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All mouse models of gastrointestinal system cancer with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | colorectal cancer | ApcMin/Apc+ | C57BL/6J-ApcMin | J:85142 | View | |||
| colorectal cancer | ApcMin/Apc+ | C57BL/6J-ApcMin/J | J:331404 | View | ||||
| colorectal cancer |
ApcMin/Apc+ Ccdc80tm1.1Ftk/Ccdc80tm1.1Ftk |
involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 * C57BL/6J * C57BL/6N | J:216704 | View | ||||
| colorectal cancer |
ApcMin/Apc+ Msh2tm1Mak/Msh2tm1Mak |
involves: 129P2/OlaHsd * C57BL/6J | J:75393, J:200824 | View | ||||
| colorectal cancer | Apctm1Cip/Apc+ | involves: 129P2/OlaHsd * C57BL/6 | J:94108 | View | ||||
| colorectal cancer |
Apctm1Mmt/Apc+ Smad4tm1Mmt/Smad4+ |
involves: 129S2/SvPas * C57BL/6 | J:46242 | View | ||||
| colorectal cancer |
Apctm1Rsmi/Apc+ Tg(Fabp1-cre)1Jig/0 |
involves: 129P2/OlaHsd * FVB/N | J:159883 | View | ||||
| colorectal cancer |
Apctm1Tno/Apc+ Tg(CDX2-cre)101Erf/0 |
involves: 129S4/SvJae * C57BL/6 * SJL | J:126018 | View | ||||
| colorectal cancer |
Apctm2.1Cip/Apc+ Tg(Vil1-cre/ERT2)23Syr/0 |
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 | J:227287 | View | ||||
| colorectal cancer |
Apctm2Rak/Apc+ Krastm1.1Khai/Kras+ Tg(Fabp1-cre)1Jig/0 |
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * FVB/N * SJL | J:276349 | View | ||||
| colorectal cancer |
Apctm2Rak/Apc+ Krastm4Tyj/Kras+ Tg(Fabp1-cre)1Jig/0 |
involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL | J:276349 | View | ||||
| colorectal cancer | Apctm2Rak/Apctm2Rak | involves: 129/Sv * C57BL/6J * SJL | J:156532 | View | ||||
| colorectal cancer |
Apctm2Rak/Apctm2Rak Krastm4Tyj/Kras+ |
involves: 129 * 129S4/SvJae * C57BL/6J * SJL | J:156532 | View | ||||
| gastrointestinal stromal tumor | Kittm1Bpr/Kit+ | either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6) | J:100778 | View | ||||
| gastrointestinal stromal tumor | Kittm1Bpr/Kittm1Bpr | either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6) | J:100778 | View | ||||
| gastrointestinal stromal tumor | Kittm1Shta/Kittm1Shta | involves: 129S6/SvEvTac * C57BL/6 * FVB/N | J:130890 | View | ||||
| gastrointestinal stromal tumor | Kittm2Bsm/Kit+ | involves: 129X1/SvJ * C57BL/6J | J:83616 | View | ||||
| gastrointestinal stromal tumor | Kittm4.1Bsm/Kit+ | involves: 129S1/Sv * C57BL/6J * FVB/N | J:188434 | View | ||||
| hepatocellular carcinoma | Apctm2.1Cip/Apctm2.1Cip | involves: 129P2/OlaHsd * C57BL/6N | J:94721 | View | ||||
| hepatocellular carcinoma | Nr1h4tm1Gonz/Nr1h4tm1Gonz | involves: 129X1/SvJ * C57BL/6 | J:118204, J:170790 | View | ||||
| hepatocellular carcinoma | Nr1h4tm1Gonz/Nr1h4tm1Gonz | involves: 129X1/SvJ * C57BL/6N | J:121075, J:170790 | View | ||||
| intrahepatic cholangiocarcinoma |
Krastm4Tyj/Kras+ Ptentm2Mak/Ptentm2Mak Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA | J:254370 | View | ||||
| intrahepatic cholangiocarcinoma |
Krastm4Tyj/Kras+ Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129S4/SvJae * C57BL/6 * DBA | J:184949 | View | ||||
| intrahepatic cholangiocarcinoma |
Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53+ Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA | J:184949 | View | ||||
| intrahepatic cholangiocarcinoma |
Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53tm1Brn Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA | J:184949 | View | ||||
| | colorectal cancer |
Stat3tm1Dlv/Stat3tm1Dlv Tg(Csf1r-icre)1Jwp/0 |
involves: 129P2/OlaHsd * C57BL/6 * FVB | J:156593 | View | |||
| hepatocellular carcinoma | Abcb4tm1Bor/Abcb4tm1Bor | either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * FVB/N) | J:21232 | View | ||||
| hepatocellular carcinoma | Cdkn1atm1(HBsAg)Xya/Cdkn1a+ | either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * Black Swiss) | J:88078 | View | ||||
| hepatocellular carcinoma | Cdkn1atm1(HBsAg)Xya/Cdkn1atm1(HBsAg)Xya | either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * Black Swiss) | J:88078 | View | ||||
| hepatocellular carcinoma | Cdkn1atm2(HBx)Xya/Cdkn1a+ | either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * Black Swiss) | J:88078 | View | ||||
| hepatocellular carcinoma | Cdkn1atm2(HBx)Xya/Cdkn1atm2(HBx)Xya | either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * Black Swiss) | J:88078 | View | ||||
| hepatocellular carcinoma | Foxm1tm1Rhc/Foxm1tm1Rhc | involves: 129X1/SvJ | J:89472 | View | ||||
| hepatocellular carcinoma | Gnmttm1Ymac/Gnmttm1Ymac | involves: 129 * C57BL/6 | J:146081 | View | ||||
| hepatocellular carcinoma |
Gtf2ird1Tg(Alb1-Myc)166.8Sst/Gtf2ird1+ Tg(Alb-E2F1)8Sst/0 |
involves: C57BL/6 * CBA | J:101128, J:170790 | View | ||||
| hepatocellular carcinoma |
Gtf2ird1Tg(Alb1-Myc)166.8Sst/Gtf2ird1+ Tg(MtTGFA)42Lmb/0 |
involves: C57BL/6 * CBA * CD-1 | J:34434 | View | ||||
| hepatocellular carcinoma | Iqgap2tm1Vs/Iqgap2tm1Vs | involves: 129S4/SvJae | J:205882 | View | ||||
| hepatocellular carcinoma | Krt18tm1Tmm/Krt18tm1Tmm | involves: 129P2/OlaHsd | J:309021 | View | ||||
| hepatocellular carcinoma |
Lect2tm1Ymg/Lect2tm1Ymg Tg(Pklr-Myc)73Ak/0 |
B6.Cg-Lect2tm1Ymg Tg(Pklr-Myc)73Ak | J:184496 | View | ||||
| hepatocellular carcinoma | Mcm9Gt(AW0655)Wtsi/Mcm9Gt(AW0655)Wtsi | involves: 129P2/OlaHsd * C3HeB/FeJ | J:177420 | View | ||||
| hepatocellular carcinoma | Mcm9Gt(AW0655)Wtsi/Mcm9Gt(XG743)Byg | involves: 129P2/OlaHsd * C3HeB/FeJ | J:177420 | View | ||||
| hepatocellular carcinoma | Mcm9Gt(XG743)Byg/Mcm9Gt(XG743)Byg | involves: 129P2/OlaHsd * C3HeB/FeJ | J:177420 | View | ||||
| hepatocellular carcinoma |
Nfe2l1tm1Jefc/Nfe2l1tm1Ywk Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129X1/SvJ * C57BL/6J | J:97188 | View | ||||
| hepatocellular carcinoma |
Ptentm1Hwu/Ptentm1Hwu Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129S4/SvJae * C57BL/6 * DBA | J:218587 | View | ||||
| hepatocellular carcinoma |
Ptentm2Mak/Ptentm2Mak Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * DBA | J:90905 | View | ||||
| hepatocellular carcinoma |
Ptentm2Mak/Ptentm2Mak Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129P2/OlaHsd * C57BL/6 * DBA | J:138099 | View | ||||
| hepatocellular carcinoma |
Sav1tm2.1Dlim/Sav1tm2.1Dlim Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: C57BL/6 * DBA | J:238319 | View | ||||
| hepatocellular carcinoma |
Tcra-Jtm1Tgi/Tcra-Jtm1Tgi Tg(Pklr-Myc)73Ak/0 |
B6.Cg-Tcra-Jtm1Tgi Tg(Pklr-Myc)73Ak | J:184496 | View | ||||
| hepatocellular carcinoma |
Tg(Alb1-Myc)#Sst/0 Tg(MtTGFA)Lmb/0 |
involves: C57BL/6 * CBA * CD-1 | J:176432 | View | ||||
| hepatocellular carcinoma | Tg(HBVX*,-Myc)#Skp/Tg(HBVX*,-Myc)#Skp | Not Specified | J:81098, J:202732 | View | ||||
| hepatocellular carcinoma | Tg(Mup3-Plau)350-2Eps/? | C57BL/6-Tg(Mup3-Plau)350-2Eps | J:233146 | View | ||||
| hepatocellular carcinoma | Tg(Pklr-Myc)73Ak/0 | B6.Cg-Tg(Pklr-Myc)73Ak | J:184496 | View | ||||
| hepatocellular carcinoma | Tg(Pklr-Myc)73Ak/0 | involves: C57BL/6 * DBA | J:185488 | View | ||||
| hepatocellular carcinoma | TxnipHyplip1/Txnip+ | involves: CAST/Ei * HcB19/Dem | J:112292 | View | ||||
| hepatocellular carcinoma | TxnipHyplip1/TxnipHyplip1 | HcB19/Dem-TxnipHyplip1 | J:112292 | View | ||||
| hepatocellular carcinoma | TxnipHyplip1/TxnipHyplip1 | involves: CAST/Ei * HcB19/Dem | J:112292 | View | ||||
| hepatocellular carcinoma | Uacatm1Kiy/Uacatm1Kiy | B6.129P2-Uacatm1Kiy | J:157049 | View | ||||
| salivary gland cancer | Gon4ljusty/Gon4ljusty | C3HeB/FeJ-Gon4ljusty | J:197352 | View | ||||
| stomach cancer | Il6sttm1Ern/Il6sttm1Ern | involves: 129S1/Sv * C57BL/6 | J:87206 | View | ||||
| stomach cancer | Tff1tm1Mrio/Tff1tm1Mrio | involves: 129S2/SvPas | J:84201 | View | ||||
| | stomach cancer |
Cdh1tm2Kem/Cdh1+ Smad4tm2.1Cxd/Smad4tm2.1Cxd Trp53tm1Brn/Trp53tm1Brn Tg(Pdx1-cre)6Tuv/0 |
involves: 129 * C57BL/6 * FVB/N | J:212549 | View | |||
| Transgenes and Other Mutations | colorectal cancer |
Tg(tetO-MYC)36aBop/0 Tg(Cebpb-tTA)5Bjd/0 |
involves: FVB/N * NMRI | J:190067 | View | |||
| esophageal cancer | Tg(ED-L2-IL1RN/IL1B)#Tcw/? | B6.Cg-Tg(ED-L2-IL1RN/IL1B)#Tcw | J:180282 | View | ||||
| hepatocellular carcinoma |
Rb1tm3Tyj/Rb1tm3Tyj Tg(tetO-MYC)36aBop/0 Tg(Cebpb-tTA)5Bjd/0 |
involves: FVB/N * NMRI | J:172430 | View | ||||
| hepatocellular carcinoma | Tg(Alb1HBV)44Bri/0 | C57BL/6J-Tg(Alb1HBV)44Bri/J | J:223921 | View | ||||
| hepatocellular carcinoma | Tg(Alb-E2F1)8Sst/0 | involves: C57BL/6J * CBA/J | J:65354, J:101128, J:170790 | View | ||||
| hepatocellular carcinoma | Tg(Alb-HBx)A112Tfts/0 | involves: C57BL/6 | J:104728 | View | ||||
| hepatocellular carcinoma | Tg(Alb-HRAS*G12V)28Yu/0 | involves: C57BL/6J * CBA/J | J:107083, J:238319 | View | ||||
| hepatocellular carcinoma | Tg(Alb-PDGFC)#Jcam/0 | involves: C57BL/6 | J:211984 | View | ||||
| hepatocellular carcinoma | Tg(Alb-SND1)3aDsar/0 | involves: C57BL/6 * CBA | J:242582 | View | ||||
| hepatocellular carcinoma | Tg(Alb-TAg)1Gjh/0 | C3.Cg-Tg(Alb-TAg)1Gjh | J:105110 | View | ||||
| hepatocellular carcinoma | Tg(Alb-TAg)#Arnd/0 | C3Fe.Cg-Tg(Alb-TAg)#Arnd | J:171880 | View | ||||
| hepatocellular carcinoma |
Tg(Cebpb-tTA)5Bjd/0 Tg(tetO-MYC,-OVAL)#Gtgm/0 |
B6J.Cg-Tg(Cebpb-tTA)5Bjd Tg(tetO-MYC,-OVAL)#Gtgm | J:186226 | View | ||||
| hepatocellular carcinoma | Tg(HBV-HCV)Kko/0 | C57BL/6N-Tg(HBV-HCV)Kko | J:69727 | View | ||||
| hepatocellular carcinoma | Tg(HBx)3Yu/0 | involves: C57BL/6 * DBA | J:56196 | View | ||||
| hepatocellular carcinoma | Tg(Myl2-FGF19)1Dfre/? | involves: FVB | J:77160, J:187236 | View | ||||
| hepatocellular carcinoma | Tg(SERPINA1-TAg)1812Jtsb/0 | involves: C3H * C57BL/6 * ICR | J:101633 | View | ||||
| hepatocellular carcinoma | Tg(SERPINC1-SV40)A1Pbr/0 | involves: C57BL/6 * DBA/2 | J:101541 | View | ||||
| hepatocellular carcinoma | Tg(SERPINC1-SV40)A1Pbr/Tg(SERPINC1-SV40)A1Pbr | involves: C57BL/6 * DBA/2 | J:101541 | View | ||||
| hepatocellular carcinoma |
Tg(tetO-MET)23Rwng/0 Tg(Cebpb-tTA)5Bjd/0 |
involves: FVB/N * NMRI | J:69731 | View | ||||
| hepatocellular carcinoma |
Tg(tetO-MYC)36aBop/0 Tg(Cebpb-tTA)5Bjd/0 |
involves: FVB/N * NMRI | J:93899, J:186226, J:172430 | View | ||||
| hepatocellular carcinoma | X/Tg(SERPINC1-SV40)BPbr | involves: C57BL/6 * DBA/2 | J:101541, J:84204 | View | ||||
| stomach cancer | Tg(CEACAM5-Tag)L5496Wzm/0 | involves: C57BL/6 * CBA | J:62581 | View | ||||
| stomach cancer | Tg(Ins1-GAS)1Sbr/0 | involves: FVB/NTac | J:59575 | View | ||||
| Additional Complex Models | anal canal carcinoma |
Ptentm1Hwu/Ptentm1Hwu Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl Tg(KRT14-cre/ERT)20Efu/0 |
involves: 129 * 129S4/SvJae * C57BL/6 * CD-1 * FVB/N | J:209026 | View | |||
| colorectal cancer |
Il10tm1Cgn/Il10tm1Cgn Tg(MUC1)79.24Gend/0 |
B6.Cg-Il10tm1Cgn Tg(MUC1)79.24Gend | J:149347 | View | ||||
| colorectal cancer |
Rab25tm1Jrgo/Rab25tm1Jrgo Smad3tm1Par/Smad3+ |
129-Rab25tm1Jrgo Smad3tm1Par | J:158733 | View | ||||
| duodenum cancer |
B3gnt6tm1Lx/B3gnt6tm1Lx C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc Tg(Vil1-cre)997Gum/0 |
involves: 129S1/Sv * C57BL/6J * SJL | J:239765 | View | ||||
| duodenum cancer |
B3gnt6tm1Lx/B3gnt6tm1Lx C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc Tg(Vil1-cre/ERT2)23Syr/0 |
involves: 129S1/Sv * C57BL/6 * C57BL/6J * DBA/2 | J:23965 | View | ||||
| hepatocellular carcinoma |
Col1a1tm1(tetO-URI1)Ndj/Col1a1+ Tg(Cebpb-tTA)#Bjd/0 |
B6.Cg-Col1a1tm1(tetO-URI1)Ndj Tg(Cebpb-tTA)#Bjd | J:217463 | View | ||||
| hepatocellular carcinoma |
Col1a1tm1(tetO-URI1)Ndj/Col1a1tm1(tetO-URI1)Ndj Tg(Cebpb-tTA)#Bjd/0 |
B6.Cg-Col1a1tm1(tetO-URI1)Ndj Tg(Cebpb-tTA)#Bjd | J:217463 | View | ||||
| hepatocellular carcinoma |
Rb1tm3Tyj/Rb1tm3Tyj Rbl1tm1Tyj/Rbl1tm1Tyj Rbl2tm2.1Tyj/Rbl2tm2.1Tyj |
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 | J:177573 | View | ||||
| hepatocellular carcinoma |
Stk3tm1Jav/Stk3tm1Jav Stk4Gt(AJ0315)Wtsi/Stk4Gt(AJ0315)Wtsi Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129 * 129P2/OlaHsd * C57BL/6 * DBA | J:238319 | View | ||||
| hepatocellular carcinoma |
Tg(IRS1)1Mhep/0 Tg(SERPINA1-HBVX)1655Jtsb/0 |
involves: C3H * C57BL/6 * FVB * ICR | J:227278 | View | ||||
| oral cavity cancer |
Krastm4Tyj/Kras+ Tg(CAG-HPV16E6E7,-luc)#Mspi/0 Tg(KRT14-cre/ERT)20Efu/0 |
involves: 129S4/SvJae * C57BL/6 * CD-1 * FVB/N * FVB/NJ | J:210533 | View | ||||
| salivary gland carcinoma |
Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr Ctnnb1tm1Mmt/Ctnnb1+ Krt14tm1.1(cre)Wbm/Krt14+ |
involves: 129P2/OlaHsd * 129S7/SvEvBrd * 129X1/SvJ | J:199091 | View | ||||
| stomach cancer |
Tg(Krt19-Ptgs2,Krt19-Ptges)8Tko/0 Tg(Krt19-Wnt1)2Maos/0 |
involves: C3H * C57BL/6 | J:116782 | View | ||||