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All mouse models of myeloproliferative neoplasm with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | essential thrombocythemia | DccTg(H2-Kb-Jak2*V617F)1Shmd/Dcc+ | involves: C57BL/6 * DBA/2 | J:130189 | View | |||
| essential thrombocythemia |
Jak2tm1(JAK2)Argr/Jak2+ Tg(Mx1-cre)1Cgn/0 |
involves: 129S7/SvEvBrd * C57BL/6 * CBA | J:164539 | View | ||||
| myeloproliferative neoplasm | Pdgfrbb2b2903Clo/Pdgfrbb2b2903Clo | C57BL/6J-Pdgfrbb2b2903Clo | J:175213 | View | ||||
| polycythemia vera | DccTg(H2-Kb-Jak2*V617F)1Shmd/Dcc+ | involves: C57BL/6 * DBA/2 | J:130189 | View | ||||
| polycythemia vera | Jak2tm1.1Jlvl/Jak2tm1.1Jlvl | involves: 129S2/SvPas * C57BL/6 | J:163497 | View | ||||
| polycythemia vera | Jak2tm1.2Ble/Jak2+ | involves: 129S6/SvEvTac * C57BL/6 * FVB/N | J:160883 | View | ||||
| polycythemia vera |
Jak2tm1.2Ble/Jak2+ Picalmtm1.1Tmae/Picalm+ Commd10Tg(Vav1-icre)A2Kio/Commd10+ |
involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * CBA * SJL | J:220728 | View | ||||
| polycythemia vera |
Jak2tm1Mohi/Jak2+ Tg(Mx1-cre)1Cgn/0 |
involves: C57BL/6 * CBA | J:183821 | View | ||||
| polycythemia vera |
Jak2tm1Mohi/Jak2tm1Mohi Tg(Mx1-cre)1Cgn/0 |
involves: C57BL/6 * CBA | J:183821 | View | ||||
| | essential thrombocythemia | Mybboo/Mybboo | involves: C57BL/6 | J:167270 | View | |||
| myeloproliferative neoplasm |
Jak2tm1.1Ble/Jak2+ Commd10Tg(Vav1-icre)A2Kio/Commd10+ |
involves: 129 * C57BL/6 * C57BL/10 * CBA/Ca | J:257910 | View | ||||
| myeloproliferative neoplasm | Tg(Vav1-Asxl1*Y588X)#Fcy/0 | C57BL/6-Tg(Vav1-Asxl1*Y588X)#Fcy | J:257690 | View | ||||
| | transient myeloproliferative syndrome |
Gata1tm1Mym/Gata1tm1Mym Tg(Gata1*)#Mym/0 |
involves: 129P2/OlaHsd * C57BL/6 * DBA/2J | J:158252 | View | |||
| transient myeloproliferative syndrome |
Gata1tm1Mym/Y Tg(Gata1*)#Mym/0 |
involves: 129P2/OlaHsd * C57BL/6 * DBA/2J | J:158252 | View | ||||
| Transgenes and Other Mutations | essential thrombocythemia |
Tg(JAK2*V617F)FF1Rsko/0 Commd10Tg(Vav1-icre)A2Kio/Commd10+ |
involves: C57BL/6 * C57BL/10 * CBA/Ca | J:134364 | View | |||
| essential thrombocythemia | Tg(Vav1-JAK2*V617F)AZjz/0 | involves: C57BL/6 * DBA/2 | J:135993 | View | ||||
| polycythemia vera |
Tg(JAK2*V617F)FF1Rsko/0 Tg(Mx1-cre)1Cgn/0 |
involves: C57BL/6 * CBA | J:134364 | View | ||||
| polycythemia vera | Tg(Vav1-JAK2*V617F)AZjz/0 | involves: C57BL/6 * DBA/2 | J:135993 | View | ||||
| Additional Complex Models | myeloproliferative neoplasm |
Col1a1tm2(tetO-GFP/RNAi:Smc1a)Iaai/Col1a1+ Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+ |
involves: 129S4/SvJae * C57BL/6 | J:229031 | View | |||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | essential thrombocythemia | Jak2tm1.1Jlvl/Jak2tm1.1Jlvl | involves: 129S2/SvPas * C57BL/6 | J:163497 | View | |||