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All mouse models of degeneration of macula and posterior pole with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | age related macular degeneration 4 | Cfhtm1Mbo/Cfhtm1Mbo | B6.129-Cfhtm1Mbo | J:203471 | View | |||
| age related macular degeneration 12 | Cx3cr1tm1Zm/Cx3cr1tm1Zm | C.129-Cx3cr1tm1Zm | J:127548 | View | ||||
| age related macular degeneration 12 | Cx3cr1tm1Zm/Cx3cr1tm1Zm | involves: 129 * C57BL/6 | J:127548 | View | ||||
| Doyne honeycomb retinal dystrophy | Efemp1tm1Eap/Efemp1+ | involves: 129S6/SvEvTac * C57BL/6 * FVB/N | J:129901 | View | ||||
| Doyne honeycomb retinal dystrophy | Efemp1tm1Eap/Efemp1tm1Eap | involves: 129S6/SvEvTac * C57BL/6 * FVB/N | J:129901 | View | ||||
| Doyne honeycomb retinal dystrophy | Efemp1tm1Lmar/Efemp1+ | involves: 129X1/SvJ * BALB/c | J:129902 | View | ||||
| Doyne honeycomb retinal dystrophy | Efemp1tm1Lmar/Efemp1tm1Lmar | involves: 129X1/SvJ * BALB/c | J:129902 | View | ||||
| | age related macular degeneration | Ccl2tm1Rol/Ccl2tm1Rol | B6.129S4-Ccl2tm1Rol | J:147328 | View | |||
| age related macular degeneration |
Ccl2tm1Rol/Ccl2tm1Rol Cx3cr1tm1Litt/Cx3cr1tm1Litt |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J | J:200877 | View | ||||
| age related macular degeneration |
Ccl2tm1Rol/Ccl2tm1Rol Cx3cr1tm1Zm/Cx3cr1tm1Zm |
involves: 129 * 129S4/SvJae | J:126935 | View | ||||
| age related macular degeneration | Ccr2tm1Mae/Ccr2tm1Mae | B6.129P2-Ccr2tm1Mae | J:147328 | View | ||||
| age related macular degeneration | Cd46tm1Atk/Cd46tm1Atk | B6.129-Cd46tm1Atk | J:234294 | View | ||||
| age related macular degeneration | Ppargc1atm1Brsp/Ppargc1a+ | involves: 129S4/SvJae * C57BL/6 | J:264271 | View | ||||
| age related macular degeneration 1 |
Cryba1tm1.1Dbsa/Cryba1tm1.1Dbsa Tg(BEST1-cre)1Jdun/0 |
involves: 129S6/SvEvTac * C57BL/6 | J:215531 | View | ||||
| age related macular degeneration 1 | Vldlrtm1Her/Vldlrtm1Her | B6;129S7-Vldlrtm1Her/J | J:132497 | View | ||||
| Stargardt disease | Abca4tm1.1Rsmy/Abca4tm1.1Rsmy | involves: C57BL/6 | J:255529 | View | ||||
| Stargardt disease | Abca4tm1Ght/Abca4tm1Ght | involves: 129S4/SvJae | J:141801 | View | ||||
| Stargardt disease | Abca4tm1Ght/Abca4tm1Ght | involves: 129S4/SvJae * BALB/c | J:141801 | View | ||||
| Stargardt disease | Abca4tm1Ght/Abca4tm1Ght | involves: 129S4/SvJae * C57BL/6 | J:56317 | View | ||||
| Stargardt disease |
Abca4tm1Kpal/Abca4tm1Kpal Rdh8tm1Kpal/Rdh8tm1Kpal |
involves: 129 | J:213619 | View | ||||
| Stargardt disease | Elovl4tm1Rayy/Elovl4+ | involves: 129 * C57BL/6J | J:114752 | View | ||||
| Stargardt disease | Elovl4tm1Wked/Elovl4+ | involves: 129S/SvEv * 129S1/Sv | J:121481 | View | ||||
| | age related macular degeneration 1 | Apoetm3(APOE*4)Mae/Apoetm3(APOE*4)Mae | involves: 129P2/OlaHsd * C57BL/6 | J:101147 | View | |||
| age related macular degeneration 2 |
Abca4tm1Ght/Abca4tm1Ght Rdh8tm1Kpal/Rdh8tm1Kpal |
involves: 129 * 129S4/SvJae | J:154536 | View | ||||
| Transgenes and Other Mutations | age related macular degeneration 1 | Tg(APOB)1102Sgy/? | B6.Cg-Tg(APOB)1102Sgy | J:151253 | View | |||
| Stargardt disease | Tg(RBP3-ELOVL4*)1Kzh/0 | C57BL/6-Tg(RBP3-ELOVL4*)1Kzh | J:97173 | View | ||||
| Stargardt disease | Tg(RBP3-ELOVL4*)2Kzh/0 | C57BL/6-Tg(RBP3-ELOVL4*)2Kzh | J:97173 | View | ||||
| Stargardt disease | Tg(RBP3-ELOVL4*)3Kzh/0 | C57BL/6-Tg(RBP3-ELOVL4*)3Kzh | J:97173 | View | ||||
| Additional Complex Models | age related macular degeneration |
Abca4tm1Kpal/Abca4tm1Kpal Rdh8tm1Kpal/Rdh8tm1Kpal |
involves: 129 | J:213619 | View | |||
| age related macular degeneration 1 |
Cptm1Hrs/Cptm1Hrs Hephsla/Y |
involves: 129X1/SvJ * C57BL/6 | J:136925 | View | ||||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | Stargardt disease | Elovl4tm1Sie/Elovl4+ | involves: 129P2/OlaHsd * C57BL/6 | J:112264 | View | |||
| Stargardt disease | Elovl4tm1Sie/Elovl4tm1Sie | involves: 129P2/OlaHsd * C57BL/6 | J:112264 | View | ||||