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All mouse models of sarcoma with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
alveolar rhabdomyosarcoma |
Cdkn2atm4Rdp/Cdkn2atm4Rdp Myf6tm1(cre)Mrc/Myf6+ Pax3tm1Mrc/Pax3tm1Mrc |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL | J:93444 | View | ||||
alveolar rhabdomyosarcoma |
Myf6tm1(cre)Mrc/Myf6+ Pax3tm1Mrc/Pax3+ |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL | J:93444 | View | ||||
alveolar rhabdomyosarcoma |
Myf6tm1(cre)Mrc/Myf6+ Pax3tm1Mrc/Pax3tm1Mrc Trp53tm1Brn/Trp53+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL | J:93444 | View | ||||
alveolar rhabdomyosarcoma |
Myf6tm1(cre)Mrc/Myf6+ Pax3tm1Mrc/Pax3tm1Mrc Trp53tm1Brn/Trp53tm1Brn |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL | J:93444 | View | ||||
sarcoma |
Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53tm1Brn |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 | J:125101, J:155389, J:204376 | View | ||||
Additional Complex Models | clear cell sarcoma |
Col1a1tm1(tetO-EWSR1/ATF1)Yasu/Col1a1+ Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+ |
involves: 129S4/SvJae * C57BL/6 | J:194505 | View | |||
embryonal rhabdomyosarcoma |
Cdkn2atm1Cjs/Cdkn2atm1Cjs Tg(CKMM-tTA)A3Rhvh/0 Tg(tetO-Hgf,-EGFP)24Tcre/0 |
involves: 129X1/SvJ * FVB | J:237183 | View | ||||
malignant fibrous histiocytoma |
Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53tm1Brn |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 | J:155389 | View | ||||
rhabdomyosarcoma |
Cdkn2atm1Rdp/Cdkn2atm1Rdp Tg(Mt1-Hgf)19Lmb/0 |
involves: 129/Sv * C57BL/6J * FVB/N * SJL | J:79704 | View | ||||
sarcoma |
Cdkn2atm4Rdp/Cdkn2atm4Rdp Krastm4Tyj/Kras+ |
involves: 129S4/SvJae * C57BL/6 | J:125101 | View | ||||
sarcoma |
Cdkn2atm4Rdp/Cdkn2atm4Rdp Nf1tm1Par/Nf1tm1Par |
involves: 129S1/Sv * 129X1/SvJ | J:234760 | View |