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All mouse models of microcytic anemia with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | alpha thalassemia-X-linked intellectual disability syndrome |
Atrxtm1Rjg/Y Foxg1tm1(cre)Skm/Foxg1+ |
involves: 129P2/OlaHsd * C57BL/6 * FVB/N | J:95953 | View | |||
| alpha thalassemia-X-linked intellectual disability syndrome |
Atrxtm1Rjg/Y Tg(Nes-cre)2472Pick/0 |
involves: 129P2/OlaHsd * C57BL/6 * FVB/N | J:95953 | View | ||||
| alpha thalassemia-X-linked intellectual disability syndrome |
Atrxtm1Rjg/Y Tg(Pax6-cre,GFP)2Pgr/0 |
involves: 129P2/OlaHsd * C57BL/6 * FVB/N | J:145002 | View | ||||
| beta thalassemia |
Ahsptm1.1Mjwe/Ahsp+ Hbb-b1tm1Unc/Hbb-b1+ Hbb-b2tm1Unc/Hbb-b2+ |
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 | J:94421 | View | ||||
| beta thalassemia |
Ahsptm1.1Mjwe/Ahsptm1.1Mjwe Hbb-b1tm1Unc/Hbb-b1+ Hbb-b2tm1Unc/Hbb-b2+ |
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 | J:94421 | View | ||||
| beta thalassemia |
Ahsptm1Mjwe/Ahsp+ Hbb-b1tm1Unc/Hbb-b1+ Hbb-b2tm1Unc/Hbb-b2+ |
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 | J:94421 | View | ||||
| beta thalassemia |
Ahsptm1Mjwe/Ahsptm1Mjwe Hbb-b1tm1Unc/Hbb-b1+ Hbb-b2tm1Unc/Hbb-b2+ |
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 | J:94421 | View | ||||
| beta thalassemia |
Hbatm1(HBA)Tow/Hbatm1(HBA)Tow Hbbtm2(HBG1,HBD,HBB*)Ryan/Hbbtm2(HBG1,HBD,HBB*)Ryan |
Not Specified | J:148521 | View | ||||
| beta thalassemia |
Hbatm1(HBA)Tow/Hbatm1(HBA)Tow Hbbtm2(HBG1,HBD,HBB*)Ryan/Hbbtm3(HBG1,HBB)Tow |
Not Specified | J:148521 | View | ||||
| beta thalassemia | Hbb-b1MommeD7/Hbb-b1MommeD7 | involves: FVB/N | J:190446 | View | ||||
| beta thalassemia | Hbb-b1Rbc13/Hbb-b1Rbc13 | involves: BALB/c * C57BL/6 | J:190446 | View | ||||
| beta thalassemia |
Hbb-b1tm1Unc/Hbb-b1+ Hbb-b2tm1Unc/Hbb-b2+ |
B6;129-Hbb-b1tm1Unc Hbb-b2tm1Unc/J | J:211331 | View | ||||
| beta thalassemia |
Hbb-b1tm1Unc/Hbb-b1+ Hbb-b2tm1Unc/Hbb-b2+ |
involves: 129P2/OlaHsd | J:154187 | View | ||||
| beta thalassemia |
Hbb-b1tm1Unc/Hbb-b1+ Hbb-b2tm1Unc/Hbb-b2+ |
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 | J:94421 | View | ||||
| beta thalassemia |
Hbb-b1tm1Unc/Hbb-b1+ Hbb-b2tm1Unc/Hbb-b2+ |
involves: 129P2/OlaHsd * C57BL/6J | J:30155 | View | ||||
| beta thalassemia |
Hbb-b1tm1Unc/Hbb-b1+ Hbb-b2tm1Unc/Hbb-b2+ |
involves: 129P2/OlaHsd * C57BL/6N | J:185154 | View | ||||
| beta thalassemia |
Hbb-b1tm1Unc/Hbb-b1+ Hbb-b2tm1Unc/Hbb-b2+ Tg(HBB*)L2Pai/0 |
involves: 129P2/OlaHsd * C57BL/6 | J:97548 | View | ||||
| beta thalassemia | Hbbd3th/Hbbd3th | involves: C57BL/6 * DBA/2J | J:7209 | View | ||||
| beta thalassemia | Hbbtm1.1(HBG1,HBB*)Ryan/Hbb+ | involves: C57BL/6J | J:147906 | View | ||||
| beta thalassemia | Hbbtm2Unc/Hbb+ | involves: 129P2/OlaHsd * C57BL/6J | J:64295 | View | ||||
| | beta thalassemia | Klf1tm1Sho/Klf1tm1Sho | involves: 129S4/SvJae * C57BL/6 | J:25651 | View | |||
| microcytic anemia | Dnm2Rbc12/Dnm2+ | involves: C57BL/6 | J:330452 | View | ||||
| thalassemia | Ppp1r15atm1.1Ajf/Ppp1r15atm1.1Ajf | involves: 129 * C57BL/6 | J:106905 | View | ||||
| | alpha thalassemia | Hbab2(th)/Hba+ | either: (involves: 101 * SEC) or (involves: 101 * C57BL * SEC) | J:123943 | View | |||
| alpha thalassemia | Hbab2(th)/Hba+ | involves: C57BL/6J * SEC | J:32654 | View | ||||
| alpha thalassemia | Hbab2(th)/Hba+ | SEC-Hbab2(th) | J:6452 | View | ||||
| alpha thalassemia | Hbab3(th)/Hba+ | either: (involves: 101 * SEC) or (involves: 101 * C57BL * SEC) | J:123943 | View | ||||
| alpha thalassemia | Hbab3(th)/Hba+ | involves: C57BL/6J * SEC | J:32654 | View | ||||
| alpha thalassemia | Hbab3(th)/Hba+ | SEC-Hbab3(th) | J:6452 | View | ||||
| alpha thalassemia | Hbath-J/Hba+ | involves: C57BL/6J | J:45721, J:32654 | View | ||||
| Transgenes and Other Mutations | alpha thalassemia | Hbatm1Ney/Hbatm1Ney | either: (involves: 129P2/OlaHsd) or (involves: 129X1/SvJ) | J:86682 | View | |||
| beta thalassemia | Hbbtm1Unc/Hbbtm1Unc | involves: 129P2/OlaHsd * C57BL/6J | J:4932 | View | ||||
| beta thalassemia | Rr320tm1.1Mkg/Rr320+ | involves: 129 | J:60714 | View | ||||
| beta thalassemia | Rr320tm2Mkg/Rr320tm2Mkg | involves: 129S4/SvJaeSor | J:28981 | View | ||||
| Additional Complex Models | hypochromic microcytic anemia |
Eps15tm1c(KOMP)Wtsi/Eps15tm1c(KOMP)Wtsi Eps15l1tm2.1Noff/Eps15l1tm2.1Noff Tg(Tek-cre)1Ywa/0 |
involves: C57BL/6 * C57BL/6N * SJL | J:272122 | View | |||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | beta thalassemia | Del(7Or2h1-Rr320)1Mkg/+ | involves: 129 | J:139198 | View | |||