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All mouse models of megacolon with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
Hirschsprung's disease | Edn3ls/Edn3ls | involves: C57BL | J:5008 | View | ||||
Hirschsprung's disease | Edn3tm1Ywa/Edn3tm1Ywa | involves: 129S7/SvEvBrd | J:22207 | View | ||||
Hirschsprung's disease | Ednrbs-l/Ednrbs-l | involves: C3H/HeJ * C57BL/6 | J:5008 | View | ||||
Hirschsprung's disease | Ednrbtm1.1Nrd/Ednrbtm1.1Nrd | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:226561 | View | ||||
Hirschsprung's disease |
Ednrbtm1Nrd/Ednrbtm1Nrd Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ H2az2Tg(Wnt1-cre)11Rth/H2az2+ |
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA/J | J:233811 | View | ||||
Hirschsprung's disease | Ednrbtm1Ywa/Ednrbtm1Ywa | B6;129-Ednrbtm1Ywa/J | J:216833 | View | ||||
Hirschsprung's disease | Ednrbtm1Ywa/Ednrbtm1Ywa | involves: 129S5/SvEvBrd | J:93622 | View | ||||
Hirschsprung's disease | Gdnftm1Lmgd/Gdnf+ | either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6) or (involves: 129/Sv * CD-1) | J:73922 | View | ||||
Hirschsprung's disease | Gdnftm1Lmgd/Gdnftm1Lmgd | either: (involves: 129S4/SvJae) or (involves: 129S1/Sv * 129X1/SvJ) | J:33810 | View | ||||
Hirschsprung's disease | Gdnftm1Rosl/Gdnf+ | involves: 129S2/SvPas * C57BL/6 | J:82456 | View | ||||
Hirschsprung's disease | Rettm1Cos/Rettm1Cos | involves: 129S/Sv * C57BL/6 | J:135153 | View | ||||
Hirschsprung's disease | Rettm1Cos/Rettm1Cos | involves: 129S/SvEv * MF1 | J:23852, J:30389 | View | ||||
Hirschsprung's disease | Rettm1Cos/Rettm2(RET)Jmi | involves: 129S/Sv * C57BL/6 | J:135153 | View | ||||
Hirschsprung's disease | Rettm2.1Heno/Rettm2.1Heno | involves: 129S/Sv * C57BL/6 * FVB/N | J:135153 | View | ||||
Hirschsprung's disease | Aebp2Gt(BC0681)Wtsi/Aebp2+ | involves: 129P2/OlaHsd * C57BL/6 | J:177673 | View | ||||
Hirschsprung's disease |
Erbb2tm1Klee/Erbb2tm1Klee Tg(Nes-cre)1Atp/0 |
involves: C57BL/6 * FVB/N | J:81239 | View | ||||
Hirschsprung's disease | Gfra1tm1Jmi/Gfra1tm1Jmi | involves: 129X1/SvJ * C57BL/6 | J:49471 | View | ||||
Hirschsprung's disease |
Gfra1tm1Jmi/Gfra1tm2Jmi Tg(CAG-cre/Esr1*)5Amc/0 |
involves: 129/Sv * C57BL/6 * CBA * SJL | J:122607 | View | ||||
Hirschsprung's disease | Ihhtm1Amc/Ihhtm1Amc | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J | J:62158 | View | ||||
Hirschsprung's disease |
Itgb1tm1Lscd/Itgb1tm1Ref Tg(PLAT-cre)116Sdu/0 |
involves: 129S1/Sv * 129X1/SvJ | J:108439 | View | ||||
Transgenes and Other Mutations | Hirschsprung's disease | Tg(Sox3-GFP,Tyr)HolNpln/Tg(Sox3-GFP,Tyr)HolNpln | involves: FVB/N | J:229828 | View | |||
Hirschsprung's disease | Tg(SRY-YFP,Tyr)TashTNpln/Tg(SRY-YFP,Tyr)TashTNpln | involves: FVB/N | J:224231 | View |