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All mouse models of dementia with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
frontotemporal dementia | Chmp2btm1.1Hiok/Chmp2b+ | involves: C57BL/6J | J:308471 | View | ||||
Grn-related frontotemporal lobar degeneration with Tdp43 inclusions | Grntm1.1Far/Grntm1.1Far | involves: 129S4/SvJae * C57BL/6J * FVB/N | J:218705 | View | ||||
Grn-related frontotemporal lobar degeneration with Tdp43 inclusions | Grntm1.1Hiok/Grn+ | involves: C57BL/6J | J:259943 | View | ||||
Grn-related frontotemporal lobar degeneration with Tdp43 inclusions | Grntm2.1Far/Grntm2.1Far | involves: 129S4/SvJae * C57BL/6 | J:259651 | View | ||||
frontotemporal dementia | Tardbpem1Rhbr/Tardbpem1Rhbr | C57BL/6J-Tardbpem1Rhbr | J:261673 | View | ||||
frontotemporal dementia | Tardbptm1.1Hiok/Tardbp+ | involves: C57BL/6J | J:308471 | View | ||||
frontotemporal dementia | Trem2em2Bwef/Trem2em2Bwef | involves: C57BL/6J * DBA/2J * FVB/N | J:242126 | View | ||||
frontotemporal dementia | Vcptm1.1Hiok/Vcp+ | B6(Cg)-Vcptm1.1Hiok | J:308471 | View | ||||
Grn-related frontotemporal lobar degeneration with Tdp43 inclusions | Tg(Camk2a-Tardbp)#Ckjs/Tg(Camk2a-Tardbp)#Ckjs | FVB/N-Tg(Camk2a-Tardbp)#Ckjs | J:163612 | View | ||||
Lewy body dementia |
Tg(Camk2a-SNCA*)2Mgsp/0 Del(6Snca)1Slab/Del(6Snca)1Slab |
B6JOlaHsd.Cg-Tg(Camk2a-SNCA*)2Mgsp | J:219640 | View | ||||
Transgenes and Other Mutations | frontotemporal dementia | Tg(Camk2a-MAPT)601Ymot/0 | involves: C57BL/6 * C57BL/6J | J:172762 | View | |||
frontotemporal dementia | Tg(Camk2a-MAPT*P301L)D35Jiri/0 | Not Specified | J:222897 | View | ||||
frontotemporal dementia | Tg(Camk2a-MAPT*R406W)748Atak/0 | involves: C57BL/6 * SJL | J:100958 | View | ||||
frontotemporal dementia |
Tg(Camk2a-tTA)1Mmay/0 Tg(tetO-CHMP2B*)3Fbga/0 |
involves: C57BL/6 | J:227797 | View | ||||
frontotemporal dementia | Tg(MAPT*V337M)1Gds/0 | B6J.Cg-Tg(MAPT*V337M)1Gds | J:218742 | View | ||||
frontotemporal dementia | Tg(PDGFB-MAPT*V337M)1Atak/0 | involves: C57BL/6 * SJL | J:100964 | View | ||||
frontotemporal dementia | Tg(Prnp-MAPT)7Vle/0 | involves: C57BL/6 * SJL | J:61052 | View | ||||
frontotemporal dementia | Tg(Prnp-MAPT)43Vle/0 | involves: C57BL/6 * DBA/2 | J:61052 | View | ||||
frontotemporal dementia | Tg(Prnp-MAPT*P301L)JNPL3Hlmc/? | involves: C57BL/6 * DBA/2 | J:63887 | View | ||||
frontotemporal dementia | Tg(Prnp-MAPT*P301S)50Hiw/0 | B6.Cg-Tg(Prnp-MAPT*P301S)50Hiw | J:213361 | View | ||||
frontotemporal dementia | Tg(Prnp-MAPT*R406W)21807Dwst/? | FVB/N-Tg(Prnp-MAPT*R406W)21807Dwst | J:95971 | View | ||||
frontotemporal dementia | Tg(Prnp-TARDBP*A315T)95Balo/0 | involves: C57BL/6 * CBA | J:153197 | View | ||||
frontotemporal dementia | Tg(Thy1-MAPT*)1Avil/Tg(Thy1-MAPT*)1Avil | involves: C57BL/6 * CBA | J:201700 | View | ||||
frontotemporal dementia | Tg(Thy1-MAPT*K369I)K3Gotz/0 | B6.Cg-Tg(Thy1-MAPT*K369I)K3Gotz | J:143439 | View | ||||
frontotemporal dementia | Tg(Thy1-MAPT*P301S)2541Godt/Tg(Thy1-MAPT*P301S)2541Godt | involves: C57BL/6J * CBA/Ca | J:108870 | View | ||||
frontotemporal dementia | Tg(Thy1-MAPT*V337M)1Godt/0 | involves: C57BL/6J * CBA/Ca | J:143018 | View | ||||
frontotemporal dementia | Tg(Thy1-TARDBP)4Singh/0 | involves: C57BL/6J * SJL/J | J:157550 | View | ||||
frontotemporal dementia | Tg(Thy1-TARDBP)4Singh/Tg(Thy1-TARDBP)4Singh | involves: C57BL/6J * SJL/J | J:157550 | View | ||||
frontotemporal dementia | Tg(Thy1-TARDBP)6Singh/Tg(Thy1-TARDBP)6Singh | involves: C57BL/6 * C57BL/6J * SJL | J:157550 | View | ||||
frontotemporal dementia | Tg(Tuba1-MAPT)14Vle/0 | involves: C57BL/6 * SJL | J:78400 | View | ||||
Grn-related frontotemporal lobar degeneration with Tdp43 inclusions | Tg(Prnp-TARDBP)3cPtrc/Tg(Prnp-TARDBP)3cPtrc | C57BL/6-Tg(Prnp-TARDBP)3cPtrc | J:163231 | View | ||||
Grn-related frontotemporal lobar degeneration with Tdp43 inclusions | Tg(TARDBP)#Jpj/0 | involves: C3H * C57BL/6 | J:195184 | View | ||||
Grn-related frontotemporal lobar degeneration with Tdp43 inclusions | Tg(TARDBP*A315T)#Jpj/0 | involves: C3H * C57BL/6 | J:195184 | View | ||||
Grn-related frontotemporal lobar degeneration with Tdp43 inclusions | Tg(TARDBP*G348C)#Jpj/0 | involves: C3H * C57BL/6 | J:195184 | View | ||||
Grn-related frontotemporal lobar degeneration with Tdp43 inclusions | Tg(Thy1-TARDBP*)BOddo/0 | C57BL/6-Tg(Thy1-TARDBP*)BOddo | J:180165 | View | ||||
Grn-related frontotemporal lobar degeneration with Tdp43 inclusions | Tg(Thy1-TARDBP*)BOddo/Tg(Thy1-TARDBP*)BOddo | C57BL/6-Tg(Thy1-TARDBP*)BOddo | J:223932 | View | ||||
Lewy body dementia |
Tg(Camk2a-tTA)1Mmay/0 Tg(tetO-SNCA*A53T)33Vle/0 |
involves: C3H/HeH * C57BL/6 | J:174555 | View | ||||
Lewy body dementia | Tg(PDGFB-SNCA)4Ema/0 | involves: C57BL/6 * DBA/2 | J:60638, J:137490, J:166985 | View | ||||
Lewy body dementia | Tg(PDGFB-SNCA/EGFP)78Ema/0 | involves: C57BL/6 * DBA/2 | J:238692 | View | ||||
Lewy body dementia | Tg(Thy1-SNCA*E57K)16Ema/0 | involves: C57BL/6 * DBA/2 | J:236596 | View | ||||
Pick's disease | Tg(Thy1-MAPT*L266V*G272V)13Ema/0 | involves: C57BL/6 * DBA/2 | J:229181 | View | ||||
Additional Complex Models | frontotemporal dementia | Atp2b1Tg(Thy1-CHMP2B*)1Rene/Atp2b1+ | involves: C57BL/6 * DBA/2 * FVB/N | J:237873 | View | |||
frontotemporal dementia | Atp2b1Tg(Thy1-CHMP2B*)1Rene/Atp2b1Tg(Thy1-CHMP2B*)1Rene | involves: C57BL/6 * DBA/2 * FVB/N | J:237873 | View | ||||
frontotemporal dementia |
Tg(Camk2a-tTA)1Mmay/0 Fgf14Tg(tetO-MAPT*P301L)4510Kha/Fgf14+ |
involves: 129S6/SvEvTac * FVB/N | J:207366 | View | ||||
frontotemporal dementia |
Tg(Camk2a-tTA)1Mmay/0 Fgf14Tg(tetO-MAPT*P301L)4510Kha/Fgf14+ |
involves: FVB/N | J:102973 | View | ||||
frontotemporal dementia and/or amyotrophic lateral sclerosis 7 | Atp2b1Tg(Thy1-CHMP2B*)1Rene/Atp2b1+ | involves: C57BL/6 * DBA/2 * FVB/N | J:237873 | View | ||||
frontotemporal dementia and/or amyotrophic lateral sclerosis 7 | Atp2b1Tg(Thy1-CHMP2B*)1Rene/Atp2b1Tg(Thy1-CHMP2B*)1Rene | involves: C57BL/6 * DBA/2 * FVB/N | J:237873 | View |