Excel File Text File All mouse models of lipid metabolism disorder with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      autosomal recessive hypercholesterolemia Ldlrap1Gt(OST149604)Lex/Ldlrap1Gt(OST149604)Lex involves: 129S5/SvEvBrd * C57BL/6 J:102291 View
autosomal recessive hypercholesterolemia Ldlrap1tm1Her/Ldlrap1tm1Her involves: 129S6/SvEvTac J:84694 View
carnitine palmitoyltransferase I deficiency Cpt1atm1Pwo/Cpt1a+ either: 129S6/SvEvTac-Cpt1atm1Pwo or (involves: 129S6/SvEvTac * C57BL/6NTac) J:101934 View
chylomicron retention disease Sar1bem1Emle/Sar1b+ C57BL/6N-Sar1bem1Emle J:319817 View
chylomicron retention disease Sar1bem2Emle/Sar1b+ C57BL/6N-Sar1bem2Emle J:319817 View
congenital adrenal hyperplasia Cyp11b1tm1Chjk/Cyp11b1tm1Chjk involves: 129P2/OlaHsd * C57BL/6J J:147610 View
congenital adrenal hyperplasia Startm1Klp/Startm1Klp involves: 129P2/OlaHsd J:43589, J:55588, J:64337 View
congenital bile acid synthesis defect 5 Abcd3tm1Safe/Abcd3tm1Safe involves: 129S4/SvJae * C57BL/6J J:217065 View
familial hypercholesterolemia Apobec1tm1Ddsn/Apobec1tm1Ddsn
Ldlrtm1Her/Ldlrtm1Her		 involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 J:49125 View
familial hypercholesterolemia LdlrHlb301/Ldlr+ C57BL/6J-LdlrHlb301/J J:82961 View
familial hypercholesterolemia LdlrHlb301/LdlrHlb301 C57BL/6J-LdlrHlb301/J J:82961 View
familial hypercholesterolemia Ldlrtm1Her/Ldlrtm1Her involves: 129S7/SvEvBrd J:84694 View
familial hypercholesterolemia Ldlrtm1Her/Ldlrtm1Her involves: 129S7/SvEvBrd * C57BL/6 J:102291 View
familial hypercholesterolemia Ldlrtm1Her/Ldlrtm1Her
Lepob/Lepob		 B6.Cg-Lepob Ldlrtm1Her J:72027 View
familial hypercholesterolemia Ldlrtm1Her/Ldlrtm1Her
Tg(Il1rn)1Dih/Tg(Il1rn)1Dih		 involves: 129S7/SvEvBrd * C57BL/6 * CBA J:76336 View
familial lipoprotein lipase deficiency Lpltm1Bres/Lpl+ involves: 129S4/SvJae * C57BL/6J J:30062 View
familial lipoprotein lipase deficiency Lpltm1Bres/Lpltm1Bres involves: 129S4/SvJae * C57BL/6J J:30062 View
familial lipoprotein lipase deficiency Lpltm1Sem/Lpl+ involves: 129P2/OlaHsd * C57BL/6J J:25652 View
familial lipoprotein lipase deficiency Lpltm1Sem/Lpltm1Sem involves: 129P2/OlaHsd * C57BL/6J J:25652 View
medium chain acyl-CoA dehydrogenase deficiency Acadmtm1Uab/Acadmtm1Uab involves: 129P2/OlaHsd * C57BL/6 J:115759 View
Norum disease Lcattm1Nsa/Lcat+ involves: 129X1/SvJ * C57BL/6J J:39237 View
Norum disease Lcattm1Nsa/Lcattm1Nsa involves: 129X1/SvJ * C57BL/6J J:39237 View
Refsum disease Phyhtm1Safe/Phyhtm1Safe involves: 129P2/OlaHsd * 129X1/SvJ * Black Swiss * FVB/N J:142512 View
short chain acyl-CoA dehydrogenase deficiency Acadsdel-J/Acadsdel-J involves: BALB/cByJ J:9743 View
Smith-Lemli-Opitz syndrome Dhcr7tm1.1Sbpa/Dhcr7tm1.1Sbpa
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+		 B6.Cg-Dhcr7tm1.1Sbpa Speer6-ps1Tg(Alb-cre)21Mgn J:303316 View
Smith-Lemli-Opitz syndrome Dhcr7tm1Fdp/Dhcr7tm1Fdp involves: 129S4/SvJae J:68084, J:165301 View
Smith-Lemli-Opitz syndrome Dhcr7tm1Fdp/Dhcr7tm2Fdp involves: 129S4/SvJae J:106758 View
Smith-Lemli-Opitz syndrome Dhcr7tm1Gst/Dhcr7tm1Gst involves: 129P2/OlaHsd J:71611 View
Smith-Lemli-Opitz syndrome Dhcr7tm2Fdp/Dhcr7tm2Fdp involves: 129S4/SvJae J:106758 View
Tangier disease Abca1tm1.1Jp/Abca1tm1.1Jp involves: 129S6/SvEvTac * C57BL/6 J:98093 View
Tangier disease Abca1tm1Blt/Abca1tm1Blt C57BL/6-Abca1tm1Blt J:95088 View
Tangier disease Abca1tm1Jdm/Abca1tm1Jdm DBA/1LacJ-Abca1tm1Jdm J:61679 View
Tangier disease Abca1tm1Jp/Abca1tm1Jp
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+		 involves: 129S6/SvEvTac * B6.Cg-Tg(Alb-cre)21Mgn/J J:98093 View
Tangier disease Abca1tm1Wpfl/Abca1tm1Wpfl involves: 129P2/OlaHsd * C57BL/6J J:64390 View
Tangier disease Abca1tm2Jp/Abca1+
Tg(APOA1)427Bres/?		 involves: 129X1/SvJ * C57BL/6J * CBA/J J:104719 View
Tangier disease Abca1tm2Jp/Abca1tm2Jp
Tg(APOA1)427Bres/?		 involves: 129X1/SvJ * C57BL/6J * CBA/J J:104719 View
very long chain acyl-CoA dehydrogenase deficiency Acadvltm1Uab/Acadvltm1Uab involves: 129S6/SvEvTac * C57BL/6 J:72193 View
very long chain acyl-CoA dehydrogenase deficiency Acadvltm1Vje/Acadvltm1Vje involves: 129/Sv * Black Swiss * C57BL/6 J:106714 View
very long chain acyl-CoA dehydrogenase deficiency Acadvltm1Vje/Acadvltm1Vje involves: 129/Sv * C57BL/6 J:98627, J:102010 View
      chylomicron retention disease PitpnaGt(OST1152)Lex/PitpnaGt(OST1152)Lex involves: 129S5/SvEvBrd J:85204 View
chylomicron retention disease Pitpnatm1Vab/Pitpnatm1Vab involves: 129S7/SvEvBrd J:85204 View
familial hypobetalipoproteinemia 2 Apobtm1Mae/Apob+ involves: 129P2/OlaHsd * C57BL/6J J:36426, J:113171 View
familial hypobetalipoproteinemia 2 Apobtm1Mae/Apobtm1Mae involves: 129P2/OlaHsd * C57BL/6J J:36426 View
very long chain acyl-CoA dehydrogenase deficiency Acadltm1Uab/Acadltm1Uab involves: 129S6/SvEvTac * C57BL/6NTac J:51660 View
      familial combined hyperlipidemia Apoetm1Unc/Apoetm1Unc
Lpltm1Sem/Lpltm1Sem		 involves: 129P2/OlaHsd J:151434 View
Transgenes and
Other Mutations		     Tangier disease Tg(ALB-cre,CMV-rtTA)#Wcyy/0
Tg(CMV-EGFP,Rnu6-siAbca1)#Wcyy/0		 involves: ICR J:93624 View
Additional
Complex
Models		     familial combined hyperlipidemia Ldlrtm1Her/Ldlrtm1Her
Tg(APOC3)3707Bres/?		 involves: 129S7/SvEvBrd * C57BL/6J * CBA/J J:37861 View
familial hypercholesterolemia Gt(ROSA)26Sortm1.1(Alb-PCSK9)Mby/Gt(ROSA)26Sor+ involves: C57BL/6 * C57BL/6N J:280156 View
lipid metabolism disorder Elovl4tm1Wked/Elovl4tm1Wked
Tg(IVL-Elovl4)#Wked/0
Tg(KRT14-Elovl4)#Mpag/0		 involves: 129 * C57BL/6 J:277065 View

       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      familial combined hyperlipidemia Tnfrsf1btm1Imx/Tnfrsf1btm1Imx involves: 129S7/SvEvBrd * C57BL/6 J:45147 View