Excel File Text File All mouse models of reproductive organ cancer with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      ovarian cancer Amhr2tm3(cre)Bhr/Amhr2+
Ctnnb1tm1Mmt/Ctnnb1+
involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 J:186144 View
ovarian cancer Amhr2tm3(cre)Bhr/Amhr2+
Ctnnb1tm1Mmt/Ctnnb1+
Ptentm1Hwu/Ptentm1Hwu
involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 J:186144 View
ovarian cancer Ctnnb1tm1Mmt/Ctnnb1+
Krastm4Tyj/Kras+
Amhr2tm3(cre)Bhr/Amhr2+
involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 J:186144 View
ovarian cancer Ctnnb1tm1Mmt/Ctnnb1+
Krastm4Tyj/Kras+
Tg(CYP19A1-cre)1Jri/0
involves: 129S4/SvJae * 129X1/SvJ * C57BL/6 J:186144 View
ovarian cancer Ctnnb1tm1Mmt/Ctnnb1+
Ptentm1Hwu/Ptentm1Hwu
Tg(CYP19A1-cre)1Jri/0
involves: 129S4/SvJae * 129X1/SvJ * C57BL/6 J:186144 View
ovarian cancer Ctnnb1tm1Mmt/Ctnnb1+
Tg(CYP19A1-cre)1Jri/0
involves: 129X1/SvJ * C57BL/6 J:186144 View
prostate cancer Acp3tm1Pivi/Acp3tm1Pivi B6.Cg-Acp3tm1Pivi J:207558 View
prostate cancer Apctm1Tno/Apctm1Tno
Tg(Pbsn-cre)4Prb/0
involves: 129S4/SvJae * C57BL/6 * C57BL/6J * DBA/2 J:120308 View
prostate cancer Artm1Verh/Y
Ptentm1Hwu/Ptentm1Hwu
Tg(Pbsn-cre)4Prb/0
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * DBA/2 J:172730 View
prostate cancer Braftm1Mmcm/Braftm1Mmcm
Nkx3-1tm4(cre/ERT2)Mms/Nkx3-1+
Ptentm1Hwu/Pten+
involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac * C57BL/6 J:191327 View
prostate cancer Gt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki/Gt(ROSA)26Sor+
Ptentm1Mro/Pten+
Tg(Pbsn-cre)4Prb/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N J:184533 View
prostate cancer Gt(ROSA)26Sortm1(JAG1)Xin/Gt(ROSA)26Sor+
Ptentm1Hwu/Ptentm1Hwu
Tg(Pbsn-cre)20Fwan/?
involves: 129S4/SvJae * C57BL/6 * FVB/NCrl J:238768 View
prostate cancer Gt(ROSA)26Sortm1(SPOP*F133V)Mrbn/Gt(ROSA)26Sor+
Ptentm2.1Ppp/Pten+
Tg(Pbsn-cre)4Prb/0
involves: 129S1/Sv * C57BL/6 * DBA/2 J:239660 View
prostate cancer Gt(ROSA)26Sortm1(SPOP*F133V)Mrbn/Gt(ROSA)26Sor+
Ptentm2.1Ppp/Ptentm2.1Ppp
Tg(Pbsn-cre)4Prb/0
involves: 129S1/Sv * C57BL/6 * DBA/2 J:239660 View
prostate cancer Igs2tm1(CAG-Met)Zsu/Igs2+
Ptentm1Hwu/Ptentm1Hwu
Tg(Pbsn-cre)4Prb/0
involves: 129 * C57BL/6 * DBA/2 * FVB/N J:268934 View
prostate cancer Krastm4Tyj/Kras+
Ptentm1Hwu/Pten+
Tg(Pbsn-cre)4Prb/0
involves: 129S4/SvJae * C57BL/6 * DBA/2 J:184935 View
prostate cancer Krastm4Tyj/Kras+
Ptentm1Hwu/Ptentm1Hwu
Tg(Pbsn-cre)4Prb/0
involves: 129S4/SvJae * C57BL/6 * DBA/2 J:184935 View
prostate cancer Nkx3-1tm1Mms/Nkx3-1+
Ptentm1Rps/Pten+
involves: 129S1/Sv * 129S1/SvImJ * C57BL/6J J:75085 View
prostate cancer Nkx3-1tm1Mms/Nkx3-1tm1Mms
Ptentm1Rps/Pten+
involves: 129S1/Sv * 129S1/SvImJ * C57BL/6J J:75085 View
prostate cancer Ptentm1Hwu/Pten+
Tg(ARR2/Pbsn-FGF8)3Prb/0
Tg(Pbsn-cre)4Prb/0
involves: 129S4/SvJae * BALB/c * C57BL/6 * DBA/2 J:106650 View
prostate cancer Ptentm1Hwu/Ptentm1Hwu
Tg(CAG-MYC,-GFP*)#Rugg/0
Tg(Pbsn-cre)4Prb/0
involves: 129S4/SvJae * C57BL/6 * C57BL/6J * DBA/2 J:261540 View
prostate cancer Ptentm1Hwu/Ptentm1Hwu
Tg(Pbsn-cre)4Prb/0
involves: 129S4/SvJae * BALB/c * C57BL/6 * DBA/2 J:93902 View
prostate cancer Ptentm1Hwu/Ptentm1Hwu
Tg(Pbsn-cre)4Prb/0
involves: 129S4/SvJae * C57BL/6 * DBA/2 J:172730, J:184935 View
prostate cancer Ptentm1Hwu/Ptentm1Hwu
Tg(Pbsn-cre)20Fwan/?
involves: 129S4/SvJae * C57BL/6 * FVB/NCrl J:238768 View
prostate cancer Ptentm1Ppp/Pten+
Tg(Pbsn-TAg)15Tvd/0
involves: 129S1/Sv * C57BL/6 * DBA/2 J:103408 View
prostate cancer Ptentm1Rdp/Ptentm1Rdp
Terttm3Rdp/Terttm3Rdp
Trp53tm1Brn/Trp53tm1Brn
Tg(Pbsn-cre)4Prb/0
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2 J:186105 View
prostate cancer Ptentm2.1Ppp/Pten+
Spry1tm1Jdli/Spry1tm1.1Jdli
Spry2tm1Mrt/Spry2tm1.1Mrt
Tg(Osr1-cre)4Mrt/0
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N J:192348 View
prostate cancer Ptentm2Mak/Ptentm2Mak
Tg(KLK3-cre)13Saa/0
involves: 129P2/OlaHsd * C57BL/6 J:214242 View
      endometrial cancer Errfi1tm1Jwj/Errfi1tm1Jwj
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129X1/SvJ J:150007 View
endometrial cancer Errfi1tm1Jwj/Errfi1tm1Jwj
Pgrtm2(cre)Lyd/Pgr+
Ptentm1Hwu/Ptentm1Hwu
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ J:162027 View
endometrial cancer Pgrtm2(cre)Lyd/Pgr+
Ptentm1Hwu/Ptentm1Hwu
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 J:139053 View
endometrial cancer Pgrtm2(cre)Lyd/Pgr+
Ptentm1Hwu/Ptentm1Hwu
Trp53tm1Brn/Trp53tm1Brn
involves: 129 * C57BL/6 J:139053 View
endometrial cancer Stk11tm1.1Rdp/Stk11tm1.1Rdp
Tg(Sprr2f-cre)1Dcas/0
involves: 129S6/SvEvTac * FVB/N J:158190 View
endometrial cancer Trp53tm1Brn/Trp53tm1Brn
Tg(Cdh16-cre)91Igr/0
involves: 129P2/OlaHsd * C57BL/6J * FVB/N * ICR J:214850 View
granulosa cell tumor Amhr2tm3(cre)Bhr/Amhr2+
Ctnnb1tm1Mmt/Ctnnb1+
involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 J:186144 View
granulosa cell tumor Amhr2tm3(cre)Bhr/Amhr2+
Ctnnb1tm1Mmt/Ctnnb1+
Ptentm1Hwu/Ptentm1Hwu
involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ J:142150 View
granulosa cell tumor Amhr2tm3(cre)Bhr/Amhr2+
Ctnnb1tm1Mmt/Ctnnb1+
Ptentm1Hwu/Ptentm1Hwu
involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 J:186144 View
granulosa cell tumor Ctnnb1tm1Mmt/Ctnnb1+
Krastm4Tyj/Kras+
Amhr2tm3(cre)Bhr/Amhr2+
involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 J:186144 View
granulosa cell tumor Ctnnb1tm1Mmt/Ctnnb1+
Krastm4Tyj/Kras+
Tg(CYP19A1-cre)1Jri/0
involves: 129S4/SvJae * 129X1/SvJ * C57BL/6 J:186144 View
granulosa cell tumor Ctnnb1tm1Mmt/Ctnnb1+
Ptentm1Hwu/Ptentm1Hwu
Tg(CYP19A1-cre)1Jri/0
involves: 129S4/SvJae * 129X1/SvJ * C57BL/6 J:186144 View
ovarian cancer Apctm1Rsmi/Apctm1Rsmi
Pgrtm2(cre)Lyd/Pgr+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J J:210095 View
ovarian cancer Apctm1Tno/Apctm1Tno
Ptentm2Mak/Ptentm2Mak
involves: 129P2/OlaHsd * 129S4/SvJae J:120955 View
prostate cancer Ctnnb1tm1Mmt/Ctnnb1+
Igs2tm1(CAG-Met)Zsu/Igs2+
Tg(Pbsn-cre)4Prb/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 * FVB/N J:284956 View
prostate cancer Ctnnb1tm1Mmt/Ctnnb1+
Tg(Pbsn-cre)4Prb/0
involves: 129X1/SvJ * C57BL/6 * DBA/2 J:143034 View
prostate cancer Krastm1Bbd/Kras+
Tg(Pbsn-cre)4Prb/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 J:143034 View
prostate cancer Krastm4Tyj/Kras+
Scribtm1.1Phum/Scribtm1.1Phum
Tg(Pbsn-cre)20Fwan/0
involves: 129S4/SvJae * FVB/NCrl J:178461 View
prostate cancer Msmbtm1Xuan/Msmbtm1Xuan either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * CD-1) J:96884 View
prostate cancer Nkx3-1tm1Hha/Nkx3-1+ involves: 129S4/SvJae * C57BL/6 J:63764 View
prostate cancer Nkx3-1tm1Hha/Nkx3-1tm1Hha involves: 129S4/SvJae * C57BL/6 J:63764 View
prostate cancer Nkx3-1tm1Mms/Nkx3-1+ either: (involves: 129S1/Sv * 129S1/SvImJ) or (involves: 129S1/Sv * 129S1/SvImJ * C57BL/6J) J:54465 View
prostate cancer Nkx3-1tm1Mms/Nkx3-1tm1Mms either: (involves: 129S1/Sv * 129S1/SvImJ) or (involves: 129S1/Sv * 129S1/SvImJ * C57BL/6J) J:54465 View
prostate cancer Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm
Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0
involves: 129S6/SvEvTac * C57BL/6 * DBA/2 J:204736 View
uterine cancer Tg(H2-K-Hmga1)#Lmsr/0 involves: C57BL/6 * SJL J:121308 View
      ovarian cancer Arid1atm1.1Mag/Arid1atm1.1Mag
Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/Gt(ROSA)26Sor+
involves: 129S6/SvEvTac * CD-1 J:219794 View
ovarian cancer Brca1tm1Brn/Brca1tm1Brn
Tg(Krt18-EGFP,-TAg121)36Ysng/0
Trp53tm1Brn/Trp53tm1Brn
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N J:189304 View
ovarian cancer Brca1tm1Brn/Brca1tm1Brn
Tg(Krt18-EGFP,-TAg121)36Ysng/0
Trp53tm1Brn/Trp53tm2Tyj
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N J:189304 View
ovarian cancer Brca2tm1Brn/Brca2tm1Brn
Tg(Krt18-EGFP,-TAg121)36Ysng/0
Trp53tm1Brn/Trp53tm2Tyj
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N J:189304 View
ovarian cancer Dicer1tm1Tara/Dicer1tm1Tara
Ptentm1Hwu/Ptentm1Hwu
Amhr2tm3(cre)Bhr/Amhr2+
involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd J:182161 View
ovarian cancer Dicer1tm1Tara/Dicer1tm1Tara
Ptentm1Hwu/Ptentm1Hwu
Trp53tm2Tyj/Trp53+
Amhr2tm3(cre)Bhr/Amhr2+
involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd J:222579 View
ovarian cancer Krastm4Tyj/Kras+
Ptentm1Hwu/Ptentm1Hwu
involves: 129S4/SvJae J:161953 View
ovarian cancer Krastm4Tyj/Kras+
Ptentm1Hwu/Ptentm1Hwu
involves: 129S4/SvJae * C57BL/6J J:96296 View
ovarian cancer Ptentm1Hwu/Ptentm1Hwu
Trp53tm2Tyj/Trp53+
Amhr2tm3(cre)Bhr/Amhr2+
involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd J:222579 View
prostate cancer Artm1(AR)Dmr/Y
Tg(TRAMP)8247Ng/0
involves: 129S1/Sv * C57BL/6 J:108849 View
prostate cancer Artm2(AR)Dmr/Y
Tg(TRAMP)8247Ng/0
involves: 129S1/Sv * C57BL/6 J:108849 View
prostate cancer Artm3(AR)Dmr/Y
Tg(TRAMP)8247Ng/0
involves: 129S1/Sv * C57BL/6 J:108849 View
prostate cancer Brca2tm1Brn/Brca2tm1Brn
Trp53tm1Brn/Trp53tm1Brn
Tg(Pbsn-cre)4Prb/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 J:161511 View
prostate cancer Cdkn2atm1Rdp/Cdkn2atm1Rdp
Tg(tetO-BRAF*V600E)29Lc/0
Tg(Tyr-rtTA)37Lc/0
involves: 129/Sv * C57BL/6J * SJL J:144358 View
Transgenes and
Other Mutations
     ovarian cancer Tg(Amhr2-SV40TAg)1Dcco/0 (C57BL/6 x C3H)F1 J:82550 View
ovarian cancer Tg(CAG-lacZ,-SV40)#Bcv/0 involves: FVB/N J:158388 View
prostate adenocarcinoma Tg(Pbsn-Tag)12T10Rjm/0 involves: CD-1 J:68483 View
prostate cancer Tg(ARR2/Pbsn-MYC)7Key/? involves: FVB/N J:85480 View
prostate cancer Tg(C3-1-TAg)cJeg/0 involves: FVB/N J:52786 View
prostate cancer Tg(CAG-SAC/EGFP)35Rang/0
Tg(TRAMP)8247Ng/0
involves: C3H * C57BL/6 J:125633 View
prostate cancer Tg(Ggamma-T)15Cps/0 involves: C57BL/6J * CBA/J J:38778 View
prostate cancer Tg(Ggamma-T)15Cps/Tg(Ggamma-T)15Cps involves: C57BL/6J * CBA/J J:38778 View
prostate cancer Tg(H-2K1-Lrp5/Fkbp1a,-luc*)#Dmps/0
Tg(Pbsn-Fgfr1/Fkbp1a)#aDmsp/0
involves: FVB/N J:206727 View
prostate cancer Tg(Msmb-TAg)183-2Xuan/0 involves: C57BL/6 * CBA J:80313 View
prostate cancer Tg(Msmb-TAg)186-3Xuan/0 involves: C57BL/6 * CBA J:80313 View
prostate cancer Tg(Pbsn-Ar*E231G)7353Ng/0 involves: FVB/N J:96117 View
prostate cancer Tg(Pbsn-ERG*)1Vv/0 involves: 129S1/SvImJ * C57BL/6J * CBA J:222916 View
prostate cancer Tg(Pbsn-Fgfr1/Fkbp1a)#aDmsp/0 FVB-Tg(Pbsn-Fgfr1/Fkbp1a)#aDmsp J:130340 View
prostate cancer Tg(Pbsn-IGF1*)5305Ng/0
Tg(TRAMP)8247Ng/0
involves: C57BL/6 * FVB/N J:144539 View
prostate cancer Tg(Pbsn-MYC)6Key/? involves: FVB J:85480 View
prostate cancer Tg(Pbsn-MYC)#Tt/? involves: C57BL/6J J:205395 View
prostate cancer Tg(Pbsn-Tag)12T7fRjm/0 involves: CD-1 J:48623 View
prostate cancer Tg(Pbsn-TAg)15Tvd/0 involves: C57BL/6 * DBA/2 J:103408 View
prostate cancer Tg(TRAMP)8247Ng/0 involves: C57BL/6 J:65303 View
Additional
Complex
Models
     juvenile type testicular granulosa cell tumor Amhr2tm3(cre)Bhr/Amhr2+
Ctnnb1tm1Mmt/Ctnnb1+
Ptentm1Hwu/Ptentm1Hwu
involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 J:186144 View
juvenile type testicular granulosa cell tumor Ctnnb1tm1Mmt/Ctnnb1+
Krastm4Tyj/Kras+
Amhr2tm3(cre)Bhr/Amhr2+
involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 J:186144 View
ovarian cancer Amhr2tm3(cre)Bhr/Amhr2+
Smad1tm2Rob/Smad1tm2.1Rob
Smad5tm1Huy/Smad5tm1Huy
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J J:157310 View
ovarian cancer Amhr2tm3(cre)Bhr/Amhr2+
Smad1tm2Rob/Smad1tm2Rob
Smad5tm1Huy/Smad5tm1Huy
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J J:157310 View
ovarian cancer Amhr2tm3(cre)Bhr/Amhr2+
Smad1tm2Rob/Smad1tm2Rob
Smad5tm1Huy/Smad5tm1Zuk
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J J:157310 View
ovarian cancer Cdkn1btm1Ako/Cdkn1b+
KitW-v/KitW-v
involves: 129S1/Sv * C57BL/6J J:236161 View
ovarian cancer Cdkn1btm1Ako/Cdkn1btm1Ako
KitW-v/KitW-v
involves: 129S1/Sv * C57BL/6J J:236161 View
ovarian cancer Foxo1tm1Rdp/Foxo1tm1.1Rdp
Foxo3tm1Rdp/Foxo3tm1.1Rdp
Amhr2tm3(cre)Bhr/Amhr2+
involves: 129S6/SvEvTac * 129S7/SvEvBrd J:232961 View
ovarian cancer Foxo1tm1Rdp/Foxo1tm1.1Rdp
Foxo3tm1Rdp/Foxo3tm1.1Rdp
Tg(CYP19A1-cre)1Jri/0
involves: 129S6/SvEvTac J:232961 View
ovarian cancer KitW-v/KitW-v
Trp53tm1Brn/Trp53tm1Brn
involves: 129P2/OlaHsd * C57BL/6J * FVB/N J:236161 View
ovarian cancer Rb1tm2Brn/Rb1tm2Brn
Trp53tm1Brn/Trp53tm1Brn
involves: 129P2/OlaHsd J:84345 View
ovarian cancer Tg(Krt18-EGFP,-TAg121)36Ysng/0
Trp53tm1Brn/Trp53tm1Brn
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N J:189304 View
ovarian cancer Tg(Krt18-EGFP,-TAg121)36Ysng/0
Trp53tm1Brn/Trp53tm2Tyj
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N J:189304 View
prostate adenocarcinoma Gt(ROSA)26Sortm1(CAG-AR)Zsu/Gt(ROSA)26Sor+
Tg(Osr1-cre)4Mrt/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N J:234601 View
prostate adenocarcinoma Gt(ROSA)26Sortm1(CAG-AR)Zsu/Gt(ROSA)26Sortm1(CAG-AR)Zsu
Tg(Osr1-cre)4Mrt/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N J:234601 View
prostate cancer Col1a1tm1(tetO-YAP1*)Fcam/Col1a1+
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+
Tg(Pbsn-cre)4Prb/0
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * DBA/2 J:222916 View
prostate neuroendocrine neoplasm Gt(ROSA)26Sortm1(CAG-MYCN,-luc)Jhsc/Gt(ROSA)26Sor+
Ptentm2.1Ppp/Ptentm2.1Ppp
Rb1tm2Brn/Rb1+
Tg(Pbsn-cre)4Prb/0
involves: 129 * 129S1/Sv * 129S6/SvEvTac * C57BL/6 * DBA/2 J:307910 View
prostate neuroendocrine neoplasm Gt(ROSA)26Sortm1(CAG-MYCN,-luc)Jhsc/Gt(ROSA)26Sor+
Ptentm2.1Ppp/Ptentm2.1Ppp
Rb1tm2Brn/Rb1tm2Brn
Tg(Pbsn-cre)4Prb/0
involves: 129 * 129S1/Sv * 129S6/SvEvTac * C57BL/6 * DBA/2 J:307910 View
testicular granulosa cell tumor Amhr2tm3(cre)Bhr/Amhr2+
Ctnnb1tm1Mmt/Ctnnb1+
Ptentm1Hwu/Ptentm1Hwu
involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ J:149060 View


       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      ovarian cancer Tg(Amhr2-Pik3ca*,-GFP)#Lzh/0 involves: C3H * C57BL/6 J:144834 View