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All mouse models of familial hypercholesterolemia with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | autosomal recessive hypercholesterolemia | Ldlrap1Gt(OST149604)Lex/Ldlrap1Gt(OST149604)Lex | involves: 129S5/SvEvBrd * C57BL/6 | J:102291 | View | |||
| autosomal recessive hypercholesterolemia | Ldlrap1tm1Her/Ldlrap1tm1Her | involves: 129S6/SvEvTac | J:84694 | View | ||||
| familial hypercholesterolemia |
Apobec1tm1Ddsn/Apobec1tm1Ddsn Ldlrtm1Her/Ldlrtm1Her |
involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 | J:49125 | View | ||||
| familial hypercholesterolemia | LdlrHlb301/Ldlr+ | C57BL/6J-LdlrHlb301/J | J:82961 | View | ||||
| familial hypercholesterolemia | LdlrHlb301/LdlrHlb301 | C57BL/6J-LdlrHlb301/J | J:82961 | View | ||||
| familial hypercholesterolemia | Ldlrtm1Her/Ldlrtm1Her | involves: 129S7/SvEvBrd | J:84694 | View | ||||
| familial hypercholesterolemia | Ldlrtm1Her/Ldlrtm1Her | involves: 129S7/SvEvBrd * C57BL/6 | J:102291 | View | ||||
| familial hypercholesterolemia |
Ldlrtm1Her/Ldlrtm1Her Lepob/Lepob |
B6.Cg-Lepob Ldlrtm1Her | J:72027 | View | ||||
| familial hypercholesterolemia |
Ldlrtm1Her/Ldlrtm1Her Tg(Il1rn)1Dih/Tg(Il1rn)1Dih |
involves: 129S7/SvEvBrd * C57BL/6 * CBA | J:76336 | View | ||||
| Additional Complex Models | familial hypercholesterolemia | Gt(ROSA)26Sortm1.1(Alb-PCSK9)Mby/Gt(ROSA)26Sor+ | involves: C57BL/6 * C57BL/6N | J:280156 | View | |||