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All mouse models of open-angle glaucoma with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
low tension glaucoma | Optnem1Hyua/Optnem1Hyua | C57BL/6J-Optnem1Hyua | J:303304, J:324291 | View | ||||
open-angle glaucoma | Tg(Myoc*Y423H)#Sit/0 | B6.FVB-Tg(Myoc*Y423H)#Sit | J:116124 | View | ||||
juvenile glaucoma |
Pax6tm2Pgr/Pax6+ Tg(Pax6-cre,GFP)1Pgr/0 |
involves: 129S1/Sv * 129X1/SvJ * FVB | J:163191 | View | ||||
low tension glaucoma | Slc1a1tm1Wst/Slc1a1tm1Wst | B6.129-Slc1a1tm1Wst | J:124191 | View | ||||
low tension glaucoma | Slc1a3tm1Kta/Slc1a3tm1Kta | B6.129P2-Slc1a3tm1Kta | J:124191 | View | ||||
low tension glaucoma | Sod1tm1Leb/Sod1tm1Leb | B6;129S-Sod1tm1Leb/J | J:181434 | View | ||||
primary open angle glaucoma | Gucy1a1tm1.1Brou/Gucy1a1tm1.1Brou | involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ | J:199535 | View | ||||
Transgenes and Other Mutations | low tension glaucoma | Tg(TBK1)#Andm/0 | B6J.Cg-Tg(TBK1)#Andm | J:241433 | View | |||
low tension glaucoma | Tg(TBK1)#Andm/Tg(TBK1)#Andm | B6J.Cg-Tg(TBK1)#Andm | J:241433 | View | ||||
open-angle glaucoma | Tg(MYOC*Y437H)#Sit/0 | B6.FVB-Tg(MYOC*T437C)#Sit | J:135177 | View | ||||
primary open angle glaucoma | Tg(CMV-MYOC*Y437H)#Vcs/0 | involves: C57BL/6J * SJL/J | J:178254 | View | ||||
primary open angle glaucoma | Tg(OPTN*E50K,-EGFP)1Mde/0 | involves: C57BL/6 * C57BL/6N * SJL | J:222642 | View |