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All mouse models of intrahepatic cholestasis with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
intrahepatic cholestasis | Abcb4tm1Bor/Abcb4tm1Bor | involves: 129P2/OlaHsd * FVB/N | J:175015 | View | ||||
intrahepatic cholestasis |
Abcb4tm1Bor/Abcb4tm1Bor Portm1Wolf/Portm1Wolf Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129P2/OlaHsd * C57BL/6 * DBA * FVB/N | J:215915 | View | ||||
intrahepatic cholestasis |
Atp8b1tm1Nbf/Atp8b1tm1Nbf Portm1Wolf/Portm1Wolf Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA | J:215915 | View | ||||
progressive familial intrahepatic cholestasis 4 |
Tjp1tm1.1Whun/Tjp1tm1.1Whun Tjp2tm2Whun/Tjp2tm2Whun Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6N * C57BL/6NTac * DBA/2 | J:306936 | View |
No similarity to the expected human disease phenotype was found.
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
NOT Models | intrahepatic cholestasis | Atp8b1tm1Nbf/Atp8b1tm1Nbf | involves: 129S1/SvImJ * 129S4/SvJae | J:89817 | View |