Excel File Text File All mouse models of hematologic cancer with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      acute myeloid leukemia Cebpatm8.1Nerl/Cebpatm8.1Nerl involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 J:136134 View
acute myeloid leukemia Crebbptm1Dli/Crebbp+ involves: 129S6/SvEvTac * C57BL/6 J:60630 View
acute myeloid leukemia Flt3tm1.1Dosm/Flt3+ B6.129(C)-Flt3tm1.1Dosm J:205200 View
acute myeloid leukemia Flt3tm1Dgg/Flt3+
Kmt2atm1Clgr/Kmt2a+
involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6J J:189096 View
acute myeloid leukemia Flt3tm1Dgg/Flt3tm1Dgg
Kmt2atm1Clgr/Kmt2a+
involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6J J:189096 View
acute myeloid leukemia Flt3tm2.1Dosm/Flt3+ B6.129(C)-Flt3tm2.1Dosm J:205200 View
acute myeloid leukemia Kmt2atm1Saam/Kmt2a+
Tg(Mx1-cre)1Cgn/0
involves: 129S1/Sv * C57BL/6 * CBA J:140628 View
acute myeloid leukemia Kmt2atm2(MLLT3)Thr/Kmt2a+ involves: 129P2/OlaHsd J:56340 View
acute myeloid leukemia Tg(Vav1-Asxl1*Y588X)#Fcy/0 C57BL/6-Tg(Vav1-Asxl1*Y588X)#Fcy J:257690 View
B-cell lymphoma Ezh2tm1.1Nesh/Ezh2+
Cd19tm1(cre)Cgn/Cd19+
involves: 129 * 129P2/OlaHsd * C57BL/6 J:239472 View
Burkitt lymphoma Ightm1(Myc)Janz/Igh+ involves: 129X1/SvJ * C57BL/6 J:96785 View
Burkitt lymphoma Myctm1Lbox/Myc+ involves: 129S1/Sv * 129X1/SvJ * FVB/N J:97900 View
Burkitt lymphoma Myctm1Lbox/Myctm1Lbox involves: 129S1/Sv * 129X1/SvJ * FVB/N J:97900 View
Burkitt lymphoma Tg(IghMyc)22Bri/0 involves: C57BL/6 * SJL J:78177, J:186117 View
essential thrombocythemia DccTg(H2-Kb-Jak2*V617F)1Shmd/Dcc+ involves: C57BL/6 * DBA/2 J:130189 View
essential thrombocythemia Jak2tm1(JAK2)Argr/Jak2+
Tg(Mx1-cre)1Cgn/0
involves: 129S7/SvEvBrd * C57BL/6 * CBA J:164539 View
juvenile myelomonocytic leukemia Nf1tm1Fcr/Nf1+
Ptentm1Hwu/Ptentm1Hwu
Tg(Mx1-cre)1Cgn/0
B6.Cg-Tg(Mx1-cre)1Cgn Nf1tm1Fcr Ptentm1Hwu J:232645 View
juvenile myelomonocytic leukemia Nf1tm1Par/Nf1tm1Par
Tg(Mx1-cre)1Cgn/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA J:90973 View
juvenile myelomonocytic leukemia Ptpn11tm6Bgn/Ptpn11+
Tg(Mx1-cre)1Cgn/0
involves: 129S6/SvEvTac * C57BL/6 * CBA J:148430 View
myelodysplastic syndrome Asxl1tm1.1Iaai/Asxl1tm1.1Iaai
Tg(Mx1-cre)1Cgn/0
involves: 129S/SvEv * C57BL/6 * CBA J:208092 View
myelodysplastic syndrome Asxl1tm1.1Iaai/Asxl1tm1.1Iaai
Tg(VAV1-cre)1Graf/0
involves: 129S/SvEv * C57BL/6 J:208092 View
myelodysplastic syndrome Asxl1tm1.1Mjxu/Asxl1+ involves: 129 * C57BL/6 J:208085 View
myelodysplastic syndrome Asxl1tm1.1Mjxu/Asxl1tm1.1Mjxu involves: 129 * C57BL/6 J:208085 View
myelodysplastic syndrome Sf3b1tm1.1Mdf/Sf3b1+
Tet2tm1.1Iaai/Tet2tm1.1Iaai
Tg(Mx1-cre)1Cgn/?
involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * CBA/J J:234976 View
myelodysplastic syndrome Sf3b1tm1Hko/Sf3b1+ Not Specified J:324276 View
myelodysplastic syndrome Srsf2tm1.1Oaw/Srsf2+
Tg(Mx1-cre)1Cgn/?
B6.Cg-Tg(Mx1-cre)1Cgn Srsf2tm1.1Oaw J:221404 View
myelodysplastic syndrome Tg(Vav1-Asxl1*Y588X)#Fcy/0 C57BL/6-Tg(Vav1-Asxl1*Y588X)#Fcy J:257690 View
myelofibrosis Jak2tm1.1Jlvl/Jak2tm1.1Jlvl involves: 129S2/SvPas * C57BL/6 J:163497 View
myelofibrosis Tg(H2-Kb-Jak2*V617F)2Shmd/0 involves: C57BL/6 * DBA/2 J:130189 View
myeloproliferative neoplasm Pdgfrbb2b2903Clo/Pdgfrbb2b2903Clo C57BL/6J-Pdgfrbb2b2903Clo J:175213 View
polycythemia vera DccTg(H2-Kb-Jak2*V617F)1Shmd/Dcc+ involves: C57BL/6 * DBA/2 J:130189 View
polycythemia vera Jak2tm1.1Jlvl/Jak2tm1.1Jlvl involves: 129S2/SvPas * C57BL/6 J:163497 View
polycythemia vera Jak2tm1.2Ble/Jak2+ involves: 129S6/SvEvTac * C57BL/6 * FVB/N J:160883 View
polycythemia vera Jak2tm1.2Ble/Jak2+
Picalmtm1.1Tmae/Picalm+
Commd10Tg(Vav1-icre)A2Kio/Commd10+
involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * CBA * SJL J:220728 View
polycythemia vera Jak2tm1Mohi/Jak2+
Tg(Mx1-cre)1Cgn/0
involves: C57BL/6 * CBA J:183821 View
polycythemia vera Jak2tm1Mohi/Jak2tm1Mohi
Tg(Mx1-cre)1Cgn/0
involves: C57BL/6 * CBA J:183821 View
      acute lymphoblastic leukemia Ezh2tm2Sho/Ezh2tm2.1Sho
Tg(Mx1-cre)1Cgn/0
involves: 129S1/Sv * C57BL/6 * CBA J:182211 View
acute lymphoblastic leukemia Ezh2tm2Sho/Ezh2tm2Sho
Tg(Mx1-cre)1Cgn/0
involves: 129S1/Sv * C57BL/6 * CBA J:182211 View
acute lymphoblastic leukemia Kmt2atm1Saam/Kmt2a+
Tg(Mx1-cre)1Cgn/0
involves: 129S1/Sv * C57BL/6 * CBA J:140628 View
acute lymphoblastic leukemia Ptentm1Hwu/Ptentm1Hwu
Tg(Mx1-cre)1Cgn/0
involves: 129S4/SvJae * C57BL/6 * CBA J:169097 View
acute lymphoblastic leukemia Tg(CD2-Lmo2)#Thr/0 involves: C57BL/6 * CBA J:102058 View
acute lymphoblastic leukemia Tg(Lck-Notch3)#Issc/0 involves: C57BL/6 * DBA/2 J:63300 View
acute myeloid leukemia Arid4atm1Alb/Arid4atm1Alb involves: 129S7/SvEvBrd J:141004 View
acute myeloid leukemia Arid4atm1Alb/Arid4atm1Alb
Arid4btm1Alb/Arid4b+
involves: 129S7/SvEvBrd J:141004 View
acute myeloid leukemia Mybl2tm1.1Jof/Mybl2+
Tg(Zp3-cre)3Mrt/0
involves: 129S2/SvPas * C57BL/6 * FVB/N J:196804 View
acute myeloid leukemia Spi1tm1.3Dgt/Spi1tm1.3Dgt involves: 129 * BALB/c * C57BL/6 J:90331 View
chronic myeloid leukemia Chordc1tm1Mbra/Chordc1+ involves: 129 * C57BL/6 J:222040 View
chronic myeloid leukemia Ncstntm1.1Akli/Ncstntm1.1Akli
Tg(Mx1-cre)1Cgn/0
involves: 129 * C57BL/6 * CBA * SJL J:172442 View
chronic myeloid leukemia Ncstntm1.1Akli/Ncstntm1.1Akli
Tg(VAV1-cre)1Graf/0
involves: 129 * C57BL/6 * SJL J:172442 View
chronic myeloid leukemia Sh2b3tm1Paw/Sh2b3tm1Paw involves: 129S1/Sv * 129X1/SvJ J:161643 View
chronic myeloid leukemia Sipa1tm1Nm/Sipa1+ involves: 129P2/OlaHsd * C57BL/6 J:97239 View
chronic myeloid leukemia Sipa1tm1Nm/Sipa1tm1Nm involves: 129P2/OlaHsd * C57BL/6 J:97239 View
chronic myelomonocytic leukemia Kdm6atm1Cdcn/Kdm6atm1Cdcn
Tg(CAG-cre/Esr1*)5Amc/0
involves: C57BL/6J * CBA J:263565 View
chronic myelomonocytic leukemia Kdm6atm1Cdcn/Y
Tg(CAG-cre/Esr1*)5Amc/0
involves: C57BL/6J * CBA J:263565 View
diffuse large B-cell lymphoma Smurf2Gt(RRA098)Byg/Smurf2Gt(RRA098)Byg involves: 129P2/OlaHsd * C57BL/6 J:245679 View
diffuse large B-cell lymphoma Trp53tm1.2Awbr/Trp53tm1.2Awbr involves: C57BL/6 J:173271 View
diffuse large B-cell lymphoma Trp53tm1Tyj/Trp53tm1Tyj
Tg(Ly6e-MALT1)#Isg/0
involves: 129S2/SvPas * C57BL/6 * CBA J:185590 View
essential thrombocythemia Mybboo/Mybboo involves: C57BL/6 J:167270 View
familial chronic myelocytic leukemia-like syndrome Irf8myls/Irf8myls
Slc11a1r/Slc11a1r
BXH2/TyJ J:97931 View
familial chronic myelocytic leukemia-like syndrome Irf8myls/Irf8myls
Slc11a1r/Slc11a1r
involves: A/J * BXH2/TyJ J:97931 View
familial chronic myelocytic leukemia-like syndrome Irf8tm1Hor/Irf8+ either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6) J:36038 View
familial chronic myelocytic leukemia-like syndrome Irf8tm1Hor/Irf8tm1Hor either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6) J:36038 View
follicular lymphoma Rarres1tm1.2Mhl/Rarres1+ involves: 129S1/SvImJ * C57BL/6 * FVB/N * NIH Black Swiss J:324270 View
follicular lymphoma Rarres1tm1.2Mhl/Rarres1tm1.2Mhl involves: 129S1/SvImJ * C57BL/6 * FVB/N * NIH Black Swiss J:324270 View
follicular lymphoma Rarres1tm1d(KOMP)Wtsi/Rarres1+ involves: C57BL/6N J:324270 View
juvenile myelomonocytic leukemia Flt3tm1Dgg/Flt3+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:126003 View
juvenile myelomonocytic leukemia Flt3tm1Dgg/Flt3tm1Dgg involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:126003 View
juvenile myelomonocytic leukemia Krastm4Tyj/Kras+
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Tg(Flt3-cre)#Ccb/0
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 J:247853 View
juvenile myelomonocytic leukemia Krastm4Tyj/Kras+
Tg(Mx1-cre)1Cgn/0
involves: 129S4/SvJae * BALB/c * C57BL/6 * CBA J:88163 View
juvenile myelomonocytic leukemia Krastm4Tyj/Kras+
Tg(Mx1-cre)1Cgn/0
involves: 129S4/SvJae * C57BL/6 * CBA J:87429, J:115071 View
lymphoid leukemia Tg(Lck-Tal1)4709Led/0 FVB/N-Tg(Lck-Tal1)4709Led J:36076 View
lymphoma Gt(ROSA)26Sortm1(tTA,tetO-Mir155)Fjsl/Gt(ROSA)26Sor+
Tg(Nes-cre)1Wmz/0
involves: 129 * C57BL/6 * FVB/N * SJL/J J:185598 View
lymphoma Tg(H2-K-Hmga1)#Lmsr/0 involves: C57BL/6 * SJL J:90252 View
multiple myeloma Tg(Igh-Maf)68Staka/0 C57BL/6-Tg(Igh-Maf)68Staka J:168074 View
multiple myeloma Tg(Igh-Maf)524Staka/0 involves: C57BL/6 * C57BL/6J * DBA/2 J:168074 View
myelodysplastic syndrome Atg7tm1Tchi/Atg7tm1Tchi
Commd10Tg(Vav1-icre)A2Kio/Commd10+
involves: C57BL/6NCrlj * C57BL/10 * CBA/Ca * CBA/JNCrlj J:176843 View
myelodysplastic syndrome Bap1tm1.1Geno/Bap1tm1.1Geno
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
involves: C57BL/6 * C57BL/6NTac J:187380 View
myelodysplastic syndrome Crebbptm1Dli/Crebbp+ involves: 129S6/SvEvTac * C57BL/6 J:191503 View
myelodysplastic syndrome Egr1tm1Jmi/Egr1tm1Jmi involves: 129 * C57BL/6 J:123870 View
myelodysplastic syndrome Gata1tm1Mym/Gata1+ involves: 129P2/OlaHsd J:88685 View
myelodysplastic syndrome Macroh2a1tm1.1Oxbo/Macroh2a1tm1.1Oxbo B6.Cg-Macroh2a1tm1.1Oxbo J:293382 View
myelodysplastic syndrome Mybl2tm1.1Jof/Mybl2+
Tg(Zp3-cre)3Mrt/0
involves: 129S2/SvPas * C57BL/6 * FVB/N J:196804 View
myelodysplastic syndrome Npm1tm1Ppp/Npm1+ involves: 129S1/Sv * C57BL/6 J:101494 View
myelodysplastic syndrome Polgtm1Prol/Polgtm1Prol B6J.129S7-Polgtm1Prol J:154187 View
myelodysplastic syndrome Samd9ltm1Homy/Samd9l+ involves: 129P2/OlaHsd J:202604 View
myelodysplastic/myeloproliferative neoplasm Dido1tm1Cmar/Dido1tm1Cmar involves: 129S1/Sv * 129X1/SvJ J:101201 View
myelofibrosis Gata1tm2Sho/Gata1tm2Sho involves: 129S4/SvJae * C57BL/6 * CD-1 J:78348 View
myelofibrosis Gata1tm2Sho/Y involves: 129S4/SvJae * C57BL/6 * CD-1 J:78348 View
myelofibrosis Mybboo/Mybboo involves: C57BL/6 J:167270 View
myelofibrosis Ncor2tm1Rev/Ncor2tm1Rev involves: 129/Sv * C57BL/6 J:202976 View
myeloproliferative neoplasm Jak2tm1.1Ble/Jak2+
Commd10Tg(Vav1-icre)A2Kio/Commd10+
involves: 129 * C57BL/6 * C57BL/10 * CBA/Ca J:257910 View
myeloproliferative neoplasm Tg(Vav1-Asxl1*Y588X)#Fcy/0 C57BL/6-Tg(Vav1-Asxl1*Y588X)#Fcy J:257690 View
non-Hodgkin lymphoma Mtss1Gt(CSC156)Byg/Mtss1Gt(CSC156)Byg B6.129P2-Mtss1Gt(CSC156)Byg J:186118 View
non-Hodgkin lymphoma S1pr2tm1Ajml/S1pr2tm1Ajml 129S5/SvEvBrd-S1pr2tm1Ajml J:154439 View
non-Hodgkin lymphoma S1pr2tm1Ajml/S1pr2tm1Ajml involves: 129S5/SvEvBrd * C57BL/6 J:154439 View
peripheral T-cell lymphoma Rc3h1san/Rc3h1+ involves: C57BL/6JSfdAnu J:189087 View
T-cell acute lymphoblastic leukemia Nbnem7Jpt/Nbntm2Zqw
Tg(VAV1-cre)1Graf/0
involves: 129P2/OlaHsd J:277750 View
T-cell acute lymphoblastic leukemia Tg(H2-K-Hmga1)#Lmsr/0 involves: C57BL/6 * SJL J:90252 View
T-cell adult acute lymphocytic leukemia Gt(ROSA)26Sortm18(Zeb2)Jhai/Gt(ROSA)26Sortm18(Zeb2)Jhai
Tg(Cd4-cre)1Cwi/0
involves: C57BL/6 * CD-1 * DBA/2 J:263520 View
T-cell adult acute lymphocytic leukemia Gt(ROSA)26Sortm18(Zeb2)Jhai/Gt(ROSA)26Sortm18(Zeb2)Jhai
Tg(Tek-cre)1Ywa/0
involves: C57BL/6 * CD-1 * SJL J:263520 View
T-cell adult acute lymphocytic leukemia Tg(Lck-Tax)53Hall/0 involves: C57BL/6 J:129531, J:214623 View
      acute lymphoblastic leukemia Ikzf1tm1Kast/Ikzf1+
Tg(BCR/ABL)623Hkp/0
involves: 129S2/SvPas * C57BL/6 * CBA J:160846 View
acute promyelocytic leukemia Pmltm1.1Ews/Pmltm1.1Ews
Tg(PML-RARA)556Kog/0
FVB.Cg-Pmltm1.1Ews Tg(PML-RARA)556Kog J:262172 View
acute promyelocytic leukemia Tg(CTSG-ZBTB16/RARA)#Ppp/0
Zbtb16tm1Ppp/Zbtb16tm1Ppp
involves: 129S1/Sv J:65878 View
transient myeloproliferative syndrome Gata1tm1Mym/Gata1tm1Mym
Tg(Gata1*)#Mym/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2J J:158252 View
transient myeloproliferative syndrome Gata1tm1Mym/Y
Tg(Gata1*)#Mym/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2J J:158252 View
Transgenes and
Other Mutations
     acute leukemia Tg(Ly6a-SET/NUP214)2969Gcg/0 involves: FVB/NJ J:142938 View
acute lymphoblastic leukemia Tg(Igh-HMGA2)#Cro/0 FVB/N-Tg(Igh-HMGA2)#Cro J:233225 View
acute myeloid leukemia Tg(CMV-SALL4_iB)#Chai/? Not Specified J:115037 View
acute myeloid leukemia Tg(Vav1-ERG)#Jpim/0 involves: C57BL/6 J:203438 View
acute promyelocytic leukemia Tg(CTSG-NUMA1/RARA)#Skr/0 involves: C57BL/6 J:88103 View
acute promyelocytic leukemia Tg(PML-RARA)556Kog/? involves: FVB/N J:39327 View
Burkitt lymphoma Tg(IGL-MYC)3Hm/0 C57BL/6N-Tg(IGL-MYC)3Hm/Nci J:65245 View
chronic lymphocytic leukemia Del(14Trim13-Dleu2)4Rdf/Del(14Trim13-Dleu2)4Rdf involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6 J:156946 View
chronic lymphocytic leukemia Del(14Trim13-Rnaseh2b)6Rdf/+
Cd19tm1(cre)Cgn/Cd19+
involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6 J:179879 View
chronic lymphocytic leukemia Is(14)1Rdf Is(14)2Rdf/Del(14Trim13-Dleu2)4Rdf
Cd19tm1(cre)Cgn/Cd19+
involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6 J:156946 View
chronic lymphocytic leukemia Is(14)1Rdf Is(14)5Rdf/Del(14Trim13-Rnaseh2b)6Rdf
Cd19tm1(cre)Cgn/Cd19+
involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6 J:179879 View
chronic lymphocytic leukemia Mirc30em1Hhzg/Mirc30em1Hhzg
Tg(Vav1-cre)#Cgp/0
involves: 129S4/SvJae * C57BL/6 * C57BL/6NRj J:320883 View
chronic lymphocytic leukemia Mirc30tm1.2Rdf/Mirc30tm1.2Rdf involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6 J:156946 View
chronic lymphocytic leukemia Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0 FVB/N-Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro J:162077 View
chronic lymphocytic leukemia Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0
Tg(Igh-V186.2-TCL1A)3Cro/0
involves: C3H * C57BL/6 * FVB/N J:162077 View
chronic lymphocytic leukemia Tg(Igh-ROR1)1Kip/0 C57BL/6-Tg(Igh-ROR1)1Kip J:206368 View
chronic lymphocytic leukemia Tg(Igh-ROR1)1Kip/0
Tg(Igh-V186.2-TCL1A)3Cro/0
B6.Cg-Tg(Igh-ROR1)1Kip Tg(Igh-V186.2-TCL1A)3Cro J:206368 View
chronic lymphocytic leukemia Tg(Igh-TCL1A)1Ypek/0 FVB/N-Tg(Igh-TCL1A)1Ypek J:160184 View
chronic lymphocytic leukemia Tg(Igh-V186.2-TCL1A)3Cro/0 B6.Cg-Tg(Igh-V186.2-TCL1A)3Cro J:206368 View
chronic lymphocytic leukemia Tg(Igh-V186.2-TCL1A)3Cro/0 involves: C3H * C57BL/6 J:76574 View
chronic lymphocytic leukemia Tg(Lck-TNFSF13)3919Mhah/0 B6.Cg-Tg(Lck-TNFSF13)3919Mhah J:94628 View
chronic myeloid leukemia Gt(ROSA)26Sortm4(CAG-hsb5)Nki/Gt(ROSA)26Sor+
Tg(Mx1-cre)1Cgn/0
Tg(Tal1-tTA)19Dgt/0
Tg(tetO-BCR/ABL1)2Dgt/0
TgTn(pb-sb-GrOnc)#aGsva/0
involves: 129P2/OlaHsd * C57BL/6 * CBA/J * DBA/2 * FVB/N J:227558 View
chronic myeloid leukemia Tg(Ly6a-BCR/ABL1)IS1AIsg/0 involves: C57BL/6J * CBA J:144382 View
chronic myeloid leukemia Tg(Ly6a-BCR/ABL1)IS1BIsg/0 involves: C57BL/6J * CBA J:144382 View
chronic myeloid leukemia Tg(Ly6a-TK,-BCR/ABL1)IS9AIsg/0 involves: C57BL/6J * CBA J:144382 View
chronic myeloid leukemia Tg(tetO-BCR/ABL1)2Dgt/0
Tg(Tal1-tTA)19Dgt/0
involves: C57BL/6 * DBA/2 * FVB/N J:96511 View
essential thrombocythemia Tg(JAK2*V617F)FF1Rsko/0
Commd10Tg(Vav1-icre)A2Kio/Commd10+
involves: C57BL/6 * C57BL/10 * CBA/Ca J:134364 View
essential thrombocythemia Tg(Vav1-JAK2*V617F)AZjz/0 involves: C57BL/6 * DBA/2 J:135993 View
extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue Tg(Ly6e-MALT1)#Isg/0 involves: C57BL/6 * CBA J:185590 View
follicular lymphoma Tg(Vav-BCL2)69Jad/0 involves: C57BL/6J J:88565 View
leukemia Tg(Vav1-STAT5B*N642H)726Biat/0 C57BL/6NCrl-Tg(Vav1-STAT5B*N642H)726Biat J:257519 View
lymphoma Tg(Vav1-STAT5B*N642H)726Biat/0 C57BL/6NCrl-Tg(Vav1-STAT5B*N642H)726Biat J:257519 View
multiple myeloma Tg(Cd4-NPM/ALK)N1Ingh/0 either: (involves: BALB/c * Swiss Webster) or (involves: C57BL/6 * Swiss Webster) J:82127 View
multiple myeloma Tg(Igkv3-5*-MYC)24Plbe/0 C57BL/6J-Tg(Igkv3-5*-MYC)DLoxP4Plbe/PlbeMmmh J:131912 View
myelodysplastic syndrome Tg(CMV-SALL4_iB)#Chai/? Not Specified J:115037 View
myelodysplastic syndrome Tg(Vav1-NUP98/HOXD13)C1Apla/0 FVB/N-Tg(Vav1-NUP98/HOXD13)C1Apla J:107446 View
myelodysplastic syndrome Tg(Vav1-NUP98/HOXD13)G2Apla/0 C57BL/6-Tg(Vav1-NUP98/HOXD13)G2Apla J:107446 View
myelofibrosis Tg(Vav1-JAK2*V617F)AZjz/0 involves: C57BL/6 * DBA/2 J:135993 View
non-Hodgkin lymphoma Tg(EmuSR-HDAC9)1468Kpet/0 involves: C57BL/6 * CBA J:237420 View
non-Hodgkin lymphoma Tg(EmuSR-tTa)83Bop/Tg(EmuSR-tTa)83Bop
Tg(tetO-NPM1/ALK,-luc)2Gde/0
involves: FVB/N J:160236 View
non-Hodgkin lymphoma Tg(EmuSR-tTa)83Bop/Tg(EmuSR-tTa)83Bop
Tg(tetO-TPM3/ALK,-luc)2Gde/0
involves: FVB/N J:160236 View
plasmacytoma Tg(H2-L-IL6)46Kish/Tg(H2-L-IL6)46Kish C.B6-Tg(H2-L-IL6)46Kish J:74377 View
polycythemia vera Tg(JAK2*V617F)FF1Rsko/0
Tg(Mx1-cre)1Cgn/0
involves: C57BL/6 * CBA J:134364 View
polycythemia vera Tg(Vav1-JAK2*V617F)AZjz/0 involves: C57BL/6 * DBA/2 J:135993 View
Additional
Complex
Models
     acute leukemia Cd3etm1Mal/Cd3etm1Mal
Tg(Tcrb-TCF3/PBX1)23Gusa/0
involves: C3H * C57BL/6 * C57BL/6J J:95693 View
acute lymphoblastic leukemia Etv6tm1.1(RUNX1,hsb5)Lvdw/Etv6+
TgTn(sb-T2/Onc)76Dla/0
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * FVB/N J:174866 View
acute lymphoblastic leukemia Tcf3tm1(PBX1)Mlc/Tcf3+
Cd19tm1(cre)Cgn/Cd19+
involves: 129P2/OlaHsd * C57BL/6 J:226241 View
acute lymphoblastic leukemia Tcf3tm1(PBX1)Mlc/Tcf3+
Cd79atm1(cre)Reth/Cd79a+
involves: BALB/c * C57BL/6 J:226241 View
acute lymphoblastic leukemia Tcf3tm1(PBX1)Mlc/Tcf3+
Tg(Mx1-cre)1Cgn/0
involves: C57BL/6 * C57BL/6J * CBA/J J:226241 View
acute lymphoblastic leukemia Tg(Lck-LMO1)11Sjk/0
Tg(STIL-TAL1)A5(3)Alpa/0
involves: C3H * C3H/HeRos * C57BL/6 * C57BL/10Ros J:40868 View
acute lymphoblastic leukemia Zfp36l1tm1.1Tnr/Zfp36l1tm1.1Tnr
Zfp36l2tm1.1Tnr/Zfp36l2tm1.1Tnr
Tg(CD2-icre)4Kio/0
involves: C57BL/6 * C57BL/10 * CBA/Ca * SJL J:162388 View
acute myeloid leukemia Ctsgtm2.1(PML/RARA)Ley/Ctsg+ involves: 129X1/SvJ * C57BL/6 J:84230, J:86458 View
acute myeloid leukemia Nr4a1tm1Jmi/Nr4a1tm1Jmi
Nr4a3tm1Omc/Nr4a3tm1Omc
involves: 129S/SvEv * 129S2/SvPas * C57BL/6 J:121903 View
acute promyelocytic leukemia Tg(CTSG-RARA/ZBTB16)#Ppp/0
Tg(CTSG-ZBTB16/RARA)#Ppp/0
Not Specified J:65878 View
acute promyelocytic leukemia Tg(CTSG-RARA/ZBTB16)#Sjch/0
Tg(CTSG-ZBTB16/RARA)#Sjch/0
Not Specified J:194312 View
B-cell lymphoma Cd19tm1(cre)Cgn/Cd19+
Inpp5dtm1Rav/Inpp5dtm1Rav
Ptentm1Hwu/Ptentm1Hwu
involves: 129P2/OlaHsd * 129S4/SvJae J:166155 View
chronic lymphocytic leukemia Ightm1.1(Tag)Rwhe/Igh+ involves: 129P2/OlaHsd * C57BL/6 J:150315 View
chronic lymphocytic leukemia Ightm2.1(Tag)Rwhe/Igh+ involves: 129P2/OlaHsd * C57BL/6 J:150315 View
chronic lymphocytic leukemia Ighatm1(Myc)Janz/Igha+
Tg(Tnfsf13b)1Fma/0
involves: 129S1/Sv * C57BL/6 * DBA/2J J:166158 View
chronic lymphocytic leukemia Is(14)1Rdf/Is(14)1Rdf
Is(14)5Rdf/Is(14)5Rdf
Cd19tm1(cre)Cgn/Cd19+
involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6 J:179879 View
chronic lymphocytic leukemia Tg(BCL2/IGH)#Jcre/0
Tg(H2-K/Igh-Traf2*)#Ywc/0
involves: BALB/c * C57BL/6 * CBA/J * FVB/N * SJL/J * SWR/J J:94116 View
chronic myeloid leukemia Dok1tm1Ppp/Dok1+
Tg(Tec-BCR/ABL1)5Hhi/0
involves: 129S1/Sv J:95334 View
chronic myeloid leukemia Dok1tm1Ppp/Dok1tm1Ppp
Dok2tm1Ppp/Dok2tm1Ppp
129S1/Sv-Dok1tm1Ppp Dok2tm1Ppp J:95334 View
chronic myeloid leukemia Dok1tm1Ppp/Dok1tm1Ppp
Tg(Tec-BCR/ABL1)5Hhi/0
involves: 129S1/Sv J:95334 View
chronic myeloid leukemia Dok1tm1Yyam/Dok1tm1Yyam
Dok2tm1Yyam/Dok2tm1Yyam
B6.129-Dok1tm1Yyam Dok2tm1Yyam J:95335 View
chronic myeloid leukemia Dok1tm1Yyam/Dok1tm1Yyam
Dok2tm1Yyam/Dok2tm1Yyam
Tg(Tec-BCR/ABL1)5Hhi/0
involves: C57BL/6 J:95335 View
chronic myeloid leukemia Dok1tm1Yyam/Dok1tm1Yyam
Tg(Tec-BCR/ABL1)5Hhi/0
involves: C57BL/6 J:95335 View
chronic myeloid leukemia Dok2tm1Ppp/Dok2+
Tg(Tec-BCR/ABL1)5Hhi/0
involves: 129S1/Sv J:95334 View
chronic myeloid leukemia Dok2tm1Ppp/Dok2tm1Ppp
Tg(Tec-BCR/ABL1)5Hhi/0
involves: 129S1/Sv J:95334 View
chronic myeloid leukemia Dok2tm1Yyam/Dok2tm1Yyam
Tg(Tec-BCR/ABL1)5Hhi/0
involves: C57BL/6 J:95335 View
diffuse large B-cell lymphoma Cd19tm1(cre)Cgn/Cd19+
Gt(ROSA)26Sortm2(CARD11*L225LI)Jrld/Gt(ROSA)26Sor+
involves: 129P2/OlaHsd J:228288 View
histiocytic and dendritic cell cancer Cdk5rap2an/Cdk5rap2an
Tyrp1B-lt/Tyrp1B-lt
WBB6F1 J:160533 View
leukemia Kmt2atm1.1(Sh3gl1)Lcc/Kmt2a+
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 J:205605 View
lymphoid leukemia Col1a1tm4(tetO-GFP/RNAi:Apc)Slowe/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 J:171191 View
lymphoma Epm2aTg(TcraK,TcrbK)TG-BFlv/Epm2a+ involves: C57BL/6 * C57BL/10 * C57BR/cd * CBA/J J:112696 View
lymphoma Espl1Gt(XL058)Byg/Espl1+
Trp53tm1Tyj/Trp53tm1Tyj
B6.129-Trp53tm1Tyj Espl1Gt(XL058)Byg J:174926 View
multiple myeloma Ightm1(Myc)Janz/Igh+
Tg(Emu-FGFR3)A5Wmk/0
involves: 129X1/SvJ * C57BL/6 * FVB/N J:160845 View
multiple myeloma Ightm1(Myc)Janz/Igh+
Tg(Emu-FGFR3)D3Wmk/0
involves: 129X1/SvJ * C57BL/6 * FVB/N J:160845 View
myeloproliferative neoplasm Col1a1tm2(tetO-GFP/RNAi:Smc1a)Iaai/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 J:229031 View
non-Hodgkin lymphoma Gt(ROSA)26Sortm4(Ikbkb)Rsky/Gt(ROSA)26Sor+
Ighg1tm1(cre)Cgn/Ighg1+
Prdm1tm2Masu/Prdm1tm2Masu
involves: 129P2/OlaHsd * C57BL/6 J:167612 View
non-Hodgkin lymphoma Ighmtm1(Bcl6)Rdf/? involves: 129/Sv * C57BL/6 J:98937 View


       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      acute myeloid leukemia Krastm4Tyj/Kras+
Tg(Mx1-cre)1Cgn/0
involves: 129S4/SvJae * C57BL/6 * CBA J:87429 View
acute myeloid leukemia Npm1tm1Hft/Npm1+ involves: 129 J:194999 View
essential thrombocythemia Jak2tm1.1Jlvl/Jak2tm1.1Jlvl involves: 129S2/SvPas * C57BL/6 J:163497 View