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All mouse models of Down syndrome with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
Down syndrome | Dp(16Cbr1-Fam3b)1Rhr/0 | B6.129S6-Dp(16Cbr1-Fam3b)1Rhr | J:241597 | View | ||||
Down syndrome | Dp(16Cbr1-Fam3b)1Rhr/0 | involves: 129S6/SvEvTac | J:184564 | View | ||||
Down syndrome | Dp(16Cbr1-Fam3b)1Rhr/0 | involves: 129S6/SvEvTac * C3H/HeSnJ * C57BL/6Ei | J:148478 | View | ||||
Down syndrome | Tg(Dyrk1a)189N3Yah/0 | B6.129P2-Tg(Dyrk1a)189N3Yah/Yah | J:182294 | View | ||||
Down syndrome | Ts(16C-tel)1Cje/0 | B6.Cg-Ts(16C-tel)1Cje | J:294908 | View | ||||
Down syndrome | Ts(16C-tel)1Cje/0 | involves: C3H/HeSnJ * C57BL/6J * CD-1 * Rb(16.17)32Lub * STOCK Rb(11.16)2H/H | J:47907 | View | ||||
Down syndrome | Ts(16C-tel)1Cje/0 | involves: C57BL/6J * Rb(11.16)2H * Rb(16.17)32Lub | J:174270, J:241597 | View | ||||
Transgenes and Other Mutations | Down syndrome | Dp(16Hspa13-App)2Yah/0 | B6J.129P2-Dp(16Hspa13-App)2Yah | J:223518 | View | |||
Down syndrome | Dp(16Lipi-Zbtb21)1TybEmcf/0 | B6JNimr.129P2-Dp(16Lipi-Zbtb21)1TybEmcf/Nimr | J:227899 | View | ||||
Down syndrome | Dp(17Abcg1-Cbs)1Yah/0 | B6.129P2-Dp(17Abcg1-Cbs1)1Yah | J:154298 | View | ||||
Down syndrome | Rb(12.Ts171665Dn)2Cje/0 | involves: C3H/HeSnJ * C57BL/6JEiJ | J:96650 | View | ||||
Down syndrome | T(16;17)43H/0 | involves: 101 * C3H * PWD/Ph | J:208905 | View | ||||
Down syndrome | Tg(DYRK1A)36Wjs/0 | involves: C57BL/6NCrjBgi | J:111293 | View | ||||
Down syndrome | Tg(MT1A-Dyrk1a)9Xest/0 | involves: C57BL/6 * SJL | J:140647 | View | ||||
Down syndrome | Tg(MT1A-Dyrk1a)33Xest/0 | involves: C57BL/6 * SJL | J:71821 | View | ||||
Down syndrome | Tg(MT1A-Dyrk1a)#Xest/0 | involves: C57BL/6 * SJL | J:71821 | View | ||||
Down syndrome | Tg(RCAN1)M9Mapr/? | involves: C57BL/6 * CBA | J:184606 | View | ||||
Down syndrome | Ts(1716)65Dn/0 | B6EiC3Sn a/A-Ts(1716)65Dn/J | J:170195 | View | ||||
Down syndrome | Ts(1716)65Dn/0 | B6EiC3Sn.BLiA-Ts(1716)65Dn/DnJ | J:153579 | View | ||||
Down syndrome | Ts(1716)65Dn/0 | involves: BALB/c * C3H/He * C57BL/6JEiJ * DBA/2J | J:331897 | View | ||||
Down syndrome | Ts(1716)65Dn/0 | involves: C3H/HeJ * C57BL/6J * DBA/2J | J:174270 | View | ||||
Down syndrome | Ts(1716)65Dn/0 | involves: C3H/HeSnJ * C57BL/6JEi * DBA/2J | J:94569, J:96650 | View | ||||
Additional Complex Models | Down syndrome |
Dp(10Prmt2-Pdxk)2Yey/0 Dp(16Lipi-Zbtb21)1Yey/0 Dp(17Abcg1-Rrp1b)3Yey/0 |
B6.129S7-Dp(10Prmt2-Pdxk)2Yey Dp(16Lipi-Zbtb21)1Yey Dp(17Abcg1-Rrp1b)3Yey | J:161325 | View | |||
Down syndrome |
Nfatc2tm1Glm/Nfatc2tm1Glm Nfatc3tm1Glm/Nfatc3tm1Glm Nfatc4tm1Grc/Nfatc4tm1Grc |
involves: 129S2/SvPas | J:109139 | View | ||||
Down syndrome |
Nfatc2tm1Glm/Nfatc2tm1Glm Nfatc4tm1Grc/Nfatc4tm1Grc |
involves: 129S2/SvPas | J:109139 | View | ||||
Down syndrome |
Nfatc3tm1Glm/Nfatc3tm1Glm Nfatc4tm1Grc/Nfatc4tm1Grc |
involves: 129S2/SvPas | J:109139 | View | ||||
Down syndrome | Tc(HSA21)1TybEmcf/0 | involves: 129S2/SvPas * 129S8/SvEv * C57BL/6J | J:101383 | View | ||||
Down syndrome | Ts(1716)66Yah/0 | involves: C3H/HeSnJ * C57BL/6JEiJ * DBA/2J | J:331897 | View |