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All mouse models of major depressive disorder with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
major depressive disorder | Adcy3tm1Drs/Adcy3tm1Drs | involves: 129X1/SvJ * C57BL/6J | J:281839 | View | ||||
major depressive disorder | Car1tm1.1Nju/Car1tm1.1Nju | involves: C57BL/6J * C57BL/6NTac | J:336771 | View | ||||
major depressive disorder | Crtc1Gt(XK522)Byg/Crtc1Gt(XK522)Byg | B6N.129P2-Crtc1Gt(XK522)Byg | J:244400 | View | ||||
melancholic depression | Disc1Rgsc1393/Disc1Rgsc1393 | B6.Cg-Disc1Rgsc1393 | J:120634 | View | ||||
melancholic depression |
Hap1tm2Xjl/Hap1tm2Xjl Tg(CAG-cre/Esr1*)5Amc/0 |
involves: 129 * C57BL/6 * CBA | J:224698 | View | ||||
melancholic depression |
Hap1tm2Xjl/Hap1tm2Xjl Tg(Camk2a-cre)159Kln/0 |
involves: 129S6/SvEvTac * BALB/c * C57BL/6 | J:224698 | View | ||||
melancholic depression | Morc1Tg(Tyr)1Az/Morc1Tg(Tyr)1Az | involves: C57BL/6N * FVB/N | J:227356 | View | ||||
melancholic depression | Tph2tm1Mca/Tph2tm1Mca | involves: 129S6/SvEvTac * C57BL/6J | J:196373 | View | ||||
postpartum depression | Gabrdtm1Geh/Gabrdtm1Geh | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:145475 | View | ||||
Transgenes and Other Mutations | melancholic depression | Tg(Syn1-ADCY7)11004Btab/0 | B6.Cg-Tg(Syn1-ADCY7)11004Btab | J:116184 | View |
No similarity to the expected human disease phenotype was found.
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
NOT Models | melancholic depression | Pclotm1.1Mver/Pclotm1.1Mver | involves: C57BL/6 * C57BL/6J | J:225358 | View |