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All mouse models of focal segmental glomerulosclerosis with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | focal segmental glomerulosclerosis 1 | Actn4tm1Mrpk/Actn4tm1Mrpk | involves: 129 * C57BL/6 | J:83911 | View | |||
| focal segmental glomerulosclerosis 2 | Tg(NPHS2-Trpc6)F419Walz/0 | involves: C57BL/6J * CBA/J | J:165112 | View | ||||
| focal segmental glomerulosclerosis 2 | Tg(NPHS2-Trpc6*E896K)F75aWalz/0 | involves: C57BL/6J * CBA/J | J:165112 | View | ||||
| focal segmental glomerulosclerosis 2 | Tg(NPHS2-Trpc6*P111Q)F615Walz/0 | involves: C57BL/6J * CBA/J | J:165112 | View | ||||
| focal segmental glomerulosclerosis 3 | Cd2apem1Irgu/Cd2apem1Irgu | C57BL/6-Cd2apem1Irgu | J:294238 | View | ||||
| | focal segmental glomerulosclerosis |
Cmastm1.1Bwei/Cmastm1.1Bwei Tg(NPHS2-cre)295Lbh/0 |
involves: 129P2/OlaHsd * C57BL/6 * SJL | J:286022 | View | |||
| focal segmental glomerulosclerosis | Gt(ROSA)26Sortm3(tetO-Mir193)Arte/Gt(ROSA)26Sor+ | involves: 129 * BALB/c * C57BL/6 | J:197989 | View | ||||
| focal segmental glomerulosclerosis | Gt(ROSA)26Sortm3(tetO-Mir193)Arte/Gt(ROSA)26Sortm3(tetO-Mir193)Arte | involves: 129 * BALB/c * C57BL/6 | J:197989 | View | ||||
| focal segmental glomerulosclerosis | Myo9aem1Atuf/Myo9a+ | C57BL/6J-Myo9aem1Atuf | J:302901 | View | ||||
| focal segmental glomerulosclerosis |
Srgap1tm1a(KOMP)Wtsi/Srgap1tm1a(KOMP)Wtsi Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+ |
involves: 129 * C57BL/6J * C57BL/6N | J:333727 | View | ||||
| focal segmental glomerulosclerosis | Tnfaip2tm1.1Ohno/Tnfaip2tm1.1Ohno | C.Cg-Tnfaip2tm1.1Ohno | J:343202 | View | ||||
| Transgenes and Other Mutations | focal segmental glomerulosclerosis | Tg(Thy1/THY1)T6Gsv/0 | involves: C57BL/10 * CBA | J:294728, J:294621 | View | |||
| Additional Complex Models | focal segmental glomerulosclerosis |
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sortm1Sor Tg(NPHS2-rtTA2*M2)1Jbk/Tg(NPHS2-rtTA2*M2)1Jbk Tg(tetO-cre)LC1Bjd/Tg(tetO-cre)LC1Bjd |
involves: 129S4/SvJaeSor * BALB/c * C57BL/6 * FVB/N | J:285673 | View | |||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | focal segmental glomerulosclerosis 1 | Tg(CMV-Plaur*)19Lbh/0 | FVB/N-Tg(CMV-Plaur*)19Lbh | J:217443 | View | |||