Excel File Text File All mouse models of cognitive disorder with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      anxiety disorder Htr1atm1Rhn/Htr1atm1Rhn involves: 129S1/Sv J:51280 View
anxiety disorder Htr1atm1Rhn/Htr1atm1Rhn involves: 129S/SvEv * 129S1/Sv J:167655 View
bipolar disorder Atp1a3Myk/Atp1a3+ B6NCr.129S1-Atp1a3Myk J:180250, J:208021 View
cognitive disorder Comttm1Kara/Comttm1Kara involves: 129S4/SvJaeSor J:49475 View
frontotemporal dementia Chmp2btm1.1Hiok/Chmp2b+ involves: C57BL/6J J:308471 View
Grn-related frontotemporal lobar degeneration with Tdp43 inclusions Grntm1.1Far/Grntm1.1Far involves: 129S4/SvJae * C57BL/6J * FVB/N J:218705 View
Grn-related frontotemporal lobar degeneration with Tdp43 inclusions Grntm1.1Hiok/Grn+ involves: C57BL/6J J:259943 View
Grn-related frontotemporal lobar degeneration with Tdp43 inclusions Grntm2.1Far/Grntm2.1Far involves: 129S4/SvJae * C57BL/6 J:259651 View
schizophrenia Akt1tm1Mbb/Akt1tm1Mbb involves: 129P2/OlaHsd * C57BL/6 J:185487 View
schizophrenia Chrna7tm1Bay/Chrna7tm1Bay B6.129S7-Chrna7tm1Bay/J J:214099 View
schizophrenia Disc1m1H/Disc1m1H B6N.C(C3H)-Disc1m1H J:229661 View
schizophrenia Disc1Rgsc1390/Disc1Rgsc1390 B6.Cg-Disc1Rgsc1390 J:120634 View
schizophrenia Disc1tm1(DISC1/DISC1FP1,DISC1FP1/DISC1,DISC1)Xzho/Disc1del 129S2/SvPasCrl-Disc1del Disc1tm1(DISC1/DISC1FP1,DISC1FP1/DISC1,DISC1)Xzho J:214737 View
schizophrenia Disc1tm1Kara/Disc1+ B6.129S6-Disc1tm1Kara J:107244 View
schizophrenia Disc1tm1Kara/Disc1tm1Kara B6.129S6-Disc1tm1Kara J:107244 View
schizophrenia Dtnbp1sdy/Dtnbp1sdy B6J.D2-Dtnbp1sdy J:197066, J:223954 View
schizophrenia Dtnbp1sdy/Dtnbp1sdy DBA/2J-Dtnbp1sdy/J J:143912 View
schizophrenia Ncstntm1.1Sud/Ncstntm1.1Sud
Olig1tm1(cre)Rth/Olig1+
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ J:234705 View
schizophrenia Tg(Camk2a-ESR1/Disc1*)2698.1Sva/0 involves: C57BL/6 * C57BL/6NTac J:127235 View
schizophrenia Tg(Disc1/EGFP)M19Sshe/0 involves: C57BL/6JCrl * CBA/CaCrl J:143557 View
      bipolar disorder Camk2atm1Sva/Camk2a+ B6.129P2-Camk2atm1Sva/J J:234969 View
bipolar disorder Clockm1Jt/Clockm1Jt involves: BALB/cJ * C57BL/6 * C57BL/6J J:166742 View
bipolar disorder Tg(Camk2a-Polg*D181A)BTkato/0 C57BL/6J-Tg(Camk2a-Polg*D181A)BTkato J:127895 View
frontotemporal dementia Tardbpem1Rhbr/Tardbpem1Rhbr C57BL/6J-Tardbpem1Rhbr J:261673 View
frontotemporal dementia Tardbptm1.1Hiok/Tardbp+ involves: C57BL/6J J:308471 View
frontotemporal dementia Trem2em2Bwef/Trem2em2Bwef involves: C57BL/6J * DBA/2J * FVB/N J:242126 View
frontotemporal dementia Vcptm1.1Hiok/Vcp+ B6(Cg)-Vcptm1.1Hiok J:308471 View
generalized anxiety disorder Zfp462Tn(pb-Act-RFP)1.090115023-HRAZhu/Zfp462+ involves: FVB/N J:262219 View
Grn-related frontotemporal lobar degeneration with Tdp43 inclusions Tg(Camk2a-Tardbp)#Ckjs/Tg(Camk2a-Tardbp)#Ckjs FVB/N-Tg(Camk2a-Tardbp)#Ckjs J:163612 View
major depressive disorder Adcy3tm1Drs/Adcy3tm1Drs involves: 129X1/SvJ * C57BL/6J J:281839 View
major depressive disorder Car1tm1.1Nju/Car1tm1.1Nju involves: C57BL/6J * C57BL/6NTac J:336771 View
major depressive disorder Crtc1Gt(XK522)Byg/Crtc1Gt(XK522)Byg B6N.129P2-Crtc1Gt(XK522)Byg J:244400 View
melancholic depression Disc1Rgsc1393/Disc1Rgsc1393 B6.Cg-Disc1Rgsc1393 J:120634 View
melancholic depression Hap1tm2Xjl/Hap1tm2Xjl
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129 * C57BL/6 * CBA J:224698 View
melancholic depression Hap1tm2Xjl/Hap1tm2Xjl
Tg(Camk2a-cre)159Kln/0
involves: 129S6/SvEvTac * BALB/c * C57BL/6 J:224698 View
melancholic depression Morc1Tg(Tyr)1Az/Morc1Tg(Tyr)1Az involves: C57BL/6N * FVB/N J:227356 View
melancholic depression Tph2tm1Mca/Tph2tm1Mca involves: 129S6/SvEvTac * C57BL/6J J:196373 View
mood disorder Tg(Camk2a-Polg*D181A)BTkato/0 C57BL/6J-Tg(Camk2a-Polg*D181A)BTkato J:127895 View
postpartum depression Gabrdtm1Geh/Gabrdtm1Geh involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:145475 View
schizoaffective disorder Gria1tm1Rsp/Gria1tm1Rsp involves: 129S1/Sv * 129X1/SvJ * C57BL/6J J:167264 View
schizoaffective disorder Gria1tm1Rsp/Gria1tm1Rsp involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J J:167264 View
schizophrenia Avpr1atm1Dgen/Avpr1atm1Dgen involves: 129P2/OlaHsd * C57BL/6 J:101679 View
schizophrenia Bace1tm1Pcw/Bace1tm1Pcw involves: 129S1/Sv * 129X1/SvJ * C57BL/6J J:133643 View
schizophrenia Chst3tm1Dgen/Chst3tm1Dgen involves: 129P2/OlaHsd * C57BL/6 J:101679 View
schizophrenia ckr/ckr involves: C3H/HeRos * C57BL/10Ros J:87399 View
schizophrenia Cplx2tm1Bros/Cplx2tm1Bros B6NCrl.Cg-Cplx2tm1Bros J:175056 View
schizophrenia Csmd1tm1Lex/Csmd1tm1Lex involves: 129S5/SvEvBrd * C57BL/6NTac J:209700 View
schizophrenia Ctsctm1Dgen/Ctsctm1Dgen involves: 129P2/OlaHsd * C57BL/6 J:101679 View
schizophrenia Grin1tm1Bhk/Grin1tm1Bhk involves: 129P2/OlaHsd * C57BL/6 * DBA/2 J:57125 View
schizophrenia Grm5tm1Rod/Grm5tm1Rod B6.129-Grm5tm1Rod J:268239 View
schizophrenia Hivep2tm1Sis/Hivep2tm1Sis either: (involves: BALB/cA * C57BL/6NCrlj * CBA/JNCrlj) or (involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj) J:263351 View
schizophrenia Hivep2tm1Sis/Hivep2tm1Sis involves: C57BL/6NCrlj * CBA/JNCrlj J:271912 View
schizophrenia Kif3btm1Noh/Kif3b+ involves: 129S4/SvJae * C57BL/6J J:286227 View
schizophrenia Lrrtm1tm1.1Jaru/Lrrtm1tm1.1Jaru involves: C57BL/6 * C57BL/6J J:174350 View
schizophrenia Map2k7tm1Pngr/Map2k7+ involves: 129P2/OlaHsd * C57BL/6J J:188339 View
schizophrenia Map6tm1Job/Map6+ involves: 129S2/SvPas * C57BL/6 J:225083 View
schizophrenia Map6tm1Job/Map6tm1Job either: 129S2/SvPas or (involves: 129S2/SvPas * BALB/c) J:79099 View
schizophrenia Map6tm1Job/Map6tm1Job involves: 129S2/SvPas * C57BL/6 J:225083 View
schizophrenia Mdktm1Tmu/Mdktm1Tmu B6.129S2-Mdktm1Tmu J:151029 View
schizophrenia Nlgn2tm1.1Gchn/Nlgn2tm1.1Gchn involves: 129S/SvEv * C57BL/6J J:272181 View
schizophrenia Nr4a2tm1Tpe/Nr4a2+ B6.129P2-Nr4a2tm1Tpe J:147544 View
schizophrenia Nrg1tm2Zhou/Nrg1+ involves: 129S4/SvJae * C57BL/6 J:81106 View
schizophrenia Nrg3tm1.1Plet/Nrg3tm1.1Plet involves: C57BL/6 J:270199 View
schizophrenia Nrxn1tm1Sud/Nrxn1tm1Sud involves: 129 * C57BL/6 J:153748 View
schizophrenia Pdgfrbtm1Msas/Pdgfrbtm1Msas
Tg(Nes-cre)1Nogu/0
B6J.Cg-Pdgfrbtm1Msas Tg(Nes-cre)1Nogu J:229179 View
schizophrenia Plcb1tm1Hssh/Plcb1tm1Hssh involves: 129/Sv * C57BL/6 J:151070 View
schizophrenia Pparaem1Tyrb/Pparaem1Tyrb C57BL/6J-Pparaem1Tyrb J:313946 View
schizophrenia Ppm1gtm1Dgen/Ppm1g+ involves: 129P2/OlaHsd * C57BL/6 J:101679 View
schizophrenia Ppp3r1tm1Stl/Ppp3r1tm1Stl
Tg(Camk2a-cre)CW2Stl/0
C57BL/6-Ppp3r1tm1Stl Tg(Camk2a-cre)CW2Stl J:73203, J:84640 View
schizophrenia Relnrl/Reln+ B6.Cg-Relnrl J:223944 View
schizophrenia Relnrl/Reln+ B6C3Fe a/a-Relnrl/J J:107996 View
schizophrenia Setd1aem1Yzhg/Setd1a+ B6.Cg-Setd1aem1Yzhg J:328716 View
schizophrenia Shank3tm4.1Gfng/Shank3tm4.1Gfng involves: 129S1/Sv * 129X1/SvJ * C57BL/6J J:230887 View
schizophrenia Slc6a1tm1Mlit/Slc6a1tm1Mlit B6.129S1-Slc6a1tm1Mlit J:204368 View
schizophrenia Slc6a3tm1Mca/Slc6a3tm1Mca involves: 129P2/OlaHsd J:31328 View
schizophrenia Snap25Bdr/Snap25+ involves: BALB/cAnNCrl J:119733 View
schizophrenia Sp4tm3(Sp4)Krc/Sp4tm3(Sp4)Krc involves: 129S1/Sv * 129X1/SvJ * Black Swiss J:163637 View
schizophrenia Srgap3tm1.1Zi/Srgap3tm1.1Zi B6.129(SJL)-Srgap3tm1.1Zi J:192388 View
schizophrenia Srrrgsc1872/Srrrgsc1872 C57BL/6JJcl-Srrrgsc1872 J:151337 View
schizophrenia Srrtm1.2Jtc/Srrtm1.2Jtc involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 J:158266 View
schizophrenia Syngap1tm1Rlh/Syngap1+ involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J J:194146 View
schizophrenia Taar1tm1Tdw/Taar1tm1Tdw involves: 129S1/Sv * C57BL/6J J:141501 View
schizophrenia Tg(Camk2a-Magi2)1Shlee/? C57BL/6J-Tg(Camk2a-Magi2)1Shlee J:218971 View
schizophrenia Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-Gnas)1593Mpke/0
B6.Cg-Tg(Camk2a-tTA)1Mmay Tg(tetO-Gnas)1593Mpke J:166114 View
schizophrenia Tg(Thy1-Tcf4)1Mjro/0 involves: C57BL/6N * FVB/N J:197081 View
schizophrenia YwhazGt(OST432062)Lex/YwhazGt(OST432062)Lex either: B6.129S5-YwhazGt(OST432062)Lex or C.129S5-YwhazGt(OST432062)Lex or (involves: 129S5/SvEvBrd * 129T2/SvEmsWehi)) J:217297 View
schizophrenia Zfp521tm1Nohk/Zfp521tm1Nohk B6J.Cg-Zfp521tm1Nohk J:214267 View
schizophrenia Zfp804aem1Yqd/Zfp804aem1Yqd involves: C57BL/6 * FVB/N J:312498 View
schizophrenia Zic2tm1Jaru/Zic2+ involves: 129S4/SvJae * C57BL/6J J:174352 View
      Lewy body dementia Tg(Camk2a-SNCA*)2Mgsp/0
Del(6Snca)1Slab/Del(6Snca)1Slab
B6JOlaHsd.Cg-Tg(Camk2a-SNCA*)2Mgsp J:219640 View
schizophrenia Del(16Dgcr2-Hira)3Aam/+ involves: 129S7/SvEvBrd * C57BL/6J J:158957 View
Transgenes and
Other Mutations
     frontotemporal dementia Tg(Camk2a-MAPT)601Ymot/0 involves: C57BL/6 * C57BL/6J J:172762 View
frontotemporal dementia Tg(Camk2a-MAPT*P301L)D35Jiri/0 Not Specified J:222897 View
frontotemporal dementia Tg(Camk2a-MAPT*R406W)748Atak/0 involves: C57BL/6 * SJL J:100958 View
frontotemporal dementia Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-CHMP2B*)3Fbga/0
involves: C57BL/6 J:227797 View
frontotemporal dementia Tg(MAPT*V337M)1Gds/0 B6J.Cg-Tg(MAPT*V337M)1Gds J:218742 View
frontotemporal dementia Tg(PDGFB-MAPT*V337M)1Atak/0 involves: C57BL/6 * SJL J:100964 View
frontotemporal dementia Tg(Prnp-MAPT)7Vle/0 involves: C57BL/6 * SJL J:61052 View
frontotemporal dementia Tg(Prnp-MAPT)43Vle/0 involves: C57BL/6 * DBA/2 J:61052 View
frontotemporal dementia Tg(Prnp-MAPT*P301L)JNPL3Hlmc/? involves: C57BL/6 * DBA/2 J:63887 View
frontotemporal dementia Tg(Prnp-MAPT*P301S)50Hiw/0 B6.Cg-Tg(Prnp-MAPT*P301S)50Hiw J:213361 View
frontotemporal dementia Tg(Prnp-MAPT*R406W)21807Dwst/? FVB/N-Tg(Prnp-MAPT*R406W)21807Dwst J:95971 View
frontotemporal dementia Tg(Prnp-TARDBP*A315T)95Balo/0 involves: C57BL/6 * CBA J:153197 View
frontotemporal dementia Tg(Thy1-MAPT*)1Avil/Tg(Thy1-MAPT*)1Avil involves: C57BL/6 * CBA J:201700 View
frontotemporal dementia Tg(Thy1-MAPT*K369I)K3Gotz/0 B6.Cg-Tg(Thy1-MAPT*K369I)K3Gotz J:143439 View
frontotemporal dementia Tg(Thy1-MAPT*P301S)2541Godt/Tg(Thy1-MAPT*P301S)2541Godt involves: C57BL/6J * CBA/Ca J:108870 View
frontotemporal dementia Tg(Thy1-MAPT*V337M)1Godt/0 involves: C57BL/6J * CBA/Ca J:143018 View
frontotemporal dementia Tg(Thy1-TARDBP)4Singh/0 involves: C57BL/6J * SJL/J J:157550 View
frontotemporal dementia Tg(Thy1-TARDBP)4Singh/Tg(Thy1-TARDBP)4Singh involves: C57BL/6J * SJL/J J:157550 View
frontotemporal dementia Tg(Thy1-TARDBP)6Singh/Tg(Thy1-TARDBP)6Singh involves: C57BL/6 * C57BL/6J * SJL J:157550 View
frontotemporal dementia Tg(Tuba1-MAPT)14Vle/0 involves: C57BL/6 * SJL J:78400 View
Grn-related frontotemporal lobar degeneration with Tdp43 inclusions Tg(Prnp-TARDBP)3cPtrc/Tg(Prnp-TARDBP)3cPtrc C57BL/6-Tg(Prnp-TARDBP)3cPtrc J:163231 View
Grn-related frontotemporal lobar degeneration with Tdp43 inclusions Tg(TARDBP)#Jpj/0 involves: C3H * C57BL/6 J:195184 View
Grn-related frontotemporal lobar degeneration with Tdp43 inclusions Tg(TARDBP*A315T)#Jpj/0 involves: C3H * C57BL/6 J:195184 View
Grn-related frontotemporal lobar degeneration with Tdp43 inclusions Tg(TARDBP*G348C)#Jpj/0 involves: C3H * C57BL/6 J:195184 View
Grn-related frontotemporal lobar degeneration with Tdp43 inclusions Tg(Thy1-TARDBP*)BOddo/0 C57BL/6-Tg(Thy1-TARDBP*)BOddo J:180165 View
Grn-related frontotemporal lobar degeneration with Tdp43 inclusions Tg(Thy1-TARDBP*)BOddo/Tg(Thy1-TARDBP*)BOddo C57BL/6-Tg(Thy1-TARDBP*)BOddo J:223932 View
Lewy body dementia Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-SNCA*A53T)33Vle/0
involves: C3H/HeH * C57BL/6 J:174555 View
Lewy body dementia Tg(PDGFB-SNCA)4Ema/0 involves: C57BL/6 * DBA/2 J:60638, J:137490, J:166985 View
Lewy body dementia Tg(PDGFB-SNCA/EGFP)78Ema/0 involves: C57BL/6 * DBA/2 J:238692 View
Lewy body dementia Tg(Thy1-SNCA*E57K)16Ema/0 involves: C57BL/6 * DBA/2 J:236596 View
melancholic depression Tg(Syn1-ADCY7)11004Btab/0 B6.Cg-Tg(Syn1-ADCY7)11004Btab J:116184 View
Pick's disease Tg(Thy1-MAPT*L266V*G272V)13Ema/0 involves: C57BL/6 * DBA/2 J:229181 View
schizophrenia Tg(Camk2a-DISC1)10Asaw/0 C57BL/6-Tg(Camk2a-DISC1)10Asaw J:124683, J:194985 View
schizophrenia Tg(Camk2a-DISC1)37Asaw/0 C57BL/6-Tg(Camk2a-DISC1)37Asaw J:124683, J:194985 View
schizophrenia Tg(Camk2a-DISC1)37Asaw/Tg(Camk2a-DISC1)37Asaw C57BL/6-Tg(Camk2a-DISC1)37Asaw J:194985 View
schizophrenia Tg(Eno2tTA)5030Nes/0
Tg(tetO-NRG1_i4)6Ajla/0
involves: C57BL/6 * C57BL/6J * SJL J:231737 View
schizophrenia Tg(GFAP-tTA)6Hyms/0
Tg(tetO-HMOX1)6Hyms/0
involves: FVB/N J:186620 View
schizophrenia 9 Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-DISC1*)1001Plet/0
involves: C57BL/6 * CBA * SJL J:146881 View
schizophrenia 9 Tg(tetO-DISC1*)70Plet/0
Tg(Camk2a-tTA)1Mmay/0
involves: C57BL/6 * CBA * SJL J:146881 View
Additional
Complex
Models
     frontotemporal dementia Atp2b1Tg(Thy1-CHMP2B*)1Rene/Atp2b1+ involves: C57BL/6 * DBA/2 * FVB/N J:237873 View
frontotemporal dementia Atp2b1Tg(Thy1-CHMP2B*)1Rene/Atp2b1Tg(Thy1-CHMP2B*)1Rene involves: C57BL/6 * DBA/2 * FVB/N J:237873 View
frontotemporal dementia Tg(Camk2a-tTA)1Mmay/0
Fgf14Tg(tetO-MAPT*P301L)4510Kha/Fgf14+
involves: 129S6/SvEvTac * FVB/N J:207366 View
frontotemporal dementia Tg(Camk2a-tTA)1Mmay/0
Fgf14Tg(tetO-MAPT*P301L)4510Kha/Fgf14+
involves: FVB/N J:102973 View
frontotemporal dementia and/or amyotrophic lateral sclerosis 7 Atp2b1Tg(Thy1-CHMP2B*)1Rene/Atp2b1+ involves: C57BL/6 * DBA/2 * FVB/N J:237873 View
frontotemporal dementia and/or amyotrophic lateral sclerosis 7 Atp2b1Tg(Thy1-CHMP2B*)1Rene/Atp2b1Tg(Thy1-CHMP2B*)1Rene involves: C57BL/6 * DBA/2 * FVB/N J:237873 View


       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      melancholic depression Pclotm1.1Mver/Pclotm1.1Mver involves: C57BL/6 * C57BL/6J J:225358 View
schizophrenia Csmd1tm1Lex/Csmd1tm1Lex B6;129S5-Csmd1tm1Lex/Mmucd J:194991 View
schizophrenia Rtn4rrgsc1836/Rtn4rrgsc1836 C57BL/6JJcl-Rtn4rrgsc1836 J:176996 View
schizophrenia Rtn4rtm1Gogo/Rtn4rtm1Gogo involves: 129 * C57BL/6J J:130368 View