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All mouse models of Alzheimer's disease with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | Alzheimer's disease | Apptm1.1Cep/App+ | involves: 129S1/Sv * 129X1/SvJ | J:35500 | View | |||
| Alzheimer's disease | Apptm1.1Cep/Apptm1.1Cep | involves: 129S1/Sv * 129X1/SvJ | J:35500 | View | ||||
| Alzheimer's disease |
Apptm1.1Cep/Apptm1.1Cep Psen1tm1Dgf/Psen1tm1Dgf |
involves: 129S1/Sv * 129X1/SvJ * CD-1 | J:102425 | View | ||||
| Alzheimer's disease | Apptm1Cep/App+ | involves: 129S1/Sv * 129X1/SvJ | J:35500 | View | ||||
| Alzheimer's disease | Apptm1Cep/Apptm1Cep | involves: 129S1/Sv * 129X1/SvJ | J:35500 | View | ||||
| Alzheimer's disease |
Apptm1Ck/Apptm1Ck Psen1tm1Mpm/Psen1tm1Mpm |
involves: 129 * 129S1/Sv * 129X1/SvJ | J:191170 | View | ||||
| Alzheimer's disease |
Apptm1Ck/Apptm1Ck Psen1tm1Mpm/Psen1tm1Mpm Tg(MAPT)8cPdav/0 |
B6.Cg-Tg(MAPT)8cPdav Psen1tm1Mpm Apptm1Ck | J:209782 | View | ||||
| Alzheimer's disease | Apptm1Dbo/Apptm1Dbo | involves: 129S7/SvEvBrd * C57BL/6J | J:53824 | View | ||||
| Alzheimer's disease |
Apptm1Dbo/Apptm1Dbo Npc1m1N/Npc1m1N |
C.Cg-Apptm1Dbo Npc1m1N | J:172769 | View | ||||
| Alzheimer's disease | Apptm1Ini/App+ | involves: C57BL/6 * CBA * CD-1 | J:90296 | View | ||||
| Alzheimer's disease | Apptm2.1Tcs/Apptm2.1Tcs | involves: C57BL/6 | J:212758 | View | ||||
| Alzheimer's disease | Apptm3.1Tcs/Apptm3.1Tcs | involves: C57BL/6 | J:212758 | View | ||||
| Alzheimer's disease |
Leprdb/Lepr+ Tg(APPswe,PSEN1dE9)85Dbo/0 |
involves: C3H * C57BL/6 * C57BLKS/J | J:186924 | View | ||||
| Alzheimer's disease |
Lrp1tm2Her/Lrp1tm2Her Tg(APP695)3Dbo/0 Tg(PSEN1)5Dbo/0 Tg(Tagln-cre)1Her/0 |
involves: 129S7/SvEvBrd * C3H/HeJ * C57BL/6 * C57BL/6J * SJL | J:192453 | View | ||||
| Alzheimer's disease |
Lrp1tm2Her/Lrp1tm2Her Tg(Camk2a-cre)T29-1Stl/0 |
involves: 129S7/SvEvBrd * BALB/c * C57BL | J:167724 | View | ||||
| Alzheimer's disease | Mmetm1Cge/Mmetm1Cge | involves: 129S4/SvJae * C57BL/6 | J:69830 | View | ||||
| Alzheimer's disease |
Omptm1(tTA)Gogo/Omp+ Tg(tetO-APPSwInd)Dbo/0 |
involves: 129 * C3H/HeJ * C57BL/6J | J:199798 | View | ||||
| Alzheimer's disease | Plautm1Mlg/Plautm1Mlg | involves: 129S2/SvPas * C57BL/6 | J:104962 | View | ||||
| Alzheimer's disease | Psen1tm1Bdes/Psen1tm1Bdes | involves: 129P2/OlaHsd | J:71037 | View | ||||
| Alzheimer's disease |
Psen1tm1Dgf/Psen1tm1Dgf Tg(APPSWE)2576Kha/? |
involves: 129 * C57BL/6 * CD-1 * SJL | J:102425 | View | ||||
| Alzheimer's disease |
Psen1tm1Jzt/Psen1tm1Jzt Psen2tm1Ber/Psen2tm1Ber Tg(Camk2a-cre)T29-1Stl/0 |
involves: C57BL/6 * CBA | J:90685 | View | ||||
| Alzheimer's disease |
Psen1tm1Jzt/Psen1tm1Jzt Tg(Camk2a-cre)T29-1Stl/0 |
involves: C57BL/6 * CBA | J:73252 | View | ||||
| Alzheimer's disease |
Psen1tm1Lpr/Psen1tm1Lpr Tg(Thy1-APPSL)28Lpr/0 |
either: 129/Sv or (involves: 129/Sv * C57BL/6) | J:93770 | View | ||||
| Alzheimer's disease |
Psen1tm1Lpr/Psen1tm1Lpr Tg(Thy1-APPSL)28Lpr/0 |
involves: 129 * C57BL/6 * CBA | J:128106 | View | ||||
| Alzheimer's disease | Psen1tm1Mpm/Psen1tm1Mpm | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:51950 | View | ||||
| Alzheimer's disease |
Psen1tm1Mpm/Psen1tm1Mpm Tg(APPSwe,tauP301L)1Lfa/? |
B6.Cg-Psen1tm1Mpm Tg(APPSwe,tauP301L)1Lfa | J:170670 | View | ||||
| Alzheimer's disease |
Psen1tm1Mpm/Psen1tm1Mpm Tg(APPSwe,tauP301L)1Lfa/Tg(APPSwe,tauP301L)1Lfa |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:99604 | View | ||||
| Alzheimer's disease | Psen1tm1Mpm/Psen1tm1Pcw | involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 | J:91277 | View | ||||
| Alzheimer's disease | Psen1tm1Shn/Psen1tm1Shn | involves: 129S7/SvEvBrd * C57BL/6 | J:40365 | View | ||||
| Alzheimer's disease | Psen1tm1Tak/Psen1tm1Tak | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:99353 | View | ||||
| Alzheimer's disease |
Psen1tm1Vln/Psen1tm1Vln Tg(Thy1-cre)1Vln/0 |
involves: FVB/N | J:87229 | View | ||||
| Alzheimer's disease |
Psen1tm1Zhe/Psen1tm1Zhe Tg(APPSWE)2576Kha/? |
involves: 129S7/SvEvBrd * C57BL/6 * SJL | J:107251 | View | ||||
| Alzheimer's disease |
Psen1tm2Shn/Psen1tm4.1Shn Psen2tm1Haa/Psen2tm1Haa Tg(Camk2a-cre)1Shn/0 |
involves: 129 * 129S4/SvJae * C57BL/6 * C57BL/6J * CBA | J:219929 | View | ||||
| Alzheimer's disease |
Psen1tm4.1Shn/Psen1+ Psen2tm1Haa/Psen2tm1Haa |
involves: 129 * C57BL/6 * C57BL/6J | J:219929 | View | ||||
| Alzheimer's disease | Tg(APPswe,PSEN1dE9)85Dbo/0 | B6.Cg-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax | J:160557, J:172426, J:234430 | View | ||||
| Alzheimer's disease | Tg(APPswe,PSEN1dE9)85Dbo/0 | B6;C3-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax | J:113199 | View | ||||
| Alzheimer's disease | Tg(APPswe,PSEN1dE9)85Dbo/0 | D2.Cg-Tg(APPswe,PSEN1dE9)85Dbo | J:227541 | View | ||||
| Alzheimer's disease | Tg(APPswe,PSEN1dE9)85Dbo/0 | involves: C3H/HeH * C57BL/6JNju | J:275175 | View | ||||
| Alzheimer's disease | Tg(APPswe,PSEN1dE9)85Dbo/0 | involves: C3H/HeJ * C57BL/6J | J:87691, J:113200 | View | ||||
| Alzheimer's disease | Tg(Camk2a-App*,-Apbb1)25Spim/0 | C57BL/6-Tg(Camk2a-App*,-Apbb1)25Spim | J:153738 | View | ||||
| Alzheimer's disease |
Tg(Camk2a-tTA)1Mmay/0 Tg(tetO-APPSwInd)18Dbo/0 |
involves: C3H/HeJ * C57BL/6 * CBA | J:109829 | View | ||||
| Alzheimer's disease |
Tg(Camk2a-tTA)1Mmay/0 Tg(tetO-APPSwInd)102Dbo/0 |
involves: C3H/HeJ * C57BL/6 * CBA | J:109829 | View | ||||
| Alzheimer's disease |
Tg(Camk2a-tTA)1Mmay/0 Tg(tetO-APPSwInd)107Dbo/0 |
involves: C3H/HeJ * C57BL/6 * CBA | J:109829 | View | ||||
| Alzheimer's disease |
Tg(Camk2a-tTA)1Mmay/0 Tg(tetO-APPSwInd)Dbo/0 |
involves: C3H/HeJ * C57BL/6J | J:236737 | View | ||||
| Alzheimer's disease 3 |
Psen1tm1Lpr/Psen1tm1Lpr Tg(Thy1-APPSL)28Lpr/0 |
either: 129/Sv or (involves: 129/Sv * C57BL/6) | J:93770 | View | ||||
| Alzheimer's disease 3 | Psen1tm1Mpm/Psen1tm1Mpm | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:51950 | View | ||||
| Alzheimer's disease 3 | Psen1tm1Mpm/Psen1tm1Pcw | involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 | J:91277 | View | ||||
| Alzheimer's disease 3 | Psen1tm1Shn/Psen1tm1Shn | involves: 129S7/SvEvBrd * C57BL/6 | J:40365 | View | ||||
| Alzheimer's disease 3 | Psen1tm1Tak/Psen1+ | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:108326 | View | ||||
| Alzheimer's disease 3 |
Psen1tm1Vln/Psen1tm1Vln Tg(Thy1-cre)1Vln/0 |
involves: FVB/N | J:87229 | View | ||||
| | Alzheimer's disease | Cav1tm1Mls/Cav1tm1Mls | Not Specified | J:168335 | View | |||
| Alzheimer's disease | Il33tm1(KOMP)Vlcg/Il33tm1(KOMP)Vlcg | C57BL/6-Il33tm1(KOMP)Vlcg | J:251814 | View | ||||
| Alzheimer's disease | Pin1tm1Tuc/Pin1tm1Tuc | involves: 129 * 129P2/OlaHsd * C57BL/6 | J:107132 | View | ||||
| Alzheimer's disease |
Pin1tm1Tuc/Pin1tm1Tuc Tg(APPSWE)2576Kha/0 |
involves: 129 * 129P2/OlaHsd * C57BL/6 * SJL | J:107132 | View | ||||
| Alzheimer's disease | Plcb1tm1Hssh/Plcb1tm1Hssh | Not Specified | J:43077 | View | ||||
| | Alzheimer's disease |
Apoa4tm1Bres/Apoa4tm1Bres Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/? |
involves: 129S4/SvJae * C57BL/6 * SJL | J:169682 | View | |||
| Alzheimer's disease |
Apoetm1Unc/Apoetm1Unc Clutm1Jakh/Clutm1Jakh Tg(APPV717F)109Ili/Tg(APPV717F)109Ili |
involves: 129P2/OlaHsd * 129S2/SvPas | J:107702 | View | ||||
| Alzheimer's disease |
Apoetm1Unc/Apoetm1Unc Tg(APPV717F)109Ili/Tg(APPV717F)109Ili |
involves: 129P2/OlaHsd | J:107702 | View | ||||
| Alzheimer's disease |
Apoetm3(APOE*4)Mae/Apoetm3(APOE*4)Mae Tg(APPSWE)2576Kha/? |
involves: 129P2/OlaHsd * C57BL/6 * SJL | J:98636 | View | ||||
| Alzheimer's disease |
Apoetm3(APOE*4)Mae/Apoetm3(APOE*4)Mae Tg(Thy1-APPSwDutIowa)BWevn/? |
involves: 129P2/OlaHsd * C57BL/6 | J:136318 | View | ||||
| Alzheimer's disease |
Klc1tm1Gsn/Klc1+ Tg(APP695)3Dbo/? |
involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ * C57BL/6 | J:96346 | View | ||||
| Alzheimer's disease |
Ldlrtm1Her/Ldlrtm1Her Tg(APPSWE)2576Kha/0 |
involves: 129S7/SvEvBrd * C57BL/6 * SJL | J:114480 | View | ||||
| Alzheimer's disease |
Mapttm1(EGFP)Klt/Mapttm1(EGFP)Klt Tg(MAPT)8cPdav/0 |
B6.Cg-Tg(MAPT)8cPdav Mapttm1(EGFP)Klt/J | J:172426 | View | ||||
| Alzheimer's disease |
Mapttm1(EGFP)Klt/Mapttm1(EGFP)Klt Tg(MAPT)8cPdav/? |
involves: 129S4/SvJae * C57BL/6 * Swiss Webster | J:84638, J:174270 | View | ||||
| Alzheimer's disease |
Sorl1tm1Tew/Sorl1tm1Tew Tg(APP695)3Dbo/0 Tg(PSEN1dE9)S9Dbo/0 |
involves: 129 * C3H/HeJ * C57BL/6 | J:142501 | View | ||||
| Alzheimer's disease |
Tg(APPSWE)2576Kha/? Tg(EIF1AX-Aldh2*E487K)101Oht/? |
involves: C57BL/6 * SJL | J:219346 | View | ||||
| Alzheimer's disease 4 |
Psen1tm1Jzt/Psen1tm1Jzt Psen2tm1Ber/Psen2tm1Ber Tg(Camk2a-cre)T29-1Stl/0 |
involves: C57BL/6 * CBA | J:90685 | View | ||||
| Transgenes and Other Mutations | Alzheimer's disease |
Abcc1tm1Bor/Abcc1tm1Bor Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr/0 |
FVB.Cg-Abcc1tm1Bor Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr | J:178230 | View | |||
| Alzheimer's disease |
Clutm1Jakh/Clutm1Jakh Tg(APPV717F)109Ili/Tg(APPV717F)109Ili |
involves: 129S2/SvPas | J:78357 | View | ||||
| Alzheimer's disease |
Msr1tm1Csk/Msr1tm1Csk Tg(APPV717F)109Ili/? |
involves: 129X1/SvJ * C57BL/6 * DBA/2 * ICR | J:58338 | View | ||||
| Alzheimer's disease |
Nos2tm1Lau/Nos2tm1Lau Tg(APPSWE)2576Kha/0 |
involves: 129P2/OlaHsd * C57BL/6 * SJL | J:112919 | View | ||||
| Alzheimer's disease |
Nos2tm1Lau/Nos2tm1Lau Tg(Thy1-APPSwDutIowa)BWevn/? |
involves: C57BL/6 | J:132221 | View | ||||
| Alzheimer's disease |
Npc1m1N/Npc1m1N Tg(PRNP-APPSweInd)8Dwst/0 |
involves: BALB/c * C3H/HeJ * C57BL/6J | J:188345 | View | ||||
| Alzheimer's disease | Tg(ACTB-APP*V717F)1Colm/0 | involves: C57BL/6 * DBA | J:157859 | View | ||||
| Alzheimer's disease | Tg(APP695)3Dbo/0 | B6.C3-Tg(APP695)3Dbo | J:109847 | View | ||||
| Alzheimer's disease | Tg(APP695)3Dbo/0 | involves: C3H/HeJ * C57BL/6J | J:87691 | View | ||||
| Alzheimer's disease |
Tg(APP695)3Dbo/0 Tg(PSEN1)5Dbo/0 |
involves: C3H/HeJ * C57BL/6J | J:43788 | View | ||||
| Alzheimer's disease |
Tg(APP695)3Dbo/0 Tg(PSEN1dE9)S9Dbo/0 |
involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ * C57BL/6J | J:123534 | View | ||||
| Alzheimer's disease |
Tg(APP695)3Dbo/0 Tg(PSEN1dE9)S9Dbo/0 |
involves: C3H/HeJ * C57BL/6J | J:123534 | View | ||||
| Alzheimer's disease | Tg(APP)8.9Btla/Tg(APP)8.9Btla | involves: 129S2/SvPas | J:96742 | View | ||||
| Alzheimer's disease | Tg(APPSw)40Btla/0 | involves: 129S1/Sv * 129X1/SvJ | J:42613 | View | ||||
| Alzheimer's disease | Tg(APPSw)40Btla/Tg(APPSw)40Btla | B6.129-Tg(APPSw)40Btla | J:86629 | View | ||||
| Alzheimer's disease | Tg(APPSWE)2576Kha/0 | involves: 129S7/SvEvBrd * C57BL/6 * SJL | J:114480, J:180385 | View | ||||
| Alzheimer's disease | Tg(APPSWE)2576Kha/0 | involves: C57BL/6 * DBA/2 * SJL * SW | J:174270 | View | ||||
| Alzheimer's disease | Tg(APPSWE)2576Kha/0 | involves: C57BL/6 * SJL | J:119251 | View | ||||
| Alzheimer's disease |
Tg(APPSWE)2576Kha/0 Tg(PDGFB-PSEN1M146L)2Jhd/0 |
involves: C57BL/6 * DBA/2 * SJL * SW | J:174270 | View | ||||
| Alzheimer's disease |
Tg(APPSWE)2576Kha/0 Tg(Prnp-MAPT*P301L)JNPL3Hlmc/0 |
involves: C57BL/6 * DBA/2 * SJL * SW | J:100965 | View | ||||
| Alzheimer's disease |
Tg(APPSWE)2576Kha/0 Tg(PSEN1)5Dbo/0 |
involves: C57BL/6 * SJL | J:191088 | View | ||||
| Alzheimer's disease | Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0 | B6SJL-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax | J:214858 | View | ||||
| Alzheimer's disease | Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0 | involves: C57BL/6 * C57BL/6J * SJL | J:244104 | View | ||||
| Alzheimer's disease | Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0 | involves: C57BL/6 * SJL | J:112949 | View | ||||
| Alzheimer's disease |
Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0 Tg(Prnp-MAPT*P301S)PS19Vle/0 |
B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas Tg(Prnp-MAPT*P301S)PS19Vle | J:211723 | View | ||||
| Alzheimer's disease |
Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0 Tg(Thy1-MAPT*)30Schd/0 |
involves: C57BL/6 * C57BL/6J * CBA * SJL | J:201809 | View | ||||
| Alzheimer's disease | Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/? | involves: 129S4/SvJae * C57BL/6 * SJL | J:169682 | View | ||||
| Alzheimer's disease | Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas | B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax | J:229382 | View | ||||
| Alzheimer's disease | Tg(APPSwLon)96Btla/0 | involves: 129S4/SvJae | J:42613 | View | ||||
| Alzheimer's disease | Tg(APPV717F)109Ili/0 | B6.Cg-Tg(APPV717F)109Ili | J:244104 | View | ||||
| Alzheimer's disease | Tg(APPV717F)109Ili/0 | involves: BALB/c * C57BL * C57BL/6NTac | J:184975 | View | ||||
| Alzheimer's disease | Tg(APPV717F)109Ili/0 | Not Specified | J:23080 | View | ||||
| Alzheimer's disease |
Tg(APPV717F)109Ili/0 Tg(Prnp-MAPT*P301S)PS19Vle/0 |
involves: C3H * C57BL/6 | J:165441 | View | ||||
| Alzheimer's disease | Tg(APPV717F)109Ili/Tg(APPV717F)109Ili | Not Specified | J:78357 | View | ||||
| Alzheimer's disease |
Tg(Camk2a-tTA)1Mmay/0 Tg(tetO-CDK5R1/GFP)337Lht/0 |
involves: C57BL/6J | J:177847 | View | ||||
| Alzheimer's disease |
Tg(Camk2a-tTA)1Mmay/0 Tg(tetO-MAPT*K280,-luc)#Eman/0 |
involves: C57BL/6 | J:131379, J:169532 | View | ||||
| Alzheimer's disease |
Tg(Camk2a-tTA)1Mmay/0 Tg(tetO/Prnp-APP*Swe*Lon)9191Krz/0 |
involves: 129S6/SvEvTac * FVB/N | J:235351 | View | ||||
| Alzheimer's disease | Tg(CMV-IgkvaD11)BCat/Tg(CMV-IgkvaD11)BCat | involves: 129 * C57BL/6 * SJL | J:210074 | View | ||||
| Alzheimer's disease | Tg(CMV-IgkvaD11)BCat/Tg(CMV-IgkvaD11)BCat | involves: C57BL/6 * SJL | J:212312 | View | ||||
| Alzheimer's disease | Tg(DMD-APP*)7Neve/0 | involves: C57BL/6 * SJL | J:105050, J:100978 | View | ||||
| Alzheimer's disease | Tg(DMD-APP*)18Neve/0 | involves: C57BL/6 * SJL | J:100978 | View | ||||
| Alzheimer's disease | Tg(Eno2-APP*Ind)#Kakiz/Tg(Eno2-APP*Ind)#Kakiz | involves: C57BL/6 | J:212692 | View | ||||
| Alzheimer's disease | Tg(Eno2-PSEN2)2348Ykk/0 | involves: C57BL/6 * DBA/2 | J:76934 | View | ||||
| Alzheimer's disease | Tg(Eno2-PSEN2*)1480Ykk/0 | involves: C57BL/6 * DBA/2 | J:76934 | View | ||||
| Alzheimer's disease |
Tg(GFAP-tTA)6Hyms/0 Tg(tetO-HMOX1)6Hyms/0 |
involves: FVB/N | J:190573 | View | ||||
| Alzheimer's disease |
Tg(GSK3B*S9A)1Vln/0 Tg(Thy1-MAPT)1Vln/Tg(Thy1-MAPT)1Vln |
involves: FVB | J:100971 | View | ||||
| Alzheimer's disease |
Tg(GSK3B*S9A)1Vln/0 Tg(Thy1-MAPT)2Vln/Tg(Thy1-MAPT)2Vln |
involves: FVB | J:100971 | View | ||||
| Alzheimer's disease |
Tg(Hmgcr-PSEN1*M146L)#Lpr/0 Tg(PDGFB-APPSwDutLon)46Lpr/0 |
involves: C57BL/6 * CBA | J:86694 | View | ||||
| Alzheimer's disease |
Tg(Hmgcr-PSEN1*M146L)#Lpr/0 Tg(Thy1-APPSL)28Lpr/0 |
involves: C57BL/6 * CBA | J:86694, J:99507 | View | ||||
| Alzheimer's disease |
Tg(Hmgcr-PSEN1*M146L)#Lpr/0 Tg(Thy1-APPLon)2Vln/0 |
involves: C57BL/6 * CBA * FVB/N | J:86694 | View | ||||
| Alzheimer's disease | Tg(Mapt-MAPT*)#Hanr/0 | involves: BALB/c * C57BL/6 | J:137947 | View | ||||
| Alzheimer's disease | Tg(NEFL-APP)#Nalb/0 | involves: C57BL/6 * C3H | J:202532 | View | ||||
| Alzheimer's disease | Tg(PDGFB-APPInd)F17Plhn/0 | C57BL/6-Tg(PDGFB-APPInd)F17Plhn | J:107982 | View | ||||
| Alzheimer's disease | Tg(PDGFB-APPSwDutLon)46Lpr/0 | involves: C57BL/6 * CBA | J:86694 | View | ||||
| Alzheimer's disease | Tg(PDGFB-APPSwInd)J9Lms/0 | involves: C57BL/6 * DBA/2 | J:62290 | View | ||||
| Alzheimer's disease | Tg(PDGFB-MAPT*V337M)1Atak/0 | involves: C57BL/6 * SJL | J:100964 | View | ||||
| Alzheimer's disease | Tg(Prnp-APP*)1Hmor/0 | B6.Cg-Tg(Prnp-APP*)1Hmor | J:159623 | View | ||||
| Alzheimer's disease | Tg(Prnp-App/APPswe)E1-2Dbo/0 | B6.C3-Tg(Prnp-App/APPswe)E1-2Dbo | J:109847 | View | ||||
| Alzheimer's disease | Tg(Prnp-APPSweArc)#Rmni/0 | involves: C57BL/6 * DBA/2 | J:239408 | View | ||||
| Alzheimer's disease | Tg(PRNP-APPSweInd)8Dwst/0 | involves: C3H/HeJ * C57BL/6J | J:166801 | View | ||||
| Alzheimer's disease | Tg(PRNP-APPSweInd)8Dwst/? | involves: 129S6/SvEvTac | J:113199 | View | ||||
| Alzheimer's disease | Tg(PRNP-APPSweInd)19959Dwst/0 | involves: 129S6/SvEvTac * FVB/N | J:177369 | View | ||||
| Alzheimer's disease | Tg(Prnp-ITM2B/APP695*40)1Emcg/0 | involves: C3H * C57BL/6 | J:101023 | View | ||||
| Alzheimer's disease | Tg(Prnp-ITM2B/APP695*42)A12Emcg/0 | involves: C3H * C57BL/6 | J:101023 | View | ||||
| Alzheimer's disease | Tg(Prnp-MAPT)7Vle/0 | involves: C57BL/6 * SJL | J:61052 | View | ||||
| Alzheimer's disease | Tg(Prnp-MAPT)43Vle/0 | involves: C57BL/6 * DBA/2 | J:61052 | View | ||||
| Alzheimer's disease | Tg(Prnp-MAPT*K274Q*K281Q)286Lgn/0 | involves: C57BL/6 * FVB/N | J:230252 | View | ||||
| Alzheimer's disease | Tg(Prnp-MAPT*P301L)JNPL3Hlmc/0 | involves: C57BL/6 * DBA/2 * SJL * SW | J:100965 | View | ||||
| Alzheimer's disease | Tg(Prnp-MAPT*P301S)PS19Vle/0 | B6.Cg-Tg(Prnp-MAPT*P301S)PS19Vle | J:174441 | View | ||||
| Alzheimer's disease | Tg(PSEN1dE9)S9Dbo/0 | involves: C3H/HeJ * C57BL/6J | J:104147 | View | ||||
| Alzheimer's disease | Tg(PSEN1H163R)G9Btla/0 | involves: 129S4/SvJae | J:58050 | View | ||||
| Alzheimer's disease | Tg(Thy1-APP)3Somm/0 | B6.Cg-Tg(Thy1-APP)3Somm | J:80449 | View | ||||
| Alzheimer's disease | Tg(Thy1-APP)3Somm/0 | involves: C57BL/6 * C57BL/6J * DBA/2 | J:345459 | View | ||||
| Alzheimer's disease | Tg(Thy1-APP)3Somm/0 | involves: C57BL/6J * DBA/2 | J:44603 | View | ||||
| Alzheimer's disease | Tg(Thy1-APP*)2Tbay/0 | C57BL/6J-Tg(Thy1-APP*)2Tbay | J:275188 | View | ||||
| Alzheimer's disease | Tg(Thy1-APP*Swe*Ind)fAccu/0 | involves: C3H * C57BL/6 | J:251735 | View | ||||
| Alzheimer's disease | Tg(Thy1-APPSL)28Lpr/0 | involves: C57BL/6 * CBA | J:86694, J:99507 | View | ||||
| Alzheimer's disease | Tg(Thy1-APPArc)M8Cagr/0 | involves: C57BL/6 * CBA | J:168288 | View | ||||
| Alzheimer's disease | Tg(Thy1-APPArc)M8Cagr/Tg(Thy1-APPArc)M8Cagr | involves: C57BL/6 * CBA | J:188191 | View | ||||
| Alzheimer's disease | Tg(Thy1-APPLon)2Vln/0 | involves: C57BL/6 * CBA * FVB/N | J:86694 | View | ||||
| Alzheimer's disease | Tg(Thy1-APPLon)2Vln/0 | involves: FVB/N | J:93635 | View | ||||
| Alzheimer's disease |
Tg(Thy1-APPLon)2Vln/0 Tg(Thy1-BACE1)16Vln/0 |
involves: C57BL/6 * DBA * FVB/N | J:93635 | View | ||||
| Alzheimer's disease | Tg(Thy1-APPSw)10Jiri/0 | involves: C3H * C57BL/6 | J:128647 | View | ||||
| Alzheimer's disease |
Tg(Thy1-APPSw)10Jiri/0 Tg(Thy1-PSEN1*M146V)#Jiri/0 |
B6.Cg-Tg(Thy1-APPSw)10Jiri Tg(Thy1-PSEN1*M146V)#Jiri | J:156577 | View | ||||
| Alzheimer's disease |
Tg(Thy1-APPSw)10Jiri/0 Tg(Thy1-PSEN1*M146V)#Jiri/0 |
involves: C3H * C57BL/6 | J:222897 | View | ||||
| Alzheimer's disease | Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr/0 | C57BL/6-Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr | J:180835 | View | ||||
| Alzheimer's disease | Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr/? | involves: C57BL/6 | J:234763 | View | ||||
| Alzheimer's disease | Tg(Thy1-APPSwDutIowa)BWevn/0 | involves: C57BL/6 | J:89848 | View | ||||
| Alzheimer's disease | Tg(Thy1-APPSweArc)BLngn/0 | B6J.Cg-Tg(Thy1-APPSweArc)BLngn | J:162999 | View | ||||
| Alzheimer's disease | Tg(Thy1-APPSweAut)A7Tiwa/0 | Not Specified | J:204270 | View | ||||
| Alzheimer's disease | Tg(Thy1-APPSweLon)41Ema/0 | involves: C57BL/6 * DBA/2 | J:162842 | View | ||||
| Alzheimer's disease | Tg(Thy1-MAPT)1Vln/Tg(Thy1-MAPT)1Vln | involves: FVB | J:100972, J:100971 | View | ||||
| Alzheimer's disease | Tg(Thy1-MAPT)2Vln/Tg(Thy1-MAPT)2Vln | involves: FVB | J:100972, J:100971 | View | ||||
| Alzheimer's disease | Tg(Thy1-MAPT)22Schd/0 | B6.Cg-Tg(Thy1-MAPT)22Schd | J:111982 | View | ||||
| Alzheimer's disease | Tg(Thy1-MAPT)22Schd/0 | involves: C57BL/6 * CBA | J:197067 | View | ||||
| Alzheimer's disease | Tg(Thy1-MAPT*P301L)2Vln/Tg(Thy1-MAPT*P301L)2Vln | FVB/N-Tg(Thy1-MAPT*P301L)2Vln | J:96869 | View | ||||
| Alzheimer's disease | Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte | involves: C57BL/6 * CBA | J:155410 | View | ||||
| Alzheimer's disease 3 |
Tg(APP695)3Dbo/0 Tg(PSEN1dE9)S9Dbo/0 |
B6.Cg-Tg(APP695)3Dbo Tg(PSEN1dE9)S9Dbo/Mmjax | J:157228 | View | ||||
| Alzheimer's disease 3 |
Tg(APP695)3Dbo/0 Tg(PSEN1dE9)S9Dbo/0 |
involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ * C57BL/6J | J:123534 | View | ||||
| Alzheimer's disease 3 |
Tg(APP695)3Dbo/0 Tg(PSEN1dE9)S9Dbo/0 |
involves: C3H/HeJ * C57BL/6J | J:123534 | View | ||||
| Alzheimer's disease 3 | Tg(APPswe,PSEN1dE9)85Dbo/0 | B6;C3-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax | J:113199 | View | ||||
| Alzheimer's disease 3 | Tg(APPswe,PSEN1dE9)85Dbo/0 | involves: C3H/HeJ * C57BL/6J | J:87691, J:113200 | View | ||||
| Alzheimer's disease 3 | Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0 | involves: C57BL/6 * SJL | J:112949 | View | ||||
| Alzheimer's disease 3 | Tg(PSEN1dE9)S9Dbo/0 | involves: C3H/HeJ * C57BL/6J | J:104147 | View | ||||
| Alzheimer's disease 3 | Tg(PSEN1H163R)G9Btla/0 | involves: 129S4/SvJae | J:58050 | View | ||||
| Alzheimer's disease 4 | Tg(APP695)3Dbo/0 | B6.C3-Tg(APP695)3Dbo | J:109847 | View | ||||
| Alzheimer's disease 4 |
Tg(APP695)3Dbo/0 Tg(PSEN1)5Dbo/0 |
involves: C3H/HeJ * C57BL/6J | J:43788 | View | ||||
| Alzheimer's disease 4 |
Tg(APP695)3Dbo/0 Tg(PSEN1dE9)S9Dbo/0 |
involves: C3H/HeJ * C57BL/6J | J:123534 | View | ||||
| Additional Complex Models | Alzheimer's disease |
Hprt1tm1(Camk2a-APP*Swe*Lon,-MAPT*P301L*R406W)Geno/Hprt1+ Tg(PSEN1)5Dbo/0 |
involves: 129P2/OlaHsd | J:180977 | View | |||
| Alzheimer's disease |
Tg(Camk2a-tTA)1Mmay/0 Fgf14Tg(tetO-MAPT*P301L)4510Kha/Fgf14+ |
involves: FVB/N | J:102973 | View | ||||
| Alzheimer's disease |
Tg(Camk2a-tTA)1Mmay/? Fgf14Tg(tetO-MAPT*P301L)4510Kha/? |
involves: 129S6/SvEvTac * FVB/N | J:99626 | View | ||||
| Alzheimer's disease |
Tg(CMV-IghvaD11)DCat/0 Tg(CMV-IgkvaD11)ACat/0 |
involves: C57BL/6 * SJL | J:62713 | View | ||||
| Alzheimer's disease |
Tg(Gfap-TGFB1)64Lms/0 Zbtb20Tg(PDGFB-APPSwInd)20Lms/0 |
involves: BALB/c * C57BL/6 * DBA/2 * SJL | J:167619 | View | ||||
| Alzheimer's disease |
Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz/0 Tg(Thy1-MAPT)183Gotz/0 |
B6.Cg-Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz Tg(Thy1-MAPT)183Gotz | J:154968 | View | ||||
| Alzheimer's disease |
Trib2Tg(Thy1-Trh/APP*)2.1Ingm/Trib2+ Tg(Thy1-APP*)2.2Ingm/0 |
involves: C57BL/6 * DBA/1 | J:176575 | View | ||||
| Alzheimer's disease | Trib2Tg(Thy1-Trh/APP*)2.1Ingm/Trib2Tg(Thy1-Trh/APP*)2.1Ingm | involves: C57BL/6 * DBA/1 | J:176575 | View | ||||
| Alzheimer's disease | Zbtb20Tg(PDGFB-APPSwInd)20Lms/0 | involves: C57BL/6 * DBA/2 | J:62290 | View | ||||
| Alzheimer's disease 3 |
Tg(APP695)3Dbo/0 Tg(PSEN1)5Dbo/0 |
involves: C3H/HeJ * C57BL/6J | J:43788 | View | ||||
|
No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | Alzheimer's disease | Apba2tm1Tsuz/Apba2tm1Tsuz | C57BL/6-Apba2tm1Tsuz | J:148481 | View | |||
| Alzheimer's disease | Mapttm1Noh/Mapttm1Noh | involves: 129S4/SvJae | J:19030 | View | ||||
| Alzheimer's disease | Psen1tm1Psgh/Psen1tm1Psgh | Not Specified | J:66016 | View | ||||
| Alzheimer's disease 3 | Psen1tm1Psgh/Psen1tm1Psgh | Not Specified | J:66016 | View | ||||