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All mouse models of female reproductive organ cancer with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
ovarian cancer |
Amhr2tm3(cre)Bhr/Amhr2+ Ctnnb1tm1Mmt/Ctnnb1+ |
involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 | J:186144 | View | ||||
ovarian cancer |
Amhr2tm3(cre)Bhr/Amhr2+ Ctnnb1tm1Mmt/Ctnnb1+ Ptentm1Hwu/Ptentm1Hwu |
involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 | J:186144 | View | ||||
ovarian cancer |
Ctnnb1tm1Mmt/Ctnnb1+ Krastm4Tyj/Kras+ Amhr2tm3(cre)Bhr/Amhr2+ |
involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 | J:186144 | View | ||||
ovarian cancer |
Ctnnb1tm1Mmt/Ctnnb1+ Krastm4Tyj/Kras+ Tg(CYP19A1-cre)1Jri/0 |
involves: 129S4/SvJae * 129X1/SvJ * C57BL/6 | J:186144 | View | ||||
ovarian cancer |
Ctnnb1tm1Mmt/Ctnnb1+ Ptentm1Hwu/Ptentm1Hwu Tg(CYP19A1-cre)1Jri/0 |
involves: 129S4/SvJae * 129X1/SvJ * C57BL/6 | J:186144 | View | ||||
ovarian cancer |
Ctnnb1tm1Mmt/Ctnnb1+ Tg(CYP19A1-cre)1Jri/0 |
involves: 129X1/SvJ * C57BL/6 | J:186144 | View | ||||
endometrial cancer |
Errfi1tm1Jwj/Errfi1tm1Jwj Pgrtm2(cre)Lyd/Pgr+ |
involves: 129S1/Sv * 129X1/SvJ | J:150007 | View | ||||
endometrial cancer |
Errfi1tm1Jwj/Errfi1tm1Jwj Pgrtm2(cre)Lyd/Pgr+ Ptentm1Hwu/Ptentm1Hwu |
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ | J:162027 | View | ||||
endometrial cancer |
Pgrtm2(cre)Lyd/Pgr+ Ptentm1Hwu/Ptentm1Hwu |
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 | J:139053 | View | ||||
endometrial cancer |
Pgrtm2(cre)Lyd/Pgr+ Ptentm1Hwu/Ptentm1Hwu Trp53tm1Brn/Trp53tm1Brn |
involves: 129 * C57BL/6 | J:139053 | View | ||||
endometrial cancer |
Stk11tm1.1Rdp/Stk11tm1.1Rdp Tg(Sprr2f-cre)1Dcas/0 |
involves: 129S6/SvEvTac * FVB/N | J:158190 | View | ||||
endometrial cancer |
Trp53tm1Brn/Trp53tm1Brn Tg(Cdh16-cre)91Igr/0 |
involves: 129P2/OlaHsd * C57BL/6J * FVB/N * ICR | J:214850 | View | ||||
ovarian cancer |
Apctm1Rsmi/Apctm1Rsmi Pgrtm2(cre)Lyd/Pgr+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J | J:210095 | View | ||||
ovarian cancer |
Apctm1Tno/Apctm1Tno Ptentm2Mak/Ptentm2Mak |
involves: 129P2/OlaHsd * 129S4/SvJae | J:120955 | View | ||||
uterine cancer | Tg(H2-K-Hmga1)#Lmsr/0 | involves: C57BL/6 * SJL | J:121308 | View | ||||
ovarian cancer |
Arid1atm1.1Mag/Arid1atm1.1Mag Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/Gt(ROSA)26Sor+ |
involves: 129S6/SvEvTac * CD-1 | J:219794 | View | ||||
ovarian cancer |
Brca1tm1Brn/Brca1tm1Brn Tg(Krt18-EGFP,-TAg121)36Ysng/0 Trp53tm1Brn/Trp53tm1Brn |
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N | J:189304 | View | ||||
ovarian cancer |
Brca1tm1Brn/Brca1tm1Brn Tg(Krt18-EGFP,-TAg121)36Ysng/0 Trp53tm1Brn/Trp53tm2Tyj |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N | J:189304 | View | ||||
ovarian cancer |
Brca2tm1Brn/Brca2tm1Brn Tg(Krt18-EGFP,-TAg121)36Ysng/0 Trp53tm1Brn/Trp53tm2Tyj |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N | J:189304 | View | ||||
ovarian cancer |
Dicer1tm1Tara/Dicer1tm1Tara Ptentm1Hwu/Ptentm1Hwu Amhr2tm3(cre)Bhr/Amhr2+ |
involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd | J:182161 | View | ||||
ovarian cancer |
Dicer1tm1Tara/Dicer1tm1Tara Ptentm1Hwu/Ptentm1Hwu Trp53tm2Tyj/Trp53+ Amhr2tm3(cre)Bhr/Amhr2+ |
involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd | J:222579 | View | ||||
ovarian cancer |
Krastm4Tyj/Kras+ Ptentm1Hwu/Ptentm1Hwu |
involves: 129S4/SvJae | J:161953 | View | ||||
ovarian cancer |
Krastm4Tyj/Kras+ Ptentm1Hwu/Ptentm1Hwu |
involves: 129S4/SvJae * C57BL/6J | J:96296 | View | ||||
ovarian cancer |
Ptentm1Hwu/Ptentm1Hwu Trp53tm2Tyj/Trp53+ Amhr2tm3(cre)Bhr/Amhr2+ |
involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd | J:222579 | View | ||||
Transgenes and Other Mutations | ovarian cancer | Tg(Amhr2-SV40TAg)1Dcco/0 | (C57BL/6 x C3H)F1 | J:82550 | View | |||
ovarian cancer | Tg(CAG-lacZ,-SV40)#Bcv/0 | involves: FVB/N | J:158388 | View | ||||
Additional Complex Models | ovarian cancer |
Amhr2tm3(cre)Bhr/Amhr2+ Smad1tm2Rob/Smad1tm2.1Rob Smad5tm1Huy/Smad5tm1Huy |
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J | J:157310 | View | |||
ovarian cancer |
Amhr2tm3(cre)Bhr/Amhr2+ Smad1tm2Rob/Smad1tm2Rob Smad5tm1Huy/Smad5tm1Huy |
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J | J:157310 | View | ||||
ovarian cancer |
Amhr2tm3(cre)Bhr/Amhr2+ Smad1tm2Rob/Smad1tm2Rob Smad5tm1Huy/Smad5tm1Zuk |
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J | J:157310 | View | ||||
ovarian cancer |
Cdkn1btm1Ako/Cdkn1b+ KitW-v/KitW-v |
involves: 129S1/Sv * C57BL/6J | J:236161 | View | ||||
ovarian cancer |
Cdkn1btm1Ako/Cdkn1btm1Ako KitW-v/KitW-v |
involves: 129S1/Sv * C57BL/6J | J:236161 | View | ||||
ovarian cancer |
Foxo1tm1Rdp/Foxo1tm1.1Rdp Foxo3tm1Rdp/Foxo3tm1.1Rdp Amhr2tm3(cre)Bhr/Amhr2+ |
involves: 129S6/SvEvTac * 129S7/SvEvBrd | J:232961 | View | ||||
ovarian cancer |
Foxo1tm1Rdp/Foxo1tm1.1Rdp Foxo3tm1Rdp/Foxo3tm1.1Rdp Tg(CYP19A1-cre)1Jri/0 |
involves: 129S6/SvEvTac | J:232961 | View | ||||
ovarian cancer |
KitW-v/KitW-v Trp53tm1Brn/Trp53tm1Brn |
involves: 129P2/OlaHsd * C57BL/6J * FVB/N | J:236161 | View | ||||
ovarian cancer |
Rb1tm2Brn/Rb1tm2Brn Trp53tm1Brn/Trp53tm1Brn |
involves: 129P2/OlaHsd | J:84345 | View | ||||
ovarian cancer |
Tg(Krt18-EGFP,-TAg121)36Ysng/0 Trp53tm1Brn/Trp53tm1Brn |
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N | J:189304 | View | ||||
ovarian cancer |
Tg(Krt18-EGFP,-TAg121)36Ysng/0 Trp53tm1Brn/Trp53tm2Tyj |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N | J:189304 | View |
No similarity to the expected human disease phenotype was found.
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
NOT Models | ovarian cancer | Tg(Amhr2-Pik3ca*,-GFP)#Lzh/0 | involves: C3H * C57BL/6 | J:144834 | View |