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All mouse models of ocular cancer with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
 | uveal melanoma | Tg(Dct-Grm1)ESzc/0 | C57BL/6J-Tg(Dct-Grm1)ESzc | J:230115 | View | |||
 | retinoblastoma |
Rb1tm3Tyj/Rb1tm3Tyj Rbl1tm1Tyj/Rbl1tm1Tyj Tg(Pax6-cre,GFP)2Pgr/0 |
involves: 129S2/SvPas * 129S4/SvJae * 129X1/SvJ * C57BL/6 * FVB/N | J:119919 | View | |||
| retinoblastoma |
Rb1tm3Tyj/Rb1tm3Tyj Rbl2tm1Tyj/Rbl2tm1Tyj Tg(Nes-cre)1Atp/0 |
involves: 129S2/SvPas * 129S4/SvJae * FVB/N | J:91406 | View | ||||
| retinoblastoma |
Rb1tm3Tyj/Rb1tm3Tyj Rbl2tm2.1Tyj/Rbl2tm2.1Tyj Tg(Pax6-cre,GFP)2Pgr/0 |
involves: 129S4/SvJae * 129X1/SvJ * C57BL/6 * FVB/N | J:119919 | View | ||||
| Transgenes and Other Mutations | retinal cancer | Tg(Tyrp1-TAg)3434Bee/? | involves: BALB/c * C57BL/6J | J:75629 | View | |||
| retinoblastoma | Tg(Pax6-TAg)1796Hur/0 | involves: FVB | J:196814 | View | ||||
| retinoblastoma | Tg(Rbp3-SV40)IT-2Jjw/? | involves: BALB/c * C57BL/6 | J:60231 | View | ||||
| retinoblastoma | Tg(TagRb)1Plm/? | involves: BALB/cJ * C57BL/6J | J:10320 | View | ||||
| Additional Complex Models | uveal melanoma |
Cdkn2atm1Rdp/Cdkn2a+ X/Tg(Tyr-HRAS)60Lc |
involves: 129/Sv * C57BL/6J * CBA/J * FVB/N * SJL | J:140820 | View | |||
| uveal melanoma |
Gt(ROSA)26Sortm1(GNAQ*)Cvrk/Gt(ROSA)26Sor+ Tg(Mitf-cre)7114Gsb/0 |
C3FeJ.Cg-Gt(ROSA)26Sortm1(GNAQ*)Cvkr Tg(Mitf-cre)7114Gsb/Cvrk | J:225597 | View | ||||