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All mouse models of carcinoma with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | basal cell carcinoma |
Ptch1tm1Bjw/Ptch1tm1Bjw Tg(KRT14-cre)8Brn/0 |
involves: 129T2/SvEms * FVB/N | J:231264 | View | |||
| basal cell carcinoma |
Ptch1tm1Hahn/Ptch1tm1Hahn Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ | J:158915 | View | ||||
| basal cell carcinoma | Ptch1tm1Mps/Ptch1+ | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2J | J:58328 | View | ||||
| hepatocellular carcinoma | Apctm2.1Cip/Apctm2.1Cip | involves: 129P2/OlaHsd * C57BL/6N | J:94721 | View | ||||
| hepatocellular carcinoma | Nr1h4tm1Gonz/Nr1h4tm1Gonz | involves: 129X1/SvJ * C57BL/6 | J:118204, J:170790 | View | ||||
| hepatocellular carcinoma | Nr1h4tm1Gonz/Nr1h4tm1Gonz | involves: 129X1/SvJ * C57BL/6N | J:121075, J:170790 | View | ||||
| intrahepatic cholangiocarcinoma |
Krastm4Tyj/Kras+ Ptentm2Mak/Ptentm2Mak Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA | J:254370 | View | ||||
| intrahepatic cholangiocarcinoma |
Krastm4Tyj/Kras+ Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129S4/SvJae * C57BL/6 * DBA | J:184949 | View | ||||
| intrahepatic cholangiocarcinoma |
Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53+ Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA | J:184949 | View | ||||
| intrahepatic cholangiocarcinoma |
Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53tm1Brn Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA | J:184949 | View | ||||
| papillary thyroid carcinoma |
Braftm1Cpri/Braftm1Cpri Tg(TPO-cre)1Shk/0 |
involves: 129P2/OlaHsd * FVB/NCr | J:168249 | View | ||||
| papillary thyroid carcinoma |
Braftm1Mmcm/Braf+ Tg(Tg-cre/ERT2)#Mmcm/0 |
involves: 129P2/OlaHsd | J:172205 | View | ||||
| | familial medullary thyroid carcinoma | Prlrtm1Cnp/Prlrtm1Cnp | involves: 129/Sv * 129P2/OlaHsd | J:101609 | View | |||
| follicular thyroid carcinoma |
Prkar1atm1.2Lsk/Prkar1atm1.2Lsk Ptentm1.1Mwst/Ptentm1.1Mwst Tg(TPO-cre)1Shk/0 |
involves: 129S1/Sv * 129X1/SvJ * FVB/NCr | J:241066 | View | ||||
| follicular thyroid carcinoma |
Prkar1atm1.2Lsk/Prkar1atm1.2Lsk Tg(TPO-cre)1Shk/0 |
involves: 129S1/Sv * 129X1/SvJ * FVB/NCr | J:241066 | View | ||||
| follicular thyroid carcinoma |
Ptentm1Hwu/Pten+ Tg(Nkx2-1-cre)2Sand/0 |
B6.Cg-Ptentm1Hwu Tg(Nkx2-1-cre)2Sand | J:197590 | View | ||||
| follicular thyroid carcinoma |
Ptentm2.1Ppp/Ptentm2.1Ppp Tg(TPO-cre)1Shk/0 |
129S1.Cg-Ptentm2.1Ppp Tg(TPO-cre)1Shk | J:165293 | View | ||||
| follicular thyroid carcinoma | Thrbtm1.1Syc/Thrbtm1.1Syc | involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6 * C57BL/6J | J:92629 | View | ||||
| follicular thyroid carcinoma | Thrbtm1Df/Thrbtm1.1Syc | involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6 * C57BL/6J | J:92629 | View | ||||
| hepatocellular carcinoma | Abcb4tm1Bor/Abcb4tm1Bor | either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * FVB/N) | J:21232 | View | ||||
| hepatocellular carcinoma | Cdkn1atm1(HBsAg)Xya/Cdkn1a+ | either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * Black Swiss) | J:88078 | View | ||||
| hepatocellular carcinoma | Cdkn1atm1(HBsAg)Xya/Cdkn1atm1(HBsAg)Xya | either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * Black Swiss) | J:88078 | View | ||||
| hepatocellular carcinoma | Cdkn1atm2(HBx)Xya/Cdkn1a+ | either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * Black Swiss) | J:88078 | View | ||||
| hepatocellular carcinoma | Cdkn1atm2(HBx)Xya/Cdkn1atm2(HBx)Xya | either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * Black Swiss) | J:88078 | View | ||||
| hepatocellular carcinoma | Foxm1tm1Rhc/Foxm1tm1Rhc | involves: 129X1/SvJ | J:89472 | View | ||||
| hepatocellular carcinoma | Gnmttm1Ymac/Gnmttm1Ymac | involves: 129 * C57BL/6 | J:146081 | View | ||||
| hepatocellular carcinoma |
Gtf2ird1Tg(Alb1-Myc)166.8Sst/Gtf2ird1+ Tg(Alb-E2F1)8Sst/0 |
involves: C57BL/6 * CBA | J:101128, J:170790 | View | ||||
| hepatocellular carcinoma |
Gtf2ird1Tg(Alb1-Myc)166.8Sst/Gtf2ird1+ Tg(MtTGFA)42Lmb/0 |
involves: C57BL/6 * CBA * CD-1 | J:34434 | View | ||||
| hepatocellular carcinoma | Iqgap2tm1Vs/Iqgap2tm1Vs | involves: 129S4/SvJae | J:205882 | View | ||||
| hepatocellular carcinoma | Krt18tm1Tmm/Krt18tm1Tmm | involves: 129P2/OlaHsd | J:309021 | View | ||||
| hepatocellular carcinoma |
Lect2tm1Ymg/Lect2tm1Ymg Tg(Pklr-Myc)73Ak/0 |
B6.Cg-Lect2tm1Ymg Tg(Pklr-Myc)73Ak | J:184496 | View | ||||
| hepatocellular carcinoma | Mcm9Gt(AW0655)Wtsi/Mcm9Gt(AW0655)Wtsi | involves: 129P2/OlaHsd * C3HeB/FeJ | J:177420 | View | ||||
| hepatocellular carcinoma | Mcm9Gt(AW0655)Wtsi/Mcm9Gt(XG743)Byg | involves: 129P2/OlaHsd * C3HeB/FeJ | J:177420 | View | ||||
| hepatocellular carcinoma | Mcm9Gt(XG743)Byg/Mcm9Gt(XG743)Byg | involves: 129P2/OlaHsd * C3HeB/FeJ | J:177420 | View | ||||
| hepatocellular carcinoma |
Nfe2l1tm1Jefc/Nfe2l1tm1Ywk Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129X1/SvJ * C57BL/6J | J:97188 | View | ||||
| hepatocellular carcinoma |
Ptentm1Hwu/Ptentm1Hwu Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129S4/SvJae * C57BL/6 * DBA | J:218587 | View | ||||
| hepatocellular carcinoma |
Ptentm2Mak/Ptentm2Mak Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * DBA | J:90905 | View | ||||
| hepatocellular carcinoma |
Ptentm2Mak/Ptentm2Mak Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129P2/OlaHsd * C57BL/6 * DBA | J:138099 | View | ||||
| hepatocellular carcinoma |
Sav1tm2.1Dlim/Sav1tm2.1Dlim Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: C57BL/6 * DBA | J:238319 | View | ||||
| hepatocellular carcinoma |
Tcra-Jtm1Tgi/Tcra-Jtm1Tgi Tg(Pklr-Myc)73Ak/0 |
B6.Cg-Tcra-Jtm1Tgi Tg(Pklr-Myc)73Ak | J:184496 | View | ||||
| hepatocellular carcinoma |
Tg(Alb1-Myc)#Sst/0 Tg(MtTGFA)Lmb/0 |
involves: C57BL/6 * CBA * CD-1 | J:176432 | View | ||||
| hepatocellular carcinoma | Tg(HBVX*,-Myc)#Skp/Tg(HBVX*,-Myc)#Skp | Not Specified | J:81098, J:202732 | View | ||||
| hepatocellular carcinoma | Tg(Mup3-Plau)350-2Eps/? | C57BL/6-Tg(Mup3-Plau)350-2Eps | J:233146 | View | ||||
| hepatocellular carcinoma | Tg(Pklr-Myc)73Ak/0 | B6.Cg-Tg(Pklr-Myc)73Ak | J:184496 | View | ||||
| hepatocellular carcinoma | Tg(Pklr-Myc)73Ak/0 | involves: C57BL/6 * DBA | J:185488 | View | ||||
| hepatocellular carcinoma | TxnipHyplip1/Txnip+ | involves: CAST/Ei * HcB19/Dem | J:112292 | View | ||||
| hepatocellular carcinoma | TxnipHyplip1/TxnipHyplip1 | HcB19/Dem-TxnipHyplip1 | J:112292 | View | ||||
| hepatocellular carcinoma | TxnipHyplip1/TxnipHyplip1 | involves: CAST/Ei * HcB19/Dem | J:112292 | View | ||||
| hepatocellular carcinoma | Uacatm1Kiy/Uacatm1Kiy | B6.129P2-Uacatm1Kiy | J:157049 | View | ||||
| nonpapillary renal cell carcinoma |
Flcntm1Btt/Flcntm1Btt Tg(Cdh16-cre)91Igr/0 |
involves: 129S4/SvJaeSor * C57BL/6 * ICR | J:143922 | View | ||||
| pancreatic carcinoma |
Brca2tm1Brn/Brca2tm1Cam Krastm4Tyj/Kras+ Trp53tm3Tyj/Trp53+ Tg(Pdx1-cre)6Tuv/0 |
involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB/N | J:166678 | View | ||||
| pancreatic carcinoma |
Cdkn2atm4Rdp/Cdkn2atm4Rdp Krastm4Tyj/Kras+ Tg(Pdx1-cre)89.1Dam/0 |
involves: 129S4/SvJae * C57BL/6 * CBA | J:187012 | View | ||||
| pancreatic carcinoma |
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+ Ptf1atm1.1(cre)Cvw/Ptf1a+ Tg(tetO-Kras*G12D)#Rdp/0 Trp53tm1Brn/Trp53+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N | J:186194 | View | ||||
| pancreatic carcinoma |
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+ Ptf1atm1.1(cre)Cvw/Ptf1a+ Tg(tetO-Kras*G12D)#Rdp/0 Trp53tm1Brn/Trp53tm1Brn |
involves: 129P2/OlaHsd * 129S/Sv * 129X1/SvJ * C57BL/6 * FVB/N | J:186194 | View | ||||
| pancreatic carcinoma |
Krastm1Bbd/Kras+ Trp53tm1Brd/Trp53+ Tg(Cela1-tTA)#Eps/? Tg(tetO-cre)3Jig/? |
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * FVB/N | J:119988 | View | ||||
| pancreatic carcinoma |
Krastm1Bbd/Krastm1Bbd Tg(Cela1-tTA)#Eps/? Tg(tetO-cre)3Jig/? |
involves: 129S1/Sv * 129X1/SvJ * FVB/N | J:119988 | View | ||||
| pancreatic carcinoma |
Krastm4Tyj/Kras+ Ptentm1Hwu/Pten+ Tg(Pdx1-cre)89.1Dam/0 |
involves: 129S4/SvJae * BALB/c * C57BL/6 | J:164210 | View | ||||
| pancreatic carcinoma |
Krastm4Tyj/Kras+ Ptentm1Hwu/Ptentm1Hwu Tg(Pdx1-cre)89.1Dam/0 |
involves: 129S4/SvJae * BALB/c * C57BL/6 * CBA | J:164210 | View | ||||
| pancreatic carcinoma |
Krastm4Tyj/Kras+ Ptf1atm1.1(cre)Cvw/Ptf1a+ |
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ | J:87973 | View | ||||
| pancreatic carcinoma |
Krastm4Tyj/Kras+ Ptf1atm1.1(cre)Cvw/Ptf1a+ Tg(MUC1)79.24Gend/0 |
B6.Cg-Krastm4Tyj Ptf1atm1.1(cre)Cvw Tg(MUC1)79.24Gend | J:234412 | View | ||||
| pancreatic carcinoma |
Krastm4Tyj/Kras+ Tg(CAG-Bgeo,-tsA58T)T26Ichi/0 Tg(Pdx1-cre)6Tuv/0 |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB/N | J:214846 | View | ||||
| pancreatic carcinoma |
Krastm4Tyj/Kras+ Tg(Pdx1-cre)6Tuv/0 Trp53tm1Gev/Trp53tm1Gev |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB/N | J:220300 | View | ||||
| pancreatic carcinoma |
Krastm4Tyj/Kras+ Tg(Pdx1-cre)6Tuv/? |
involves: 129S4/SvJae * FVB/N | J:87973 | View | ||||
| pancreatic carcinoma | Tg(Ela1-Myc)158Bri/0 | involves: C57BL/6 * SJL | J:76992 | View | ||||
| pancreatic carcinoma | Tg(Ela1-Myc)159Bri/0 | involves: C57BL/6 * SJL | J:76992 | View | ||||
| pancreatic carcinoma | Tg(Ela1-Myc)160Bri/0 | involves: C57BL/6 * SJL | J:76992 | View | ||||
| renal cell carcinoma |
Nf2tm2Gth/Nf2tm2Gth Tg(Vil1-cre)20Syr/0 |
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 | J:150071 | View | ||||
| skin squamous cell carcinoma | Tg(KRT14-Fyn*)aJsey/0 | involves: C57BL/6 * CBA * FVB/N | J:155536 | View | ||||
| | basal cell carcinoma |
Dicer1tm1Snj/Dicer1tm1Snj Trp53tm1Brn/Trp53+ Tg(KRT5-cre/PGR)1Der/0 |
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR | J:216813 | View | |||
| squamous cell carcinoma |
Dicer1tm1Snj/Dicer1tm1Snj Trp53tm1Brn/Trp53tm1Brn Tg(KRT5-cre/PGR)1Der/0 |
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR | J:216813 | View | ||||
| squamous cell carcinoma |
Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53tm1Brn Tg(KRT14-cre/ERT)20Efu/0 |
involves: 129P2/OlaHsd * 129S4/SvJae * CD-1 | J:172048 | View | ||||
| Transgenes and Other Mutations | adenosquamous lung carcinoma |
Tg(Scgb1a1-rtTA)1Jaw/0 Tg(tetO-ERBB2*)5BKkw/0 |
involves: FVB/N | J:143874 | View | |||
| adenosquamous lung carcinoma |
Tg(Scgb1a1-rtTA)1Jaw/0 Tg(tetO-ERBB2*)26Kkw/0 |
involves: FVB/N | J:143874 | View | ||||
| follicular thyroid carcinoma | Tg(TG-NRAS*Q61K)#Msnt/0 | Not Specified | J:210016 | View | ||||
| hepatocellular carcinoma |
Rb1tm3Tyj/Rb1tm3Tyj Tg(tetO-MYC)36aBop/0 Tg(Cebpb-tTA)5Bjd/0 |
involves: FVB/N * NMRI | J:172430 | View | ||||
| hepatocellular carcinoma | Tg(Alb1HBV)44Bri/0 | C57BL/6J-Tg(Alb1HBV)44Bri/J | J:223921 | View | ||||
| hepatocellular carcinoma | Tg(Alb-E2F1)8Sst/0 | involves: C57BL/6J * CBA/J | J:65354, J:101128, J:170790 | View | ||||
| hepatocellular carcinoma | Tg(Alb-HBx)A112Tfts/0 | involves: C57BL/6 | J:104728 | View | ||||
| hepatocellular carcinoma | Tg(Alb-HRAS*G12V)28Yu/0 | involves: C57BL/6J * CBA/J | J:107083, J:238319 | View | ||||
| hepatocellular carcinoma | Tg(Alb-PDGFC)#Jcam/0 | involves: C57BL/6 | J:211984 | View | ||||
| hepatocellular carcinoma | Tg(Alb-SND1)3aDsar/0 | involves: C57BL/6 * CBA | J:242582 | View | ||||
| hepatocellular carcinoma | Tg(Alb-TAg)1Gjh/0 | C3.Cg-Tg(Alb-TAg)1Gjh | J:105110 | View | ||||
| hepatocellular carcinoma | Tg(Alb-TAg)#Arnd/0 | C3Fe.Cg-Tg(Alb-TAg)#Arnd | J:171880 | View | ||||
| hepatocellular carcinoma |
Tg(Cebpb-tTA)5Bjd/0 Tg(tetO-MYC,-OVAL)#Gtgm/0 |
B6J.Cg-Tg(Cebpb-tTA)5Bjd Tg(tetO-MYC,-OVAL)#Gtgm | J:186226 | View | ||||
| hepatocellular carcinoma | Tg(HBV-HCV)Kko/0 | C57BL/6N-Tg(HBV-HCV)Kko | J:69727 | View | ||||
| hepatocellular carcinoma | Tg(HBx)3Yu/0 | involves: C57BL/6 * DBA | J:56196 | View | ||||
| hepatocellular carcinoma | Tg(Myl2-FGF19)1Dfre/? | involves: FVB | J:77160, J:187236 | View | ||||
| hepatocellular carcinoma | Tg(SERPINA1-TAg)1812Jtsb/0 | involves: C3H * C57BL/6 * ICR | J:101633 | View | ||||
| hepatocellular carcinoma | Tg(SERPINC1-SV40)A1Pbr/0 | involves: C57BL/6 * DBA/2 | J:101541 | View | ||||
| hepatocellular carcinoma | Tg(SERPINC1-SV40)A1Pbr/Tg(SERPINC1-SV40)A1Pbr | involves: C57BL/6 * DBA/2 | J:101541 | View | ||||
| hepatocellular carcinoma |
Tg(tetO-MET)23Rwng/0 Tg(Cebpb-tTA)5Bjd/0 |
involves: FVB/N * NMRI | J:69731 | View | ||||
| hepatocellular carcinoma |
Tg(tetO-MYC)36aBop/0 Tg(Cebpb-tTA)5Bjd/0 |
involves: FVB/N * NMRI | J:93899, J:186226, J:172430 | View | ||||
| hepatocellular carcinoma | X/Tg(SERPINC1-SV40)BPbr | involves: C57BL/6 * DBA/2 | J:101541, J:84204 | View | ||||
| lung adenocarcinoma |
Tg(Scgb1a1-rtTA)1Jaw/0 Tg(tetO-Kras2)12Hev/0 |
involves: 129 * C57BL/6 * FVB/N | J:73468 | View | ||||
| lung adenocarcinoma | Tg(SFTPC-env)1Yhch/0 | FVB/N-Tg(SFTPC-env)1Yhch | J:247986 | View | ||||
| pancreatic carcinoma |
Bcl2l1tm1.1Mam/Bcl2l1tm1.1Mam Tg(Ins2-cre)25Mgn/0 Tg(RIP1-Tag)2Dh/0 |
involves: 129S6/SvEvTac * C57BL/6 * DBA | J:146436 | View | ||||
| pancreatic carcinoma |
Bcl2l1tm1.1Mam/Bcl2l1tm1.1Mam Tg(RIP1-Tag)2Dh/0 |
involves: 129S6/SvEvTac * C57BL/6 * DBA | J:146436 | View | ||||
| pancreatic carcinoma |
Tg(CAG-Bgeo,-tTA,-EGFP)2A11Kuw/0 Tg(Pdx1-cre)6Tuv/0 Tg(tetO-MYC)36Bop/0 |
involves: 129P2/OlaHsd * FVB/N | J:197052 | View | ||||
| pancreatic carcinoma | Tg(Cela1-luc,Cela1-TAg)#Nzh/0 | involves: FVB/N | J:207960 | View | ||||
| pancreatic carcinoma | Tg(Ela1-TAg)18Bri/0 | involves: C57BL/6 * SJL | J:76995 | View | ||||
| pancreatic carcinoma | Tg(Ela1-TAg)19Bri/0 | involves: C57BL/6 * SJL | J:76995 | View | ||||
| pancreatic carcinoma | Tg(Ins2-Tag*,-flpe)#Gne/0 | involves: C57BL/6J | J:187012 | View | ||||
| pancreatic carcinoma | Tg(Ins2-Tag*,-flpe)#Gne/0 | Not Specified | J:188693 | View | ||||
| pancreatic carcinoma | Tg(RIP1-Tag)2Dh/0 | involves: C57BL/6J * DBA/2J | J:50695 | View | ||||
| pancreatic carcinoma | Tg(RIR-Tag)87Dh/0 | involves: C57BL/6J * DBA/2J | J:50695 | View | ||||
| papillary thyroid carcinoma |
Tg(tetO-BRAF*V600E)26Jaf/0 Tg(TG-rtTA)30Jaf/0 |
involves: FVB/N | J:184420 | View | ||||
| papillary thyroid carcinoma | Tg(TG-BRAF*V600E)2Jaf/0 | FVB/N-Tg(TG-BRAF*V600E)2Jaf | J:98550, J:195921 | View | ||||
| papillary thyroid carcinoma | Tg(TG-RET/CCDC6)42Cled/0 | involves: FVB/N | J:93679, J:55883 | View | ||||
| papillary thyroid carcinoma | Tg(TG-RET/NCOA4)3209Rstn/0 | involves: C57BL/6 | J:51366 | View | ||||
| papillary thyroid carcinoma | Tg(TG-TPR/NTRK1)5215Rstn/0 | involves: C3H * C57BL/6 | J:67120 | View | ||||
| prostate adenocarcinoma | Tg(Pbsn-Tag)12T10Rjm/0 | involves: CD-1 | J:68483 | View | ||||
| skin squamous cell carcinoma | Tg(KRT14-HPV16)wt1Dh/0 | either: FVB.Cg-Tg(KRT14-HPV16)wt1Dh or (involves: C57BL/6 * DBA/2 * FVB/N) | J:20130 | View | ||||
| Additional Complex Models | anal canal carcinoma |
Ptentm1Hwu/Ptentm1Hwu Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl Tg(KRT14-cre/ERT)20Efu/0 |
involves: 129 * 129S4/SvJae * C57BL/6 * CD-1 * FVB/N | J:209026 | View | |||
| head and neck squamous cell carcinoma |
Ptentm1Hwu/Ptentm1Hwu Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl Tg(KRT14-cre/ERT)20Efu/0 |
involves: 129 * 129S4/SvJae * C57BL/6 * CD-1 * FVB/N | J:194652 | View | ||||
| head and neck squamous cell carcinoma |
Tg(KRT14-cre)8Brn/0 Tg(KRT5-Akt1*)Jmpa/0 Trp53tm1Brn/Trp53tm1Brn |
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * DBA/2J * FVB/N | J:144831 | View | ||||
| hepatocellular carcinoma |
Col1a1tm1(tetO-URI1)Ndj/Col1a1+ Tg(Cebpb-tTA)#Bjd/0 |
B6.Cg-Col1a1tm1(tetO-URI1)Ndj Tg(Cebpb-tTA)#Bjd | J:217463 | View | ||||
| hepatocellular carcinoma |
Col1a1tm1(tetO-URI1)Ndj/Col1a1tm1(tetO-URI1)Ndj Tg(Cebpb-tTA)#Bjd/0 |
B6.Cg-Col1a1tm1(tetO-URI1)Ndj Tg(Cebpb-tTA)#Bjd | J:217463 | View | ||||
| hepatocellular carcinoma |
Rb1tm3Tyj/Rb1tm3Tyj Rbl1tm1Tyj/Rbl1tm1Tyj Rbl2tm2.1Tyj/Rbl2tm2.1Tyj |
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 | J:177573 | View | ||||
| hepatocellular carcinoma |
Stk3tm1Jav/Stk3tm1Jav Stk4Gt(AJ0315)Wtsi/Stk4Gt(AJ0315)Wtsi Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129 * 129P2/OlaHsd * C57BL/6 * DBA | J:238319 | View | ||||
| hepatocellular carcinoma |
Tg(IRS1)1Mhep/0 Tg(SERPINA1-HBVX)1655Jtsb/0 |
involves: C3H * C57BL/6 * FVB * ICR | J:227278 | View | ||||
| lung non-small cell carcinoma |
Col1a1tm1(tetO-EML4/ALK)Kkw/Col1a1+ Tg(Scgb1a1-rtTA)1Jaw/0 |
involves: 129 * C57BL/6 | J:166724 | View | ||||
| lung non-small cell carcinoma |
Krastm4Tyj/Kras+ Stk11tm1.1Rdp/Stk11tm1.1Rdp |
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * FVB/N | J:124682 | View | ||||
| lung non-small cell carcinoma |
Krastm4Tyj/Kras+ Stk11tm1.1Rdp/Stk11tm1.2Rdp |
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * FVB/N | J:124682 | View | ||||
| lung small cell carcinoma |
Rb1tm2Brn/Rb1tm2Brn Trp53tm1Brn/Trp53tm1Brn |
involves: 129P2/OlaHsd | J:86077, J:157319 | View | ||||
| lung small cell carcinoma |
Rb1tm2Brn/Rb1tm2Brn Trp53tm1Lejo/Trp53tm1Lejo |
involves: 129 | J:187012 | View | ||||
| lung small cell carcinoma |
Rb1tm3Tyj/Rb1tm3Tyj Rbl2tm2Tyj/Rbl2tm2Tyj Trp53tm1Brn/Trp53tm1Brn |
involves: 129P2/OlaHsd * 129S4/SvJae | J:160148 | View | ||||
| lung small cell carcinoma |
Rb1tm3Tyj/Rb1tm3Tyj Trp53tm1Brn/Trp53tm1Brn |
involves: 129P2/OlaHsd * 129S4/SvJae | J:160148 | View | ||||
| lung squamous cell carcinoma |
Nr1h2tm1.1Gstr/Nr1h2tm1.1Gstr Nr1h3tm1.1Gstr/Nr1h3tm1.1Gstr |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:234268 | View | ||||
| pancreatic carcinoma |
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+ Ptf1atm1.1(cre)Cvw/Ptf1a+ Tg(tetO-Kras2)12Hev/0 Trp53tm1Tyj/Trp53+ |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N | J:184378 | View | ||||
| pancreatic carcinoma |
Rb1tm2Brn/Rb1tm2Brn Trp53tm1Brn/Trp53tm1Brn Tg(Ren-cre)#Kwg/0 |
involves: 129 * 129P2/OlaHsd | J:216559 | View | ||||
| pancreatic carcinoma |
Tg(Ela1-Tgfa)150Bri/0 Trp53tm1Tyj/Trp53+ |
involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL | J:67389 | View | ||||
| pancreatic carcinoma |
Tg(Ela1-Tgfa)150Bri/0 Trp53tm1Tyj/Trp53tm1Tyj |
involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL | J:67389 | View | ||||
| pancreatic carcinoma |
Tg(Ela-KRAS*G12D)9Eps/0 Tg(Mt1-TGFBR2*)AM3Epb/0 |
involves: C57BL/6 * FVB | J:231759 | View | ||||
| pancreatic ductal adenocarcinoma |
Cdkn2atm2.1Rdp/Cdkn2a+ Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53tm1Brn Tg(Pdx1-cre)89.1Dam/0 |
involves: 129 * C57BL/6 * CBA * FVB/N | J:108298 | View | ||||
| pancreatic ductal adenocarcinoma |
Cdkn2atm2.1Rdp/Cdkn2atm2.1Rdp Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53+ Tg(Pdx1-cre)89.1Dam/0 |
involves: 129 * C57BL/6 * CBA * FVB/N | J:108298 | View | ||||
| pancreatic ductal adenocarcinoma |
Cdkn2atm2.1Rdp/Cdkn2atm2.1Rdp Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53tm1Brn Tg(Pdx1-cre)89.1Dam/0 |
involves: 129 * C57BL/6 * CBA * FVB/N | J:108298 | View | ||||
| pancreatic ductal adenocarcinoma |
Cdkn2atm4Rdp/Cdkn2atm4Rdp Krastm4Tyj/Kras+ Tg(Pdx1-cre)89.1Dam/0 |
involves: 129S4/SvJae * C57BL/6 * CBA * FVB/N | J:87196, J:108298 | View | ||||
| pancreatic ductal adenocarcinoma |
Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ Hmga2tm1.1Mmw/Hmga2+ Krastm4Tyj/Kras+ Tg(Pdx1-cre)6Tuv/0 Trp53tm2Tyj/Trp53+ |
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6NCrl * FVB/N | J:245611 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm1.1Khai/Kras+ Tg(Pdx1-cre)6Tuv/0 Trp53tm3.1Tyj/Trp53+ |
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * FVB/N | J:276349 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm4Tyj/Kras+ Tg(Pdx1-cre)6Tuv/0 Trp53tm3.1Tyj/Trp53+ |
involves: 129S4/SvJae * C57BL/6 * FVB/N | J:276349 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm4Tyj/Kras+ Tg(Pdx1-cre)6Tuv/0 Usp9xtm1Tuv/Usp9x+ |
involves: 129S4/SvJae * FVB/N | J:186717 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm4Tyj/Kras+ Tg(Pdx1-cre)6Tuv/0 Usp9xtm1Tuv/Y |
involves: 129S4/SvJae * FVB/N | J:186717 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53tm1Brn Tg(Pdx1-cre)89.1Dam/0 |
involves: 129 * C57BL/6 * CBA * FVB/N | J:108298 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm4Tyj/Kras+ Trp53tm2Tyj/Trp53+ Tg(Pdx1-cre)6Tuv/0 |
involves: 129S4/SvJae * C57BL/6 * FVB/N | J:98936 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm5Tyj/Kras+ Pdx1tm1.1(flpo)Most/Pdx1+ Trp53tm1.1Dgk/Trp53+ |
involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * Black Swiss * C57BL/6 | J:248550 | View | ||||
| pancreatic ductal adenocarcinoma |
Krastm5Tyj/Kras+ Pdx1tm1.1(flpo)Most/Pdx1+ Trp53tm1.1Dgk/Trp53tm1.1Dgk |
involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * Black Swiss * C57BL/6 | J:248550 | View | ||||
| prostate adenocarcinoma |
Gt(ROSA)26Sortm1(CAG-AR)Zsu/Gt(ROSA)26Sor+ Tg(Osr1-cre)4Mrt/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N | J:234601 | View | ||||
| prostate adenocarcinoma |
Gt(ROSA)26Sortm1(CAG-AR)Zsu/Gt(ROSA)26Sortm1(CAG-AR)Zsu Tg(Osr1-cre)4Mrt/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N | J:234601 | View | ||||
| salivary gland carcinoma |
Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr Ctnnb1tm1Mmt/Ctnnb1+ Krt14tm1.1(cre)Wbm/Krt14+ |
involves: 129P2/OlaHsd * 129S7/SvEvBrd * 129X1/SvJ | J:199091 | View | ||||
| squamous cell carcinoma |
Krastm4Tyj/Kras+ Smad4tm2.1Cxd/Smad4tm2.1Cxd Tg(Krt1-15-cre/PGR*)22Cot/0 |
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL/J | J:203922 | View | ||||
| thyroid gland carcinoma |
Ptentm1Hwu/Ptentm1Hwu Tg(CAG-EGFP,-PAX8/PPARG)1Rkoe/0 Tg(TPO-cre)1Shk/0 |
involves: 129S4/SvJae * FVB/NCr * FVB/NJ | J:177181 | View | ||||
| thyroid gland carcinoma |
Ptentm2.1Ppp/Ptentm2.1Ppp Trp53tm1Brn/Trp53tm1Brn Tg(TPO-cre)1Shk/0 |
129.Cg-Tg(TPO-cre)1Shk Trp53tm1Brn Ptentm2.1Ppp | J:211100 | View | ||||
|
No similarity to the expected human disease phenotype was found.
|
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | familial medullary thyroid carcinoma | Rettm2.1Cos/Ret+ | involves: 129S1/Sv * C57BL/6J * FVB/N | J:60659 | View | |||
| familial medullary thyroid carcinoma | Rettm2.1Cos/Rettm2.1Cos | involves: 129S1/Sv * C57BL/6J * FVB/N | J:60659 | View | ||||
| skin squamous cell carcinoma | Tg(KRT14-HPV16)wt1Dh/0 | C.Cg-Tg(KRT14-HPV16)wt1Dh | J:20130 | View | ||||
| skin squamous cell carcinoma | Tg(KRT14-HPV16)wt1Dh/0 | either: (involves: C57BL/6 * DBA/2) or (involves: C57BL/6 * DBA/2 * SENCAR * SSIN) | J:20130 | View | ||||