 Excel File
Text File
All mouse models of Huntington's disease with phenotypic similarity to the human disease
|
||||||||
| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | Huntington's disease | Htttm1.1Pfs/Htt+ | involves: 129S4/SvJae * C57BL/6 | J:54906 | View | |||
| Huntington's disease | Htttm1.1Tna/Htt+ | involves: 129P2/OlaHsd * C57BL/6J | J:76017 | View | ||||
| Huntington's disease | Htttm1.1Tna/Htttm1.1Tna | involves: 129P2/OlaHsd * C57BL/6J | J:76017 | View | ||||
| Huntington's disease | Htttm1Detl/Htt+ | involves: 129P2/OlaHsd * C57BL/6J | J:67074 | View | ||||
| Huntington's disease | Htttm1Detl/Htttm1Detl | involves: 129P2/OlaHsd * C57BL/6J | J:67074 | View | ||||
| Huntington's disease | Htttm1Hay/Htt+ | involves: C57BL/6J | J:25941 | View | ||||
| Huntington's disease |
Htttm1Hay/Htttm1Hay Tg(HTT*97Q)IXwy/0 Tg(YAC18)18Hay/Tg(YAC18)18Hay |
FVB.Cg-Htttm1Hay Tg(HTT*97Q)IXwy Tg(YAC18)18Hay | J:191147, J:215223 | View | ||||
| Huntington's disease |
Htttm1Mem/Htttm6Mem Tg(CAG-cre/Esr1*)5Amc/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * Swiss Webster | J:260244 | View | ||||
| Huntington's disease | Htttm1Mfc/Htttm1Mfc | involves: 129S1/Sv * C57BL/6 | J:85298, J:141673 | View | ||||
| Huntington's disease |
Htttm1Szi/Htttm2Szi Tg(Camk2a-cre)1Szi/0 |
involves: 129S/SvEv * 129S1/Sv * C57BL/6 * CBA | J:65520 | View | ||||
| Huntington's disease |
Htttm1Szi/Htttm2Szi Tg(Camk2a-cre)2Szi/0 |
involves: 129S/SvEv * 129S1/Sv * C57BL/6 * CBA | J:65520 | View | ||||
| Huntington's disease | Htttm2.1Pfs/Htt+ | involves: 129X1/SvJ * C57BL/6 | J:54906 | View | ||||
| Huntington's disease | Htttm2Detl/Htt+ | B6J.129P2-Htttm2Detl | J:220868 | View | ||||
| Huntington's disease | Htttm2Detl/Htttm2Detl | involves: 129P2/OlaHsd * C57BL/6J | J:123681 | View | ||||
| Huntington's disease | Htttm2Msl/Htttm2Msl | involves: 129S1/Sv * C57BL/6J | J:76018, J:79137 | View | ||||
| Huntington's disease | Htttm4Mem/Htt+ | involves: 129S1/Sv * 129X1/SvJ * CD-1 | J:60937 | View | ||||
| Huntington's disease | Htttm4Mem/Htttm4Mem | involves: 129S1/Sv * 129X1/SvJ * CD-1 | J:60937, J:99425, J:111237 | View | ||||
| Huntington's disease | Htttm5Detl/Htt+ | involves: C57BL/6 | J:250587 | View | ||||
| Huntington's disease | Htttm5Mem/Htt+ | involves: 129S1/Sv * 129X1/SvJ * CD-1 | J:60937 | View | ||||
| Huntington's disease | Htttm5Mem/Htttm5Mem | involves: 129S1/Sv * 129X1/SvJ * CD-1 | J:60937, J:99425, J:111237 | View | ||||
| Huntington's disease |
Tg(Camk2a-tTA)1Mmay/0 Tg(tetO-HTT*94Q,-lacZ)1Rhn/0 |
involves: C57BL/6 * CBA | J:61490 | View | ||||
| | Huntington's disease |
Tg(CAG-Ppard*E411P)#Als/0 Tg(Nes-cre)1Kln/0 |
B6J.Cg-Tg(Nes-cre)1Kln Tg(CAG-Ppard*E411P)#Als | J:233176 | View | |||
| Huntington's disease | Zdhhc13Gt(AC0492)Wtsi/Zdhhc13Gt(AC0492)Wtsi | FVB.129P2-Zdhhc13Gt(AC0492)Wtsi | J:191129 | View | ||||
| Huntington's disease | Zdhhc17Gt(RRJ233)Byg/Zdhhc17Gt(RRJ233)Byg | FVB.129P2-Zdhhc17Gt(RRJ233)Byg | J:175800 | View | ||||
| Transgenes and Other Mutations | Huntington's disease |
Cnr1tm1Map/Cnr1tm1Map Tg(HD82Gln)81Gschi/0 |
involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 * CD-1 | J:172874 | View | |||
| Huntington's disease | Tg(CMV-HTT*48Q)BTag/0 | involves: FVB/N | J:50173 | View | ||||
| Huntington's disease | Tg(CMV-HTT*48Q)BTag/Tg(CMV-HTT*48Q)BTag | involves: FVB/N | J:50173 | View | ||||
| Huntington's disease | Tg(CMV-HTT*89Q)ATag/0 | involves: FVB/N | J:50173 | View | ||||
| Huntington's disease | Tg(CMV-HTT*89Q)ATag/Tg(CMV-HTT*89Q)ATag | involves: FVB/N | J:50173 | View | ||||
| Huntington's disease | Tg(GFAP-HTT*160Q)1Xjl/0 | either: (involves: FVB/NCrl) or (involves: C3H * C57BL/6 * FVB/NCrl) | J:156460 | View | ||||
| Huntington's disease | Tg(GFAP-HTT*160Q)31Xjl/0 | either: (involves: FVB/NCrl) or (involves: C3H * C57BL/6 * FVB/NCrl) | J:156460 | View | ||||
| Huntington's disease | Tg(HD82Gln)81Gschi/0 | involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 * CD-1 | J:172874 | View | ||||
| Huntington's disease | Tg(HD82Gln)81Gschi/0 | involves: C3H/HeJ * C57BL/6 | J:53797 | View | ||||
| Huntington's disease | Tg(HD)63Aron/? | involves: C57BL/6 * SJL | J:72772 | View | ||||
| Huntington's disease | Tg(HDexon1)61Gpb/? | involves: C57BL/6 * CBA | J:42085, J:203027 | View | ||||
| Huntington's disease | Tg(HDexon1)62Gpb/0 | B6CBA-Tg(HDexon1)62Gpb/1J | J:99425, J:111237 | View | ||||
| Huntington's disease | Tg(HDexon1)62Gpb/0 | involves: C57BL/6 * CBA | J:42085 | View | ||||
| Huntington's disease | Tg(HDexon1)62Gpb/0 | involves: C57BL/6J * CBA/J | J:36689 | View | ||||
| Huntington's disease | Tg(HTT*97Q)IXwy/0 | FVB-Tg(HTT*97Q)IXwy | J:137345 | View | ||||
| Huntington's disease | Tg(HTT*)1Xwy/0 | FVB-Tg(HTT*)1Xwy | J:157723 | View | ||||
| Huntington's disease | Tg(HTT*)LXwy/0 | involves: FVB/NJ | J:219890 | View | ||||
| Huntington's disease | Tg(HTT*)NXwy/0 | involves: FVB/NJ | J:219890 | View | ||||
| Huntington's disease | Tg(HTT*/EGFP)150Nn/0 | involves: C57BL/6 * DBA/2 | J:174269 | View | ||||
| Huntington's disease | Tg(HTT*/EGFP)190Nn/0 | involves: C57BL/6 * DBA/2 | J:174269 | View | ||||
| Huntington's disease | Tg(Plp1-HTT*150Q)4aXjl/0 | Not Specified | J:221608 | View | ||||
| Huntington's disease | Tg(Ppp1r1b-HTT*)1Meeh/0 | C57BL/6J-Tg(Ppp1r1b-HTT*)1Meeh | J:139807 | View | ||||
| Huntington's disease | Tg(Prnp-HTT*82Q)8AGschi/0 | involves: C3H/HeJ * C57BL/6J | J:91795 | View | ||||
| Huntington's disease | Tg(Prnp-HTT*82Q)52Caro/0 | involves: C3H * C57BL/6 | J:179364 | View | ||||
| Huntington's disease | Tg(Prnp-HTT*82Q)61Gschi/0 | involves: C3H/HeJ * C57BL/6J | J:91795 | View | ||||
| Huntington's disease | Tg(Prnp-HTT*82Q,KRT14-EGFP)C63Dbo/0 | Not Specified | J:173756 | View | ||||
| Huntington's disease | Tg(Prnp-SNAP25/HTT*150Q)8Xjl/0 | involves: FVB | J:201806 | View | ||||
| Huntington's disease | Tg(UBC-GFP/HTT*84Q)22Shya/0 | involves: FVB | J:209055 | View | ||||
| Huntington's disease | Tg(YAC72)2511Hay/? | involves: FVB/N | J:55405 | View | ||||
| Huntington's disease | Tg(YAC72)2511Hay/Tg(YAC72)2511Hay | FVB/N-Tg(YAC72)2511Hay | J:105728 | View | ||||
| Huntington's disease | Tg(YAC128)53Hay/0 | FVB/N-Tg(YAC128)53Hay | J:84453, J:105723, J:111237 | View | ||||
| Huntington's disease | Tg(YAC128)55Hay/0 | FVB/N-Tg(YAC128)55Hay | J:105723 | View | ||||
| Huntington's disease | Tg(YAC128)55Hay/Tg(YAC128)55Hay | FVB/N-Tg(YAC128)55Hay | J:105723, J:105728 | View | ||||
| Huntington's disease | Tg(YAC128)#Hay/0 | FVB/N-Tg(YAC128)#Hay | J:98736 | View | ||||
| Additional Complex Models | Huntington's disease |
Drd1tm2Jcd/Drd1+ Tg(Camk2a-cre)2Gsc/0 |
involves: 129S4/SvJae * FVB/N | J:120070 | View | |||
| Huntington's disease |
Gt(ROSA)26Sortm1(HD*103Q)Xwy/? Tg(Nes-cre)1Kln/? |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL | J:99759 | View | ||||
| Huntington's disease | Gt(ROSA)26Sortm48(HTT)Arte/Gt(ROSA)26Sor+ | Not Specified | J:243843 | View | ||||
| Huntington's disease | Gt(ROSA)26Sortm49(HTT)Arte/Gt(ROSA)26Sor+ | Not Specified | J:243843 | View | ||||
| Huntington's disease | Gt(ROSA)26Sortm50(HTT)Arte/Gt(ROSA)26Sor+ | Not Specified | J:243843 | View | ||||
| Huntington's disease | Gt(ROSA)26Sortm51(HTT)Arte/Gt(ROSA)26Sor+ | Not Specified | J:243843 | View | ||||
|
No similarity to the expected human disease phenotype was found.
|
||||||||
| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | Huntington's disease |
Emx1tm1(cre)Ito/? Gt(ROSA)26Sortm1(HD*103Q)Xwy/? |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL | J:99759 | View | |||
| Huntington's disease | Hap1tm1Hay/Hap1tm1Hay | involves: 129S1/Sv * 129X1/SvJ * ICR | J:76174 | View | ||||
| Huntington's disease | Hap1tm1Xjl/Hap1tm1Xjl | involves: 129S6/SvEvTac * Black Swiss | J:84682 | View | ||||
| Huntington's disease | Htttm1Hay/Htttm1Hay | involves: C57BL/6J | J:25941 | View | ||||
| Huntington's disease | Htttm1Mem/Htttm1Mem | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 | J:27183 | View | ||||
| Huntington's disease | Htttm1Mem/Htttm7Mem | involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * CD-1 | J:44391 | View | ||||
| Huntington's disease | Htttm1Szi/Htttm1Szi | either: (involves: 129/Sv * C57BL/6J) or (involves: 129/Sv * MF1) | J:29267 | View | ||||
| Huntington's disease | Htttm2Mem/Htttm2Mem | involves: 129S1/Sv * 129X1/SvJ * CD-1 | J:99425 | View | ||||
| Huntington's disease | Htttm3Mem/Htttm3Mem | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:99425 | View | ||||
| Huntington's disease | Htttm3Mem/Htttm3Mem | involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * CD-1 | J:44391 | View | ||||
| Huntington's disease | Htttm6Mem/Htttm8Mem | involves: 129S1/Sv * 129X1/SvJ * Swiss Webster | J:72915 | View | ||||
| Huntington's disease | Htttm7Mem/Htttm7Mem | involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * CD-1 | J:44391 | View | ||||