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All mouse models of corneal dystrophy with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
congenital hereditary endothelial dystrophy of cornea | Slc4a11tm1.1Jrcy/Slc4a11tm1.1Jrcy | involves: C57BL/6 | J:214272 | View | ||||
congenital stromal corneal dystrophy |
Tg(CAG-cat,-Dcn*)#Debi/0 Tg(Kera-cre)KC4.3Wwk/0 |
involves: FVB/N | J:177392 | View | ||||
corneal dystrophy | Tgfbiem1Yaou/Tgfbiem1Yaou | involves: C57BL/6NCr | J:285437 | View | ||||
Fuchs' endothelial dystrophy | Col8a2tm1.1Asj/Col8a2tm1.1Asj | involves: 129S6/SvEvTac | J:214908 | View | ||||
Fuchs' endothelial dystrophy | Col8a2tm1.1Asj/Col8a2tm1.1Asj | involves: 129S6/SvEvTac * C57BL/6 * CBA | J:179022 | View | ||||
Fuchs' endothelial dystrophy | Col8a2tm2.1Asj/Col8a2tm2.1Asj | involves: 129S6/SvEvTac * C57BL/6 * CBA | J:21908 | View | ||||
Schnyder corneal dystrophy | Ubiad1em1Wwk/Ubiad1+ | C57BL/6N-Ubiad1em1Wwk | J:268574 | View | ||||
Schnyder corneal dystrophy | Ubiad1em1Wwk/Ubiad1em1Wwk | C57BL/6N-Ubiad1em1Wwk | J:268574 | View | ||||
Additional Complex Models | Meesmann corneal dystrophy | Krt12tm1.1(KRT12*L132P)Arte/Krt12tm1.1(KRT12*L132P)Arte | involves: C57BL/6 | J:229462 | View |
No similarity to the expected human disease phenotype was found.
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
NOT Models | Fuchs' endothelial dystrophy |
Col8a1tm1Bjro/Col8a1tm1Bjro Col8a2tm1Bjro/Col8a2tm1Bjro |
B6.129S4-Col8a2tm1Bjro Col8a1tm1Bjro | J:100136 | View | |||
Fuchs' endothelial dystrophy | Col8a2Aca23/Col8a2+ | C57BL/6J-Col8a2Aca23 | J:158259 | View | ||||
Fuchs' endothelial dystrophy | Col8a2Aca23/Col8a2Aca23 | C57BL/6J-Col8a2Aca23 | J:158259 | View |