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All mouse models of hyperostosis with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
hereditary multiple exostoses |
Ext1tm1.1Vcs/Ext1tm1.1Vcs Tg(Col2a1-cre/ERT)KA3Smac/0 |
involves: 129S1/Sv * 129X1/SvJ * FVB/N | J:242977 | View | ||||
hereditary multiple exostoses |
Ext1tm1.1Vcs/Ext1tm1.1Vcs Tg(Col2a1-rtTA,tetO-cre)22Pjro/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL | J:157599 | View | ||||
hereditary multiple exostoses |
Ext1tm1Vcs/Ext1tm1Vcs Tg(Col2a1-rtTA,tetO-cre)22Pjro/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:157599 | View | ||||
hereditary multiple exostoses |
Ext1tm1Yama/Ext1tm1Yama Acantm1(cre/ERT2)Crm/Acan+ |
involves: 129S5/SvEvBrd * 129S6/SvEvTac * C57BL/6NCrl | J:242977 | View | ||||
hereditary multiple exostoses |
Ext1tm1Yama/Ext1tm1Yama Tg(Col2a1-cre/ERT)KA3Smac/0 |
involves: 129S5/SvEvBrd * FVB/N | J:161395 | View | ||||
Paget's disease of bone | Sqstm1tm1.1Sral/Sqstm1+ | involves: 129/Sv * 129P2/OlaHsd * C57BL/6 | J:173755 | View | ||||
Paget's disease of bone | Sqstm1tm1.1Sral/Sqstm1tm1.1Sral | involves: 129/Sv * 129P2/OlaHsd * C57BL/6 | J:173755 | View | ||||
Paget's disease of bone | Sqstm1tm1Keta/Sqstm1tm1Keta | involves: 129 * C57BL/6N | J:264183 | View | ||||
Paget's disease of bone | Tnfrsf11atm1.1Sral/Tnfrsf11a+ | B6.129P2(Cg)-Tnfrsf11atm1.1Sral | J:312215 | View | ||||
sclerosteosis 1 | Sosttm1Paz/Sosttm1Paz | involves: 129/Sv * Black Swiss | J:213541 | View | ||||
sclerosteosis 2 | Lrp4mdig-3J/Lrp4mdig-3J | B6.Cg-Lrp4mdig-3J/GrsrJ | J:224655 | View | ||||
sclerosteosis 2 | Lrp4tm1.1Pg/Lrp4tm1.1Pg | involves: C57BL/6N | J:277372 | View | ||||
hereditary multiple exostoses | Ext2tm1Werb/Ext2+ | involves: C57BL/6 | J:103125 | View | ||||
Paget's disease of bone | Inpp5dtm1Rkh/Inpp5dtm1Rkh | involves: 129S1/Sv * 129X1/SvJ | J:78771 | View | ||||
SOST-related sclerosing bone dysplasia | Sosttm1(KOMP)Vlcg/Sosttm1(KOMP)Vlcg | involves: C57BL/6NTac | J:188586 | View | ||||
Transgenes and Other Mutations | SOST-related sclerosing bone dysplasia | Rr20tm1.1Vlcg/Rr20tm1.1Vlcg | involves: 129S6/SvEvTac * C57BL/6NTac | J:188586 | View | |||
SOST-related sclerosing bone dysplasia | Tg(RP11-209M4)AGglo/0 | FVB-Tg(RP11-209M4)4Gglo | J:99965 | View | ||||
SOST-related sclerosing bone dysplasia | Tg(RP11-209M4)AGglo/Tg(RP11-209M4)AGglo | FVB-Tg(RP11-209M4)4Gglo | J:99965 | View |
No similarity to the expected human disease phenotype was found.
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
NOT Models | Paget's disease of bone | Sqstm1tm1Jjw/Sqstm1tm1Jjw | involves: 129 * C57BL/6 | J:141179 | View |