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All mouse models of familial hyperlipidemia with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | autosomal recessive hypercholesterolemia | Ldlrap1Gt(OST149604)Lex/Ldlrap1Gt(OST149604)Lex | involves: 129S5/SvEvBrd * C57BL/6 | J:102291 | View | |||
| autosomal recessive hypercholesterolemia | Ldlrap1tm1Her/Ldlrap1tm1Her | involves: 129S6/SvEvTac | J:84694 | View | ||||
| familial hypercholesterolemia |
Apobec1tm1Ddsn/Apobec1tm1Ddsn Ldlrtm1Her/Ldlrtm1Her |
involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 | J:49125 | View | ||||
| familial hypercholesterolemia | LdlrHlb301/Ldlr+ | C57BL/6J-LdlrHlb301/J | J:82961 | View | ||||
| familial hypercholesterolemia | LdlrHlb301/LdlrHlb301 | C57BL/6J-LdlrHlb301/J | J:82961 | View | ||||
| familial hypercholesterolemia | Ldlrtm1Her/Ldlrtm1Her | involves: 129S7/SvEvBrd | J:84694 | View | ||||
| familial hypercholesterolemia | Ldlrtm1Her/Ldlrtm1Her | involves: 129S7/SvEvBrd * C57BL/6 | J:102291 | View | ||||
| familial hypercholesterolemia |
Ldlrtm1Her/Ldlrtm1Her Lepob/Lepob |
B6.Cg-Lepob Ldlrtm1Her | J:72027 | View | ||||
| familial hypercholesterolemia |
Ldlrtm1Her/Ldlrtm1Her Tg(Il1rn)1Dih/Tg(Il1rn)1Dih |
involves: 129S7/SvEvBrd * C57BL/6 * CBA | J:76336 | View | ||||
| familial lipoprotein lipase deficiency | Lpltm1Bres/Lpl+ | involves: 129S4/SvJae * C57BL/6J | J:30062 | View | ||||
| familial lipoprotein lipase deficiency | Lpltm1Bres/Lpltm1Bres | involves: 129S4/SvJae * C57BL/6J | J:30062 | View | ||||
| familial lipoprotein lipase deficiency | Lpltm1Sem/Lpl+ | involves: 129P2/OlaHsd * C57BL/6J | J:25652 | View | ||||
| familial lipoprotein lipase deficiency | Lpltm1Sem/Lpltm1Sem | involves: 129P2/OlaHsd * C57BL/6J | J:25652 | View | ||||
| | familial combined hyperlipidemia |
Apoetm1Unc/Apoetm1Unc Lpltm1Sem/Lpltm1Sem |
involves: 129P2/OlaHsd | J:151434 | View | |||
| Additional Complex Models | familial combined hyperlipidemia |
Ldlrtm1Her/Ldlrtm1Her Tg(APOC3)3707Bres/? |
involves: 129S7/SvEvBrd * C57BL/6J * CBA/J | J:37861 | View | |||
| familial hypercholesterolemia | Gt(ROSA)26Sortm1.1(Alb-PCSK9)Mby/Gt(ROSA)26Sor+ | involves: C57BL/6 * C57BL/6N | J:280156 | View | ||||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | familial combined hyperlipidemia | Tnfrsf1btm1Imx/Tnfrsf1btm1Imx | involves: 129S7/SvEvBrd * C57BL/6 | J:45147 | View | |||