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All mouse models of adenocarcinoma with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | intrahepatic cholangiocarcinoma |
Krastm4Tyj/Kras+ Ptentm2Mak/Ptentm2Mak Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA | J:254370 | View | |||
| intrahepatic cholangiocarcinoma |
Krastm4Tyj/Kras+ Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129S4/SvJae * C57BL/6 * DBA | J:184949 | View | ||||
| intrahepatic cholangiocarcinoma |
Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53+ Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA | J:184949 | View | ||||
| intrahepatic cholangiocarcinoma |
Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53tm1Brn Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA | J:184949 | View | ||||
| papillary thyroid carcinoma |
Braftm1Cpri/Braftm1Cpri Tg(TPO-cre)1Shk/0 |
involves: 129P2/OlaHsd * FVB/NCr | J:168249 | View | ||||
| papillary thyroid carcinoma |
Braftm1Mmcm/Braf+ Tg(Tg-cre/ERT2)#Mmcm/0 |
involves: 129P2/OlaHsd | J:172205 | View | ||||
| | follicular thyroid carcinoma |
Prkar1atm1.2Lsk/Prkar1atm1.2Lsk Ptentm1.1Mwst/Ptentm1.1Mwst Tg(TPO-cre)1Shk/0 |
involves: 129S1/Sv * 129X1/SvJ * FVB/NCr | J:241066 | View | |||
| follicular thyroid carcinoma |
Prkar1atm1.2Lsk/Prkar1atm1.2Lsk Tg(TPO-cre)1Shk/0 |
involves: 129S1/Sv * 129X1/SvJ * FVB/NCr | J:241066 | View | ||||
| follicular thyroid carcinoma |
Ptentm1Hwu/Pten+ Tg(Nkx2-1-cre)2Sand/0 |
B6.Cg-Ptentm1Hwu Tg(Nkx2-1-cre)2Sand | J:197590 | View | ||||
| follicular thyroid carcinoma |
Ptentm2.1Ppp/Ptentm2.1Ppp Tg(TPO-cre)1Shk/0 |
129S1.Cg-Ptentm2.1Ppp Tg(TPO-cre)1Shk | J:165293 | View | ||||
| follicular thyroid carcinoma | Thrbtm1.1Syc/Thrbtm1.1Syc | involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6 * C57BL/6J | J:92629 | View | ||||
| follicular thyroid carcinoma | Thrbtm1Df/Thrbtm1.1Syc | involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6 * C57BL/6J | J:92629 | View | ||||
| Transgenes and Other Mutations | follicular thyroid carcinoma | Tg(TG-NRAS*Q61K)#Msnt/0 | Not Specified | J:210016 | View | |||
| lung adenocarcinoma |
Tg(Scgb1a1-rtTA)1Jaw/0 Tg(tetO-Kras2)12Hev/0 |
involves: 129 * C57BL/6 * FVB/N | J:73468 | View | ||||
| lung adenocarcinoma | Tg(SFTPC-env)1Yhch/0 | FVB/N-Tg(SFTPC-env)1Yhch | J:247986 | View | ||||
| papillary thyroid carcinoma |
Tg(tetO-BRAF*V600E)26Jaf/0 Tg(TG-rtTA)30Jaf/0 |
involves: FVB/N | J:184420 | View | ||||
| papillary thyroid carcinoma | Tg(TG-BRAF*V600E)2Jaf/0 | FVB/N-Tg(TG-BRAF*V600E)2Jaf | J:98550, J:195921 | View | ||||
| papillary thyroid carcinoma | Tg(TG-RET/CCDC6)42Cled/0 | involves: FVB/N | J:93679, J:55883 | View | ||||
| papillary thyroid carcinoma | Tg(TG-RET/NCOA4)3209Rstn/0 | involves: C57BL/6 | J:51366 | View | ||||
| papillary thyroid carcinoma | Tg(TG-TPR/NTRK1)5215Rstn/0 | involves: C3H * C57BL/6 | J:67120 | View | ||||
| prostate adenocarcinoma | Tg(Pbsn-Tag)12T10Rjm/0 | involves: CD-1 | J:68483 | View | ||||
| Additional Complex Models | pancreatic ductal adenocarcinoma |
Cdkn2atm2.1Rdp/Cdkn2a+ Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53tm1Brn Tg(Pdx1-cre)89.1Dam/0 |
involves: 129 * C57BL/6 * CBA * FVB/N | J:108298 | View | |||
| pancreatic ductal adenocarcinoma |
Cdkn2atm2.1Rdp/Cdkn2atm2.1Rdp Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53+ Tg(Pdx1-cre)89.1Dam/0 |
involves: 129 * C57BL/6 * CBA * FVB/N | J:108298 | View | ||||
| pancreatic ductal adenocarcinoma |
Cdkn2atm2.1Rdp/Cdkn2atm2.1Rdp Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53tm1Brn Tg(Pdx1-cre)89.1Dam/0 |
involves: 129 * C57BL/6 * CBA * FVB/N | J:108298 | View | ||||
| pancreatic ductal adenocarcinoma |
Cdkn2atm4Rdp/Cdkn2atm4Rdp Krastm4Tyj/Kras+ Tg(Pdx1-cre)89.1Dam/0 |
involves: 129S4/SvJae * C57BL/6 * CBA * FVB/N | J:87196, J:108298 | View | ||||
| pancreatic ductal adenocarcinoma |
Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ Hmga2tm1.1Mmw/Hmga2+ Krastm4Tyj/Kras+ Tg(Pdx1-cre)6Tuv/0 Trp53tm2Tyj/Trp53+ |
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6NCrl * FVB/N | J:245611 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm1.1Khai/Kras+ Tg(Pdx1-cre)6Tuv/0 Trp53tm3.1Tyj/Trp53+ |
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * FVB/N | J:276349 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm4Tyj/Kras+ Tg(Pdx1-cre)6Tuv/0 Trp53tm3.1Tyj/Trp53+ |
involves: 129S4/SvJae * C57BL/6 * FVB/N | J:276349 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm4Tyj/Kras+ Tg(Pdx1-cre)6Tuv/0 Usp9xtm1Tuv/Usp9x+ |
involves: 129S4/SvJae * FVB/N | J:186717 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm4Tyj/Kras+ Tg(Pdx1-cre)6Tuv/0 Usp9xtm1Tuv/Y |
involves: 129S4/SvJae * FVB/N | J:186717 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53tm1Brn Tg(Pdx1-cre)89.1Dam/0 |
involves: 129 * C57BL/6 * CBA * FVB/N | J:108298 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm4Tyj/Kras+ Trp53tm2Tyj/Trp53+ Tg(Pdx1-cre)6Tuv/0 |
involves: 129S4/SvJae * C57BL/6 * FVB/N | J:98936 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm5Tyj/Kras+ Pdx1tm1.1(flpo)Most/Pdx1+ Trp53tm1.1Dgk/Trp53+ |
involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * Black Swiss * C57BL/6 | J:248550 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm5Tyj/Kras+ Pdx1tm1.1(flpo)Most/Pdx1+ Trp53tm1.1Dgk/Trp53tm1.1Dgk |
involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * Black Swiss * C57BL/6 | J:248550 | View | ||||
| prostate adenocarcinoma |
Gt(ROSA)26Sortm1(CAG-AR)Zsu/Gt(ROSA)26Sor+ Tg(Osr1-cre)4Mrt/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N | J:234601 | View | ||||
| prostate adenocarcinoma |
Gt(ROSA)26Sortm1(CAG-AR)Zsu/Gt(ROSA)26Sortm1(CAG-AR)Zsu Tg(Osr1-cre)4Mrt/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N | J:234601 | View | ||||