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All mouse models of dilated cardiomyopathy with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
dilated cardiomyopathy | Cap2tm1e(EUCOMM)Wtsi/Cap2tm1e(EUCOMM)Wtsi | C57BL/6N-Cap2tm1e(EUCOMM)Wtsi | J:226742 | View | ||||
dilated cardiomyopathy | Ppp3r1tm1.1Jhon/Ppp3r1tm1.1Jhon | involves: C57BL/6 * C57BL/6NTac | J:298603 | View | ||||
dilated cardiomyopathy |
Sod2tm1Shs/Sod2tm1Shs Tg(Ckmm-cre)5Khn/0 |
involves: FVB | J:171017 | View | ||||
dilated cardiomyopathy 1A | Lmnatm1Gbon/Lmnatm1Gbon | involves: 129S2/SvPas * C57BL/6 | J:187399 | View | ||||
dilated cardiomyopathy 1A | Lmnatm1Stw/Lmnatm1Stw | involves: 129S1/Sv | J:87613, J:131905 | View | ||||
dilated cardiomyopathy 1A | Lmnatm2.1Gbon/Lmna+ | involves: 129 * C57BL/6 | J:198526 | View | ||||
dilated cardiomyopathy 1A | Lmnatm3Stw/Lmnatm3Stw | involves: 129S1/Sv * 129S4/SvJaeSor * C57BL | J:100393 | View | ||||
dilated cardiomyopathy 1C |
Ldb3tm4Chen/Ldb3tm4Chen A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ |
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * FVB/N | J:144739 | View | ||||
dilated cardiomyopathy 1C |
Ldb3tm4Chen/Ldb3tm4Chen Myl2tm1(cre)Krc/Myl2+ |
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * Black Swiss | J:144739 | View | ||||
dilated cardiomyopathy 1CC | Nexnem1Chen/Nexnem1Chen | C57BL/6J-Nexnem1Chen | J:301807 | View | ||||
dilated cardiomyopathy 1CC | Nexntm1.1Chen/Nexntm1.1Chen | Not Specified | J:290931 | View | ||||
dilated cardiomyopathy 1CC |
Nexntm1Chen/Nexntm1Chen Tg(myl7.L-cre)1118Tmhn/0 |
involves: MF1 | J:290931 | View | ||||
dilated cardiomyopathy 1CC |
Nexntm1Chen/Nexntm1Chen Tg(Tnnt2-cre)5Blh/0 |
involves: C57BL/6 * DBA/2 | J:290931 | View | ||||
dilated cardiomyopathy 1D | Tnnt2tm2.1Feah/Tnnt2+ | involves: 129S6/SvEvTac * FVB/N | J:243725 | View | ||||
dilated cardiomyopathy 1D | Tnnt2tm2Mmto/Tnnt2+ | involves: 129S/SvEv * C57BL/6 | J:137784 | View | ||||
dilated cardiomyopathy 1D | Tnnt2tm2Mmto/Tnnt2tm2Mmto | involves: 129S/SvEv * C57BL/6 | J:137784 | View | ||||
dilated cardiomyopathy 1DD | Rbm20em1Hide/Rbm20em1Hide | involves: C57BL/6J | J:297234 | View | ||||
dilated cardiomyopathy 1DD | Rbm20em3Wguo/Rbm20+ | C57BL/6-Rbm20em3Wguo | J:324088 | View | ||||
dilated cardiomyopathy 1DD | Rbm20em3Wguo/Rbm20em3Wguo | C57BL/6-Rbm20em3Wguo | J:324088 | View | ||||
dilated cardiomyopathy 1EE | Myh6tm2Ces/Myh6+ | involves: 129S/SvEv * 129X1/SvJ | J:114549 | View | ||||
dilated cardiomyopathy 1EE | Myh6tm2Ces/Myh6tm2Ces | involves: 129S/SvEv * 129X1/SvJ | J:114549 | View | ||||
dilated cardiomyopathy 1G | Ttntm1Brge/Ttn+ | B6.Cg-Ttntm1Brge | J:152736 | View | ||||
dilated cardiomyopathy 1HH |
Bag3tm1c(EUCOMM)Hmgu/Bag3tm1.1Chen Tg(Myhca-cre)1Abel/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * C57BL/6N * FVB/N | J:246352 | View | ||||
dilated cardiomyopathy 1HH |
Bag3tm1c(EUCOMM)Hmgu/Bag3tm1c(EUCOMM)Hmgu Tg(Myhca-cre)1Abel/0 |
involves: C57BL/6N * FVB/N | J:246352 | View | ||||
dilated cardiomyopathy 1I | Destm1Cap/Destm1Cap | involves: 129S7/SvEvBrd * C57BL/6 | J:35123 | View | ||||
dilated cardiomyopathy 1L | Sgcdtm1Kcam/Sgcdtm1Kcam | involves: 129S1/Sv * 129X1/SvJ | J:57107 | View | ||||
dilated cardiomyopathy 1L | Sgcdtm1Mcn/Sgcdtm1Mcn | B6.129-Sgcdtm1Mcn/J | J:234761 | View | ||||
dilated cardiomyopathy 1L | Sgcdtm1Mcn/Sgcdtm1Mcn | involves: 129S1/Sv * 129T2/SvEmsJ * 129X1/SvJ | J:76730 | View | ||||
dilated cardiomyopathy 1L | Sgcdtm1Ojml/Sgcd+ | B6.129-Sgcdtm1Ojml | J:234761 | View | ||||
dilated cardiomyopathy 1M | Csrp3tm1Crni/Csrp3tm1Crni | Not Specified | J:38213 | View | ||||
dilated cardiomyopathy 1R | Tg(Myh6-Actc1*R312H)307Iko/? | involves: C57BL/6 | J:178587 | View | ||||
dilated cardiomyopathy 1Y | Tg(Myh6-Tpm1*E54K)30Dfw/0 | involves: FVB/N | J:137813 | View | ||||
dilated cardiomyopathy 1Y | Tg(Myh6-Tpm1*E54K)67Dfw/0 | involves: FVB/N | J:137813 | View | ||||
dilated cardiomyopathy 2F | Bag5em1Asay/Bag5em1Asay | C57BL/6JJcl-Bag5em1Asay | J:327046 | View | ||||
dilated cardiomyopathy | 3425401B19Rikem1Liyu/3425401B19Rikem1Liyu | involves: C57BL/6J | J:350467 | View | ||||
dilated cardiomyopathy | b2b904.1Clo/b2b904.1Clo | C57BL/6J-b2b904.1Clo | J:175213 | View | ||||
dilated cardiomyopathy | b2b904Clo/b2b904Clo | C57BL/6J-b2b904Clo | J:175213 | View | ||||
dilated cardiomyopathy |
Cenpftm1Dbdr/Cenpftm1Dbdr Tg(Tnnt2-cre)5Blh/0 |
involves: C57BL/6 * DBA/2 * ICR | J:185133 | View | ||||
dilated cardiomyopathy | Cox7a1tm1Hutt/Cox7a1tm1Hutt | B6.129-Cox7a1tm1Hutt | J:192141 | View | ||||
dilated cardiomyopathy | Ctsltm1Cptr/Ctsltm1Cptr | involves: 129P2/OlaHsd | J:76333 | View | ||||
dilated cardiomyopathy |
Dag1tm2Kcam/Dag1tm2Kcam Myl2tm1(cre)Krc/Myl2+ |
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ | J:169951 | View | ||||
dilated cardiomyopathy |
Dicer1tm1Smr/Dicer1tm1Smr Tg(Myh6-cre)2182Mds/0 |
involves: 129S7/SvEvBrd * FVB/N | J:131962 | View | ||||
dilated cardiomyopathy | Dnm1lPy/Dnm1l+ | involves: BALB/cAnNCrl * C3H/HeH | J:161510 | View | ||||
dilated cardiomyopathy |
Erbb2tm1Cbm/Erbb2tm2Cbm Myl2tm1(cre)Krc/Myl2+ |
involves: 129P2/OlaHsd * 129S4/SvJae | J:77347 | View | ||||
dilated cardiomyopathy |
Esrrbtm1.1Nat/Esrrbtm1.1Nat Tg(Myh6-cre)2182Mds/0 |
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6N * FVB/N | J:241078 | View | ||||
dilated cardiomyopathy |
Gt(ROSA)26Sortm1(CAG-Nr2f2)Tsa/Gt(ROSA)26Sor+ A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ |
involves: 129S1/Sv * 129X1/SvJ * FVB/N | J:227012 | View | ||||
dilated cardiomyopathy |
Ilktm1Star/Ilktm1Star Tg(Ckmm-cre)1Lrsn/0 |
involves: 129S1/Sv * 129X1/SvJ * FVB/N | J:112174 | View | ||||
dilated cardiomyopathy | Lmod2Tn(pb-Act-RFP)1.1Zhu/Lmod2Tn(pb-Act-RFP)1.1Zhu | involves: FVB/N | J:233669 | View | ||||
dilated cardiomyopathy | Lrrc10tm1Sgt/Lrrc10tm1Sgt | B6.129P2-Lrrc10tm1Sgt | J:195548 | View | ||||
dilated cardiomyopathy |
Mdm4tm2Glo/Mdm4tm2.1Glo Tg(Myh6-cre)2182Mds/0 |
involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6J * FVB/N | J:137114 | View | ||||
dilated cardiomyopathy |
Med1tm2Jkr/Med1tm2Jkr A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ |
involves: 129P2/OlaHsd * FVB/N | J:243730 | View | ||||
dilated cardiomyopathy |
Med1tm2Jkr/Med1tm2Jkr Tg(Myh6-cre)2182Mds/0 |
involves: 129P2/OlaHsd * FVB/N | J:243730 | View | ||||
dilated cardiomyopathy | Mrgprdtm5Mjz/Mrgprdtm5Mjz | B6.129S1-Mrgprdtm5Mjz/Mmnc | J:269603 | View | ||||
dilated cardiomyopathy |
Mtif3tm1c(EUCOMM)Wtsi/Mtif3tm1c(EUCOMM)Wtsi Tg(Ckmm-cre)5Khn/0 |
involves: C57BL/6N | J:287609 | View | ||||
dilated cardiomyopathy | Myh6tm1Ces/Myh6+ | involves: 129S/SvEv * 129X1/SvJ | J:114549 | View | ||||
dilated cardiomyopathy | Myh6tm1Ces/Myh6tm1Ces | involves: 129S/SvEv * 129X1/SvJ | J:114549 | View | ||||
dilated cardiomyopathy |
Myocdtm1Msp/Myocdtm1Msp A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ |
involves: 129/Sv * C57BL/6J * FVB/N | J:154666 | View | ||||
dilated cardiomyopathy |
Myocdtm1Msp/Myocdtm1Msp Tg(Myh6-cre)2182Mds/0 |
involves: 129/Sv * FVB/N | J:154666 | View | ||||
dilated cardiomyopathy |
Ncoa6tm1Jkr/Ncoa6+ Tg(Myh6-cre)2182Mds/0 |
involves: 129P2/OlaHsd * FVB/N | J:269856 | View | ||||
dilated cardiomyopathy |
Ncoa6tm1Jkr/Ncoa6tm1Jkr Tg(Myh6-cre)2182Mds/0 |
involves: 129P2/OlaHsd * FVB/N | J:269856 | View | ||||
dilated cardiomyopathy | Pdcd1tm1Hon/Pdcd1tm1Hon | C.129S2(B6)-Pdcd1tm1Hon | J:66979 | View | ||||
dilated cardiomyopathy | Pdlim5tm1.1Chen/Pdlim5tm1.1Chen | involves: 129S1/Sv * 129X1/SvJ * Black Swiss | J:175042 | View | ||||
dilated cardiomyopathy |
Pdlim5tm1Chen/Pdlim5tm1Chen Tg(Tnnt2-cre)5Blh/? |
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 * DBA/2 | J:175042 | View | ||||
dilated cardiomyopathy |
Prox1tm2Gco/Prox1tm2Gco Nkx2-5tm1(cre)Rjs/Nkx2-5+ |
involves: 129S1/Sv * 129S7/SvEvBrd | J:212185 | View | ||||
dilated cardiomyopathy |
Ptger4tm1.1Matb/Ptger4tm1.1Matb Tg(Myh6-cre)2182Mds/0 |
involves: 129S6/SvEvTac * FVB/N | J:158439 | View | ||||
dilated cardiomyopathy |
Ptpn11tm1Gsf/Ptpn11tm1Gsf Tg(Ckmm-cre)5Khn/0 |
involves: 129S1/Sv * 129X1/SvJ * FVB | J:144767 | View | ||||
dilated cardiomyopathy |
Rbm24tm1.1Xixu/Rbm24tm1.1Xixu Tg(Myh6-cre)1Xya/0 |
involves: C57BL/6NTac | J:302917 | View | ||||
dilated cardiomyopathy |
Rtf1tm1c(KOMP)Wtsi/Rtf1tm1c(KOMP)Wtsi A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ |
involves: C57BL/6N * FVB/N | J:338311 | View | ||||
dilated cardiomyopathy |
Sdhaf4em1Bcgen/Sdhaf4em1Bcgen Tg(Ckmm-cre)5Khn/0 |
B6.Cg-Sdhaf4em1Bcgen Tg(Ckmm-cre)5Khn | J:345348 | View | ||||
dilated cardiomyopathy |
Srftm1Zli/Srftm1Zli A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ |
involves: 129 * C57BL/6J * FVB/N | J:135043 | View | ||||
dilated cardiomyopathy | Tbx20tm1.1Rph/Tbx20+ | involves: C57BL/6 | J:98489 | View | ||||
dilated cardiomyopathy | Tg(Myh6-Gnaq*Q209L)44Ejne/0 | involves: FVB | J:127756 | View | ||||
dilated cardiomyopathy | Tg(Myh6-Gnaq*Q209L)44Ejne/Tg(Myh6-Gnaq*Q209L)44Ejne | involves: FVB | J:127756 | View | ||||
dilated cardiomyopathy | Tg(Myh6-Gnaq*Q209L)52Ejne/? | involves: FVB | J:204274 | View | ||||
dilated cardiomyopathy | Tg(Myh6-Ppp3ca)37Eno/0 | involves: FVB | J:93176 | View | ||||
dilated cardiomyopathy | Tg(Myh6-Rab1a)highGwd/0 | involves: FVB/N | J:134581 | View | ||||
dilated cardiomyopathy | Tg(Myh6-Rab1a)lowGwd/0 | involves: FVB/N | J:134581 | View | ||||
dilated cardiomyopathy | Tg(Myh6-Rab1a)medGwd/0 | involves: FVB/N | J:134581 | View | ||||
dilated cardiomyopathy | Tg(Myh6-Rxra)41Pcn/0 | Not Specified | J:60351 | View | ||||
dilated cardiomyopathy | Tg(Myh6-Snai1)B10Jcc/0 | Not Specified | J:126850 | View | ||||
dilated cardiomyopathy | Tg(Myh6-Snai1)B10Jcc/Tg(Myh6-Snai1)B10Jcc | Not Specified | J:126850 | View | ||||
dilated cardiomyopathy | Tg(Myh6-Tmod1)65Msus/Tg(Myh6-Tmod1)65Msus | FVB/N-Tg(Myh6-Tmod1)65Msus | J:58879 | View | ||||
dilated cardiomyopathy | Tg(Myh6-Tmod1)65Msus/Tg(Myh6-Tmod1)65Msus | involves: FVB/N | J:107823 | View | ||||
dilated cardiomyopathy | Tg(Myh6-Tnf)1.6Amf/0 | involves: FVB | J:104759 | View | ||||
dilated cardiomyopathy | Tg(Myh7-Phc1)#Yota/0 | involves: C57BL/6 | J:75968 | View | ||||
dilated cardiomyopathy | Timp3tm1Rkho/Timp3tm1Rkho | B6.129-Timp3tm1Rkho | J:102205 | View | ||||
dilated cardiomyopathy | Timp3tm1Rkho/Timp3tm1Rkho | involves: 129 * C57BL/6 | J:112033 | View | ||||
dilated cardiomyopathy |
Yme1l1tm1Tlan/Yme1l1tm1Tlan Tg(Myh6-cre)2182Mds/0 |
involves: C57BL/6 * C57BL/6NCrl * FVB/N | J:229455 | View | ||||
dilated cardiomyopathy 1A |
Dot1ltm1Tche/Dot1ltm1.1Tche Tg(Myhca-cre)1Abel/0 |
Not Specified | J:168140 | View | ||||
peripartum cardiomyopathy |
Stat3tm1Vpo/Stat3tm1Vpo Tg(Myh6-cre)2182Mds/0 |
involves: 129P2/OlaHsd * FVB/N | J:141591 | View | ||||
X-linked dilated cardiomyopathy | Xlch/? | C57BL/6J-Xlch | J:136798 | View | ||||
X-linked dilated cardiomyopathy | Xlch/Xlch+ | involves: C3H/HeJ * C57BL/6J | J:136798 | View | ||||
dilated cardiomyopathy 1E | Scn5atm1(SCN5A)Rdn/Scn5atm3(SCN5A*)Rdn | involves: 129S6/SvEvTac | J:189389 | View | ||||
dilated cardiomyopathy 1E | Scn5atm3(SCN5A*)Rdn/Scn5atm3(SCN5A*)Rdn | involves: 129S6/SvEvTac | J:189389 | View | ||||
dilated cardiomyopathy 1P | Tg(Myh6-Pln*R9C)#Ces/0 | involves: FVB/N | J:82353 | View | ||||
Transgenes and Other Mutations | dilated cardiomyopathy |
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ Tg(Myh6-2A)#Know/0 |
involves: BALB/c * C57BL/6 * FVB/N | J:128060 | View | |||
dilated cardiomyopathy | Tg(CAG-Ncoa6)87Hwl/0 | involves: FVB | J:269856 | View | ||||
dilated cardiomyopathy | Tg(CAMalpha1b)7Wjk/? | Not Specified | J:134704 | View | ||||
dilated cardiomyopathy | Tg(MT2A-TGFBR2)#Rser/0 | involves: C57BL/6 * DBA | J:158480 | View | ||||
dilated cardiomyopathy | Tg(Myh6-BRUNOL4*)10Coop/0 | involves: FVB | J:99369 | View | ||||
dilated cardiomyopathy | Tg(Myh6-Camk2d_ic)LJhb/0 | either: (involves: Black Swiss) or (involves: C57BL/6) | J:130644 | View | ||||
dilated cardiomyopathy | Tg(Myh6-Camk2d_ic)MJhb/0 | either: (involves: Black Swiss) or (involves: C57BL/6) | J:130644 | View | ||||
dilated cardiomyopathy | Tg(Myh6-CASQ2)1Mord/0 | Not Specified | J:79838 | View | ||||
dilated cardiomyopathy | Tg(Myh6-cre)TG9Pjay/0 | involves: FVB/N | J:119070 | View | ||||
dilated cardiomyopathy | Tg(Myh6-CREB1*S133A)1Jml/0 | involves: CD-1 | J:133881 | View | ||||
dilated cardiomyopathy | Tg(Myh6-EGFR*)9-12Iko/0 | involves: C57BL/6 * DBA/2 | J:182337 | View | ||||
dilated cardiomyopathy | Tg(Myh6-HBEGF)#Iko/0 | involves: C57BL/6 * DBA/2 | J:93335 | View | ||||
dilated cardiomyopathy | Tg(Myh6-MYL2*D94A)1Dsc/0 | Not Specified | J:258888 | View | ||||
dilated cardiomyopathy | Tg(Myh6-NEBL*A592E)#Jato/0 | Not Specified | J:242962 | View | ||||
dilated cardiomyopathy | Tg(Myh6-NEBL*G202R)#Jato/0 | Not Specified | J:242962 | View | ||||
dilated cardiomyopathy | Tg(Myh6-Prkaca)2Eno/0 | Not Specified | J:263774 | View | ||||
dilated cardiomyopathy | Tg(Myh6-Prkaca)33Eno/0 | Not Specified | J:263774 | View | ||||
dilated cardiomyopathy | Tg(Myh6-PRKCE*A159E)344Robo/? | involves: FVB | J:198401 | View | ||||
dilated cardiomyopathy | Tg(Myh6-Rest*)474Ysai/0 | involves: C57BL/6J | J:86837 | View | ||||
dilated cardiomyopathy | Tg(Myh6-STK4)28Jusa/0 | involves: C57BL/6 | J:139414 | View | ||||
dilated cardiomyopathy | Tg(Myh6-Tnni3*)1Ammu/0 | involves: A/J * C57BL/6 | J:104770 | View | ||||
dilated cardiomyopathy |
Tg(Myh6-tTA)6Smbf/0 Tg(tetO-Spp1)5Gad/0 |
involves: C57BL/6 * CBA | J:194810 | View | ||||
dilated cardiomyopathy |
Tg(Myh6-tTA)6Smbf/0 Tg(tetORo1-lacZ)3Conk/0 |
FVB.Cg-Tg(Myh6-tTA)6Smbf Tg(tetORo1-lacZ)3Conk | J:107363 | View | ||||
dilated cardiomyopathy | Tg(Myh7-RARA/lacZ)30Mcco/0 | Not Specified | J:146424 | View | ||||
dilated cardiomyopathy 1A | Tg(Myh6-LMNA*E82K)35Lizh/0 | involves: C57BL/6J | J:167734 | View | ||||
dilated cardiomyopathy 1C | Tg(Myh6-LDB3*S196L)93Mva/0 | involves: C57BL/6J | J:243711 | View | ||||
dilated cardiomyopathy 1D | Tg(Myh6-TNNT2*R141W)#Ajm/0 | involves: C3H * C57BL/6 * ICR | J:161899 | View | ||||
dilated cardiomyopathy 1D | Tg(Myh6-TNNT2*R141W)#Lian/0 | involves: C57BL/6J | J:211769 | View | ||||
dilated cardiomyopathy 1E |
Tg(Myh6-rtTA)8585Jam/0 Tg(Myh6*/tetO-SCN5A*F1759A)#Marx/0 |
involves: C57BL/6 * CBA * FVB/NTac | J:229825 | View | ||||
dilated cardiomyopathy 1L | Tg(Myh6-Sgcd*S151A)5Mcn/0 | involves: 129T2/SvEms * C57BL/6J | J:117855 | View | ||||
dilated cardiomyopathy 1P | Tg(Myh6-Pln*)#Egk/0 | Not Specified | J:105976 | View | ||||
dilated cardiomyopathy 1R | Tg(Myh6-ACTC1*E361G)361.20Sbm/0 | Not Specified | J:242344 | View | ||||
dilated cardiomyopathy 1Y | Tg(Myh6-Tpm1*D230N)HJcf/0 | B6.FVB-Tg(Myh6-Tpm1*D230N)HJcf | J:243724 | View | ||||
Additional Complex Models | dilated cardiomyopathy |
Jundtm1Mya/Jundtm1Mya Tg(H2-K-Fosl1)1Wag/0 |
involves: 129S2/SvPas * C57BL/6 * CBA | J:95691 | View | |||
dilated cardiomyopathy 1A |
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell |
NOD.Cg-H2-Ab1b-tm1Gru Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell | J:86540 | View |
No similarity to the expected human disease phenotype was found.
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
NOT Models | dilated cardiomyopathy 1D | Tnnt2tm1Mmto/Tnnt2+ | involves: 129S/SvEv | J:141967 | View |