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All mouse models of hypertrophic cardiomyopathy with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | hypertrophic cardiomyopathy | Csrp3tm1.1Kage/Csrp3tm1.1Kage | involves: C57BL/6 * C57BL/6J * C57BL/6N * SJL | J:307893 | View | |||
| hypertrophic cardiomyopathy 2 | Tg(Myh6-Tnnt2)117Lnwd/0 | involves: C57BL/6 | J:48301 | View | ||||
| hypertrophic cardiomyopathy 2 | Tg(Myh6-Tnnt2)191Lnwd/0 | involves: C57BL/6 | J:48301 | View | ||||
| hypertrophic cardiomyopathy 2 | Tg(Myh6-Tnnt2*R92L)1Jcf/0 | B6.Cg-Tg(Myh6-Tnnt2*R92L)1Jcf | J:104369 | View | ||||
| hypertrophic cardiomyopathy 2 | Tg(Myh6-Tnnt2*R92Q)2Lnwd/0 | involves: C57BL/6 | J:56911 | View | ||||
| hypertrophic cardiomyopathy 2 | Tg(Myh6-Tnnt2*R92W)1Jcf/0 | B6.Cg-Tg(Myh6-Tnnt2*R92W)1Jcf | J:104369 | View | ||||
| hypertrophic cardiomyopathy 3 | Tg(Myh6-Tpm1*D175N)#Dfw/0 | Not Specified | J:57365 | View | ||||
| hypertrophic cardiomyopathy 3 | Tg(Myh6-Tpm1*E180G)57Dfw/0 | involves: FVB/N | J:127507, J:172340, J:171021 | View | ||||
| hypertrophic cardiomyopathy 4 | Mybpc3tm1.1Jse/Mybpc3tm1.1Jse | Not Specified | J:58295 | View | ||||
| hypertrophic cardiomyopathy 4 | Mybpc3tm1Jse/Mybpc3tm1Jse | Not Specified | J:58295 | View | ||||
| hypertrophic cardiomyopathy 4 | Mybpc3tm1Lcrr/Mybpc3+ | involves: 129S4/SvJae * Black Swiss | J:101903 | View | ||||
| hypertrophic cardiomyopathy 4 | Mybpc3tm1Rmos/Mybpc3tm1Rmos | either: (involves: 129) or (involves: 129 * C57BL/6) | J:95725 | View | ||||
| hypertrophic cardiomyopathy 4 | Mybpc3tm2.1Lcrr/Mybpc3+ | involves: 129S2/SvPasCrl * Black Swiss | J:185726 | View | ||||
| hypertrophic cardiomyopathy 4 | Mybpc3tm2.1Lcrr/Mybpc3tm2.1Lcrr | involves: 129S2/SvPasCrl * Black Swiss | J:185726 | View | ||||
| hypertrophic cardiomyopathy 4 | Tg(Myh6-Mybpc3*)24Rbns/0 | Not Specified | J:59702 | View | ||||
| hypertrophic cardiomyopathy 4 | Tg(Myh6-Mybpc3*)32Rbns/0 | Not Specified | J:50237, J:127656 | View | ||||
| hypertrophic cardiomyopathy 7 | Tg(Myh6-Tnni3*L184)#Rste/0 | B6.Cg-Tg(Myh6-Tnni3*L184)#Rste | J:161911 | View | ||||
| hypertrophic cardiomyopathy 7 | Tg(Myh6-Tnni3*R146G)121Rbns/0 | Not Specified | J:243628 | View | ||||
| hypertrophic cardiomyopathy 7 | Tg(Myh6-Tnni3*R146G)133Rbns/0 | Not Specified | J:243628 | View | ||||
| hypertrophic cardiomyopathy 12 | Csrp3tm1.1Rkn/Csrp3tm1.1Rkn | either: (involves: Black Swiss) or (involves: C57BL/6N) | J:170878 | View | ||||
| hypertrophic cardiomyopathy 13 | Tnnc1tm1.1Jrpi/Tnnc1+ | involves: 129S6/SvEvTac * C57BL/6 | J:274007 | View | ||||
| hypertrophic cardiomyopathy 13 | Tnnc1tm1.1Jrpi/Tnnc1tm1.1Jrpi | involves: 129S6/SvEvTac * C57BL/6 | J:274007, J:249978 | View | ||||
| hypertrophic cardiomyopathy 14 | Myh6tm1.1Jpsc/Myh6tm2Jse | involves: 129 | J:247162 | View | ||||
| hypertrophic cardiomyopathy 14 | Myh6tm1Jse/Myh6+ | 129S.129X1-Myh6tm1Jse | J:104363 | View | ||||
| hypertrophic cardiomyopathy 14 | Myh6tm1Jse/Myh6+ | involves: 129X1/SvJ | J:32960, J:95600 | View | ||||
| hypertrophic cardiomyopathy 14 | Myh6tm2Jse/Myh6+ | involves: 129 | J:247162 | View | ||||
| hypertrophic cardiomyopathy 14 | Myh6tm2Jse/Myh6+ | involves: 129S1/Sv | J:95600 | View | ||||
| hypertrophic cardiomyopathy 14 | Myh6tm3.1Jse/Myh6+ | involves: 129 | J:247162 | View | ||||
| hypertrophic cardiomyopathy 14 | Myh6tm3.1Jse/Myh6+ | involves: 129X1/SvJ | J:165269 | View | ||||
| hypertrophic cardiomyopathy 20 | Nexntm1.1Zhh/Nexntm1.1Zhh | involves: C57BL/6NTac | J:228046 | View | ||||
| | hypertrophic cardiomyopathy | Cav1tm1Mls/Cav1tm1Mls | involves: 129/Sv * C57BL/6 * SJL | J:87282 | View | |||
| hypertrophic cardiomyopathy | Pepddal/Pepddal | involves: C3H/HeJ * CBA/J | J:215150 | View | ||||
| hypertrophic cardiomyopathy | Pkd1b2b1585Clo/Pkd1b2b1585Clo | C57BL/6J-Pkd1b2b1585Clo | J:175213 | View | ||||
| hypertrophic cardiomyopathy | Tg(Ckmm-Cav3)1Ysu/0 | involves: C57BL/Slc * DBA/Slc | J:87692 | View | ||||
| hypertrophic cardiomyopathy | Tg(Myh6-Htr2b)1Lum/0 | involves: CD-1 | J:128784 | View | ||||
| hypertrophic cardiomyopathy | Tg(Myh6-Mtpn)4Ssen/0 | involves: FVB | J:89823 | View | ||||
| hypertrophic cardiomyopathy | Tg(Myh7-Ptpn11*Q510E)#Krnz/0 | FVB/N-Tg(Myh7-Ptpn11*Q510E)#Krnz | J:181656 | View | ||||
| hypertrophic cardiomyopathy | Xirp1tm1Jl/Xirp1tm1Jl | involves: 129 | J:132079 | View | ||||
| | hypertrophic cardiomyopathy |
Mybpc3DBA/2J/Mybpc3DBA/2J Myh7DBA/2J/Myh7DBA/2J |
DBA/2J | J:225492 | View | |||
| hypertrophic cardiomyopathy 16 |
Myoz2tm1Eno/Myoz2+ Tg(Myh6-MYOZ2*I246M)#Ajm/0 |
involves: 129/Sv * FVB/N | J:210073 | View | ||||
| Transgenes and Other Mutations | hypertrophic cardiomyopathy | Tg(Myh6-CACNA1C)M1Aschw/0 | involves: FVB/N | J:134761 | View | |||
| hypertrophic cardiomyopathy | Tg(Myh6-Erbb2)6Kaga/0 | involves: C57BL/6J * SJL/J | J:189979 | View | ||||
| hypertrophic cardiomyopathy | Tg(Myh6-MYPN*Y20C)#Jato/0 | involves: C57BL/6J | J:181871 | View | ||||
| hypertrophic cardiomyopathy |
Tg(Myh6-rtTA)8585Jam/0 Tg(tetO-Fgfr3*R248C/Fgfr1)#Dor/0 |
involves: 129 * C57BL/6 * FVB/N * FVB/NTac | J:211151 | View | ||||
| hypertrophic cardiomyopathy 2 | Tg(Myh6-TNNT2*I79N)8Jdp/0 | involves: C57BL/6 * SJL | J:213305 | View | ||||
| hypertrophic cardiomyopathy 2 | Tg(Myh6-TNNT2*R92Q)#Ajm/0 | involves: C3H * C57BL/6 * ICR | J:162685, J:161899 | View | ||||
| hypertrophic cardiomyopathy 2 | Tg(Tnnt2-TNNT2*R92Q)#Ajm/0 | involves: C3H * C57BL/6 * ICR | J:117554 | View | ||||
| hypertrophic cardiomyopathy 2 | Tg(Tnnt2-TNNT2*R92Q)M-2Ajm/0 | involves: C3H * C57BL/6 * ICR | J:117554 | View | ||||
| hypertrophic cardiomyopathy 4 |
Tg(Myh6/tetO-Mybpc3*)#Rbns/0 Tg(Myh6-tTA)55Rbns/0 |
involves: FVB/N | J:213370 | View | ||||
| hypertrophic cardiomyopathy 6 | Tg(Myh6-PRKAG2*N488I)4623Jse/0 | involves: FVB | J:128648 | View | ||||
| hypertrophic cardiomyopathy 7 | Tg(Myh6-TNNI3*G203S)1Chs/0 | Not Specified | J:114537 | View | ||||
| hypertrophic cardiomyopathy 7 | Tg(Myh6-TNNI3*G203S)4Chs/0 | Not Specified | J:114537 | View | ||||
| hypertrophic cardiomyopathy 8 | Tg(Myh6-MYL3*A57G)#Dsc/0 | involves: C57BL/6 * SJL | J:202154 | View | ||||
| hypertrophic cardiomyopathy 10 | Tg(Myh6-MYL2*A13T)L1Dsc/0 | involves: C57BL/6 * SJL | J:181028 | View | ||||
| hypertrophic cardiomyopathy 10 | Tg(Myh6-MYL2*D166V)1Dsc/0 | involves: C57BL/6 * SJL | J:146091 | View | ||||
| hypertrophic cardiomyopathy 10 | Tg(Myh6-MYL2*E22K)4Dsc/0 | involves: C57BL/6 * SJL | J:101467 | View | ||||
| hypertrophic cardiomyopathy 10 | Tg(Myh6-MYL2*K104E)2Dsc/0 | involves: C57BL/6 * SJL | J:263776 | View | ||||
| hypertrophic cardiomyopathy 10 | Tg(Myh6-MYL2*N47K)#Dsc/0 | involves: C57BL/6 * SJL | J:162200 | View | ||||
| hypertrophic cardiomyopathy 10 | Tg(Myh6-MYL2*R58Q)#Dsc/0 | involves: C57BL/6 * SJL | J:162200 | View | ||||
| hypertrophic cardiomyopathy 11 | Tg(Myh6-ACTC1*E99K)#Sbm/0 | involves: C57BL/10 * CBA/Ca | J:175388 | View | ||||
| hypertrophic cardiomyopathy 14 | Tg(Myh6*)1Lnwd/0 | involves: C57BL/6 * FVB/N | J:55938 | View | ||||
| hypertrophic cardiomyopathy 14 | Tg(Myh6*)1Lnwd/Tg(Myh6*)1Lnwd | involves: C57BL/6 * FVB/N | J:55938 | View | ||||
| hypertrophic cardiomyopathy 14 | Tg(Myh6*)131Lnwd/0 | involves: C57BL/6 * CBA | J:31537 | View | ||||
| hypertrophic cardiomyopathy 14 | Tg(Myh6*)140Lnwd/0 | involves: C57BL/6 * CBA | J:31537, J:36522 | View | ||||
| hypertrophic cardiomyopathy 16 | Tg(Myh6-MYOZ2*I246M)#Ajm/0 | involves: FVB | J:210073 | View | ||||
| hypertrophic cardiomyopathy 16 | Tg(Myh6-MYOZ2*S48P)114Ajm/0 | involves: FVB | J:210073 | View | ||||
| Additional Complex Models | hypertrophic cardiomyopathy |
Myh6tm1Jse/Myh6+ Tg(Myh6-TNNI3*G203S)1Chs/0 |
involves: 129X1/SvJ * C57BL/6 | J:153302 | View | |||
| hypertrophic cardiomyopathy |
Nos1tm1Plh/Nos1tm1Plh Nos3tm1Plh/Nos3tm1Plh |
B6.129S4-Nos3tm1Plh Nos1tm1Plh | J:129064 | View | ||||
| hypertrophic cardiomyopathy |
Nos1tm1Plh/Nos1tm1Plh Nos3tm1Plh/Nos3tm1Plh |
involves: 129S4/SvJae * C57BL/6 | J:129064 | View | ||||