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All mouse models of primary open angle glaucoma with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
juvenile glaucoma |
Pax6tm2Pgr/Pax6+ Tg(Pax6-cre,GFP)1Pgr/0 |
involves: 129S1/Sv * 129X1/SvJ * FVB | J:163191 | View | ||||
primary open angle glaucoma | Gucy1a1tm1.1Brou/Gucy1a1tm1.1Brou | involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ | J:199535 | View | ||||
Transgenes and Other Mutations | primary open angle glaucoma | Tg(CMV-MYOC*Y437H)#Vcs/0 | involves: C57BL/6J * SJL/J | J:178254 | View | |||
primary open angle glaucoma | Tg(OPTN*E50K,-EGFP)1Mde/0 | involves: C57BL/6 * C57BL/6N * SJL | J:222642 | View |