Excel File Text File All mouse models of anemia with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      alpha thalassemia-X-linked intellectual disability syndrome Atrxtm1Rjg/Y
Foxg1tm1(cre)Skm/Foxg1+		 involves: 129P2/OlaHsd * C57BL/6 * FVB/N J:95953 View
alpha thalassemia-X-linked intellectual disability syndrome Atrxtm1Rjg/Y
Tg(Nes-cre)2472Pick/0		 involves: 129P2/OlaHsd * C57BL/6 * FVB/N J:95953 View
alpha thalassemia-X-linked intellectual disability syndrome Atrxtm1Rjg/Y
Tg(Pax6-cre,GFP)2Pgr/0		 involves: 129P2/OlaHsd * C57BL/6 * FVB/N J:145002 View
aplastic anemia Ifngtm1.1Hayg/Ifngtm1.1Hayg Not Specified J:220784 View
beta thalassemia Ahsptm1.1Mjwe/Ahsp+
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+		 involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 J:94421 View
beta thalassemia Ahsptm1.1Mjwe/Ahsptm1.1Mjwe
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+		 involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 J:94421 View
beta thalassemia Ahsptm1Mjwe/Ahsp+
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+		 involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 J:94421 View
beta thalassemia Ahsptm1Mjwe/Ahsptm1Mjwe
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+		 involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 J:94421 View
beta thalassemia Hbatm1(HBA)Tow/Hbatm1(HBA)Tow
Hbbtm2(HBG1,HBD,HBB*)Ryan/Hbbtm2(HBG1,HBD,HBB*)Ryan		 Not Specified J:148521 View
beta thalassemia Hbatm1(HBA)Tow/Hbatm1(HBA)Tow
Hbbtm2(HBG1,HBD,HBB*)Ryan/Hbbtm3(HBG1,HBB)Tow		 Not Specified J:148521 View
beta thalassemia Hbb-b1MommeD7/Hbb-b1MommeD7 involves: FVB/N J:190446 View
beta thalassemia Hbb-b1Rbc13/Hbb-b1Rbc13 involves: BALB/c * C57BL/6 J:190446 View
beta thalassemia Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+		 B6;129-Hbb-b1tm1Unc Hbb-b2tm1Unc/J J:211331 View
beta thalassemia Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+		 involves: 129P2/OlaHsd J:154187 View
beta thalassemia Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+		 involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 J:94421 View
beta thalassemia Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+		 involves: 129P2/OlaHsd * C57BL/6J J:30155 View
beta thalassemia Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+		 involves: 129P2/OlaHsd * C57BL/6N J:185154 View
beta thalassemia Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
Tg(HBB*)L2Pai/0		 involves: 129P2/OlaHsd * C57BL/6 J:97548 View
beta thalassemia Hbbd3th/Hbbd3th involves: C57BL/6 * DBA/2J J:7209 View
beta thalassemia Hbbtm1.1(HBG1,HBB*)Ryan/Hbb+ involves: C57BL/6J J:147906 View
beta thalassemia Hbbtm2Unc/Hbb+ involves: 129P2/OlaHsd * C57BL/6J J:64295 View
congenital nonspherocytic hemolytic anemia Gpi1b-m1Neu/Gpi1b-m1Neu C3.Cg-Gpi1b-m1Neu J:35956 View
congenital nonspherocytic hemolytic anemia Gpi1b-m2Neu/Gpi1b-m2Neu C3.Cg-Gpi1b-m2Neu J:35956 View
Diamond-Blackfan anemia 6 Rpl5Skax23-Jus/Rpl5+ 129S6.B6-Rpl5Skax23-Jus J:330162 View
Diamond-Blackfan anemia 7 Ndor1Tg(UBC-cre/ERT2)1Ejb/Ndor1+
Rpl11tm1.1Srn/Rpl11+		 involves: 129S6/SvEvTac * C57BL/6NCrl * CD-1 J:292575 View
Fanconi anemia complementation group A Fancatm1.1Wong/Fancatm1.1Wong involves: C57BL/6 J:85108 View
Fanconi anemia complementation group A Fancatm1Faw/Fancatm1Faw involves: 129P2/OlaHsd * FVB J:63742 View
Fanconi anemia complementation group A Fancatm1Wong/Fancatm1Wong involves: C57BL/6 J:85108 View
Fanconi anemia complementation group C Fancctm1Mab/Fancctm1Mab involves: 129S1/Sv * 129X1/SvJ * C57BL/6J J:32080 View
Fanconi anemia complementation group C Fancctm1Mgo/Fancctm1Mgo involves: 129S4/SvJaeSor * C57BL/6 J:61512 View
Fanconi anemia complementation group D1 Brca2tm1Kamc/Brca2tm1Kamc involves: 129P2/OlaHsd * BALB/c J:144998 View
Fanconi anemia complementation group D2 Aldh2tm1a(EUCOMM)Wtsi/Aldh2tm1a(EUCOMM)Wtsi
Fancd2tm1Hou/Fancd2tm1Hou		 involves: 129S4/SvJae * C57BL/6J * C57BL/6N J:193232 View
Fanconi anemia complementation group D2 Fancd2em1Tzh/Fancd2em1Tzh C57BL/6-Fancd2em1Tzh J:284566 View
Fanconi anemia complementation group D2 Fancd2Gt(OST57859)Lex/Fancd2Gt(OST57859)Lex
Usp1tm1.1Ada/Usp1tm1.1Ada		 involves: 129S5/SvEvBrd * C57BL/6 J:146616 View
Fanconi anemia complementation group D2 Fancd2tm1Hou/Fancd2tm1Hou 129S4/SvJae-Fancd2tm1Hou J:84892 View
Fanconi anemia complementation group D2 Fancd2tm1Hou/Fancd2tm1Hou B6.129S4-Fancd2tm1Hou J:84892 View
Fanconi anemia complementation group D2 Fancd2tm1Hou/Fancd2tm1Hou involves: 129S4/SvJae * C57BL/6J J:84892 View
hereditary spherocytosis type 1 Ank1M1Wlst/Ank1M1Wlst involves: 129S1/SvImJ * C3H/HeJ * C57BL/6 J:170562 View
hereditary spherocytosis type 1 Ank1nb/Ank1nb either: (involves: non-inbred stock) or (involves: C57BL/6) or (involves: WB/Re) J:11441 View
hereditary spherocytosis type 1 Ank1pale/Ank1pale C57BL/6J-Ank1pale/GrsrJ J:222308 View
hereditary spherocytosis type 1 Ank1Rbc2/Ank1Rbc2 involves: 129S1/Sv * BALB/c J:148127 View
hereditary spherocytosis type 3 Spta1ihj/Spta1ihj involves: HRS/J * LAH J:157766 View
hereditary spherocytosis type 3 Spta1sph-2Bc/Spta1sph-2Bc involves: SELH J:7048, J:7501 View
hereditary spherocytosis type 3 Spta1sph-ha/Spta1sph-ha involves: DBA/1J J:14946, J:30699 View
hereditary spherocytosis type 3 Spta1sph/Spta1sph either: (B6.C3-Spta1sph x WB.C3-Spta1sph)F1 or (WB.C3-Spta1sph x B6.C3-Spta1sph)F1 J:6695 View
hereditary spherocytosis type 3 Spta1sph/Spta1sph involves: C3H J:12276 View
pyruvate kinase deficiency of red cells Pklrchar4/Pklrchar4 involves: A/J * C57BL/6 J:86735 View
pyruvate kinase deficiency of red cells Pklrslc/Pklrslc CBA/NSlc-Pklrslc J:29199 View
      aplastic anemia Rasa3scat/Rasa3scat involves: BALB/cBy * BALB/cByJ J:281271 View
autoimmune hemolytic anemia Tg(KRT5-rtTA)1Glk/0
Tg(tetO/CMV-Tslp)#Sfz/0		 C.Cg-Tg(KRT5-rtTA)1Glk Tg(tetO/CMV-Tslp)#Sfz J:182756 View
beta thalassemia Klf1tm1Sho/Klf1tm1Sho involves: 129S4/SvJae * C57BL/6 J:25651 View
congenital dyserythropoietic anemia Diaph3tm1.1Pji/Diaph3tm1.1Pji
Tg(Mx1-cre)1Cgn/0		 involves: C57BL/6J * CBA/J J:293763 View
congenital dyserythropoietic anemia Man2a1tm1Jxm/Man2a1tm1Jxm involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:41621 View
Diamond-Blackfan anemia Flvcr1tm1.1Jlab/Flvcr1tm1.1Jlab involves: 129S4/SvJae * C57BL/6 * DBA/2 J:132057 View
Diamond-Blackfan anemia Flvcr1tm1Jlab/Flvcr1tm1Jlab
Tg(Mx1-cre)1Cgn/0		 involves: 129S4/SvJae * C57BL/6 * CBA J:132057 View
Diamond-Blackfan anemia Rpsatm1Ells/Rpsa+ involves: 129S6/SvEvTac * C57BL/6 J:138267 View
Fanconi anemia Usp1tm1.1Ada/Usp1tm1.1Ada C57BL/6-Usp1tm1.1Ada J:146616 View
hereditary spherocytosis Klf1Nan/Klf1+ either: B6.Cg-Klf1Nan or WB.Cg-Klf1Nan J:162530 View
hereditary spherocytosis type 1 Add2tm1Llp/Add2tm1Llp involves: 129S4/SvJae * C57BL/6J J:71029 View
hereditary spherocytosis type 1 Epb42tm1Llp/Epb42tm1Llp involves: 129P2/OlaHsd * C57BL/6J J:67412 View
hereditary spherocytosis type 1 Spta1sph-2Bc/Spta1sph-2Bc involves: SELH J:7048, J:7501 View
hereditary spherocytosis type 1 Spta1sph-ha/Spta1sph-ha involves: DBA/1J J:14946, J:30699 View
hereditary spherocytosis type 1 Spta1sph/Spta1sph involves: C3H J:12276 View
hereditary spherocytosis type 4 Slc4a1wan/Slc4a1wan C3H/HeJ-Slc4a1wan/J J:89043 View
macrocytic anemia KitW-v/KitW-v C57BL/6J-KitW-v/J J:243758 View
macrocytic anemia KitW/KitW-v involves: C57BL/6J J:243758 View
macrocytic anemia KitW/KitW B6.Cg-KitW/J J:243758 View
microcytic anemia Dnm2Rbc12/Dnm2+ involves: C57BL/6 J:330452 View
pancytopenia Nudt15em1Maska/Nudt15+ C57BL/6-Nudt15em1Maska J:285800 View
pancytopenia Nudt15em1Maska/Nudt15em1Maska C57BL/6-Nudt15em1Maska J:285800 View
sickle cell anemia Spta1sph-ha/Spta1sph-ha either: (B6.D1-Spta1sph-ha x WB.D1-Spta1sph-ha)F1 or (WB.D1-Spta1sph-ha x B6.D1-Spta1sph-ha)F1 J:12830 View
thalassemia Ppp1r15atm1.1Ajf/Ppp1r15atm1.1Ajf involves: 129 * C57BL/6 J:106905 View
      alpha thalassemia Hbab2(th)/Hba+ either: (involves: 101 * SEC) or (involves: 101 * C57BL * SEC) J:123943 View
alpha thalassemia Hbab2(th)/Hba+ involves: C57BL/6J * SEC J:32654 View
alpha thalassemia Hbab2(th)/Hba+ SEC-Hbab2(th) J:6452 View
alpha thalassemia Hbab3(th)/Hba+ either: (involves: 101 * SEC) or (involves: 101 * C57BL * SEC) J:123943 View
alpha thalassemia Hbab3(th)/Hba+ involves: C57BL/6J * SEC J:32654 View
alpha thalassemia Hbab3(th)/Hba+ SEC-Hbab3(th) J:6452 View
alpha thalassemia Hbath-J/Hba+ involves: C57BL/6J J:45721, J:32654 View
Diamond-Blackfan anemia Col1a1tm1(tetO-RNAi:Rps19)Karl/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae		 involves: 129S4/SvJae * C57BL/6 J:179085 View
Diamond-Blackfan anemia Col1a1tm1(tetO-RNAi:Rps19)Karl/Col1a1tm1(tetO-RNAi:Rps19)Karl
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae		 involves: 129S4/SvJae * C57BL/6 J:179085 View
Diamond-Blackfan anemia Col1a1tm2(tetO-RNAi:Rps19)Karl/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae		 involves: 129S4/SvJae * C57BL/6 J:179085 View
Diamond-Blackfan anemia Col1a1tm2(tetO-RNAi:Rps19)Karl/Col1a1tm2(tetO-RNAi:Rps19)Karl
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae		 involves: 129S4/SvJae * C57BL/6 J:179085 View
sickle cell anemia Hbatm1(HBA)Tow/Hbatm1(HBA)Tow
Hbbtm2(HBG1,HBB*)Tow/Hbbtm2(HBG1,HBB*)Tow		 Not Specified J:134980 View
sickle cell anemia Hbatm1(HBA)Tow/Hbatm1(HBA)Tow
Hbbtm2(HBG1,HBB*)Tow/Hbbtm2(HBG1,HBB*)Tow
Slc12a4Rbc10/Slc12a4+		 involves: 129 * BALB/c * C57BL/6J J:227339 View
sickle cell anemia Hbatm1Paz/Hbatm1Paz
Hbbtm1Tow/Hbbtm1Tow
Tg(HBA-HBBs)41Paz/?		 involves: 129S2/SvPas * 129S7/SvEvBrd * Black Swiss * C57BL/6 * DBA/2* FVB/N J:44161 View
sickle cell anemia Hbbd3th/Hbb+
Tg(HBB-AR-HBA2,-HBB*)58Rub/0
Tg(LCR-HBA2,LCR-HBB)11Cos/0		 involves: FVB/N * Swiss Webster J:94190 View
sickle cell anemia Hbbd3th/Hbb+
Tg(LCR-HBA1,LCR-HBB*)1Tow/0		 involves: C57BL/6 * DBA/2J * SJL J:127701 View
sickle cell anemia Hbbd3th/Hbb+
Tg(LCR-HBA2,LCR-HBB*)1Cos/0		 involves: C57BL/6J * CBA/J * DBA/2J J:94193 View
sickle cell anemia Hbbd3th/Hbbd3th
Tg(HBB-AR-HBA2,-HBB*)58Rub/0
Tg(LCR-HBA2,LCR-HBB)11Cos/0		 involves: FVB/N * Swiss Webster J:94190 View
Transgenes and
Other Mutations		     alpha thalassemia Hbatm1Ney/Hbatm1Ney either: (involves: 129P2/OlaHsd) or (involves: 129X1/SvJ) J:86682 View
beta thalassemia Hbbtm1Unc/Hbbtm1Unc involves: 129P2/OlaHsd * C57BL/6J J:4932 View
beta thalassemia Rr320tm1.1Mkg/Rr320+ involves: 129 J:60714 View
beta thalassemia Rr320tm2Mkg/Rr320tm2Mkg involves: 129S4/SvJaeSor J:28981 View
Diamond-Blackfan anemia Tg(CAG-RPS19*R62W)#Dmb/0
Tg(Prnp-GFP/cre)1Blw/0		 involves: 129S6/SvEvTac * FVB/N J:165876 View
Additional
Complex
Models		     autoimmune hemolytic anemia Tg(SV40-Igh-64C8)H3Hon/0
Tg(SV40-Igk4C8)L1Hon/0		 involves: C57BL/6 J:139864 View
hypochromic microcytic anemia Eps15tm1c(KOMP)Wtsi/Eps15tm1c(KOMP)Wtsi
Eps15l1tm2.1Noff/Eps15l1tm2.1Noff
Tg(Tek-cre)1Ywa/0		 involves: C57BL/6 * C57BL/6N * SJL J:272122 View

       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      beta thalassemia Del(7Or2h1-Rr320)1Mkg/+ involves: 129 J:139198 View
congenital dyserythropoietic anemia type III Kif23tm1.1Igo/Kif23+ involves: C57BL/6 * C57BL/6NTac J:321429 View
congenital dyserythropoietic anemia type III Kif23tm1.1Igo/Kif23tm1.1Igo involves: C57BL/6 * C57BL/6NTac J:321429 View
Fanconi anemia complementation group P Slx4tm1.2Jrou/Slx4tm1.2Jrou B6.129P2-Slx4tm1.2Jrou J:204996 View
Rh deficiency syndrome Rhagtm1Goo/Rhagtm1Goo involves: 129P2/OlaHsd * C57BL/6 J:182122 View
Rh deficiency syndrome Rhagtm1Goo/Rhagtm1Goo
Rhdtm1Goo/Rhdtm1Goo		 involves: 129P2/OlaHsd * C57BL/6 J:182122 View