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All mouse models of psychotic disorder with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
schizophrenia | Akt1tm1Mbb/Akt1tm1Mbb | involves: 129P2/OlaHsd * C57BL/6 | J:185487 | View | ||||
schizophrenia | Chrna7tm1Bay/Chrna7tm1Bay | B6.129S7-Chrna7tm1Bay/J | J:214099 | View | ||||
schizophrenia | Disc1m1H/Disc1m1H | B6N.C(C3H)-Disc1m1H | J:229661 | View | ||||
schizophrenia | Disc1Rgsc1390/Disc1Rgsc1390 | B6.Cg-Disc1Rgsc1390 | J:120634 | View | ||||
schizophrenia | Disc1tm1(DISC1/DISC1FP1,DISC1FP1/DISC1,DISC1)Xzho/Disc1del | 129S2/SvPasCrl-Disc1del Disc1tm1(DISC1/DISC1FP1,DISC1FP1/DISC1,DISC1)Xzho | J:214737 | View | ||||
schizophrenia | Disc1tm1Kara/Disc1+ | B6.129S6-Disc1tm1Kara | J:107244 | View | ||||
schizophrenia | Disc1tm1Kara/Disc1tm1Kara | B6.129S6-Disc1tm1Kara | J:107244 | View | ||||
schizophrenia | Dtnbp1sdy/Dtnbp1sdy | B6J.D2-Dtnbp1sdy | J:197066, J:223954 | View | ||||
schizophrenia | Dtnbp1sdy/Dtnbp1sdy | DBA/2J-Dtnbp1sdy/J | J:143912 | View | ||||
schizophrenia |
Ncstntm1.1Sud/Ncstntm1.1Sud Olig1tm1(cre)Rth/Olig1+ |
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ | J:234705 | View | ||||
schizophrenia | Tg(Camk2a-ESR1/Disc1*)2698.1Sva/0 | involves: C57BL/6 * C57BL/6NTac | J:127235 | View | ||||
schizophrenia | Tg(Disc1/EGFP)M19Sshe/0 | involves: C57BL/6JCrl * CBA/CaCrl | J:143557 | View | ||||
schizoaffective disorder | Gria1tm1Rsp/Gria1tm1Rsp | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:167264 | View | ||||
schizoaffective disorder | Gria1tm1Rsp/Gria1tm1Rsp | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J | J:167264 | View | ||||
schizophrenia | Avpr1atm1Dgen/Avpr1atm1Dgen | involves: 129P2/OlaHsd * C57BL/6 | J:101679 | View | ||||
schizophrenia | Bace1tm1Pcw/Bace1tm1Pcw | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:133643 | View | ||||
schizophrenia | Chst3tm1Dgen/Chst3tm1Dgen | involves: 129P2/OlaHsd * C57BL/6 | J:101679 | View | ||||
schizophrenia | ckr/ckr | involves: C3H/HeRos * C57BL/10Ros | J:87399 | View | ||||
schizophrenia | Cplx2tm1Bros/Cplx2tm1Bros | B6NCrl.Cg-Cplx2tm1Bros | J:175056 | View | ||||
schizophrenia | Csmd1tm1Lex/Csmd1tm1Lex | involves: 129S5/SvEvBrd * C57BL/6NTac | J:209700 | View | ||||
schizophrenia | Ctsctm1Dgen/Ctsctm1Dgen | involves: 129P2/OlaHsd * C57BL/6 | J:101679 | View | ||||
schizophrenia | Grin1tm1Bhk/Grin1tm1Bhk | involves: 129P2/OlaHsd * C57BL/6 * DBA/2 | J:57125 | View | ||||
schizophrenia | Grm5tm1Rod/Grm5tm1Rod | B6.129-Grm5tm1Rod | J:268239 | View | ||||
schizophrenia | Hivep2tm1Sis/Hivep2tm1Sis | either: (involves: BALB/cA * C57BL/6NCrlj * CBA/JNCrlj) or (involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj) | J:263351 | View | ||||
schizophrenia | Hivep2tm1Sis/Hivep2tm1Sis | involves: C57BL/6NCrlj * CBA/JNCrlj | J:271912 | View | ||||
schizophrenia | Kif3btm1Noh/Kif3b+ | involves: 129S4/SvJae * C57BL/6J | J:286227 | View | ||||
schizophrenia | Lrrtm1tm1.1Jaru/Lrrtm1tm1.1Jaru | involves: C57BL/6 * C57BL/6J | J:174350 | View | ||||
schizophrenia | Map2k7tm1Pngr/Map2k7+ | involves: 129P2/OlaHsd * C57BL/6J | J:188339 | View | ||||
schizophrenia | Map6tm1Job/Map6+ | involves: 129S2/SvPas * C57BL/6 | J:225083 | View | ||||
schizophrenia | Map6tm1Job/Map6tm1Job | either: 129S2/SvPas or (involves: 129S2/SvPas * BALB/c) | J:79099 | View | ||||
schizophrenia | Map6tm1Job/Map6tm1Job | involves: 129S2/SvPas * C57BL/6 | J:225083 | View | ||||
schizophrenia | Mdktm1Tmu/Mdktm1Tmu | B6.129S2-Mdktm1Tmu | J:151029 | View | ||||
schizophrenia | Nlgn2tm1.1Gchn/Nlgn2tm1.1Gchn | involves: 129S/SvEv * C57BL/6J | J:272181 | View | ||||
schizophrenia | Nr4a2tm1Tpe/Nr4a2+ | B6.129P2-Nr4a2tm1Tpe | J:147544 | View | ||||
schizophrenia | Nrg1tm2Zhou/Nrg1+ | involves: 129S4/SvJae * C57BL/6 | J:81106 | View | ||||
schizophrenia | Nrg3tm1.1Plet/Nrg3tm1.1Plet | involves: C57BL/6 | J:270199 | View | ||||
schizophrenia | Nrxn1tm1Sud/Nrxn1tm1Sud | involves: 129 * C57BL/6 | J:153748 | View | ||||
schizophrenia |
Pdgfrbtm1Msas/Pdgfrbtm1Msas Tg(Nes-cre)1Nogu/0 |
B6J.Cg-Pdgfrbtm1Msas Tg(Nes-cre)1Nogu | J:229179 | View | ||||
schizophrenia | Plcb1tm1Hssh/Plcb1tm1Hssh | involves: 129/Sv * C57BL/6 | J:151070 | View | ||||
schizophrenia | Pparaem1Tyrb/Pparaem1Tyrb | C57BL/6J-Pparaem1Tyrb | J:313946 | View | ||||
schizophrenia | Ppm1gtm1Dgen/Ppm1g+ | involves: 129P2/OlaHsd * C57BL/6 | J:101679 | View | ||||
schizophrenia |
Ppp3r1tm1Stl/Ppp3r1tm1Stl Tg(Camk2a-cre)CW2Stl/0 |
C57BL/6-Ppp3r1tm1Stl Tg(Camk2a-cre)CW2Stl | J:73203, J:84640 | View | ||||
schizophrenia | Relnrl/Reln+ | B6.Cg-Relnrl | J:223944 | View | ||||
schizophrenia | Relnrl/Reln+ | B6C3Fe a/a-Relnrl/J | J:107996 | View | ||||
schizophrenia | Setd1aem1Yzhg/Setd1a+ | B6.Cg-Setd1aem1Yzhg | J:328716 | View | ||||
schizophrenia | Shank3tm4.1Gfng/Shank3tm4.1Gfng | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:230887 | View | ||||
schizophrenia | Slc6a1tm1Mlit/Slc6a1tm1Mlit | B6.129S1-Slc6a1tm1Mlit | J:204368 | View | ||||
schizophrenia | Slc6a3tm1Mca/Slc6a3tm1Mca | involves: 129P2/OlaHsd | J:31328 | View | ||||
schizophrenia | Snap25Bdr/Snap25+ | involves: BALB/cAnNCrl | J:119733 | View | ||||
schizophrenia | Sp4tm3(Sp4)Krc/Sp4tm3(Sp4)Krc | involves: 129S1/Sv * 129X1/SvJ * Black Swiss | J:163637 | View | ||||
schizophrenia | Srgap3tm1.1Zi/Srgap3tm1.1Zi | B6.129(SJL)-Srgap3tm1.1Zi | J:192388 | View | ||||
schizophrenia | Srrrgsc1872/Srrrgsc1872 | C57BL/6JJcl-Srrrgsc1872 | J:151337 | View | ||||
schizophrenia | Srrtm1.2Jtc/Srrtm1.2Jtc | involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 | J:158266 | View | ||||
schizophrenia | Syngap1tm1Rlh/Syngap1+ | involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J | J:194146 | View | ||||
schizophrenia | Taar1tm1Tdw/Taar1tm1Tdw | involves: 129S1/Sv * C57BL/6J | J:141501 | View | ||||
schizophrenia | Tg(Camk2a-Magi2)1Shlee/? | C57BL/6J-Tg(Camk2a-Magi2)1Shlee | J:218971 | View | ||||
schizophrenia |
Tg(Camk2a-tTA)1Mmay/0 Tg(tetO-Gnas)1593Mpke/0 |
B6.Cg-Tg(Camk2a-tTA)1Mmay Tg(tetO-Gnas)1593Mpke | J:166114 | View | ||||
schizophrenia | Tg(Thy1-Tcf4)1Mjro/0 | involves: C57BL/6N * FVB/N | J:197081 | View | ||||
schizophrenia | YwhazGt(OST432062)Lex/YwhazGt(OST432062)Lex | either: B6.129S5-YwhazGt(OST432062)Lex or C.129S5-YwhazGt(OST432062)Lex or (involves: 129S5/SvEvBrd * 129T2/SvEmsWehi)) | J:217297 | View | ||||
schizophrenia | Zfp521tm1Nohk/Zfp521tm1Nohk | B6J.Cg-Zfp521tm1Nohk | J:214267 | View | ||||
schizophrenia | Zfp804aem1Yqd/Zfp804aem1Yqd | involves: C57BL/6 * FVB/N | J:312498 | View | ||||
schizophrenia | Zic2tm1Jaru/Zic2+ | involves: 129S4/SvJae * C57BL/6J | J:174352 | View | ||||
schizophrenia | Del(16Dgcr2-Hira)3Aam/+ | involves: 129S7/SvEvBrd * C57BL/6J | J:158957 | View | ||||
Transgenes and Other Mutations | schizophrenia | Tg(Camk2a-DISC1)10Asaw/0 | C57BL/6-Tg(Camk2a-DISC1)10Asaw | J:124683, J:194985 | View | |||
schizophrenia | Tg(Camk2a-DISC1)37Asaw/0 | C57BL/6-Tg(Camk2a-DISC1)37Asaw | J:124683, J:194985 | View | ||||
schizophrenia | Tg(Camk2a-DISC1)37Asaw/Tg(Camk2a-DISC1)37Asaw | C57BL/6-Tg(Camk2a-DISC1)37Asaw | J:194985 | View | ||||
schizophrenia |
Tg(Eno2tTA)5030Nes/0 Tg(tetO-NRG1_i4)6Ajla/0 |
involves: C57BL/6 * C57BL/6J * SJL | J:231737 | View | ||||
schizophrenia |
Tg(GFAP-tTA)6Hyms/0 Tg(tetO-HMOX1)6Hyms/0 |
involves: FVB/N | J:186620 | View | ||||
schizophrenia 9 |
Tg(Camk2a-tTA)1Mmay/0 Tg(tetO-DISC1*)1001Plet/0 |
involves: C57BL/6 * CBA * SJL | J:146881 | View | ||||
schizophrenia 9 |
Tg(tetO-DISC1*)70Plet/0 Tg(Camk2a-tTA)1Mmay/0 |
involves: C57BL/6 * CBA * SJL | J:146881 | View |
No similarity to the expected human disease phenotype was found.
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
NOT Models | schizophrenia | Csmd1tm1Lex/Csmd1tm1Lex | B6;129S5-Csmd1tm1Lex/Mmucd | J:194991 | View | |||
schizophrenia | Rtn4rrgsc1836/Rtn4rrgsc1836 | C57BL/6JJcl-Rtn4rrgsc1836 | J:176996 | View | ||||
schizophrenia | Rtn4rtm1Gogo/Rtn4rtm1Gogo | involves: 129 * C57BL/6J | J:130368 | View |