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All mouse models of retinal vascular disease with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
diabetic retinopathy |
Insrtm1Khn/Insrtm1Khn Tg(Pdgfrb-cre)#Rha/0 |
involves: 129S4/SvJae * C57BL/6J | J:327000 | View | ||||
exudative vitreoretinopathy |
Cdh5tm1Dvst/Cdh5tm1Dvst Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0 |
involves: C57BL/6 * CBA | J:328283 | View | ||||
exudative vitreoretinopathy |
Ctnnb1em1V/Ctnnb1em1V Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0 |
involves: C57BL/6 * C57BL/6J * CBA | J:328283 | View | ||||
exudative vitreoretinopathy | Fzd4tm1Nat/Fzd4tm1Nat | involves: 129S1/Sv * 129X1/SvJ | J:158585 | View | ||||
exudative vitreoretinopathy | Fzd4tm1Nat/Fzd4tm1Nat | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:328283 | View | ||||
exudative vitreoretinopathy | Lrp5em1Xjz/Lrp5em1Xjz | C57BL/6J-Lrp5em1Xjz | J:328283 | View | ||||
exudative vitreoretinopathy | Lrp5r18/Lrp5r18 | C57BL/6J-Lrp5r18 | J:135279 | View | ||||
exudative vitreoretinopathy | Lrp5tm1Dgen/Lrp5tm1Dgen | B6.129P2-Lrp5tm1Dgen/J | J:235600 | View | ||||
exudative vitreoretinopathy | Lrp5tm1Dgen/Lrp5tm1Dgen | involves: 129P2/OlaHsd * C57BL/6 | J:328283 | View | ||||
exudative vitreoretinopathy | Ndptm1Wbrg/Y | involves: 129P2/OlaHsd * C57BL/6 | J:158585 | View | ||||
exudative vitreoretinopathy | Tspan12tm1Wye/Tspan12tm1Wye | either: B6.129S5-Tspan12tm1Wye or FVB.129S5-Tspan12tm1Wye | J:158585 | View | ||||
retinal vein occlusion | Nrp1tm1.1Cruh/Nrp1tm1.1Cruh | involves: C57BL/6 | J:176047 | View | ||||
severe nonproliferative diabetic retinopathy | Pdgfrbredeye/Pdgfrbredeye | C3N.C-Pdgfrbredeye | J:199483 | View | ||||
Additional Complex Models | exudative vitreoretinopathy |
Ctnna1em1Xjz/Ctnna1tm1Efu Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0 |
involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * C57BL/6J * C57BL/6NCrl * CBA | J:328283 | View | |||
exudative vitreoretinopathy |
Ctnna1tm1Efu/Ctnna1tm1Efu Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0 |
involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * C57BL/6NCrl * CBA | J:328283 | View |