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All mouse models of pancreas disease with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | Mahvash Disease | Gcgrem2Smoc/Gcgrem2Smoc | C57BL/6J-Gcgrem2Smoc | J:300368 | View | |||
| | annular pancreas | Gdf1tm1Sjl/Gdf1tm1Sjl | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:60755 | View | |||
| annular pancreas | Ihhtm1Amc/Ihhtm1Amc | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J | J:62158 | View | ||||
| pancreatic carcinoma |
Brca2tm1Brn/Brca2tm1Cam Krastm4Tyj/Kras+ Trp53tm3Tyj/Trp53+ Tg(Pdx1-cre)6Tuv/0 |
involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB/N | J:166678 | View | ||||
| pancreatic carcinoma |
Cdkn2atm4Rdp/Cdkn2atm4Rdp Krastm4Tyj/Kras+ Tg(Pdx1-cre)89.1Dam/0 |
involves: 129S4/SvJae * C57BL/6 * CBA | J:187012 | View | ||||
| pancreatic carcinoma |
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+ Ptf1atm1.1(cre)Cvw/Ptf1a+ Tg(tetO-Kras*G12D)#Rdp/0 Trp53tm1Brn/Trp53+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N | J:186194 | View | ||||
| pancreatic carcinoma |
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+ Ptf1atm1.1(cre)Cvw/Ptf1a+ Tg(tetO-Kras*G12D)#Rdp/0 Trp53tm1Brn/Trp53tm1Brn |
involves: 129P2/OlaHsd * 129S/Sv * 129X1/SvJ * C57BL/6 * FVB/N | J:186194 | View | ||||
| pancreatic carcinoma |
Krastm1Bbd/Kras+ Trp53tm1Brd/Trp53+ Tg(Cela1-tTA)#Eps/? Tg(tetO-cre)3Jig/? |
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * FVB/N | J:119988 | View | ||||
| pancreatic carcinoma |
Krastm1Bbd/Krastm1Bbd Tg(Cela1-tTA)#Eps/? Tg(tetO-cre)3Jig/? |
involves: 129S1/Sv * 129X1/SvJ * FVB/N | J:119988 | View | ||||
| pancreatic carcinoma |
Krastm4Tyj/Kras+ Ptentm1Hwu/Pten+ Tg(Pdx1-cre)89.1Dam/0 |
involves: 129S4/SvJae * BALB/c * C57BL/6 | J:164210 | View | ||||
| pancreatic carcinoma |
Krastm4Tyj/Kras+ Ptentm1Hwu/Ptentm1Hwu Tg(Pdx1-cre)89.1Dam/0 |
involves: 129S4/SvJae * BALB/c * C57BL/6 * CBA | J:164210 | View | ||||
| pancreatic carcinoma |
Krastm4Tyj/Kras+ Ptf1atm1.1(cre)Cvw/Ptf1a+ |
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ | J:87973 | View | ||||
| pancreatic carcinoma |
Krastm4Tyj/Kras+ Ptf1atm1.1(cre)Cvw/Ptf1a+ Tg(MUC1)79.24Gend/0 |
B6.Cg-Krastm4Tyj Ptf1atm1.1(cre)Cvw Tg(MUC1)79.24Gend | J:234412 | View | ||||
| pancreatic carcinoma |
Krastm4Tyj/Kras+ Tg(CAG-Bgeo,-tsA58T)T26Ichi/0 Tg(Pdx1-cre)6Tuv/0 |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB/N | J:214846 | View | ||||
| pancreatic carcinoma |
Krastm4Tyj/Kras+ Tg(Pdx1-cre)6Tuv/0 Trp53tm1Gev/Trp53tm1Gev |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB/N | J:220300 | View | ||||
| pancreatic carcinoma |
Krastm4Tyj/Kras+ Tg(Pdx1-cre)6Tuv/? |
involves: 129S4/SvJae * FVB/N | J:87973 | View | ||||
| pancreatic carcinoma | Tg(Ela1-Myc)158Bri/0 | involves: C57BL/6 * SJL | J:76992 | View | ||||
| pancreatic carcinoma | Tg(Ela1-Myc)159Bri/0 | involves: C57BL/6 * SJL | J:76992 | View | ||||
| pancreatic carcinoma | Tg(Ela1-Myc)160Bri/0 | involves: C57BL/6 * SJL | J:76992 | View | ||||
| pancreatitis | Cpa1tm1.1Satom/Cpa1tm1.1Satom | involves: C57BL/6NCrl * FVB/N | J:300042 | View | ||||
| pancreatitis | Prss3btm1.1Satom/Prss3b+ | B6(FVB)-Prss3btm1.1Satom | J:267764 | View | ||||
| Transgenes and Other Mutations | insulinoma | Tg(RIP1-Tag)2Dh/0 | involves: C57BL/6J * DBA/2J | J:205389 | View | |||
| pancreatic carcinoma |
Bcl2l1tm1.1Mam/Bcl2l1tm1.1Mam Tg(Ins2-cre)25Mgn/0 Tg(RIP1-Tag)2Dh/0 |
involves: 129S6/SvEvTac * C57BL/6 * DBA | J:146436 | View | ||||
| pancreatic carcinoma |
Bcl2l1tm1.1Mam/Bcl2l1tm1.1Mam Tg(RIP1-Tag)2Dh/0 |
involves: 129S6/SvEvTac * C57BL/6 * DBA | J:146436 | View | ||||
| pancreatic carcinoma |
Tg(CAG-Bgeo,-tTA,-EGFP)2A11Kuw/0 Tg(Pdx1-cre)6Tuv/0 Tg(tetO-MYC)36Bop/0 |
involves: 129P2/OlaHsd * FVB/N | J:197052 | View | ||||
| pancreatic carcinoma | Tg(Cela1-luc,Cela1-TAg)#Nzh/0 | involves: FVB/N | J:207960 | View | ||||
| pancreatic carcinoma | Tg(Ela1-TAg)18Bri/0 | involves: C57BL/6 * SJL | J:76995 | View | ||||
| pancreatic carcinoma | Tg(Ela1-TAg)19Bri/0 | involves: C57BL/6 * SJL | J:76995 | View | ||||
| pancreatic carcinoma | Tg(Ins2-Tag*,-flpe)#Gne/0 | involves: C57BL/6J | J:187012 | View | ||||
| pancreatic carcinoma | Tg(Ins2-Tag*,-flpe)#Gne/0 | Not Specified | J:188693 | View | ||||
| pancreatic carcinoma | Tg(RIP1-Tag)2Dh/0 | involves: C57BL/6J * DBA/2J | J:50695 | View | ||||
| pancreatic carcinoma | Tg(RIR-Tag)87Dh/0 | involves: C57BL/6J * DBA/2J | J:50695 | View | ||||
| Additional Complex Models | annular pancreas | Dp(16Lipi-Zbtb21)1Yey/0 | involves: 129S7/SvEvBrd | J:121790 | View | |||
| pancreatic carcinoma |
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+ Ptf1atm1.1(cre)Cvw/Ptf1a+ Tg(tetO-Kras2)12Hev/0 Trp53tm1Tyj/Trp53+ |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N | J:184378 | View | ||||
| pancreatic carcinoma |
Rb1tm2Brn/Rb1tm2Brn Trp53tm1Brn/Trp53tm1Brn Tg(Ren-cre)#Kwg/0 |
involves: 129 * 129P2/OlaHsd | J:216559 | View | ||||
| pancreatic carcinoma |
Tg(Ela1-Tgfa)150Bri/0 Trp53tm1Tyj/Trp53+ |
involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL | J:67389 | View | ||||
| pancreatic carcinoma |
Tg(Ela1-Tgfa)150Bri/0 Trp53tm1Tyj/Trp53tm1Tyj |
involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL | J:67389 | View | ||||
| pancreatic carcinoma |
Tg(Ela-KRAS*G12D)9Eps/0 Tg(Mt1-TGFBR2*)AM3Epb/0 |
involves: C57BL/6 * FVB | J:231759 | View | ||||
| pancreatic ductal adenocarcinoma |
Cdkn2atm2.1Rdp/Cdkn2a+ Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53tm1Brn Tg(Pdx1-cre)89.1Dam/0 |
involves: 129 * C57BL/6 * CBA * FVB/N | J:108298 | View | ||||
| pancreatic ductal adenocarcinoma |
Cdkn2atm2.1Rdp/Cdkn2atm2.1Rdp Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53+ Tg(Pdx1-cre)89.1Dam/0 |
involves: 129 * C57BL/6 * CBA * FVB/N | J:108298 | View | ||||
| pancreatic ductal adenocarcinoma |
Cdkn2atm2.1Rdp/Cdkn2atm2.1Rdp Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53tm1Brn Tg(Pdx1-cre)89.1Dam/0 |
involves: 129 * C57BL/6 * CBA * FVB/N | J:108298 | View | ||||
| pancreatic ductal adenocarcinoma |
Cdkn2atm4Rdp/Cdkn2atm4Rdp Krastm4Tyj/Kras+ Tg(Pdx1-cre)89.1Dam/0 |
involves: 129S4/SvJae * C57BL/6 * CBA * FVB/N | J:87196, J:108298 | View | ||||
| pancreatic ductal adenocarcinoma |
Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ Hmga2tm1.1Mmw/Hmga2+ Krastm4Tyj/Kras+ Tg(Pdx1-cre)6Tuv/0 Trp53tm2Tyj/Trp53+ |
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6NCrl * FVB/N | J:245611 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm1.1Khai/Kras+ Tg(Pdx1-cre)6Tuv/0 Trp53tm3.1Tyj/Trp53+ |
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * FVB/N | J:276349 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm4Tyj/Kras+ Tg(Pdx1-cre)6Tuv/0 Trp53tm3.1Tyj/Trp53+ |
involves: 129S4/SvJae * C57BL/6 * FVB/N | J:276349 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm4Tyj/Kras+ Tg(Pdx1-cre)6Tuv/0 Usp9xtm1Tuv/Usp9x+ |
involves: 129S4/SvJae * FVB/N | J:186717 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm4Tyj/Kras+ Tg(Pdx1-cre)6Tuv/0 Usp9xtm1Tuv/Y |
involves: 129S4/SvJae * FVB/N | J:186717 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53tm1Brn Tg(Pdx1-cre)89.1Dam/0 |
involves: 129 * C57BL/6 * CBA * FVB/N | J:108298 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm4Tyj/Kras+ Trp53tm2Tyj/Trp53+ Tg(Pdx1-cre)6Tuv/0 |
involves: 129S4/SvJae * C57BL/6 * FVB/N | J:98936 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm5Tyj/Kras+ Pdx1tm1.1(flpo)Most/Pdx1+ Trp53tm1.1Dgk/Trp53+ |
involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * Black Swiss * C57BL/6 | J:248550 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm5Tyj/Kras+ Pdx1tm1.1(flpo)Most/Pdx1+ Trp53tm1.1Dgk/Trp53tm1.1Dgk |
involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * Black Swiss * C57BL/6 | J:248550 | View | ||||
| pancreatic mucinous cystadenoma |
Apctm2Rak/Apc+ Trp53tm1Brn/Trp53tm1Brn Tg(Pdx1-cre)6Tuv/0 |
involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N * SJL | J:234310 | View | ||||
| pancreatitis |
Foxp3tm2.1(EGFP/cre)Shori/Y Pdcd1tm1Hon/Pdcd1tm1Hon |
involves: 129 * 129S2/SvPas * C57BL/6 | J:234397 | View | ||||