Excel File Text File All mouse models of female reproductive system disease with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      ovarian cancer Amhr2tm3(cre)Bhr/Amhr2+
Ctnnb1tm1Mmt/Ctnnb1+
involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 J:186144 View
ovarian cancer Amhr2tm3(cre)Bhr/Amhr2+
Ctnnb1tm1Mmt/Ctnnb1+
Ptentm1Hwu/Ptentm1Hwu
involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 J:186144 View
ovarian cancer Ctnnb1tm1Mmt/Ctnnb1+
Krastm4Tyj/Kras+
Amhr2tm3(cre)Bhr/Amhr2+
involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 J:186144 View
ovarian cancer Ctnnb1tm1Mmt/Ctnnb1+
Krastm4Tyj/Kras+
Tg(CYP19A1-cre)1Jri/0
involves: 129S4/SvJae * 129X1/SvJ * C57BL/6 J:186144 View
ovarian cancer Ctnnb1tm1Mmt/Ctnnb1+
Ptentm1Hwu/Ptentm1Hwu
Tg(CYP19A1-cre)1Jri/0
involves: 129S4/SvJae * 129X1/SvJ * C57BL/6 J:186144 View
ovarian cancer Ctnnb1tm1Mmt/Ctnnb1+
Tg(CYP19A1-cre)1Jri/0
involves: 129X1/SvJ * C57BL/6 J:186144 View
primary ovarian insufficiency 12 Syce1em1Rrca/Syce1em1Rrca involves: C57BL/6J J:309952 View
primary ovarian insufficiency 13 Msh5em1Jzc/Msh5em1Jzc involves: C57BL/6 J:241778 View
primary ovarian insufficiency 19 Hsf2bpem2Amp/Hsf2bpem2Amp involves: C57BL/6J * CBA/J J:303558 View
      dermoid cyst of ovary Foxo3mommeR1/Foxo3mommeR1
Tg(HBA1-GFP)1Ew/Tg(HBA1-GFP)1Ew
FVB/NJ-Foxo3mommeR1 Tg(HBA1-Gfp)1Ew J:170710 View
endometrial cancer Errfi1tm1Jwj/Errfi1tm1Jwj
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129X1/SvJ J:150007 View
endometrial cancer Errfi1tm1Jwj/Errfi1tm1Jwj
Pgrtm2(cre)Lyd/Pgr+
Ptentm1Hwu/Ptentm1Hwu
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ J:162027 View
endometrial cancer Pgrtm2(cre)Lyd/Pgr+
Ptentm1Hwu/Ptentm1Hwu
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 J:139053 View
endometrial cancer Pgrtm2(cre)Lyd/Pgr+
Ptentm1Hwu/Ptentm1Hwu
Trp53tm1Brn/Trp53tm1Brn
involves: 129 * C57BL/6 J:139053 View
endometrial cancer Stk11tm1.1Rdp/Stk11tm1.1Rdp
Tg(Sprr2f-cre)1Dcas/0
involves: 129S6/SvEvTac * FVB/N J:158190 View
endometrial cancer Trp53tm1Brn/Trp53tm1Brn
Tg(Cdh16-cre)91Igr/0
involves: 129P2/OlaHsd * C57BL/6J * FVB/N * ICR J:214850 View
endometriosis Hdac3tm1.1Eno/Hdac3tm1.1Eno
Pgrtm2(cre)Lyd/Pgr+
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 J:269518 View
endometriosis Krastm4Tyj/Kras+ either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * C3H/HeJ) J:96296 View
female reproductive system disease Defb19em1Cya/Defb19em1Cya C57BL/6-Defb19em1Cya J:332576 View
ovarian cancer Apctm1Rsmi/Apctm1Rsmi
Pgrtm2(cre)Lyd/Pgr+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J J:210095 View
ovarian cancer Apctm1Tno/Apctm1Tno
Ptentm2Mak/Ptentm2Mak
involves: 129P2/OlaHsd * 129S4/SvJae J:120955 View
ovarian disease Patl2tm1b(EUCOMM)Hmgu/Patl2tm1b(EUCOMM)Hmgu involves: C57BL/6N * FVB/N J:264835 View
ovarian hyperstimulation syndrome Nr1h3tm1Djm/Nr1h3tm1Djm involves: 129S6/SvEvTac * C57BL/6 J:158168 View
placental insufficiency Emp2tm1.1Tac/Emp2tm1.1Tac
Tg(Zp3-cre)93Knw/0
involves: C57BL/6 * C57BL/6J * C57BL/6N J:243365 View
polycystic ovary syndrome Akt2tm1Hem/Akt2tm1Hem involves: 129P2/OlaHsd J:185012 View
primary ovarian insufficiency Fancftm1Nki/Fancftm1Nki involves: 129P2/OlaHsd * FVB J:180025 View
primary ovarian insufficiency Polr3hem2Cfe/Polr3hem2Cfe involves: C57BL/6J * SJL/J J:290735 View
uterine cancer Tg(H2-K-Hmga1)#Lmsr/0 involves: C57BL/6 * SJL J:121308 View
uterine fibroid Tsc2tm1.1Mjg/Tsc2tm1.1Mjg
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129X1/SvJ J:221228 View
      ovarian cancer Arid1atm1.1Mag/Arid1atm1.1Mag
Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/Gt(ROSA)26Sor+
involves: 129S6/SvEvTac * CD-1 J:219794 View
ovarian cancer Brca1tm1Brn/Brca1tm1Brn
Tg(Krt18-EGFP,-TAg121)36Ysng/0
Trp53tm1Brn/Trp53tm1Brn
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N J:189304 View
ovarian cancer Brca1tm1Brn/Brca1tm1Brn
Tg(Krt18-EGFP,-TAg121)36Ysng/0
Trp53tm1Brn/Trp53tm2Tyj
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N J:189304 View
ovarian cancer Brca2tm1Brn/Brca2tm1Brn
Tg(Krt18-EGFP,-TAg121)36Ysng/0
Trp53tm1Brn/Trp53tm2Tyj
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N J:189304 View
ovarian cancer Dicer1tm1Tara/Dicer1tm1Tara
Ptentm1Hwu/Ptentm1Hwu
Amhr2tm3(cre)Bhr/Amhr2+
involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd J:182161 View
ovarian cancer Dicer1tm1Tara/Dicer1tm1Tara
Ptentm1Hwu/Ptentm1Hwu
Trp53tm2Tyj/Trp53+
Amhr2tm3(cre)Bhr/Amhr2+
involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd J:222579 View
ovarian cancer Krastm4Tyj/Kras+
Ptentm1Hwu/Ptentm1Hwu
involves: 129S4/SvJae J:161953 View
ovarian cancer Krastm4Tyj/Kras+
Ptentm1Hwu/Ptentm1Hwu
involves: 129S4/SvJae * C57BL/6J J:96296 View
ovarian cancer Ptentm1Hwu/Ptentm1Hwu
Trp53tm2Tyj/Trp53+
Amhr2tm3(cre)Bhr/Amhr2+
involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd J:222579 View
Transgenes and
Other Mutations
     dermoid cyst of ovary Tg(Amh-SMAD2*)#Jebu/0 FVB/N-Tg(Amh-SMAD2*)#Jebu J:200783 View
endosalpingiosis Tg(Amh-SMAD2*)2Tkw/? involves: CD-1 J:129226 View
ovarian cancer Tg(Amhr2-SV40TAg)1Dcco/0 (C57BL/6 x C3H)F1 J:82550 View
ovarian cancer Tg(CAG-lacZ,-SV40)#Bcv/0 involves: FVB/N J:158388 View
polycystic ovary syndrome Tg(Cyp17a1-NGF)2456Oje/Tg(Cyp17a1-NGF)2456Oje involves: C57BL/6J * DBA/2J J:218686 View
Additional
Complex
Models
     female reproductive system disease Bgntm1Mfy/Bgntm1Mfy
Dcntm1Ioz/Dcntm1Ioz
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ J:180914 View
ovarian cancer Amhr2tm3(cre)Bhr/Amhr2+
Smad1tm2Rob/Smad1tm2.1Rob
Smad5tm1Huy/Smad5tm1Huy
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J J:157310 View
ovarian cancer Amhr2tm3(cre)Bhr/Amhr2+
Smad1tm2Rob/Smad1tm2Rob
Smad5tm1Huy/Smad5tm1Huy
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J J:157310 View
ovarian cancer Amhr2tm3(cre)Bhr/Amhr2+
Smad1tm2Rob/Smad1tm2Rob
Smad5tm1Huy/Smad5tm1Zuk
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J J:157310 View
ovarian cancer Cdkn1btm1Ako/Cdkn1b+
KitW-v/KitW-v
involves: 129S1/Sv * C57BL/6J J:236161 View
ovarian cancer Cdkn1btm1Ako/Cdkn1btm1Ako
KitW-v/KitW-v
involves: 129S1/Sv * C57BL/6J J:236161 View
ovarian cancer Foxo1tm1Rdp/Foxo1tm1.1Rdp
Foxo3tm1Rdp/Foxo3tm1.1Rdp
Amhr2tm3(cre)Bhr/Amhr2+
involves: 129S6/SvEvTac * 129S7/SvEvBrd J:232961 View
ovarian cancer Foxo1tm1Rdp/Foxo1tm1.1Rdp
Foxo3tm1Rdp/Foxo3tm1.1Rdp
Tg(CYP19A1-cre)1Jri/0
involves: 129S6/SvEvTac J:232961 View
ovarian cancer KitW-v/KitW-v
Trp53tm1Brn/Trp53tm1Brn
involves: 129P2/OlaHsd * C57BL/6J * FVB/N J:236161 View
ovarian cancer Rb1tm2Brn/Rb1tm2Brn
Trp53tm1Brn/Trp53tm1Brn
involves: 129P2/OlaHsd J:84345 View
ovarian cancer Tg(Krt18-EGFP,-TAg121)36Ysng/0
Trp53tm1Brn/Trp53tm1Brn
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N J:189304 View
ovarian cancer Tg(Krt18-EGFP,-TAg121)36Ysng/0
Trp53tm1Brn/Trp53tm2Tyj
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N J:189304 View
polycystic ovary syndrome Insrtm1Khn/Insrtm1Khn
Leprtm1.1Chua/Leprtm1.1Chua
Tg(Pomc1-cre)16Lowl/0
involves: 129 * 129S4/SvJae * 129S6/SvEvTac * C57BL/6J * FVB/N J:192274 View


       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      ovarian cancer Tg(Amhr2-Pik3ca*,-GFP)#Lzh/0 involves: C3H * C57BL/6 J:144834 View
primary ovarian insufficiency Helqem1Eljt/Helqem1Eljt C57BL/6J-Helqem1Eljt J:347863 View