)26Sortm18(Zeb2)Jhai/Gt(ROSA)26Sortm18(Zeb2)Jhai Tg(Tek-cre)1Ywa/0 |
involves: C57BL/6 * CD-1 * SJL | J:263520 | View | ||||
| T-cell adult acute lymphocytic leukemia | Tg(Lck-Tax)53Hall/0 | involves: C57BL/6 | J:129531, J:214623 | View | ||||
 | acute lymphoblastic leukemia |
Ikzf1tm1Kast/Ikzf1+ Tg(BCR/ABL)623Hkp/0 |
involves: 129S2/SvPas * C57BL/6 * CBA | J:160846 | View | |||
| Transgenes and Other Mutations | acute leukemia | Tg(Ly6a-SET/NUP214)2969Gcg/0 | involves: FVB/NJ | J:142938 | View | |||
| acute lymphoblastic leukemia | Tg(Igh-HMGA2)#Cro/0 | FVB/N-Tg(Igh-HMGA2)#Cro | J:233225 | View | ||||
| chronic lymphocytic leukemia | Del(14Trim13-Dleu2)4Rdf/Del(14Trim13-Dleu2)4Rdf | involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:156946 | View | ||||
| chronic lymphocytic leukemia |
Del(14Trim13-Rnaseh2b)6Rdf/+ Cd19tm1(cre)Cgn/Cd19+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:179879 | View | ||||
| chronic lymphocytic leukemia |
Is(14)1Rdf Is(14)2Rdf/Del(14Trim13-Dleu2)4Rdf Cd19tm1(cre)Cgn/Cd19+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:156946 | View | ||||
| chronic lymphocytic leukemia |
Is(14)1Rdf Is(14)5Rdf/Del(14Trim13-Rnaseh2b)6Rdf Cd19tm1(cre)Cgn/Cd19+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:179879 | View | ||||
| chronic lymphocytic leukemia |
Mirc30em1Hhzg/Mirc30em1Hhzg Tg(Vav1-cre)#Cgp/0 |
involves: 129S4/SvJae * C57BL/6 * C57BL/6NRj | J:320883 | View | ||||
| chronic lymphocytic leukemia | Mirc30tm1.2Rdf/Mirc30tm1.2Rdf | involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:156946 | View | ||||
| chronic lymphocytic leukemia | Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0 | FVB/N-Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro | J:162077 | View | ||||
| chronic lymphocytic leukemia |
Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0 Tg(Igh-V186.2-TCL1A)3Cro/0 |
involves: C3H * C57BL/6 * FVB/N | J:162077 | View | ||||
| chronic lymphocytic leukemia | Tg(Igh-ROR1)1Kip/0 | C57BL/6-Tg(Igh-ROR1)1Kip | J:206368 | View | ||||
| chronic lymphocytic leukemia |
Tg(Igh-ROR1)1Kip/0 Tg(Igh-V186.2-TCL1A)3Cro/0 |
B6.Cg-Tg(Igh-ROR1)1Kip Tg(Igh-V186.2-TCL1A)3Cro | J:206368 | View | ||||
| chronic lymphocytic leukemia | Tg(Igh-TCL1A)1Ypek/0 | FVB/N-Tg(Igh-TCL1A)1Ypek | J:160184 | View | ||||
| chronic lymphocytic leukemia | Tg(Igh-V186.2-TCL1A)3Cro/0 | B6.Cg-Tg(Igh-V186.2-TCL1A)3Cro | J:206368 | View | ||||
| chronic lymphocytic leukemia | Tg(Igh-V186.2-TCL1A)3Cro/0 | involves: C3H * C57BL/6 | J:76574 | View | ||||
| chronic lymphocytic leukemia | Tg(Lck-TNFSF13)3919Mhah/0 | B6.Cg-Tg(Lck-TNFSF13)3919Mhah | J:94628 | View | ||||
| Additional Complex Models | acute leukemia |
Cd3etm1Mal/Cd3etm1Mal Tg(Tcrb-TCF3/PBX1)23Gusa/0 |
involves: C3H * C57BL/6 * C57BL/6J | J:95693 | View | |||
| acute lymphoblastic leukemia |
Etv6tm1.1(RUNX1,hsb5)Lvdw/Etv6+ TgTn(sb-T2/Onc)76Dla/0 |
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * FVB/N | J:174866 | View | ||||
| acute lymphoblastic leukemia |
Tcf3tm1(PBX1)Mlc/Tcf3+ Cd19tm1(cre)Cgn/Cd19+ |
involves: 129P2/OlaHsd * C57BL/6 | J:226241 | View | ||||
| acute lymphoblastic leukemia |
Tcf3tm1(PBX1)Mlc/Tcf3+ Cd79atm1(cre)Reth/Cd79a+ |
involves: BALB/c * C57BL/6 | J:226241 | View | ||||
| acute lymphoblastic leukemia |
Tcf3tm1(PBX1)Mlc/Tcf3+ Tg(Mx1-cre)1Cgn/0 |
involves: C57BL/6 * C57BL/6J * CBA/J | J:226241 | View | ||||
| acute lymphoblastic leukemia |
Tg(Lck-LMO1)11Sjk/0 Tg(STIL-TAL1)A5(3)Alpa/0 |
involves: C3H * C3H/HeRos * C57BL/6 * C57BL/10Ros | J:40868 | View | ||||
| acute lymphoblastic leukemia |
Zfp36l1tm1.1Tnr/Zfp36l1tm1.1Tnr Zfp36l2tm1.1Tnr/Zfp36l2tm1.1Tnr Tg(CD2-icre)4Kio/0 |
involves: C57BL/6 * C57BL/10 * CBA/Ca * SJL | J:162388 | View | ||||
| chronic lymphocytic leukemia | Ightm1.1(Tag)Rwhe/Igh+ | involves: 129P2/OlaHsd * C57BL/6 | J:150315 | View | ||||
| chronic lymphocytic leukemia | Ightm2.1(Tag)Rwhe/Igh+ | involves: 129P2/OlaHsd * C57BL/6 | J:150315 | View | ||||
| chronic lymphocytic leukemia |
Ighatm1(Myc)Janz/Igha+ Tg(Tnfsf13b)1Fma/0 |
involves: 129S1/Sv * C57BL/6 * DBA/2J | J:166158 | View | ||||
| chronic lymphocytic leukemia |
Is(14)1Rdf/Is(14)1Rdf Is(14)5Rdf/Is(14)5Rdf Cd19tm1(cre)Cgn/Cd19+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:179879 | View | ||||
| chronic lymphocytic leukemia |
Tg(BCL2/IGH)#Jcre/0 Tg(H2-K/Igh-Traf2*)#Ywc/0 |
involves: BALB/c * C57BL/6 * CBA/J * FVB/N * SJL/J * SWR/J | J:94116 | View | ||||
| lymphoid leukemia |
Col1a1tm4(tetO-GFP/RNAi:Apc)Slowe/Col1a1+ Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+ |
involves: 129S4/SvJae * C57BL/6 | J:171191 | View | ||||